Cloning, Expression, and Characterization of a Novel Thermophilic Monofunctional Catalase from Geobacillus sp. CHB1.

abstract：:Gastric cancer is one of the most common cancers and the efficient therapeutic methods are limited. Further study of the exact molecular mechanism of gastric cancer to develop novel targeted therapies is necessary and urgent. We herein systematically examined that miR-204 suppressed both proliferation and metastasis o...

journal_title：BioMed research international

authors： Yuan X,Wang S,Liu M,Lu Z,Zhan Y,Wang W,Xu AM

更新日期：2017-01-01 00:00:00

abstract：:Caudal epidural block is a commonly used technique for surgical anesthesia in children and chronic pain management in adults. It is performed by inserting a needle through the sacral hiatus to gain entrance into the sacral epidural space. Using conventional blind technique, the failure rate of caudal epidural block in...

journal_title：BioMed research international

authors： Kao SC,Lin CS

更新日期：2017-01-01 00:00:00

abstract：:Human plasma is an aqueous solution that has to abide by chemical rules such as the principle of electrical neutrality and the constancy of the ionic product for water. These rules define the acid-base balance in the human body. According to the electroneutrality principle, plasma has to be electrically neutral and th...

journal_title：BioMed research international

authors： Adeva-Andany MM,Carneiro-Freire N,Donapetry-García C,Rañal-Muíño E,López-Pereiro Y

更新日期：2014-01-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy, is characterized by muscular wasting caused by dystrophin deficiency that ultimately ends in force reduction and premature death. In addition to primary genetic defect, several mechanisms contribute to DMD pathogenesis. Recently, antioxidan...

journal_title：BioMed research international

authors： Sitzia C,Farini A,Colleoni F,Fortunato F,Razini P,Erratico S,Tavelli A,Fabrizi F,Belicchi M,Meregalli M,Comi G,Torrente Y

更新日期：2015-01-01 00:00:00

abstract：:Heat shock proteins 70 and heat shock proteins 90 (Hsp70/90) have been implicated in many crucial steps of carcinogenesis: stabilizing oncogenic proteins, inhibiting programmed cell death and replicative senescence, induction of tumor angiogenesis, and activation of the invasion and metastasis. Plenty of cancer relate...

journal_title：BioMed research international

authors： Wang H,Tan MS,Lu RC,Yu JT,Tan L

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Maternal thyroid dysfunction in early pregnancy may increase the risk of adverse pregnancy complications and neurocognitive deficiencies in the developing fetus. Currently, some researchers demonstrated that body mass index (BMI) is associated with thyroid function in nonpregnant population. Hence, the Ameri...

journal_title：BioMed research international

authors： Han C,Li C,Mao J,Wang W,Xie X,Zhou W,Li C,Xu B,Bi L,Meng T,Du J,Zhang S,Gao Z,Zhang X,Yang L,Fan C,Teng W,Shan Z

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. AIMS:To develop a metabolic syndrome rat model by induction of fructose drinking water (FDW) in male Wistar rats. METHODS:Eighteen male Wistar rats were fed with FDW 20%...

journal_title：BioMed research international

authors： Mamikutty N,Thent ZC,Sapri SR,Sahruddin NN,Mohd Yusof MR,Haji Suhaimi F

更新日期：2014-01-01 00:00:00

abstract：:This paper presents different applications, in various foodstuffs, by a novel electronic nose (EN) based on a mixed metal oxide sensors array composed of thin films as well as nanowires. The electronic nose used for this work has been done, starting from the commercial model EOS835 produced by SACMI Scarl. The SENSOR ...

journal_title：BioMed research international

authors： Sberveglieri V,Carmona EN,Comini E,Ponzoni A,Zappa D,Pirrotta O,Pulvirenti A

更新日期：2014-01-01 00:00:00

abstract：:Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease, which manifests as a succession of outbreaks. OLP was associated with salivary oxidative stress. Randomized, double blind, parallel-group study was performed. The sample consisted of 55 clinically and histopathologically diagnosed OLP patients. ...

journal_title：BioMed research international

authors： Tvarijonaviciute A,Aznar-Cayuela C,Rubio CP,Tecles F,Ceron JJ,López-Jornet P

更新日期：2018-05-27 00:00:00

abstract：:Although cases of Mediterranean spotted fever (MSF) have been reported for decades in southeastern Romania, there are few published data. We retrospectively studied 339 patients, diagnosed with MSF at the National Institute of Infectious Diseases "Prof. Dr. Matei Bals" between 2000 and 2011, in order to raise awarenes...

