Ross River virus envelope glycans contribute to disease through activation of the host complement system.

abstract：:Immunodeficiency caused by HIV infection probably results from profound dysregulation of normal T lymphocyte properties by the virus. Despite description of the virus cytopathicity and numerous modifications in T cell functions, such as perturbation of antigen receptor signaling, CD4 downregulation, and induction of a...

journal_title：Virology

authors： Lefebvre JC,Giordanengo V,Doglio A,Cagnon L,Breittmayer JP,Peyron JF,Lesimple J

更新日期：1994-03-01 00:00:00

abstract：:Infectious bronchitis virus (IBV) produces six subgenomic (sg) mRNAs, each containing a 64 nucleotide (nt) leader sequence, derived from the 5' end of the genome by a discontinuous process. Several putative functional domains such as a papain-like proteinase (PL(pro)), main protease (M(pro)), RNA-dependent RNA polymer...

journal_title：Virology

authors： Mondal SP,Cardona CJ

更新日期：2004-06-20 00:00:00

abstract：:Tobacco (Nicotiana edwardsonii and N. benthamiana) protoplasts infected with the plant rhabdovirus sonchus yellow net virus (SYNV) were found to be suitable for studies of replication. SYNV messenger RNAs could be detected within 2 hr postinoculation (PI), accumulated to a maximum within 24 hr, and subsequently declin...

journal_title：Virology

authors： Jones RW,Jackson AO

更新日期：1990-12-01 00:00:00

abstract：:We describe here the transduction of murine hematopoietic progenitor cells with the dominant selectable neomycin drug-resistance (Neo) gene using a recombinant adeno-associated virus (AAV) vector. Successful transformation of progenitor cells to drug resistance was determined to be approximately 1.5% by colony formati...

journal_title：Virology

authors： LaFace D,Hermonat P,Wakeland E,Peck A

更新日期：1988-02-01 00:00:00

abstract：:A subtype of human papillomavirus 5 (HPV-5b) is closely associated with carcinomas in the disease epidermodysplasia verruciformis (EV). The complete genome was cloned from virus particles in benign lesions of a patient with EV and sequenced: it was 7779 nucleotides long and consisted of six open reading frames (ORFs) ...

journal_title：Virology

authors： Yabe Y,Sakai A,Hitsumoto T,Kato H,Ogura H

更新日期：1991-08-01 00:00:00

abstract：:The emergence and re-emergence of Zika virus (ZIKV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas worldwide. Despite these burdens, antiviral therapies do not exist, and inhibitors of ZIKV are therefore urgently needed. To...

journal_title：Virology

authors： Chen H,Lao Z,Xu J,Li Z,Long H,Li D,Lin L,Liu X,Yu L,Liu W,Li G,Wu J

更新日期：2020-07-01 00:00:00

abstract：:RNA copies, synthesized in vitro, of the virulent satellite (RNA C) of turnip crinkle virus (TCV) infect plants when coinoculated with helper virus RNA. RNA C is a small linear RNA of about 355 bases which intensifies TCV symptoms in infected plants. Full-length cDNA copies of the satellite were inserted in an express...

journal_title：Virology

authors： Simon AE,Howell SH

更新日期：1987-01-01 00:00:00

abstract：:Flaviviruses are RNA viruses that constitute a worrisome threat to global human and animal health. In Europe, West Nile virus (WNV) outbreaks have dramatically increased in number and severity in recent years, with dozens of human and horse deaths and a high avian mortality across the continent. Besides WNV, the only ...

journal_title：Virology

authors： Blázquez AB,Escribano-Romero E,Martín-Acebes MA,Petrovic T,Saiz JC

更新日期：2015-08-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (MHV-68) replicates robustly in cell culture, providing a model for studying viral genome replication during de novo infection of tumor-associated herpesviruses. We have previously identified a 1.25-kb origin of lytic replication (oriLyt) for MHV-68. To further investigate the molecular mech...

journal_title：Virology

authors： Gong D,Qi J,Arumugaswami V,Sun R,Deng H

更新日期：2009-05-10 00:00:00

abstract：:Classical swine fever virus (CSFV) is a positive-sense RNA virus with a high degree of genetic variability among isolates. High diversity is also found in virulence, with strains covering the complete spectrum from avirulent to highly virulent. The underlying genetic determinants are far from being understood. Since R...

