Pathogenesis of renal failure in multiple myeloma: any role of contrast media?

Abstract:

:The spectrum of kidney disease-associated monoclonal immunoglobulin and plasma cell malignancies is remarkably broad and encompasses nearly all nephropathologic entities. Multiple myeloma with kidney impairment at presentation is a medical emergency since the recovery of kidney function is associated with survival benefits. In most cases, kidney impairment may be the first clinical manifestation of malignant plasma cell dyscrasias like multiple myeloma and light chain amyloidosis. Multiple myeloma per se cannot be considered a main risk factor for developing acute kidney injury following intravascular administration of iodinated contrast media. The risk is increased by comorbidities such as chronic kidney disease, diabetes, hypercalcemia, dehydration, and use of nephrotoxic drugs. Before the administration of contrast media, the current recommended laboratory tests for assessing kidney function are serum creatinine measurement and the estimation of glomerular filtration rate by using the CKD-EPI equation. The assessment of Bence Jones proteinuria is unnecessary for evaluating the risk of kidney failure in patients with multiple myeloma, since this test cannot be considered a surrogate biomarker of kidney function.

journal_name

Biomed Res Int

authors

Mussap M,Merlini G

doi

10.1155/2014/167125

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

167125

eissn

2314-6133

issn

2314-6141

journal_volume

2014

pub_type

杂志文章,评审
  • Histochemical Study of the Rat Uterine Glycoconjugate Alteration following Treatment with Exogenous Gonadotropic Hormones during the Implantation Period.

    abstract::One of the female causes of infertility is anovulation which is treatable with gonadotropin hormones. These hormones affect the molecular organization of the uterus such as glycoconjugates that are the first site of contact between the blastocyst and the uterus. The objective of this project was to study the alteratio...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/3967427

    authors: Aliabadi E,Makoolati Z,Talaei-Khozani T,Ardekani FM,Aliabadi A

    更新日期:2020-12-04 00:00:00

  • Cigarette Smoke Induced Lung Barrier Dysfunction, EMT, and Tissue Remodeling: A Possible Link between COPD and Lung Cancer.

    abstract::Chronic obstructive pulmonary disease (COPD) and lung cancer, closely related to smoking, are major lung diseases affecting millions of individuals worldwide. The generated gas mixture of smoking is proved to contain about 4,500 components such as carbon monoxide, nicotine, oxidants, fine particulate matter, and aldeh...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/2025636

    authors: Hou W,Hu S,Li C,Ma H,Wang Q,Meng G,Guo T,Zhang J

    更新日期:2019-06-24 00:00:00

  • Durable Mechanical Circulatory Support versus Organ Transplantation: Past, Present, and Future.

    abstract::For more than 30 years, heart transplantation has been a successful therapy for patients with terminal heart failure. Mechanical circulatory support (MCS) was developed as a therapy for end-stage heart failure at a time when cardiac transplantation was not yet a useful treatment modality. With the more successful outc...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/849571

    authors: Anand J,Singh SK,Antoun DG,Cohn WE,Frazier OH,Mallidi HR

    更新日期:2015-01-01 00:00:00

  • Suggestions for Radiation Oncologists during the COVID-19 Pandemic.

    abstract::SARS-CoV-2 pandemic and COVID-19 diffusion have recently become an international public health emergency. Cancer patients, as a frail population, are particularly exposed to the risk related to infections. The clinical decision-making process and the organizational workflow of radiotherapy department should be revised...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/4892382

    authors: Franco P,Kochbati L,Siano M,De Bari B

    更新日期:2020-05-26 00:00:00

  • Molecular mechanisms involved in the pathogenesis of alphavirus-induced arthritis.

    abstract::Arthritogenic alphaviruses, including Ross River virus (RRV), Chikungunya virus (CHIKV), Sindbis virus (SINV), Mayaro virus (MAYV), O'nyong-nyong virus (ONNV), and Barmah Forest virus (BFV), cause incapacitating and long lasting articular disease/myalgia. Outbreaks of viral arthritis and the global distribution of the...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/973516

    authors: Assunção-Miranda I,Cruz-Oliveira C,Da Poian AT

    更新日期:2013-01-01 00:00:00

  • Cloning and expression of synthetic genes encoding the broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris.

