Activation of Leukopoiesis in Rat Blood with Trimecaine-Based Ionic Compounds.

Abstract:

:A study of myelostimulating activity of ionic compounds-trimecaine alkyl iodide derivatives under the cipher BIV (BIV-117, BIV-118, and BIV-119) was conducted on a model of doxorubicin pancytopenia in white laboratory rats. It was established that the compounds BIV-117 and BIV-119 had a pronounced leukopoiesis-stimulating activity, exceeding the activity of the methyluracil as a comparison drug. Compounds BIV-117 and BIV-119 had erythropoiesis- and thrombocytopoiesis-stimulating activity at the level of methyluracil.

journal_name

Biomed Res Int

authors

Baktybayeva L,Yu V,Zazybin A,Zolotareva D,Dauletbakov A

doi

10.1155/2020/7636290

subject

Has Abstract

pub_date

2020-01-13 00:00:00

pages

7636290

eissn

2314-6133

issn

2314-6141

journal_volume

2020

pub_type

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