journal_title：Virology

authors： Töpfer A,Höper D,Blome S,Beer M,Beerenwinkel N,Ruggli N,Leifer I

更新日期：2013-03-30 00:00:00

abstract：:Alternative splicing of pre-mRNAs plays a critical role in maximizing the coding capacity of the small parvovirus genome. The small-intron region of minute virus of mice (MVM) pre-mRNAs undergoes an unusual pattern of overlapping alternative splicing, using two donors, D1 and D2, and two acceptors, A1 and A2, within a...

journal_title：Virology

authors： Haut DD,Pintel DJ

更新日期：1999-05-25 00:00:00

abstract：:Porcine circovirus type 2 (PCV2) is the causative agent of an emerging swine disease, postweaning multisystemic wasting syndrome. In this work, the RNAs of PCV2 synthesized during productive infection in porcine kidney cells were characterized. A total of nine RNAs were detected. They include the viral capsid protein ...

journal_title：Virology

authors： Cheung AK

更新日期：2003-01-05 00:00:00

abstract：:Frog virus 3 (FV3) is the type species member of the genus Ranavirus (family Iridoviridae). To better understand the molecular mechanisms involved in the replication of FV3, including transcription of its highly methylated DNA genome, we have determined the complete nucleotide sequence of the FV3 genome. The FV3 genom...

journal_title：Virology

authors： Tan WG,Barkman TJ,Gregory Chinchar V,Essani K

更新日期：2004-05-20 00:00:00

abstract：:When DNase-digested calf thymus DNA is used as primer, the RNA-directed DNA polymerase of avian myeloblastosis virus will accept potato spindle tuber viroid (PSTV) as a template for DNA synthesis. The DNA obtained hybridizes specifically to PSTV and low molecular weight RNA isolated from PSTV-infected plants; no hybri...

journal_title：Virology

authors： Owens RA

更新日期：1978-09-01 00:00:00

abstract：:In benign squamous lesions and in organotypic epithelial cultures, the human papillomavirus (HPV) E6 and E7 genes are transcriptionally up-regulated in differentiated, spinous keratinocytes. We previously identified sequence elements in the enhancer-promoter regions of HPV types 18 and 11 important for this promoter r...

journal_title：Virology

authors： Zhao W,Chow LT,Broker TR

更新日期：1999-01-20 00:00:00

abstract：:The 94-kDa virion-associated RNA-dependent RNA polymerase (RdRp) is present in infectious pancreatic necrosis virus in two forms: (i) as a free polypeptide (VP1) and (ii) as a genome linked protein (VPg) (J. G. Calvert et al., 1991, J. Gen. Virol. 72, 2563-2567). VP1 was guanylylated in vitro by incubating purified vi...

journal_title：Virology

authors： Dobos P

更新日期：1995-04-01 00:00:00

abstract：:It has been widely demonstrated that the human immunodeficiency virus type 1 (HIV-1) envelope, specifically the V3 loop of the gp120 spike, evolves to facilitate adaptation to different cellular populations within an infected host. Less energy has been directed at determining whether the viral promoter, designated the...

journal_title：Virology

authors： McAllister JJ,Phillips D,Millhouse S,Conner J,Hogan T,Ross HL,Wigdahl B

更新日期：2000-09-01 00:00:00

abstract：:Retrons are unusual, reverse transcriptase-encoding elements found in bacteria. Although there are a number of indications that retrons are mobile elements, their transposition has not been observed. The Escherichia coli retrons Ec67 and Ec86 are different retrons inserted at the same site and we have further characte...

journal_title：Virology

authors： Dodd IB,Egan JB

更新日期：1996-05-01 00:00:00

abstract：:Mouse hybridomas which produce monoclonal antibodies to the Autographa californica nuclear polyhedrosis virus (AcNPV) have been prepared and the protein to which each is directed has been determined. The antibody produced by clones 3F3 and 5E9 specifically bound polyhedron protein of MW 32,000 when used in immunoadsor...

journal_title：Virology

authors： Roberts PL,Naser W

更新日期：1982-10-30 00:00:00

abstract：:A previous study suggested that the genomes of the arenaviruses native to North America are a product of genetic recombination between New World arenaviruses with significantly different phylogenetic histories. The purpose of this study was to extend our knowledge of the principal host relationships and evolutionary h...

journal_title：Virology

authors： Cajimat MN,Milazzo ML,Hess BD,Rood MP,Fulhorst CF

更新日期：2007-10-25 00:00:00

abstract：:Lymphoid cell lines were derived from three avian leukosis virus (ALV)-induced lymphomas. These cell lines contained proviral DNA sequences integrated upstream from the c-myc proto-oncogene, expressed increased levels of c-myc RNA, and were tumorigenic in syngeneic animals. While cell surface immunoglobulin (IgM) was ...

