High Body Mass Index Is an Indicator of Maternal Hypothyroidism, Hypothyroxinemia, and Thyroid-Peroxidase Antibody Positivity during Early Pregnancy.

abstract：BACKGROUND:Cancer/testis antigens (CTAs) are ideal targets for cancer immunotherapy in virtue of their restricted expression profile in normal tissues. However, CTA-targeted immunotherapy has been rather disappointing clinical setting for CTAs are downregulated by cytosine-phosphate-guanosine (CpG) methylation in their...

journal_title：BioMed research international

authors： Sun JZ,Gao L,Gao L,Wang W,Du N,Yang J,Wan L,Liu F,Wang LL,Yu L

更新日期：2013-01-01 00:00:00

abstract：:Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...

journal_title：BioMed research international

authors： Wen J,Yin P,Li L,Kang G,Ning G,Cao Y,Gao F,Su Y,Wu Y,Zhang X

更新日期：2020-04-15 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) patients often develop bone metastases (BM), and the overall survival for these patients is usually perishing. However, a model with high accuracy for predicting the survival of NSCLC with BM is still lacking. Here, we aimed to establish a model based on artificial intelligence for p...

journal_title：BioMed research international

authors： Huang Z,Hu C,Chi C,Jiang Z,Tong Y,Zhao C

更新日期：2020-06-27 00:00:00

abstract：:Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmis...

journal_title：BioMed research international

authors： Reis Machado J,da Silva MV,Cavellani CL,dos Reis MA,Monteiro ML,Teixeira Vde P,Miranda Corrêa RR

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...

journal_title：BioMed research international

authors： Deylam Salehi M,Ferdosi-Shahandashti E,Yahyapour Y,Khafri S,Pournajaf A,Rajabnia R

更新日期：2017-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder with two hallmarks: β-amyloid plagues and neurofibrillary tangles. It is one of the most alarming illnesses to elderly people. No effective drugs and therapies have been developed, while mechanism-based explorations of therapeutic approaches have bee...

journal_title：BioMed research international

authors： Jia Q,Deng Y,Qing H

更新日期：2014-01-01 00:00:00

abstract：:A metabolic disorder is considered one of the hallmarks of cancer. Multiple differentially expressed metabolic genes have been identified in colon cancer (CC), and their biological functions and prognostic values have been well explored. The purpose of the present study was to establish a metabolic signature to optimi...

journal_title：BioMed research international

authors： Luo D,Shan Z,Liu Q,Cai S,Li Q,Li X

更新日期：2020-11-17 00:00:00

abstract：:Effects of in ovo injection of Q10 on hatchability, performance (feed intake (FI), body weight gain (BWG), feed/gain ratio (F/G)) traits, and immune status of Ross × Ross 308 broiler chicks, hatched from eggs laid by a 38-week-old breeder flock, were determined through 42 days after hatch. Eggs containing live embryos...

journal_title：BioMed research international

authors： Kalantar M,Hosseini SM,Hosseini MR,Kalantar MH,Farmanullah,Yang LG

更新日期：2019-02-04 00:00:00

abstract：BACKGROUND AND AIM:The sensitivity and specificity of biomarkers used for predicting peripheral neuropathy in patients with systemic lupus erythematosus (SLE) and nephritis (SLE-LN) remain unsatisfactory. This study aimed to determine the autoantibodies levels in SLE-LN patients with peripheral neuropathy. METHODS:Dat...

journal_title：BioMed research international

authors： Su YJ,Huang CR,Chang WN,Tsai NW,Kung CT,Lin WC,Huang CC,Su CM,Cheng BC,Chang YT,Lu CH

更新日期：2014-01-01 00:00:00

abstract：:Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF). Hitherto, the development of consistent, stable, and reproducible models of closed-chest MI in large animals, ...

journal_title：BioMed research international

authors： Biondi-Zoccai G,De Falco E,Peruzzi M,Cavarretta E,Mancone M,Leoni O,Caristo ME,Lotrionte M,Marullo AG,Amodeo A,Pacini L,Calogero A,Petrozza V,Chimenti I,D'Ascenzo F,Frati G

更新日期：2013-01-01 00:00:00

abstract：:This study described a TaqMan based real-time fluorescent quantitative PCR (qPCR) method to detect porcine cytomegalovirus (PCMV) infection, targeting the conserved region of the DNA polymerase (DPOL) gene. The standard curve showed a linear regression relationship with a coefficient of 0.999 and a slope of y = -3.249...

