Amplification of the insulin-like growth factor 1 receptor gene is a rare event in adrenocortical adenocarcinomas: searching for potential mechanisms of overexpression.

abstract：:Our aim was to verify the effects of prednisone related to gastrointestinal motility, intestinal histology, and mucosal mast cells in rats. Two-month-old male Wistar rats were randomly assigned to control group (vehicle) animals receiving saline 0.9% (n = 7) or treated orally with 0.625 mg/kg/day of prednisone (n = 7)...

journal_title：BioMed research international

authors： de Lima MB,Gama LA,Hauschildt AT,Dall'Agnol DJR,Corá LA,Americo MF

更新日期：2017-01-01 00:00:00

abstract：Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...

journal_title：BioMed research international

authors： Kartinah NT,Fadilah F,Ibrahim EI,Suryati Y

更新日期：2019-11-11 00:00:00

abstract：:DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu elements is an impor...

journal_title：BioMed research international

authors： Luo Y,Lu X,Xie H

更新日期：2014-01-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial ...

journal_title：BioMed research international

authors： Osayi SN,Bloomston M,Schmidt CM,Ellison EC,Muscarella P

更新日期：2014-01-01 00:00:00

abstract：:Objective. To evaluate the efficacy of bundle intervention on healthcare-associated (HA) methicillin-resistant Staphylococcus Aureus (MRSA) infection in the neonatal intensive care unit (NICU). Methods. In this study, 11,277 infants having undergone treatment at the NICU in Xiamen, China, from January 2014 to February...

journal_title：BioMed research international

authors： Huang H,Ran J,Yang J,Li P,Zhuang G

更新日期：2019-07-10 00:00:00

abstract：:Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA). However, there have been unsatisfactory success rates for end-stage ONFH. The auth...

journal_title：BioMed research international

authors： Zhao D,Liu B,Wang B,Yang L,Xie H,Huang S,Zhang Y,Wei X

更新日期：2015-01-01 00:00:00

abstract：:Background and Aims. CIN is a major and serious complication following PCI in patients with ACS. It is unclear whether a higher serum ferritin level is associated with an increased risk of CIN in high-risk patients. Thus, we conducted this study to assess the predictive value of SF for the risk of CIN after PCI. Metho...

journal_title：BioMed research international

authors： Zhu B,Hou J,Gong Y,Yan G,Wang Q,Wang D,Qiao Y,Chen Y,Tang C

更新日期：2016-01-01 00:00:00

abstract：:Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]IPQA derivative as ...

journal_title：BioMed research international

authors： Yeh SH,Lin CF,Kong FL,Wang HE,Hsieh YJ,Gelovani JG,Liu RS

更新日期：2013-01-01 00:00:00

abstract：:Liver transplantation is the best treatment option for early-stage hepatocellular carcinoma, liver cirrhosis, fulminant liver failure, and end-stage liver diseases. Even though advances in surgical techniques and perioperative care have improved postoperative outcomes, perioperative cardiovascular complications are a ...

journal_title：BioMed research international

authors： Choi JM,Kong YG,Kang JW,Kim YK

更新日期：2017-01-01 00:00:00

abstract：:A study of myelostimulating activity of ionic compounds-trimecaine alkyl iodide derivatives under the cipher BIV (BIV-117, BIV-118, and BIV-119) was conducted on a model of doxorubicin pancytopenia in white laboratory rats. It was established that the compounds BIV-117 and BIV-119 had a pronounced leukopoiesis-stimula...

journal_title：BioMed research international

authors： Baktybayeva L,Yu V,Zazybin A,Zolotareva D,Dauletbakov A

更新日期：2020-01-13 00:00:00

abstract：:A kind of chemically cross-linked pH-sensitive hydrogels based on methoxyl poly(ethylene glycol)-poly(caprolactone)-acryloyl chloride (MPEG-PCL-AC, PECA), poly(ethylene glycol) methyl ether methacrylate (MPEGMA, MEG), N,N-methylenebisacrylamide (BIS), and itaconic acid (IA) were prepared without using any organic solv...