    abstract::We have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris. Synthetic genes, matching the codon usage of P. pastoris, were designed from the known mature amino acid sequence of these bacter...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/767183

    authors: Arbulu S,Jiménez JJ,Gútiez L,Cintas LM,Herranz C,Hernández PE

    更新日期:2015-01-01 00:00:00

  • Current opportunities and challenges of magnetic resonance spectroscopy, positron emission tomography, and mass spectrometry imaging for mapping cancer metabolism in vivo.

    abstract::Cancer is known to have unique metabolic features such as Warburg effect. Current cancer therapy has moved forward from cytotoxic treatment to personalized, targeted therapies, with some that could lead to specific metabolic changes, potentially monitored by imaging methods. In this paper we addressed the important as...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/625095

    authors: Lin G,Chung YL

    更新日期:2014-01-01 00:00:00

  • Application of Compressive Sensing to Ultrasound Images: A Review.

    abstract::Compressive sensing (CS) offers compression of data below the Nyquist rate, making it an attractive solution in the field of medical imaging, and has been extensively used for ultrasound (US) compression and sparse recovery. In practice, CS offers a reduction in data sensing, transmission, and storage. Compressive sen...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/7861651

    authors: Yousufi M,Amir M,Javed U,Tayyib M,Abdullah S,Ullah H,Qureshi IM,Alimgeer KS,Akram MW,Khan KB

    更新日期:2019-11-15 00:00:00

  • Multiblock discriminant analysis for integrative genomic study.

    abstract::Human diseases are abnormal medical conditions in which multiple biological components are complicatedly involved. Nevertheless, most contributions of research have been made with a single type of genetic data such as Single Nucleotide Polymorphism (SNP) or Copy Number Variation (CNV). Furthermore, epigenetic modifica...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/783592

    authors: Kang M,Kim DC,Liu C,Gao J

    更新日期:2015-01-01 00:00:00

  • Analysis of Self-Adhesive Resin Cement Microshear Bond Strength on Leucite-Reinforced Glass-Ceramic with/without Pure Silane Primer or Universal Adhesive Surface Treatment.

    abstract:OBJECTIVE:To evaluate the microshear bond strength (μSBS) of self-adhesive resin (SA) cement on leucite-reinforced glass-ceramic using silane or universal adhesive. MATERIALS AND METHODS:Ceramic blocks were etched with 9.5% hydrofluoric acid and divided into three groups (n = 16): (1) negative control (NC) without tre...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/361893

    authors: Lee Y,Kim JH,Woo JS,Yi YA,Hwang JY,Seo DG

    更新日期:2015-01-01 00:00:00

  • Performance study of chromium (VI) removal in presence of phenol in a continuous packed bed reactor by Escherichia coli isolated from East Calcutta Wetlands.

    abstract::Organic pollutants, like phenol, along with heavy metals, like chromium, are present in various industrial effluents that pose serious health hazard to humans. The present study looked at removal of chromium (VI) in presence of phenol in a counter-current continuous packed bed reactor packed with E. coli cells immobil...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/373412

    authors: Chakraborty B,Indra S,Hazra D,Betai R,Ray L,Basu S

    更新日期:2013-01-01 00:00:00

  • Yes-Associated Protein 1 as a Novel Prognostic Biomarker for Gastrointestinal Cancer: A Meta-Analysis.

    abstract:Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2018/4039173

    authors: Zhang L,Song X,Li X,Wu C,Jiang J

    更新日期:2018-11-14 00:00:00

  • Curcuma longa Is Able to Induce Apoptotic Cell Death of Pterygium-Derived Human Keratinocytes.

    abstract::Pterygium is a relatively common eye disease that can display an aggressive clinical behaviour. To evaluate the in vitro effects of Curcuma longa on human pterygium-derived keratinocytes, specimens of pterygium from 20 patients undergoing pterygium surgical excision were collected. Pterygium explants were put into cul...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2956597

    authors: Sancilio S,Di Staso S,Sebastiani S,Centurione L,Di Girolamo N,Ciancaglini M,Di Pietro R

    更新日期:2017-01-01 00:00:00

  • Vitamin B-6 Supplementation Could Mediate Antioxidant Capacity by Reducing Plasma Homocysteine Concentration in Patients with Hepatocellular Carcinoma after Tumor Resection.

    abstract::Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2016/7658981

    authors: Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

    更新日期:2016-01-01 00:00:00

  • Kinematic Validation of Postural Sway Measured by Biodex Biosway (Force Plate) and SWAY Balance (Accelerometer) Technology.