journal_title：Virology

authors： Baba TW,Giroir BP,Humphries EH

更新日期：1985-07-15 00:00:00

abstract：:Given dengue virus (DENV) genome austerity, it uses cellular molecules and structures for virion entry, translation and replication of the genome. NS1 is a multifunctional protein key to viral replication and pathogenesis. Identification of cellular proteins that interact with NS1 may help in further understanding the...

journal_title：Virology

authors： Cervantes-Salazar M,Angel-Ambrocio AH,Soto-Acosta R,Bautista-Carbajal P,Hurtado-Monzon AM,Alcaraz-Estrada SL,Ludert JE,Del Angel RM

更新日期：2015-10-01 00:00:00

abstract：:The amino acid sequence of the fiber from adenovirus type 5 has been deduced from the nucleotide sequence of the fiber gene. This sequence is compared with that of adenovirus type 2, a closely related serotype. We find 69% homology for the fiber protein whereas the known nonstructural proteins of these two serotypes h...

journal_title：Virology

authors： Chroboczek J,Jacrot B

更新日期：1987-12-01 00:00:00

abstract：:We have previously demonstrated that the bZIP transcription factor CREB-2, also called ATF-4, trans-activates, in association with the viral protein Tax, the human T-cell leukemia virus type I (HTLV-I) promoter. In this study, we have examined whether CREB-2 acetylation affects transcriptional activation mediated by T...

journal_title：Virology

authors： Gachon F,Devaux C,Mesnard JM

更新日期：2002-08-01 00:00:00

abstract：:We cloned the complete complementary DNA of an isolate of the hepatitis C virus, HCV-S1, into a tetracycline-inducible expression vector and stably transfected it into two human hepatoma cell lines, Huh7 and HepG2. Twenty-six Huh7 and two HepG2-positive clones were obtained after preliminary screening. Two Huh7 (SH-7 ...

journal_title：Virology

authors： Lim SP,Soo HM,Tan YH,Brenner S,Horstmann H,MacKenzie JM,Ng ML,Lim SG,Hong Wj

更新日期：2002-11-10 00:00:00

abstract：:The pe38 gene product of Autographa californica M nucleopolyhedrovirus (AcMNPV) has been shown to be involved in transcriptionally transactivating viral genes and augmenting viral DNA replication in transient assays. To assess the role of pe38 during infection, we generated a knockout virus, Delta pe38-E9/E9, in which...

journal_title：Virology

authors： Milks ML,Washburn JO,Willis LG,Volkman LE,Theilmann DA

更新日期：2003-06-05 00:00:00

abstract：:The coat protein (CP) of alfalfa mosaic virus (AMV) strain 425 assembles to bacilliform or rod-shaped particles in the presence of nucleic acids or to T = 1 empty icosahedral particles in the absence of nucleic acids. To study the determinants of CP assembly, recombinant CPs (rCPs) that contained a (His)(6) region wer...

journal_title：Virology

authors： Choi J,Loesch-Fries LS

更新日期：1999-07-20 00:00:00

abstract：:The interaction of parvovirus minute virus of mice (prototype strain, MVMp) with simian virus 40 (SV40)-transformed human cells (NB-E) was investigated by means of transfection with MVMp molecular clones derived from the infectious recombinant plasmid (pMM984). pMM984 inhibits stable transformation of NB-E cells to ge...

journal_title：Virology

authors： Brandenburger A,Legendre D,Avalosse B,Rommelaere J

更新日期：1990-02-01 00:00:00

abstract：:A combination of linker scanning mutagenesis and deletional analyses has been used to determine the role of individual DNA-protein binding sites on expression from the hepatitis B virus (HBV) enhancer I-X promoter (map position (mp) 1042-1354, HBV adw2). Linker scanning mutation of the EF-C site caused a 67.5% drop in...

journal_title：Virology

authors： Gustin K,Shapiro M,Lee W,Burk RD

更新日期：1993-04-01 00:00:00

abstract：:Particles purified from the liver of hepatitis B virus-infected patients were previously shown by us to incorporate 32P-deoxynucleotides into viral DNA and DNA-RNA hybrid molecules when incubated in a DNA polymerase reaction mixture. In this investigation, similar particles from duck and ground squirrel livers infecte...

journal_title：Virology

authors： Miller RH,Marion PL,Robinson WS

更新日期：1984-11-01 00:00:00