A comprehensive review of contemporary role of local treatment of the primary tumor and/or the metastases in metastatic prostate cancer.

Abstract:

:To provide an overview of the currently available literature regarding local control of primary tumor and oligometastases in metastatic prostate cancer and salvage lymph node dissection of clinical lymph node relapse after curative treatment of prostate cancer. Evidence Acquisition. A systematic literature search was conducted in 2014 to identify abstracts, original articles, review articles, research articles, and editorials relevant to the local control in metastatic prostate cancer. Evidence Synthesis. Local control of primary tumor in metastatic prostate cancer remains experimental with low level of evidence. The concept is supported by a growing body of genetic and molecular research as well as analogy with other cancers. There is only one retrospective observational population based study showing prolonged survival. To eradicate oligometastases, several options exist with excellent local control rates. Stereotactic body radiotherapy is safe, well tolerated, and efficacious treatment for lymph node and bone lesions. Both biochemical and clinical progression are slowed down with a median time to initiate ADT of 2 years. Salvage lymph node dissection is feasible in patients with clinical lymph node relapse after local curable treatment. Conclusion. Despite encouraging oncologic midterm results, a complete cure remains elusive in metastatic prostate cancer patients. Further advances in imaging are crucial in order to rapidly evolve beyond the proof of concept.

journal_name

Biomed Res Int

authors

Aoun F,Peltier A,van Velthoven R

doi

10.1155/2014/501213

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

501213

eissn

2314-6133

issn

2314-6141

journal_volume

2014

pub_type

杂志文章,评审
  • Neural Network Prediction of Corn Stover Saccharification Based on Its Structural Features.

    abstract::The classic assay for a large population biomass is time-consuming, labor intensive, and chemically expensive. This paper would find out a rapid assay for predicting biomass digestibility from biomass structural features without hydrolysis. We examined the 62 representative corn stover accessions that displayed a dive...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/9167508

    authors: Gao L,Chen S,Zhang D

    更新日期:2018-08-12 00:00:00

  • Sliding and lower limb mechanics during sit-stand-sit transitions with a standing wheelchair.

    abstract:PURPOSE:This study aimed to investigate the shear displacement between the body and backrest/seat, range of motion (ROM), and force acting on the lower limb joints during sit-stand-sit transitions by operating an electric-powered standing wheelchair. METHODS AND MATERIALS:The amounts of sliding along the backrest and ...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/236486

    authors: Yang YS,Chen MD,Fang WC,Chang JJ,Kuo CC

    更新日期:2014-01-01 00:00:00

  • Call to Action for Nurses/Nursing.

    abstract::The 13 million nurses worldwide constitute most of the global healthcare workforce and are uniquely positioned to engage with others to address disparities in healthcare to achieve the goal of better health for all. A new vision for nurses involves active participation and collaboration with international colleagues a...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2016/3127543

    authors: Premji SS,Hatfield J

    更新日期:2016-01-01 00:00:00

  • Tumor Take Rate Optimization for Colorectal Carcinoma Patient-Derived Xenograft Models.

    abstract::Background. For development of individualized treatment on a routine basis, transfer of patients' tumor tissue in a xenograft model (i.e., generation of patient-derived xenografts (PDX)) is desirable for molecular, biochemical, or functional analyses. Drawbacks are dissatisfactory tumor take rates, the necessity of fa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/1715053

    authors: Gock M,Kühn F,Mullins CS,Krohn M,Prall F,Klar E,Linnebacher M

    更新日期:2016-01-01 00:00:00

  • Biological Activities of Tetrodotoxin-Producing Enterococcus faecium AD1 Isolated from Puffer Fishes.

    abstract::Puffer fishes were collected from the central sea in Vietnam from spring to summer season. The eggs were incubated in MRS broth that was used to test the toxicity in mice and isolate the lactic acid bacteria community that could produce tetrodotoxin (TTX). Thin layer chromatography (TLC) and high performance lipid chr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/973235

    authors: Nguyen TH,Nguyen HN,Nghe DV,Nguyen KH

    更新日期:2015-01-01 00:00:00

  • Extensive Use of 3D Nonfluoroscopic Mapping Systems for Reducing Radiation Exposure during Catheter Ablation Procedures: An Analysis of 10 Years of Activity.

