Pegylated gold nanoparticles induce apoptosis in human chronic myeloid leukemia cells.

abstract：Background:Left ventricular (LV) systolic dysfunction is common in septic shock. Global longitudinal strain (GLS) measured by speckle tracking echocardiography (STE) is a useful marker of intrinsic left ventricular systolic function. However, the association between left ventricular GLS and outcome in septic patients i...

journal_title：BioMed research international

authors： Hai PD,Binh NT,Hien NVQ,Hoang NH,Hoan VN,Son PN,Hoa LTV

更新日期：2020-10-21 00:00:00

abstract：:GABAergic inhibition and particularly perisomatic inhibition play a crucial role in controlling the firing properties of large principal cell populations. Furthermore, GABAergic network is a key element in the therapy attempting to reduce epileptic activity. Here, we present a review showing the synaptic changes of pe...

journal_title：BioMed research international

authors： Wittner L,Maglóczky Z

更新日期：2017-01-01 00:00:00

abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

journal_title：BioMed research international

authors： Kaur K,Kaur G

更新日期：2013-01-01 00:00:00

abstract：:GHK (glycyl-L-histidyl-L-lysine) is present in human plasma, saliva, and urine but declines with age. It is proposed that GHK functions as a complex with copper 2+ which accelerates wound healing and skin repair. GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity ...

journal_title：BioMed research international

authors： Pickart L,Vasquez-Soltero JM,Margolina A

更新日期：2015-01-01 00:00:00

abstract：:The occurrence of head and neck cancer (HNC) is associated with smoking and alcohol drinking. Tobacco smoking exposes smokers to a series of carcinogenic chemicals. Cytochrome P450 enzymes (CYP450s), such as CYP1A1, CYP1B1, and CYP2D6, usually metabolize carcinogens to their inactive derivatives, but they occasionally...

journal_title：BioMed research international

authors： Khlifi R,Messaoud O,Rebai A,Hamza-Chaffai A

更新日期：2013-01-01 00:00:00

abstract：:Toxoplasma gondii with worldwide distribution has received substantial medical and scientific attentions as it causes serious clinical and veterinary problems especially for pregnant women and immunocompromised patients. Heat shock protein 40 (HSP40) plays a variety of essential roles in the pathogenesis of this proto...

journal_title：BioMed research international

authors： Li ZY,Lu J,Zhou DH,Chen J,Zhu XQ

更新日期：2015-01-01 00:00:00

abstract：:Targeting nanoparticles by conjugating various specific ligands has shown potential therapeutic efficacy in nanomedicine. However, poor penetration of antitumor drugs into solid tumors remains a major obstacle. Here, we describe a targeting strategy for antitumor drug delivery by conjugating a crosslinked multilamella...

journal_title：BioMed research international

authors： Liu Y,Ji M,Wong MK,Joo KI,Wang P

更新日期：2013-01-01 00:00:00

abstract：:Little is known about the clinical value of the Hadlock and INTERGROWTH-21st EFW standards for predicting adverse perinatal outcomes (APOs) in the third trimester. The purpose of this study was to study the association between low estimated fetal weight percentile (EFWc) in the third trimester and the risk of APOs and...

journal_title：BioMed research international

authors： Zhu C,Ren YY,Wu JN,Zhou QJ

更新日期：2019-01-09 00:00:00

abstract：:Catalases are widely used in many scientific areas. A catalase gene (Kat) from Geobacillus sp. CHB1 encoding a monofunctional catalase was cloned and recombinant expressed in Escherichia coli (E. coli), which was the first time to clone and express this type of catalase of genus Geobacillus strains as far as we know. ...

journal_title：BioMed research international

authors： Jia X,Chen J,Lin C,Lin X

更新日期：2016-01-01 00:00:00

abstract：Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...

journal_title：BioMed research international

authors： Kartinah NT,Fadilah F,Ibrahim EI,Suryati Y

更新日期：2019-11-11 00:00:00

abstract：Background:Uveitis is a known ophthalmologic manifestation of seronegative spondyloarthropathy, including psoriatic arthritis. However, the data is less clear among patients with psoriasis due to the limited number of published studies. Aims:To investigate whether the risk of incident and prevalent uveitis is elevated...

journal_title：BioMed research international

authors： Chaiyabutr C,Ungprasert P,Silpa-Archa N,Wongpraparut C,Chularojanamontri L

