Histological and Pathological Assessment of miR-204 and SOX4 Levels in Gastric Cancer Patients.

abstract：:Several lines of evidence indicate that amyloid β (Aβ), particularly Aβ oligomers (AβOs), plays a causative role in Alzheimer's disease. However, the mechanisms underlying the action of an anti-AβO antibody to clarify the toxic action of AβOs remain elusive. Here, we showed that the anti-AβO antibody (monoclonal 72D9)...

journal_title：BioMed research international

authors： Matsubara E,Takamura A,Okamoto Y,Oono H,Nakata T,Wakasaya Y,Kawarabayashi T,Shoji M

更新日期：2013-01-01 00:00:00

abstract：:As the heart transitions from one exercise intensity to another, changes in cardiac output occur, which are modulated by alterations in force development and calcium handling. Although the steady-state force-calcium relationship at various heart rates is well investigated, regulation of these processes during transiti...

journal_title：BioMed research international

authors： Haizlip KM,Milani-Nejad N,Brunello L,Varian KD,Slabaugh JL,Walton SD,Gyorke S,Davis JP,Biesiadecki BJ,Janssen PM

更新日期：2015-01-01 00:00:00

abstract：:Besides the pinpointing of individual disease-related genes, associating protein complexes to human inherited diseases is also of great importance, because a biological function usually arises from the cooperative behaviour of multiple proteins in a protein complex. Moreover, knowledge about disease-related protein co...

journal_title：BioMed research international

authors： Jacquemin T,Jiang R

更新日期：2013-01-01 00:00:00

abstract：:Effective alteration of the recalcitrance properties like crystallization of cellulose, lignin shield, and interlinking of lignocellulosic biomass is an ideal way to utilize the full-scale potential for biofuel production. This study exhibited three different pretreatment effects to enhance the digestibility of corn s...

journal_title：BioMed research international

authors： Siddhu MA,Li J,Zhang J,Huang Y,Wang W,Chen C,Liu G

更新日期：2016-01-01 00:00:00

abstract：:Neuroendocrine tumors (NETs) are tumors originated from neuroendocrine cells in the body. The localization and the detection of the extent of NETs are important for diagnosis and treatment, which should be individualized according to the tumor type, burden, and symptoms. Molecular imaging of NETs with high sensitivity...

journal_title：BioMed research international

authors： Wang L,Tang K,Zhang Q,Li H,Wen Z,Zhang H,Zhang H

更新日期：2013-01-01 00:00:00

abstract：:The explosive growth of high-throughput experimental methods and resulting data yields both opportunity and challenge for selecting the correct drug to treat both a specific patient and their individual disease. Ideally, it would be useful and efficient if computational approaches could be applied to help achieve opti...

journal_title：BioMed research international

authors： Cui H,Zhang M,Yang Q,Li X,Liebman M,Yu Y,Xie L

更新日期：2018-03-25 00:00:00

abstract：BACKGROUND:We aimed to identify certain genes related to response to infliximab (IFX) and biomarkers to predict the IFX effect for Japanese Crohn's disease (CD) patients by performing an association study of single nucleotide polymorphisms (SNPs) in candidate genes in the interleukin- (IL-) 17 signaling pathway with re...

journal_title：BioMed research international

authors： Urabe S,Isomoto H,Ishida T,Maeda K,Inamine T,Kondo S,Higuchi N,Sato K,Uehara R,Yajima H,Machida H,Chen CC,Fukuda Y,Takeshima F,Nakao K,Tsukamoto K

更新日期：2015-01-01 00:00:00

abstract：:The monoexponential model is widely used in quantitative biomedical imaging. Notable applications include apparent diffusion coefficient (ADC) imaging and pharmacokinetics. The application of ADC imaging to the detection of malignant tissue has in turn prompted several studies concerning optimal experiment design for ...

journal_title：BioMed research international

authors： Alipoor M,Maier SE,Gu IY,Mehnert A,Kahl F

更新日期：2015-01-01 00:00:00

abstract：:Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h af...

journal_title：BioMed research international

authors： Femia AP,Luceri C,Lodovici M,Crucitta S,Caderni G

更新日期：2016-01-01 00:00:00

abstract：CONTEXT:The 7th (2009) edition of the AJCC melanoma staging system incorporates tumor (Breslow) thickness, MR, and ulceration in stratifying T1 primary melanomas. Compared to the prior 6th (2001) edition, MR has replaced CL for thin melanomas. OBJECTIVE:We sought to identify and report differences of the classificatio...

