Abstract:
:Trichoderma spp. are important biocontrol filamentous fungi, which are widely used for their adaptability, broad antimicrobial spectrum, and various antagonistic mechanisms. In our previous studies, we cloned thga1 gene encoding GαI protein from Trichoderma harzianum Th-33. Its knockout mutant showed that the growth rate, conidial yield, cAMP level, antagonistic action, and hydrophobicity decreased. Therefore, Illumina RNA-seq technology (RNA-seq) was used to determine transcriptomic differences between the wild-type strain and thga1 mutant. A total of 888 genes were identified as differentially expressed genes (DEGs), including 427 upregulated and 461 downregulated genes. All DEGs were assigned to KEGG pathway databases, and 318 genes were annotated in 184 individual pathways. KEGG analysis revealed that these unigenes were significantly enriched in metabolism and degradation pathways. GO analysis suggested that the majority of DEGs were associated with catalytic activities and metabolism processes that encode carbohydrate-active enzymes, secondary metabolites, secreted proteins, or transcription factors. According to the functional annotation of these DEGs by KOG, the most abundant group was "secondary metabolite biosynthesis, transport, and catabolism." Further studies for functional characterization of candidate genes and pathways reported in this paper are necessary to further define the G protein signaling system in T. harzianum.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Sun Q,Jiang X,Pang L,Wang L,Li Mdoi
10.1155/2016/8329513subject
Has Abstractpub_date
2016-01-01 00:00:00pages
8329513eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章abstract::Vitamin D deficiency is common in pregnant women and infants. The present study aimed to investigate the effects of vitamin D restricted diet on the Wistar rats offspring penis morphology. Mother rats received either standard diet (SC) or vitamin D restricted (VitD) diet. At birth, offspring were divided into SC/SC (f...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6030646
更新日期:2018-04-23 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2020-10-03 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/909860
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1817906
更新日期:2019-08-05 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/981471
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/3691913
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/607137
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/182846
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
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更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 已发布勘误
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更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/5420345
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/413076
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/386265
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/1854027
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2670658
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/723035
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/867140
更新日期:2015-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2019/4370258.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2020/2049759
更新日期:2020-07-16 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/3762179
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/157295
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/742180
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/491649
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/7857345
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/858907
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6182464
更新日期:2020-06-07 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/5953036
更新日期:2019-12-04 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
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更新日期:2018-12-10 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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更新日期:2014-01-01 00:00:00