journal_title：BioMed research international

authors： Chen R,Chen Q,Wu X,Che Y,Wang C,Wang L,Yan S,Zhou L

更新日期：2020-01-10 00:00:00

abstract：:Mexico has one of the highest incidences of childhood leukemia worldwide and significantly higher mortality rates for this disease compared with other countries. One possible cause is the high prevalence of gene rearrangements associated with the etiology or with a poor prognosis of childhood acute lymphoblastic leuke...

journal_title：BioMed research international

authors： Bekker-Méndez VC,Miranda-Peralta E,Núñez-Enríquez JC,Olarte-Carrillo I,Guerra-Castillo FX,Pompa-Mera EN,Ocaña-Mondragón A,Rangel-López A,Bernáldez-Ríos R,Medina-Sanson A,Jiménez-Hernández E,Amador-Sánchez R,Peñaloza-González JG,

更新日期：2014-01-01 00:00:00

abstract：:The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk of developing PD in certa...

journal_title：BioMed research international

authors： Gopalai AA,Lim SY,Chua JY,Tey S,Lim TT,Mohamed Ibrahim N,Tan AH,Eow GB,Abdul Aziz Z,Puvanarajah SD,Viswanathan S,Looi I,Lim SK,Tan LP,Chong YB,Tan CT,Zhao Y,Tan EK,Ahmad-Annuar A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:We aimed to identify certain genes related to response to infliximab (IFX) and biomarkers to predict the IFX effect for Japanese Crohn's disease (CD) patients by performing an association study of single nucleotide polymorphisms (SNPs) in candidate genes in the interleukin- (IL-) 17 signaling pathway with re...

journal_title：BioMed research international

authors： Urabe S,Isomoto H,Ishida T,Maeda K,Inamine T,Kondo S,Higuchi N,Sato K,Uehara R,Yajima H,Machida H,Chen CC,Fukuda Y,Takeshima F,Nakao K,Tsukamoto K

更新日期：2015-01-01 00:00:00

abstract：:Nutrient overload leads to impaired muscle oxidative capacity and insulin sensitivity. However, comparative analyses of the effects of dietary manipulation on skeletal muscles with different fiber composition are lacking. This study aimed to investigate the selective adaptations in the soleus and tibialis anterior mus...

journal_title：BioMed research international

authors： Collino M,Mastrocola R,Nigro D,Chiazza F,Aragno M,D'Antona G,Minetto MA

更新日期：2014-01-01 00:00:00

abstract：:This study aims to investigate the expression of macrophage inflammatory protein-3 alpha (MIP-3α) and cystatin A in nasopharyngeal carcinoma (NPC) and their association with clinical characteristics and prognosis. Primary tumor specimens from 114 NPC patients and associated clinical follow-up data were collected, and ...

journal_title：BioMed research international

authors： Tang M,Ou N,Li C,Lu A,Li J,Ma L,Zhong W,Gao J,Zheng Y,Cai Y

更新日期：2015-01-01 00:00:00

abstract：:Light traps represent the most used attractive system to collect and monitor phlebotomine sand flies. Recent studies have suggested that light traps can be easily upgraded by the use of light-emitting diode (LED) with positive effects on trap design, weight, and battery life. However, scant data on the effect of diffe...

journal_title：BioMed research international

authors： Gaglio G,Napoli E,Arfuso F,Abbate JM,Giannetto S,Brianti E

更新日期：2018-06-27 00:00:00

abstract：:Epithelial Cl(-) secretion plays important roles in water secretion preventing bacterial/viral infection and regulation of body fluid. We previously suggested that quercetin would be a useful compound for maintaining epithelial Cl(-) secretion at a moderate level irrespective of cAMP-induced stimulation. However, we n...

journal_title：BioMed research international

authors： Sun H,Niisato N,Nishio K,Hamilton KL,Marunaka Y

更新日期：2014-01-01 00:00:00

abstract：:Natural enzyme mimics have attracted considerable attention due to leakage of enzymes and their easy denaturation during their storage and immobilization procedure. Here in this study, for the first time, a new iron oxide hydroxide, ferrihydrite - Fe1.44O0.32 (OH) 3.68 magnetic nanoparticles were synthesized by bacter...

journal_title：BioMed research international

authors： Ahmed A,Abagana A,Cui D,Zhao M

更新日期：2019-03-28 00:00:00

abstract：:This study was conducted to determine the effects of feeding oil palm frond silage based diets with added linseed oil (LO) containing high α -linolenic acid (C18:3n-3), namely, high LO (HLO), low LO (LLO), and without LO as the control group (CON) on the fatty acid (FA) composition of subcutaneous adipose tissue and t...