更新日期：2020-07-15 00:00:00

abstract：:Objective. The purpose of this study was to (i) determine the cervical microbial composition in different abortion samples and to (ii) investigate the correlation between spontaneous abortion and cervical microbes in Korean women. Methods. We collected cervical swabs from women who had never undergone abortion (N = 36...

journal_title：BioMed research international

authors： Seo SS,Arokiyaraj S,Kim MK,Oh HY,Kwon M,Kong JS,Shin MK,Yu YL,Lee JK

更新日期：2017-01-01 00:00:00

abstract：:Aims. To compare the clinical features of endometrial polyps (EPs) between patients with endometriosis (EM) (EM group) and without EM (non-EM group). Methods and Results. Seventy-six cases in the EM group and 133 cases in the non-EM group underwent laparotomy or hysteroscopy and laparoscopy; later, it was confirmed th...

journal_title：BioMed research international

authors： Wang N,Zhang Y,Liu B

更新日期：2016-01-01 00:00:00

abstract：Objective:ANGPTL7 is a member of the angiogenin-like protein family. Compared to other members, ANGPTL7 is the least known. Recent studies have explored the relationship between ANGPTL7 and multiple pathological processes and diseases. However, there is no research about ANGPTL7 in neonates. This study was designed to ...

journal_title：BioMed research international

authors： Xia X,Ren Z,Yan L,Zheng X,Yang H,Kang M,Yan H,Zhong Z,Xu F,Miao J,Wang J,Li Y,Wei W,Yang J

更新日期：2020-11-27 00:00:00

abstract：:Myofascial pain syndrome is characterized by pain and a limited range of joint motion caused by muscle contracture related to motor-end-plate dysfunction and the presence of myofascial trigger points (MTrPs). It is the most frequent cause of musculoskeletal pain, with a worldwide prevalence varying between 13.7% and 4...

journal_title：BioMed research international

authors： Wada JT,Akamatsu F,Hojaij F,Itezerote A,Scarpa JC,Andrade M,Jacomo A

更新日期：2020-01-22 00:00:00

abstract：Background:Acute myocardial infarction (AMI) is regarded as an urgent clinical entity, and identification of differentially expressed genes, lncRNAs, and altered pathways shall provide new insight into the molecular mechanisms behind AMI. Materials and Methods:Microarray data was collected to identify key genes and ln...

journal_title：BioMed research international

authors： Sheng X,Fan T,Jin X

更新日期：2020-10-06 00:00:00

abstract：:Mesenchymal stem cells (MSCs) therapy has been applied to a wide range of diseases with excessive immune response, including inflammatory bowel disease (IBD), owing to its powerful immunosuppression and its ability to repair tissue lesions. Different sources of MSCs show different therapeutic properties. Engineering m...

journal_title：BioMed research international

authors： Kang J,Zhang L,Luo X,Ma X,Wang G,Yang Y,Yan Y,Qian H,Zhang X,Xu W,Mao F

更新日期：2018-12-26 00:00:00

abstract：OBJECTIVE:Radiopharmaceutical production process must adhere to current good manufacturing process (CGMP) compliance to ensure the quality of precursor, prodrug (active pharmaceutical ingredient, API), and the final drug product that meet acceptance criteria. We aimed to develop an automated system for production of CG...

journal_title：BioMed research international

authors： Chi YT,Chu PC,Chao HY,Shieh WC,Chen CC

更新日期：2014-01-01 00:00:00

abstract：:Taiwan has very high incidence and prevalence of chronic kidney disease (CKD), which easily progresses to end-stage renal disease (ESRD). The association between inflammation and CKD has been explored in several studies. ORAI1 functions as a pore-forming subunit of the store-operated calcium channels which are involve...

journal_title：BioMed research international

authors： Hwang DY,Chien SC,Hsu YW,Kao CC,Cheng SY,Lu HC,Wu MS,Chang JM

更新日期：2014-01-01 00:00:00

abstract：Objective:Mounting evidence has elaborated the implication of long noncoding RNAs (lncRNAs) in tumorigenesis of several cancers, including glioma. However, little was known about the mechanism of lncRNA maternally expressed gene 3 (MEG3) in the development and progression of glioma. This work is designed to explore the...

journal_title：BioMed research international

authors： Gong X,Huang MY

更新日期：2020-01-11 00:00:00

abstract：:Recently, an important topic of the acquired immunodeficiency syndrome (AIDS) had been published in 2013. In this report, the expression of the IFN-induced myxovirus resistance 2 (MX2) had been defined the function to kill the human immunodeficiency virus (HIV). The screening from the Traditional Chinese Medicine (TCM...

