The establishment of metabolic syndrome model by induction of fructose drinking water in male Wistar rats.

abstract：:The objective of this study was to investigate the iontophoretic delivery of lidocaine hydrochloride through porcine skin and to compare the effects of modulated alternating and direct current iontophoresis. Continuous and modulated iontophoresis was applied for one hour and two hours (0-1 h and 4-5th h) using a 1% w/...

journal_title：BioMed research international

authors： Bhatia G,Banga AK

更新日期：2014-01-01 00:00:00

abstract：:The present study evaluated the anti-inflammatory and analgesic effects of the superoxide dismutase mimetic agent tempol in superoxide anion-induced pain and inflammation. Mice were treated intraperitoneally with tempol (10-100 mg/kg) 40 min before the intraplantar injection of a superoxide anion donor, potassium supe...

journal_title：BioMed research international

authors： Bernardy CCF,Zarpelon AC,Pinho-Ribeiro FA,Calixto-Campos C,Carvalho TT,Fattori V,Borghi SM,Casagrande R,Verri WA Jr

更新日期：2017-01-01 00:00:00

abstract：:Mixed-phase TiO2 nanocomposite thin films consisting of anatase and rutile prepared on commercially pure Ti sheets via the electrochemical anodization and annealing treatments were investigated in terms of their photocatalytic activity for antibacterial use around dental implants. The resulting films were characterize...

journal_title：BioMed research international

authors： Yeniyol S,Mutlu I,He Z,Yüksel B,Boylan RJ,Ürgen M,Karabuda ZC,Basegmez C,Ricci JL

更新日期：2015-01-01 00:00:00

abstract：CONTEXT:IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. PATIENTS AND METHODS:We studied 64 ad...

journal_title：BioMed research international

authors： Ribeiro TC,Jorge AA,Almeida MQ,Mariani BM,Nishi MY,Mendonca BB,Fragoso MC,Latronico AC

更新日期：2014-01-01 00:00:00

abstract：:Due to anthropogenic activities the relative concentrations of cadmium and manganese have increased in the marine environment. Cephalopods are able to accumulate such metals and, as inhabitant of coastal waters, Octopus vulgaris is continuously exposed to anthropogenic activities. Since no study is available on the ef...

journal_title：BioMed research international

authors： Nicosia A,Salamone M,Mazzola S,Cuttitta A

更新日期：2015-01-01 00:00:00

abstract：:Stem cell-based therapy has been considered as a promising option in the treatment of ischemic heart disease. Although stem cell administration resulted in the temporary improvement of myocardial contractility in the majority of studies, the formation of new cardiomyocytes within the injured myocardium has not been co...

journal_title：BioMed research international

authors： Belostotskaya G,Hendrikx M,Galagudza M,Suchkov S

更新日期：2020-03-03 00:00:00

abstract：:Diethylnitrosamine (DEN) induces hepatocarcinogenesis, increasing mitotic hepatocytes and leading to chronic inflammation. In addition, type 1 diabetes mellitus (T1DM) is also characterized by a proinflammatory state and by requiring insulin exogenous treatment. Given the association of diabetes, insulin treatment, an...

journal_title：BioMed research international

authors： Arboatti AS,Lambertucci F,Sedlmeier MG,Pisani G,Monti J,Álvarez ML,Francés DEA,Ronco MT,Carnovale CE

更新日期：2018-04-23 00:00:00

abstract：:Cardiac computed tomography angiography (CCTA) is widely used as a diagnostic tool for evaluation of coronary artery disease (CAD). Despite the excellent capability to rule-out CAD, CCTA may overestimate the degree of stenosis; furthermore, CCTA analysis can be time consuming, often requiring advanced postprocessing t...

journal_title：BioMed research international

authors： Muscogiuri G,Van Assen M,Tesche C,De Cecco CN,Chiesa M,Scafuri S,Guglielmo M,Baggiano A,Fusini L,Guaricci AI,Rabbat MG,Pontone G

更新日期：2020-12-16 00:00:00

abstract：:Integrins are a family of membrane-spanning proteins that are important receptors for cell adhesion to extracellular matrix proteins. They also provide connections between the extracellular environment and intracellular cytoskeletons and are responsible for activation of many intracellular signaling pathways. In vitro...

journal_title：BioMed research international

authors： Zhong Y,Wang J,Luo X

更新日期：2013-01-01 00:00:00

abstract：:A familiarity with the anatomy of some types of bone anomalies is necessary for clinicians involved in many medical areas. The aim of this paper is to review the newest literature concerning the morphology, embryology, clinical image, and therapeutic methods of the cervical ribs in the humans. The incidence of cervica...