journal_title：BioMed research international

authors： Ebrahimi M,Rajion MA,Goh YM,Sazili AQ,Schonewille JT

更新日期：2013-01-01 00:00:00

abstract：:Non-VKA oral anticoagulants (NOACs) have now widely reached the lucrative market of anticoagulation. While the marketing authorization holders claimed that no routine monitoring is required and that these compounds can be given at fixed doses, several evidences arisen from the literature tend to demonstrate the opposi...

journal_title：BioMed research international

authors： Douxfils J,Mani H,Minet V,Devalet B,Chatelain B,Dogné JM,Mullier F

更新日期：2015-01-01 00:00:00

abstract：:Medicinal plants have played an important role in the treatment of many diseases. Medicinal plants are believed to be well appropriate with the human body and to produce less side influences than the pharmaceuticals. Kingdom of Saudi Arabia has abundant and wide variety of medicinal plants whose therapeutic effects ha...

journal_title：BioMed research international

authors： Almalki DA,Alghamdi SA,Al-Attar AM

更新日期：2019-02-27 00:00:00

abstract：:The anaerobic batch test (45 days at 37°C) was performed to describe the effect of thermal pretreatment at moderate temperatures (60, 80, and 100°C) over durations of 10 and 20 minutes on the enhancement of biogas production using hotel food waste from city of Jaipur, India. The results showed that the total cumulativ...

journal_title：BioMed research international

authors： Gandhi P,Paritosh K,Pareek N,Mathur S,Lizasoain J,Gronauer A,Bauer A,Vivekanand V

更新日期：2018-09-16 00:00:00

abstract：Objective:To investigate the effects of electroacupuncture (EA) at "Zusanli" (ST36) and "Shangjuxu"(ST37) on reducing inflammatory reaction and improving intestinal dysfunction in patients with sepsis-induced intestinal dysfunction with syndrome of obstruction of the bowels Qi. Methods:A total of 71 patients with seps...

journal_title：BioMed research international

authors： Meng JB,Jiao YN,Zhang G,Xu XJ,Ji CL,Hu MH,Lai ZZ,Zhang M

更新日期：2018-06-26 00:00:00

abstract：:Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...

journal_title：BioMed research international

authors： Cui Y,Cai M,Stanley HE

更新日期：2017-01-01 00:00:00

abstract：:This study examines the isoform-specific effects of short-term hindlimb suspension (HS) on the Na,K-ATPase in rat soleus muscle. Rats were exposed to 24-72 h of HS and we analyzed the consequences on soleus muscle mass and contractile parameters; excitability and the resting membrane potential (RMP) of muscle fibers; ...

journal_title：BioMed research international

authors： Kravtsova VV,Matchkov VV,Bouzinova EV,Vasiliev AN,Razgovorova IA,Heiny JA,Krivoi II

更新日期：2015-01-01 00:00:00

abstract：:Pterospartum tridentatum and Mentha pulegium are largely used in Portuguese folk medicine to treat several human disorders and inflammatory processes but without any consistent evidence for those beneficial pointed properties. Thus, the aim of the current work is to evaluate its benefits and phytochemicals related to ...

journal_title：BioMed research international

authors： Aires A,Marrinhas E,Carvalho R,Dias C,Saavedra MJ

更新日期：2016-01-01 00:00:00

abstract：Objectives:Percutaneous coronary intervention (PCI) is the mainstay treatment for coronary artery disease but complications such as in-stent restenosis and thrombosis remain problematic. Radiofrequency balloon angioplasty (RBA) can improve lumen dimension, fusing intimal tears, and artery dissection but is associated w...

journal_title：BioMed research international

authors： Chen Q,Wang M,Shao S,Liu H,Xia X,Tse G,Yuan M,Zhang Y,Liang X,Liu T,Li G

更新日期：2018-12-23 00:00:00

abstract：:Body weight supported locomotor training uses neuroplasticity principles to improve recovery following a spinal cord injury (SCI). Steady state locomotion using the same body weight support (BWS) percent was compared in 7 males (42.6 ± 4.29 years) with incomplete SCI and matched (gender, age) noninjured controls (42.7...

journal_title：BioMed research international

authors： Fenuta AM,Hicks AL

更新日期：2014-01-01 00:00:00

abstract：:Enzymes play important roles in most of the biological processes. Although only a small fraction of residues are directly involved in catalytic reactions, these catalytic residues are the most crucial parts in enzymes. The study of the fundamental and unique features of catalytic residues benefits the understanding of...

journal_title：BioMed research international

authors： Chien YT,Huang SW

更新日期：2013-01-01 00:00:00