journal_title：BioMed research international

authors： Hung TC,Lee WY,Chen KB,Chan YC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:Bayesian analysis was used to estimate the pig's and herd's true prevalence of enteropathogenic Yersinia in serum samples collected from Finnish pig farms. The sensitivity and specificity of the diagnostic test were also estimated for the commercially available ELISA which is used for antibody detection against entero...

journal_title：BioMed research international

authors： Vilar MJ,Ranta J,Virtanen S,Korkeala H

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to evaluate, at a laboratory scale, the ability of this microorganism to grow in seawater and bioaccumulate in mussels (Mytilus galloprovincialis) maintained in constantly aerated tanks, containing twenty litres of artificial seawater. Three concentrations of A. butzleri LMG 10828(T) were tes...

journal_title：BioMed research international

authors： Ottaviani D,Chierichetti S,Rocchegiani E,Bartolini C,Masini L,Santarelli S,Leoni F

更新日期：2013-01-01 00:00:00

abstract：:Hypoxia plays an essential role in orchestrating Epithelial-mesenchymal transition and promoting metastasis of colorectal cancer. However, the underlying mechanisms are still not well elucidated. Here, we present that hypoxic exposure causes endoplasmic reticulum stress and activates the unfolded protein response path...

journal_title：BioMed research international

authors： Zheng H,Wu Y,Guo T,Liu F,Xu Y,Cai S

更新日期：2020-01-27 00:00:00

abstract：:The biological age (BA) equation is a prediction model that utilizes an algorithm to combine various biological markers of ageing. Different from traditional concepts, the BA equation does not emphasize the importance of a golden index but focuses on using indices of vital organs to represent the senescence of whole b...

journal_title：BioMed research international

authors： Jia L,Zhang W,Jia R,Zhang H,Chen X

更新日期：2016-01-01 00:00:00

abstract：:Progression of idiopathic dilated cardiomyopathy (IDCM) is marked with extensive left ventricular remodeling whose clinical manifestations and molecular basis are poorly understood. We aimed to evaluate the clinical potential of titin ligands in monitoring progression of cardiac remodeling associated with end-stage ID...

journal_title：BioMed research international

authors： Bogomolovas J,Brohm K,Čelutkienė J,Balčiūnaitė G,Bironaitė D,Bukelskienė V,Daunoravičus D,Witt CC,Fielitz J,Grabauskienė V,Labeit S

更新日期：2015-01-01 00:00:00

abstract：:The classic assay for a large population biomass is time-consuming, labor intensive, and chemically expensive. This paper would find out a rapid assay for predicting biomass digestibility from biomass structural features without hydrolysis. We examined the 62 representative corn stover accessions that displayed a dive...

journal_title：BioMed research international

authors： Gao L,Chen S,Zhang D

更新日期：2018-08-12 00:00:00

abstract：:Aim. This study aimed to evaluate the reliability of 3D-TMT, previously used only for dynamic testing, in a static cephalometric evaluation. Material and Method. A group of 40 patients (20 males and 20 females; mean age 14.2 ± 1.2 years; 12-18 years old) was included in the study. The measurements obtained by the 3D-T...

journal_title：BioMed research international

authors： Mummolo S,Nota A,Marchetti E,Padricelli G,Marzo G

更新日期：2016-01-01 00:00:00

abstract：:Sericin is a natural protein component of silks of silkworm and has potential utility in multiple areas such as pharmacological, cosmetics, and biotechnological industries. However, the understanding of its toxicological safety is still limited. This study evaluated the safety of water-extract sericin from silkworm (B...

journal_title：BioMed research international

authors： Qin H,Zhang J,Yang H,Yao S,He L,Liang H,Wang Y,Chen H,Zhao P,Qin G

更新日期：2020-11-05 00:00:00

abstract：:The aim of this study is to investigate the changes in QT, QTc, and Tp-e intervals and Tp-e/QT ratio on surface electrocardiogram (ECG) signals during anaesthesia induction using propofol or sevoflurane after preoperative cefuroxime infusion. Some 120 cases of gynaecological patients are randomly divided into propofol...

journal_title：BioMed research international

authors： Liu Y,Gao H,Wang G,An L,Yi J,Fu X,Wen C,Wang Z

更新日期：2019-01-02 00:00:00