    abstract:Background:The Biodex Biosway® Balance System and SWAY Balance® Mobile smartphone application (SBMA) are portable instruments that assess balance function with force plate and accelerometer technology, respectively. The validity of these indirect clinical measures of postural sway merits investigation. Purpose:The pur...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/8185710

    authors: Dewan BM,Roger James C,Kumar NA,Sawyer SF

    更新日期:2019-12-21 00:00:00

  • Secretome Identifies Tenascin-X as a Potent Marker of Ovarian Cancer.

    abstract::CA-125 has been a valuable marker for the follow-up of ovarian cancer patients but it is not sensitive enough to be used as diagnostic marker. We had already used secretomic methods to identify proteins differentially secreted by serous ovarian cancer cells compared to healthy ovarian cells. Here, we evaluated the sec...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/208017

    authors: Kramer M,Pierredon S,Ribaux P,Tille JC,Petignat P,Cohen M

    更新日期:2015-01-01 00:00:00

  • Pandemic Avian Influenza and Intra/Interhaemagglutinin Subtype Electrostatic Variation among Viruses Isolated from Avian, Mammalian, and Human Hosts.

    abstract::Host jump can result in deadly pandemic events when avian influenza A viruses broaden their host specificity and become able to infect mammals, including humans. Haemagglutinin-the major capsid protein in influenza A viruses-is subjected to high rate mutations, of which several occur at its "head": the receptor-bindin...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/3870508

    authors: Righetto I,Filippini F

    更新日期:2018-05-17 00:00:00

  • Pegylated gold nanoparticles induce apoptosis in human chronic myeloid leukemia cells.

    abstract::Gold nanoparticles (AuNPs) have several potential biological applications as well as excellent biocompatibility. AuNPs with surface modification using polyethylene glycol (PEG-AuNPs) can facilitate easy conjugation with various biological molecules of interest. To examine the anticancer bioactivity of PEG-AuNPs, we in...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/182353

    authors: Huang YC,Yang YC,Yang KC,Shieh HR,Wang TY,Hwu Y,Chen YJ

    更新日期:2014-01-01 00:00:00

  • Biomedical applications of fermenticin HV6b isolated from Lactobacillus fermentum HV6b MTCC10770.

    abstract::Fermenticin HV6b is a class IIa antimicrobial peptide produced by Lactobacillus fermentum HV6b MTCC 10770 isolated from human vaginal ecosystem. It shows growth inhibition of a wide range of opportunistic pathogens of humans, for example, Bacteroides, Gardnerella vaginalis, Mobiluncus, Staphylococci, and Streptococci,...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/168438

    authors: Kaur B,Balgir PP,Mittu B,Kumar B,Garg N

    更新日期:2013-01-01 00:00:00

  • Acinetobacter baumannii Infection in Transfusion Dependent Thalassemia Patients with Sepsis.

    abstract:PURPOSE:To identify the Acinetobacter baumannii infection among transfusion dependent thalassemia patients. METHODS:A quantitative approach was employed to assess Acinetobacter baumannii infection in transfusion dependent thalassemia patients. Samples were collected from 916 patients, which have shown bacterial growth...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2351037

    authors: Abdul Rasheed M,Alzahrani FM,Sattar Shaikh S

    更新日期:2017-01-01 00:00:00

  • Gene profiling of bone around orthodontic mini-implants by RNA-sequencing analysis.

    abstract::This study aimed to evaluate the genes that were expressed in the healing bones around SLA-treated titanium orthodontic mini-implants in a beagle at early (1-week) and late (4-week) stages with RNA-sequencing (RNA-Seq). Samples from sites of surgical defects were used as controls. Total RNA was extracted from the tiss...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/538080

    authors: Nahm KY,Heo JS,Lee JH,Lee DY,Chung KR,Ahn HW,Kim SH

    更新日期:2015-01-01 00:00:00

  • Expression and complex formation of MMP9, MMP2, NGAL, and TIMP1 in porcine myocardium but not in skeletal muscles in male pigs with tachycardia-induced systolic heart failure.

    abstract::Matrix metalloproteinases (MMPs) are involved in the remodeling of extracellular matrix in various tissues. Their functioning could be related to the formation of complexes, containing MMP9, MMP2, tissue inhibitor of metalloproteinases type 1 (TIMP1), and neutrophil gelatinase-associated lipocalin (NGAL). Such complex...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/283856

    authors: Kiczak L,Tomaszek A,Bania J,Paslawska U,Zacharski M,Noszczyk-Nowak A,Janiszewski A,Skrzypczak P,Ardehali H,Jankowska EA,Ponikowski P

