Abstract:
:The v-erb B protein of avian erythroblastosis virus (AEV) possesses an associated protein kinase activity in vitro. Analysis of temperature-sensitive mutants, and nonconditional host range mutants of AEV demonstrated that there was no simple correlation between this autophosphorylation activity and the transformation ability of the various AEV mutants. These data suggest that although this kinase activity may be central to transformation by AEV it is in itself insufficient.
journal_name
Virologyjournal_title
Virologyauthors
Hayman MJ,Kitchener G,Knight J,McMahon J,Watson R,Beug Hdoi
10.1016/0042-6822(86)90287-4subject
Has Abstractpub_date
1986-04-15 00:00:00pages
270-5issue
1eissn
0042-6822issn
1096-0341journal_volume
150pub_type
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