journal_title：BioMed research international

authors： Chu VH,Tetzlaff MT,Torres-Cabala CA,Prieto VG,Bassett R Jr,Gershenwald JE,McLemore MS,Ivan D,Wang WL,Ross MI,Curry JL

更新日期：2013-01-01 00:00:00

abstract：:Colorectal cancer is the third most common form of cancer in developed countries and, despite the improvements achieved in its treatment options, remains as one of the main causes of cancer-related death. In this review, we first focus on colorectal carcinogenesis and on the genetic and epigenetic alterations involved...

journal_title：BioMed research international

authors： Lizarbe MA,Calle-Espinosa J,Fernández-Lizarbe E,Fernández-Lizarbe S,Robles MÁ,Olmo N,Turnay J

更新日期：2017-01-01 00:00:00

abstract：:The most expedient unit of the human body is its cell. Encapsulated within the cell are many infinitesimal entities and molecules which are protected by a cell membrane. The proteins that are associated with this lipid based bilayer cell membrane are known as membrane proteins and are considered to play a significant ...

journal_title：BioMed research international

authors： Butt AH,Khan SA,Jamil H,Rasool N,Khan YD

更新日期：2016-01-01 00:00:00

abstract：Objective:This study evaluated the bioactivity and physicochemical properties of three commercial calcium silicate-based endodontic materials (MTA, EndoSequence Root Repair Material putty, and Biodentine™). Material and Methods. Horizontal sections of 3 mm thickness from 18 root canals of human teeth were subjected to ...

journal_title：BioMed research international

authors： Talabani RM,Garib BT,Masaeli R

更新日期：2020-05-22 00:00:00

abstract：:Contrast enhanced magnetic resonance imaging (CE-MRI) has acquired a central role in the field of diagnosis and evaluation of breast cancer due to its high sensitivity; on the other hand, MRI has shown a variable specificity because of the wide overlap between the imaging features of benign and malignant lesions. Ther...

journal_title：BioMed research international

authors： Mazzei MA,Di Giacomo L,Fausto A,Gentili F,Mazzei FG,Volterrani L

更新日期：2018-10-21 00:00:00

abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

journal_title：BioMed research international

authors： Kaur K,Kaur G

更新日期：2013-01-01 00:00:00

abstract：:To overcome the issues connected to the use of autologous vascular grafts and artificial materials for reconstruction of small diameter (<6 mm) blood vessels, this study aimed to develop acellular matrix- (AM-) based vascular grafts. Rat iliac arteries were decellularized by a detergent-enzymatic treatment, whereas en...

journal_title：BioMed research international

authors： Dall'Olmo L,Zanusso I,Di Liddo R,Chioato T,Bertalot T,Guidi E,Conconi MT

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate if software simulation is practical for quantifying random error (RE) in phantom dosimetry. MATERIALS AND METHODS:We applied software error simulation to an existing dosimetry study. The specifications and the measurement values of this study were brought into the software (R version 3.0.2) to...

journal_title：BioMed research international

authors： Hoogeveen RC,Martens EP,van der Stelt PF,Berkhout WE

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to evaluate whether blood transfusions affect overall survival (OS) and progression-free survival (PFS) in newly diagnosed multiple myeloma (MM) patients without hematopoietic stem cell transplantation. A total of 181 patients were enrolled and divided into two groups: 68 patients in the tran...

journal_title：BioMed research international

authors： Fan L,Fu D,Zhang J,Huang H,Wang Q,Ye Y,Xie Q

更新日期：2017-01-01 00:00:00

abstract：Objective:The exact shape of the dose-response relationship between maternal body mass index (BMI) and the risk of congenital heart defects (CHDs) in infants has not been clearly defined yet. This study aims to further clarify the relationship between maternal obesity and the risk of CHDs in infants by an overall and d...

journal_title：BioMed research international

authors： Liu X,Ding G,Yang W,Feng X,Li Y,Liu H,Zhang Q,Ji L,Li D

更新日期：2019-07-07 00:00:00

abstract：:Melanoma is a human skin malignant tumor with high invasion and poor prognosis. The limited understanding of genomic alterations in melanomas in China impedes the diagnosis and therapeutic strategy selection. We conducted comprehensive genomic profiling of melanomas from 39 primary and metastatic formalin-fixed paraff...