    更新日期:2013-01-01 00:00:00

  • Biomaterials-based modulation of the immune system.

    abstract::The immune system is traditionally considered from the perspective of defending against bacterial or viral infections. However, foreign materials like implants can also illicit immune responses. These immune responses are mediated by a large number of molecular signals, including cytokines, antibodies and reactive rad...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/732182

    authors: Gardner AB,Lee SK,Woods EC,Acharya AP

    更新日期:2013-01-01 00:00:00

  • Computed Tomography versus Optical Scanning: A Comparison of Different Methods of 3D Data Acquisition for Tooth Replication.

    abstract:Objectives:The study aimed to compare the accuracy of different methods of data acquisition and data reconstruction and to assess their usefulness for 3D printing of tooth replicas. Methods:3-dimensional models of molar and canine teeth obtain utilizing CBCT examination with different protocols, and optical scanning w...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/4985121

    authors: Kulczyk T,Rychlik M,Lorkiewicz-Muszyńska D,Abreu-Głowacka M,Czajka-Jakubowska A,Przystańska A

    更新日期:2019-04-10 00:00:00

  • Cilostazol Improves Proangiogenesis Functions in Human Early Endothelial Progenitor Cells through the Stromal Cell-Derived Factor System and Hybrid Therapy Provides a Synergistic Effect In Vivo.

    abstract::This study investigated the effect of cilostazol on proangiogenesis functions in human early endothelial progenitor cells (EPCs) in vitro and the therapeutic implication of hybrid therapy with cilostazol and human early EPCs in vivo. Cilostazol significantly increased colony-forming units and enhanced differentiation ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/3639868

    authors: Tseng SY,Chao TH,Li YH,Cho CL

    更新日期:2016-01-01 00:00:00

  • Impact of the 2009 (7th edition) AJCC melanoma staging system in the classification of thin cutaneous melanomas.

    abstract:CONTEXT:The 7th (2009) edition of the AJCC melanoma staging system incorporates tumor (Breslow) thickness, MR, and ulceration in stratifying T1 primary melanomas. Compared to the prior 6th (2001) edition, MR has replaced CL for thin melanomas. OBJECTIVE:We sought to identify and report differences of the classificatio...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/898719

    authors: Chu VH,Tetzlaff MT,Torres-Cabala CA,Prieto VG,Bassett R Jr,Gershenwald JE,McLemore MS,Ivan D,Wang WL,Ross MI,Curry JL

    更新日期:2013-01-01 00:00:00

  • Calcifying Matrix Vesicles and Atherosclerosis.

    abstract::Artery calcification is a well-recognized predictor of late atherosclerotic complications. In the intima media, calcification starts with apoptosis of vascular smooth muscle cells (VSMCs) and the release of calcifying matrix vesicles with diameter of 0.5-15 μm that can be observed microscopically. In complicated plaqu...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/7463590

    authors: Chistiakov DA,Myasoedova VA,Melnichenko AA,Grechko AV,Orekhov AN

    更新日期:2017-01-01 00:00:00

  • Fan-shaped complete block on helical tomotherapy for esophageal cancer: a phantom study.

    abstract::Radiation pneumonitis (RP) is a common complication for radiotherapy of esophageal cancer and is associated with the low dose irradiated lung volume. This study aims to reduce the mean lung dose (MLD) and the relative lung volume at 20 Gy (V 20) and at low dose region using various designs of the fan-shaped complete b...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/959504

    authors: Chang CH,Mok GS,Shueng PW,Yeh HP,Shiau AC,Tien HJ,Lin CT,Wu TH

    更新日期:2015-01-01 00:00:00

  • Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy.

    abstract::Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can b...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/6104738

    authors: Kang J,Fan W,Deng Q,He H,Huang F

    更新日期:2019-01-29 00:00:00

  • Breast cancer prognosis risk estimation using integrated gene expression and clinical data.

    abstract:BACKGROUND:Novel prognostic markers are needed so newly diagnosed breast cancer patients do not undergo any unnecessary therapy. Various microarray gene expression datasets based studies have generated gene signatures to predict the prognosis outcomes, while ignoring the large amount of information contained in establi...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/459203

    authors: Saini A,Hou J,Zhou W

    更新日期:2014-01-01 00:00:00