journal_title：BioMed research international

authors： Tan L,Xu X,Song J,Luo F,Qian Z

更新日期：2013-01-01 00:00:00

abstract：:Human epididymis protein 4 (HE4) is an available tumor biomarker mainly for detecting ovarian cancer. However, it is unknown whether it can be a novel indicator for diagnosis of diabetic kidney disease (DKD). The aim of this study was to investigate the possibility of serum HE4 as a novel biomarker for DKD in patients...

journal_title：BioMed research international

authors： Zhang M,Zhao B,Xie J,Liang Y,Yang Z

更新日期：2019-11-11 00:00:00

abstract：:Renal dysfunction is one of the most common complications of liver cirrhosis and is associated with increased morbidity and mortality. However, no available technology can simultaneously support liver and renal function in these patients. The aim of this study was to evaluate the safety and efficacy of an artificial l...

journal_title：BioMed research international

authors： Feng L,He G,Cai L,Fu C,Li Y,Weng J,Huo X,Peng Q,Gao Y

更新日期：2018-05-24 00:00:00

abstract：:Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, ge...

journal_title：BioMed research international

authors： Abdullah Al-Dhabi N,Srigopalram S,Ilavenil S,Kim YO,Agastian P,Baaru R,Balamurugan K,Choi KC,Valan Arasu M

更新日期：2016-01-01 00:00:00

abstract：:Nematodes infections are responsible for debilitating conditions and economic losses in domestic animals as well as livestock and are considered an important public health problem due to the high prevalence in humans. The nematode resistance for drugs has been reported for livestock, highlighting the importance for de...

journal_title：BioMed research international

authors： Ferreira SR,Mendes TA,Bueno LL,de Araújo JV,Bartholomeu DC,Fujiwara RT

更新日期：2015-01-01 00:00:00

abstract：Background:The kaya business is known to pose significant health-related risks to female migrants. This study sought to explore the health-related concerns of female head porters in the Mallam Atta market, Accra, Ghana. Methods:A qualitative study was conducted in which twenty female head porters at the Mallam Atta ma...

journal_title：BioMed research international

authors： Nyarko SH,Tahiru AM

更新日期：2018-02-13 00:00:00

abstract：:Liver cell culture within three-dimensional structures provides an improved culture system for various applications in basic research, pharmacological screening, and implantable or extracorporeal liver support. Biodegradable calcium-based scaffolds in such systems could enhance liver cell functionality by providing en...

journal_title：BioMed research international

authors： Finoli A,Schmelzer E,Over P,Nettleship I,Gerlach JC

更新日期：2016-01-01 00:00:00

abstract：:Netrins, a family of laminin-related proteins, were originally identified as axonal guidance molecules. Subsequently, netrins were found to modulate various biological processes including morphogenesis, tumorogenesis, adhesion, and, recently, angiogenesis. In human placenta, the most vascularized organ, the presence o...

journal_title：BioMed research international

authors： Dakouane-Giudicelli M,Alfaidy N,de Mazancourt P

更新日期：2014-01-01 00:00:00

abstract：:Several studies suggested that migraine attack onset shows a circadian variation; however, there has not been an overview and synthesis of these findings. A PubMed search with keywords "migraine" AND "circadian" resulted in ten studies directly investigating this topic. Results of these studies mostly show that migrai...

journal_title：BioMed research international

authors： Baksa D,Gecse K,Kumar S,Toth Z,Gal Z,Gonda X,Juhasz G

更新日期：2019-08-25 00:00:00

abstract：Background:The purpose of this study was to examine the physical activity patterns and health-related fitness levels of adolescents within the Juvenile Justice System. Methods:Participants included 68 adolescents (Mean age = 17.1 ± 1.0 years) in two secure Juvenile Justice correctional facilities in the Western USA. M...