journal_title：BioMed research international

authors： Luo Y,Zhang Z,Liu J,Li L,Xu X,Yao X,Dai Z,Wang X,Yang S,Wu H,Bu J,Wu Y,Xiang T,Li X

更新日期：2020-01-30 00:00:00

abstract：:A novel methylamine-selective amperometric bienzyme biosensor based on recombinant primary amine oxidase isolated from the recombinant yeast strain Saccharomyces cerevisiae and commercial horseradish peroxidase is described. Two amine oxidase preparations were used: free enzyme (AMO) and covalently immobilized on the ...

journal_title：BioMed research international

authors： Stasyuk NY,Smutok OV,Zakalskiy AE,Zakalska OM,Gonchar MV

更新日期：2014-01-01 00:00:00

abstract：Background:Spinal cord injury (SCI) is often associated with long-term impairments related to functional limitations in the sensorimotor system. The use of virtual reality (VR) technology may lead to increased motivation and engagement, besides allowing a wide range of possible tasks/exercises to be implemented in reha...

journal_title：BioMed research international

authors： de Araújo AVL,Neiva JFO,Monteiro CBM,Magalhães FH

更新日期：2019-11-13 00:00:00

abstract：:Autophagy is involved in the development of numerous illnesses, including ischemia/reperfusion (I/R). Endothelial nitric oxide synthase (eNOS) participates in the protective effects of ischemic postconditioning (IPostC). However, it remains unclear whether eNOS-mediated autophagy serves as a critical role in IPostC in...

journal_title：BioMed research international

authors： Shao J,Miao C,Geng Z,Gu M,Wu Y,Li Q

更新日期：2019-02-10 00:00:00

abstract：:Because of their high incidence and mortality solid cancers are a major health problem worldwide. Although several new biomarkers and potential targets for therapy have been identified through biomolecular research in the last years, the effects on patients' outcome are still unsatisfactory. Increasing evidence indica...

journal_title：BioMed research international

authors： Lastraioli E,Lottini T,Bencini L,Bernini M,Arcangeli A

更新日期：2015-01-01 00:00:00

abstract：:The similarity-based retrieval of lung nodule computed tomography (CT) images is an important task in the computer-aided diagnosis of lung lesions. It can provide similar clinical cases for physicians and help them make reliable clinical diagnostic decisions. However, when handling large-scale lung images with a gener...

journal_title：BioMed research international

authors： Pan L,Qiang Y,Yuan J,Wu L

更新日期：2016-01-01 00:00:00

abstract：:This study tested the hypothesis that sensitivity of Escherichia coli to lactic acid at concentrations relevant for fermented sausages (pH 4.6, 150 mM lactic acid, aw = 0.92, temperature = 20 or 27°C) increases with increasing growth rate. For E. coli strain 683 cultured in TSB in chemostat or batch, subsequent inacti...

journal_title：BioMed research international

authors： Lindqvist R,Barmark G

更新日期：2014-01-01 00:00:00

abstract：:Correlation of parametrized image texture features (ITF) analyses conducted in different regions of interest (ROIs) overcomes limitations and reliably reflects image quality. The aim of this study is to propose a nonparametrical method and classify the quality of a magnetic resonance (MR) image that has undergone cont...

journal_title：BioMed research international

authors： Obuchowicz R,Piórkowski A,Urbanik A,Strzelecki M

更新日期：2019-11-20 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/7865747.]. ...

journal_title：BioMed research international

authors： Zhang N,Tian H,Huang D,Meng X,Guo W,Wang C,Yin X,Zhang H,Jiang B,He Z,Wang Z

更新日期：2018-05-14 00:00:00

abstract：OBJECTIVE:Radiopharmaceutical production process must adhere to current good manufacturing process (CGMP) compliance to ensure the quality of precursor, prodrug (active pharmaceutical ingredient, API), and the final drug product that meet acceptance criteria. We aimed to develop an automated system for production of CG...

journal_title：BioMed research international

authors： Chi YT,Chu PC,Chao HY,Shieh WC,Chen CC

更新日期：2014-01-01 00:00:00

abstract：Background:Pyroptosis, a novel form of inflammatory programmed cell death, was recently found to be a cause of mucosal barrier defect. In our pervious study, CD147 expression was documented to increase in intestinal tissue of inflammatory bowel disease (IBD). Objective:The aim of this study was to determine the functi...

journal_title：BioMed research international

authors： Xu Z,Liu R,Huang L,Xu Y,Su M,Chen J,Geng L,Xu W,Gong S

更新日期：2020-06-30 00:00:00