Abstract:
:The spectrum of kidney disease-associated monoclonal immunoglobulin and plasma cell malignancies is remarkably broad and encompasses nearly all nephropathologic entities. Multiple myeloma with kidney impairment at presentation is a medical emergency since the recovery of kidney function is associated with survival benefits. In most cases, kidney impairment may be the first clinical manifestation of malignant plasma cell dyscrasias like multiple myeloma and light chain amyloidosis. Multiple myeloma per se cannot be considered a main risk factor for developing acute kidney injury following intravascular administration of iodinated contrast media. The risk is increased by comorbidities such as chronic kidney disease, diabetes, hypercalcemia, dehydration, and use of nephrotoxic drugs. Before the administration of contrast media, the current recommended laboratory tests for assessing kidney function are serum creatinine measurement and the estimation of glomerular filtration rate by using the CKD-EPI equation. The assessment of Bence Jones proteinuria is unnecessary for evaluating the risk of kidney failure in patients with multiple myeloma, since this test cannot be considered a surrogate biomarker of kidney function.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Mussap M,Merlini Gdoi
10.1155/2014/167125subject
Has Abstractpub_date
2014-01-01 00:00:00pages
167125eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
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journal_title:BioMed research international
pub_type: 杂志文章
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:BioMed research international
pub_type: 杂志文章,meta分析
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更新日期:2018-11-14 00:00:00
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journal_title:BioMed research international
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更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2016/7658981
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更新日期:2019-12-21 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/208017
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3870508
更新日期:2018-05-17 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/182353
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:BioMed research international
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章
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journal_title:BioMed research international
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pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00