journal_title：BioMed research international

authors： Brusseau TA,Burns RD,Hannon JC

更新日期：2018-07-15 00:00:00

abstract：:Background. The epidemiology of atopic dermatitis (AD) in Chinese outpatients is yet to be clarified. Objectives. To investigate population-based prevalence and clinical features of AD in Chinese outpatients. Methods. A multicenter cross-sectional study was conducted in outpatients with eczema or dermatitis from 39 te...

journal_title：BioMed research international

authors： Wang X,Li LF,Zhao DY,Shen YW

更新日期：2016-01-01 00:00:00

abstract：:Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic data, biological pathw...

journal_title：BioMed research international

authors： Chen X,Wang Y,Wang P,Lian B,Li C,Wang J,Li X,Jiang W

更新日期：2015-01-01 00:00:00

abstract：AIMS/INTRODUCTION:Determining the prevalence of diabetes and its cardiovascular complications and all-cause mortality in older chronic complex patients. MATERIALS AND METHODS:We carried out a multicenter retrospective study and included a randomized sample of 932 CCP people. We assessed the prevalence of diabetes acco...

journal_title：BioMed research international

authors： Clua-Espuny JL,González-Henares MA,Queralt-Tomas MLL,Campo-Tamayo W,Muria-Subirats E,Panisello-Tafalla A,Lucas-Noll J

更新日期：2017-01-01 00:00:00

abstract：:This study aimed to examine the expression of and the relationship between CD44V6, CDH11, and β-catenin. The expression of these cell adhesion molecules was detected in 90 osteosarcoma and 20 osteochondroma specimens using immunohistochemistry. Associations between these parameters and clinicopathological data were al...

journal_title：BioMed research international

authors： Deng Z,Niu G,Cai L,Wei R,Zhao X

更新日期：2013-01-01 00:00:00

abstract：:The objective of this study was to perform a structural characterization and evaluate the in vitro safety profile and in vitro antioxidant activity of liquid crystalline systems (LCS) with and without retinyl palmitate (RP). LCS containing polyether functional siloxane (PFS) as a surfactant, silicon glycol copolymer (...

journal_title：BioMed research international

authors： Oliveira MB,do Prado AH,Bernegossi J,Sato CS,Lourenço Brunetti I,Scarpa MV,Leonardi GR,Friberg SE,Chorilli M

更新日期：2014-01-01 00:00:00

abstract：Results:The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (Dmax) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for Dmean of the heart and left ventricle ...

journal_title：BioMed research international

authors： Hu J,Han G,Lei Y,Xu X,Ge W,Ruan C,Chang S,Zhang A,Li X

更新日期：2020-03-26 00:00:00

abstract：:Each year, hundreds of millions of people travel across international borders or even oceans, and up to 230 million may remain for long periods. Among these, 3-5 million settle permanently in their new homes, with about 1 million migrating permanently to the United States of America. This may result in transport of pa...

journal_title：BioMed research international

authors： Smith Darr J,Conn DB

更新日期：2015-01-01 00:00:00

abstract：:Tyrosine kinase inhibitors (TKI) belong to a new class of molecular multitargeted anticancer therapy which targets different growth factor receptors and hence attenuates cancer cell survival and growth. Since their introduction as adjunct treatment for renal cell carcinoma and gastrointestinal stromal tumors (GIST), a...

journal_title：BioMed research international

authors： Ahmadieh H,Salti I

更新日期：2013-01-01 00:00:00

abstract：Objective:To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods:CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and...

journal_title：BioMed research international

authors： Wang H,Nie P,Dong C,Li J,Huang Y,Hao D,Xu W

更新日期：2018-03-06 00:00:00

abstract：:This study was performed to assess the efficacy and safety of a topical diclofenac solution in patients with knee osteoarthritis (OA). PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were searched for randomized controlled trials until June 2020. The WOMAC pain, stiffness, physical function subs...

journal_title：BioMed research international

authors： Ling T,Li JJ,Xu RJ,Wang B,Ge WH

更新日期：2020-11-24 00:00:00