journal_title：BioMed research international

authors： Pitigoi D,Olaru ID,Badescu D,Rafila A,Arama V,Hristea A

更新日期：2013-01-01 00:00:00

abstract：:The acute toxicity, the antioxidant activity, and the pharmacological activity on the gastrointestinal tract of rodents of the ethanolic extract (TFEE) from the bark of Terminalia fagifolia Mart. & Zucc. (Combretaceae) and of its aqueous (TFAqF), hydroalcoholic (TFHAF), and hexanic (TFHEXF) partition fractions have be...

journal_title：BioMed research international

authors： Nunes PH,Martins Mdo C,Oliveira Rde C,Chaves MH,Sousa EA,Leite JR,Véras LM,Almeida FR

更新日期：2014-01-01 00:00:00

abstract：:We have developed a new "drug" and approach that appear to be effective in reducing arterial age. This "drug" represents a low, subtherapeutic dose of statin and sartan and particularly their low-dose combination. The improvement of arterial wall characteristics, also reflecting in a decrease of arterial age, was achi...

journal_title：BioMed research international

authors： Janić M,Lunder M,Šabovič M

更新日期：2015-01-01 00:00:00

abstract：:Heart disease is the leading cause of death worldwide. Therefore, assessing the risk of its occurrence is a crucial step in predicting serious cardiac events. Identifying heart disease risk factors and tracking their progression is a preliminary step in heart disease risk assessment. A large number of studies have rep...

journal_title：BioMed research international

authors： Jonnagaddala J,Liaw ST,Ray P,Kumar M,Dai HJ,Hsu CY

更新日期：2015-01-01 00:00:00

abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

journal_title：BioMed research international

authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

更新日期：2015-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs and polymorphisms in ...

journal_title：BioMed research international

authors： García-Bermúdez M,López-Mejías R,Genre F,Castañeda S,Corrales A,Llorca J,González-Juanatey C,Ubilla B,Miranda-Filloy JA,Pina T,Gómez-Vaquero C,Rodríguez-Rodríguez L,Fernández-Gutiérrez B,Balsa A,Pascual-Salcedo D,López-Long

更新日期：2015-01-01 00:00:00

abstract：Background:Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies. Considering the recent increase in the prevalence of the family virus and its risk potential, we investigated the codon usage pattern to understand its evolutionar...

journal_title：BioMed research international

authors： Yao H,Chen M,Tang Z

更新日期：2019-06-27 00:00:00

abstract：:Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibact...

journal_title：BioMed research international

authors： Bogacz M,Morawiec T,Śmieszek-Wilczewska J,Janowska-Bogacz K,Bubiłek-Bogacz A,Rój R,Pinocy K,Mertas A

更新日期：2019-10-07 00:00:00

abstract：:In orthopaedic surgery and sports medicine, the knee joint has traditionally been considered the workhorse. The reconstruction of every damaged element in this joint is crucial in achieving the surgeon's goal to restore the knee function and prevent degeneration towards osteoarthritis. In the last fifteen years, the f...

journal_title：BioMed research international

authors： Sánchez M,Delgado D,Sánchez P,Fiz N,Azofra J,Orive G,Anitua E,Padilla S

更新日期：2014-01-01 00:00:00

abstract：Objectives:The mortality rate of patients with acute respiratory distress syndrome (ARDS) is high. Hence, it is crucial to identify a reliable biomarker with wide clinical applications for predicting the prognosis of patients with ARDS. This systematic review and meta-analysis was conducted to investigate the value of ...

journal_title：BioMed research international

authors： Ni Q,Li C,Lin H

更新日期：2020-04-05 00:00:00

abstract：:The goal of the present study were (1) to investigate the pathological characteristics of gastrocnemius muscle (GM) and quantitatively assess GM tissue stiffness in rat models with spinal cord injury (SCI) and (2) to explore the correlation between pathological characteristics changes and Young's modulus value of GM. ...

journal_title：BioMed research international

authors： Jiang L,Wang YJ,Wang QY,Wang Q,Wei XM,Li N,Guo WP,Dou ZL

更新日期：2017-01-01 00:00:00

abstract：:The most frequently seen types of tremor are essential (ET) and parkinsonian tremor (PT) and in some patients clinical characteristics of these tremor types overlap. It is vital to distinguish between these two types of tremor in order to reach the right diagnosis and select the appropriate treatment. One of the widel...