journal_title：BioMed research international

authors： Spadliński Ł,Cecot T,Majos A,Stefańczyk L,Pietruszewska W,Wysiadecki G,Topol M,Polguj M

更新日期：2016-01-01 00:00:00

abstract：:Proteinuria is an independent risk factor for end-stage renal disease (ESRD) (Shankland, 2006). Recent studies highlighted the mechanisms of podocyte injury and implications for potential treatment strategies in proteinuric kidney diseases (Zhang et al., 2012). Reactive oxygen species (ROS) are cellular signals which ...

journal_title：BioMed research international

authors： Chen S,Meng XF,Zhang C

更新日期：2013-01-01 00:00:00

abstract：UNLABELLED:Isoniazid (INH), a key agent in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. Patients treated with INH can be classified as fast, intermediate, and slow acetylators. The objective of this study was to explore the relationship...

journal_title：BioMed research international

authors： Zabost A,Brzezińska S,Kozińska M,Błachnio M,Jagodziński J,Zwolska Z,Augustynowicz-Kopeć E

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Apoptosis and matrix metalloproteinase (MMP-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. The aim of this study was to determine the effect of supracervical apposition and spontaneous...

journal_title：BioMed research international

authors： Chai M,Walker SP,Riley C,Rice GE,Permezel M,Lappas M

更新日期：2013-01-01 00:00:00

abstract：:The role of α-fetoprotein (AFP) in the surveillance and diagnosis of hepatocellular carcinoma (HCC) has been questioned in recent years due to its low sensitivity and specificity. In addition to AFP, several new serum biomarkers, such as lens culinaris agglutinin-reactive fraction of AFP (AFP-L3) and des-gamma-carboxy...

journal_title：BioMed research international

authors： Wang X,Zhang Y,Yang N,He H,Tao X,Kou C,Jiang J

更新日期：2020-09-17 00:00:00

abstract：Introduction:Limitations in breeding source reduction practices, development of insecticide resistance in mosquitoes, and ill effects of chemical controlling methods on human and ecosystem health have motivated Sri Lankan authorities working for dengue control to seek for alternative, ecofriendly, and sustainable appro...

journal_title：BioMed research international

authors： Samanmali C,Udayanga L,Ranathunge T,Perera SJ,Hapugoda M,Weliwitiya C

更新日期：2018-12-03 00:00:00

abstract：Background:Fingertips are a common site for hand injuries. The ideal substitute for fingertip pulp is tissue that matches texturally with minimal donor site morbidity. We described anatomical findings from cadaveric studies and the reliability of the palmar ulnar artery perforator (PUAP) free flap techniques for the re...

journal_title：BioMed research international

authors： Pak CS,Jeon JI,Myung Y,Lee YK,Kim BJ,Jeong JH,Kim BK

更新日期：2018-05-09 00:00:00

abstract：:Cervical cancer is one of the malignant tumors that seriously threaten women's health. The mechanism of development needs to be deeply studied. In recent years, lncRNA has been identified as one of the important factors affecting the malignant progression of tumors. In this study, we illustrated the important mechanis...

journal_title：BioMed research international

authors： Hu T,Zhang Q,Gao L

更新日期：2020-01-03 00:00:00

abstract：INTRODUCTION:Osteomyelitis is a severe orthopaedic complication which is difficult to diagnose and treat. Previous experimental studies mainly focussed on evaluating osteomyelitis in the presence of an implant or used a sclerosing agent to promote infection onset. In contrast, we focused on the longitudinal assessment ...

journal_title：BioMed research international

authors： Odekerken JC,Walenkamp GH,Brans BT,Welting TJ,Arts JJ

更新日期：2014-01-01 00:00:00

abstract：:This paper presents different applications, in various foodstuffs, by a novel electronic nose (EN) based on a mixed metal oxide sensors array composed of thin films as well as nanowires. The electronic nose used for this work has been done, starting from the commercial model EOS835 produced by SACMI Scarl. The SENSOR ...

journal_title：BioMed research international

authors： Sberveglieri V,Carmona EN,Comini E,Ponzoni A,Zappa D,Pirrotta O,Pulvirenti A

更新日期：2014-01-01 00:00:00

abstract：:Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibact...

journal_title：BioMed research international

authors： Bogacz M,Morawiec T,Śmieszek-Wilczewska J,Janowska-Bogacz K,Bubiłek-Bogacz A,Rój R,Pinocy K,Mertas A

更新日期：2019-10-07 00:00:00

abstract：:Poly(ADP-ribose) polymerase (PARP) inhibitors have proven to be successful agents in inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached clinical trial testing for treatment in different cancers, and, recently, Olaparib (AZD2281) has gained both United States Food and Drug Admini...

journal_title：BioMed research international

authors： Murata S,Zhang C,Finch N,Zhang K,Campo L,Breuer EK

更新日期：2016-01-01 00:00:00

abstract：Background and Aims:Concordance between transient elastography (TE) and ultrasonography (US) in assessing liver fibrosis in patients with chronic hepatitis B (CHB) and concurrent nonalcoholic fatty liver disease (NAFLD) has been rarely studied. This study aimed to evaluate the individual and combined performances of TE...

journal_title：BioMed research international

authors： Zhang GL,Zhao QY,Lin CS,Hu ZX,Zhang T,Gao ZL

更新日期：2019-01-23 00:00:00

abstract：:A series of halo-substituted mixed ester/amide-based analogues 4a-l have been prepared as jack bean urease inhibitor, which showed good to excellent inhibition of enzyme activity. The role of halo-substituted benzoyl moieties and alkyl substituted anilines in urease inhibitory kinetics was also investigated. The alkyl...

journal_title：BioMed research international

authors： Rashid M,Rafique H,Roshan S,Shamas S,Iqbal Z,Ashraf Z,Abbas Q,Hassan M,Qureshi ZUR,Asad MHHB

更新日期：2020-12-24 00:00:00

abstract：BACKGROUND:Sarcopenia is the presence of low muscle mass and low muscle function. The aim of this study was to establish cutoffs for low muscle mass using three published methods and to compare the prevalence of sarcopenia in older Australians. METHODS:Gender specific cutoffs levels were identified for low muscle mass...

journal_title：BioMed research international

authors： Yu S,Appleton S,Adams R,Chapman I,Wittert G,Visvanathan T,Visvanathan R

更新日期：2014-01-01 00:00:00

abstract：:A metabolic disorder is considered one of the hallmarks of cancer. Multiple differentially expressed metabolic genes have been identified in colon cancer (CC), and their biological functions and prognostic values have been well explored. The purpose of the present study was to establish a metabolic signature to optimi...

journal_title：BioMed research international

authors： Luo D,Shan Z,Liu Q,Cai S,Li Q,Li X

更新日期：2020-11-17 00:00:00

abstract：:This 12-week clinical study evaluated the impact of 10% CPP-ACP and 5% sodium fluoride varnish regimes on the regression of nonorthodontic white spot lesions (WSLs). The study included 21 children with 101 WSLs who were randomised into four treatment regimes: weekly clinical applications of fluoride varnish for the fi...

journal_title：BioMed research international

authors： Güçlü ZA,Alaçam A,Coleman NJ

更新日期：2016-01-01 00:00:00

abstract：Background:The pathogenesis of abdominal aortic aneurysm (AAA) is characterized by atherosclerosis with chronic inflammation in the aortic wall. Montelukast is a selective cys-LT 1 receptor antagonist that can suppress atherosclerotic diseases. We evaluated the in vitro properties of montelukast and its in vivo activit...

journal_title：BioMed research international

authors： Kawai Y,Narita Y,Yamawaki-Ogata A,Usui A,Komori K

更新日期：2019-05-27 00:00:00

abstract：:The aim of this study was to develop a freeze-drying protocol facilitating successful processing of plant material containing the small surface antigen of hepatitis B virus (S-HBsAg) while preserving its VLP structure and immunogenicity. Freeze-drying of the antigen in lettuce leaf tissue, without any isolation or pur...

journal_title：BioMed research international

authors： Czyż M,Dembczyński R,Marecik R,Wojas-Turek J,Milczarek M,Pajtasz-Piasecka E,Wietrzyk J,Pniewski T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:To investigate the anesthetic management in premature infants with retinopathy of prematurity (ROP) treated with intravitreal bevacizumab (IVB) injections. METHODS:A retrospective chart review was performed for the patients with ROP who had IVB injection. Clinical characteristics, demographic variables, ane...

journal_title：BioMed research international

authors： Tokgöz O,Sahin A,Tüfek A,Cınar Y,Güzel A,Ciftçi T,Celik F,Yüksel H

更新日期：2013-01-01 00:00:00

abstract：:Esthetic evaluation of cleft lip and palate rehabilitation outcomes may assist in the determination of new surgical interventions and aid in reevaluation of treatment protocols. Our objective was to compare esthetics assessments of the nasolabial region in children with a unilateral cleft lip and palate between health...

journal_title：BioMed research international

authors： Paiva TS,Andre M,Paiva WS,Mattos BS

更新日期：2014-01-01 00:00:00