journal_title：BioMed research international

authors： Kragelj V,Georgiev D,Pirtošek Z,Ribarič S

更新日期：2014-01-01 00:00:00

abstract：:This study was aimed at investigating the changes in the degree of weight support loaded on the cane and paretic-side lower limb muscle activation according to the types of cane and cane-supported gait using a weight-support feedback cane (WSFC). Eleven hemiparetic stroke patients were recruited from a local rehabilit...

journal_title：BioMed research international

authors： Choi EP,Yang SJ,Jung AH,Na HS,Kim YO,Cho KH

更新日期：2020-09-23 00:00:00

abstract：:A role of pro- and antioxidants for reducing rectal cancer (RC) incidence in operative, preoperative, and postoperative treatments is still disputable and controversial. The redox state of venous blood and tissues of blood vessels of 60 patients with RC (T2-4N0-2M0G2) and 20 donors is studied by means of the conventio...

journal_title：BioMed research international

authors： Burlaka AP,Vovk AV,Burlaka AA,Gafurov MR,Iskhakova KB,Lukin SN

更新日期：2018-08-13 00:00:00

abstract：:The normal physiological loads from muscles experienced by the spine are largely unknown due to a lack of data. The aim of this study is to investigate the effects of varying muscle directions on the outcomes predicted from finite element models of human lumbar spine. A nonlinear finite element model of L3-L5 was empl...

journal_title：BioMed research international

authors： Zhu R,Niu WX,Wang ZP,Pei XL,He B,Zeng ZL,Cheng LM

更新日期：2018-01-03 00:00:00

abstract：:Schistosomiasis is one of the world's major public health problems. Praziquantel is currently the only effective drug against schistosomiasis. As resistance of praziquantel has emerged in some endemic areas, development of new antischistosomal agents should be a high priority. In this study, a phage display peptide li...

journal_title：BioMed research international

authors： Song LJ,Li JH,Yin XR,Zhang W,Jin Y,Gao H,Wang J,Yu CX,Hua ZC

更新日期：2018-06-05 00:00:00

abstract：:The differential effects of a selective kappa- (κ-) opioid receptor agonist, U50488, were elucidated by monitoring the contraction of isolated guinea pig atrial and ventricular muscles. In electrically driven left atria, U50488 in nanomolar concentration range decreased the contractile force. Norbinaltorphimine (norBN...

journal_title：BioMed research international

authors： Hung CF,Li HJ,Chang HH,Lee GA,Su MJ

更新日期：2015-01-01 00:00:00

abstract：:Objective. Duodenal atresia (DA) routinely has been corrected by laparotomy and duodenoduodenostomy with excellent long-term results. We revisited the patients with DA treated in the last 12 years (2004-2016) comparing the open and the minimally invasive surgical (MIS) approach. Methods. We divided our cohort of patie...

journal_title：BioMed research international

authors： Chiarenza SF,Bucci V,Conighi ML,Zolpi E,Costa L,Fasoli L,Bleve C

更新日期：2017-01-01 00:00:00

abstract：:This study applies the environmental Kuznets curve to test the relationship between the regional economic growth and the different types of agricultural nonpoint source pollution loads in the Ningxia Yellow River irrigation area by using the Johnes export coefficient method. Results show that the pollution load genera...

journal_title：BioMed research international

authors： Mao C,Zhai N,Yang J,Feng Y,Cao Y,Han X,Ren G,Yang G,Meng QX

更新日期：2013-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a central nervous system (CNS) disease resulting from a targeted autoimmune-mediated attack on myelin proteins in the CNS. The release of Th1 inflammatory mediators in the CNS activates macrophages, antibodies, and microglia resulting in myelin damage and the induction of neuropathic pain (N...

journal_title：BioMed research international

authors： Zhu W,Acosta C,MacNeil B,Cortes C,Intrater H,Gong Y,Namaka M

更新日期：2013-01-01 00:00:00

abstract：:There is mounting evidence that burnout is a risk factor for cardiovascular disease (CVD). Stress-related dysregulation of the sympathetic and parasympathetic system and the hypothalamic pituitary adrenal (HPA) axis may explain the enhanced risk for CVD. To test this hypothesis, 55 patients (34 males and 21 females) w...

journal_title：BioMed research international

authors： de Vente W,van Amsterdam JG,Olff M,Kamphuis JH,Emmelkamp PM

更新日期：2015-01-01 00:00:00