    abstract:Purpose:3D nonfluoroscopic mapping systems (NMSs) are generally used in the catheter ablation (CA) of complex ventricular and atrial arrhythmias. The aim of this study was to evaluate the efficacy, safety, and long-term effect of the extended, routine use of NMSs for CA. Methods:Our study involved 1028 patients who un...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/4217076

    authors: Marini M,Martin M,Ravanelli D,Del Greco M,Quintarelli S,Guarracini F,Coser A,Valentini A,Bonmassari R

    更新日期:2019-03-10 00:00:00

  • The Emerging Role of lncRNAs in Spinal Cord Injury.

    abstract::Spinal cord injury (SCI) is a highly debilitating disease and is increasingly being recognized as an important global health priority. However, the mechanisms underlying SCI have not yet been fully elucidated, and effective therapies for SCI are lacking. Long noncoding RNAs (lncRNAs), which form a major class of nonco...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/3467121

    authors: Wang F,Liu J,Wang X,Chen J,Kong Q,Ye B,Li Z

    更新日期:2019-10-15 00:00:00

  • First Description of Macrolide-Resistant Mycoplasma pneumoniae in Adults with Community-Acquired Pneumonia in Italy.

    abstract:Background:Mycoplasma pneumoniae is a common cause of community-acquired pneumonia (CAP). This cross-sectional study aimed to determine the prevalence of macrolide-resistant M. pneumoniae strains in a convenience series of 234 adult hospitalised and nonhospitalised subjects with a diagnosis of CAP in January 2013 to Ap...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/7168949

    authors: Loconsole D,De Robertis AL,Mallamaci R,Sallustio A,Morea A,Prato R,Quarto M,Martinelli D,Chironna M

    更新日期:2019-03-17 00:00:00

  • The Epidemiological, Morphological, and Clinical Aspects of the Cervical Ribs in Humans.

    abstract::A familiarity with the anatomy of some types of bone anomalies is necessary for clinicians involved in many medical areas. The aim of this paper is to review the newest literature concerning the morphology, embryology, clinical image, and therapeutic methods of the cervical ribs in the humans. The incidence of cervica...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1155/2016/8034613

    authors: Spadliński Ł,Cecot T,Majos A,Stefańczyk L,Pietruszewska W,Wysiadecki G,Topol M,Polguj M

    更新日期:2016-01-01 00:00:00

  • Comparative Analysis and Classification of Cassette Exons and Constitutive Exons.

    abstract::Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/7323508

    authors: Cui Y,Cai M,Stanley HE

    更新日期:2017-01-01 00:00:00

  • Efficiency of barley bran and oat bran in ameliorating blood lipid profile and the adverse histological changes in hypercholesterolemic male rats.

    abstract::The efficiency of oat bran and barley bran in lowering the induced hyperlipidemia and hypercholesterolemia in blood of male Albino rats (Rattus rattus) was studied. Twenty rats were divided into four groups each consisted of five rats and fed the specified test diets for eight weeks. The first group (G1) is the negati...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/263594

    authors: El Rabey HA,Al-Seeni MN,Amer HM

    更新日期:2013-01-01 00:00:00

  • Pediococcus acidilactici P25 Protected Caenorhabditis elegans against Enterotoxigenic Escherichia coli K88 Infection and Transcriptomic Analysis of Its Potential Mechanisms.

    abstract::Enterotoxigenic Escherichia coli (ETEC) K88 is a zoonotic pathogen. Previous studies have shown that lactic acid bacteria (LAB) have great potential in promoting health and resisting pathogenic infections; however, relatively little research has been done on the Pediococcus genus of LAB. This study is aimed at explori...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/7340312

    authors: Tan K,Deng D,Ma X,Cui Y,Tian Z

    更新日期:2020-03-30 00:00:00

  • Optimal Experiment Design for Monoexponential Model Fitting: Application to Apparent Diffusion Coefficient Imaging.

    abstract::The monoexponential model is widely used in quantitative biomedical imaging. Notable applications include apparent diffusion coefficient (ADC) imaging and pharmacokinetics. The application of ADC imaging to the detection of malignant tissue has in turn prompted several studies concerning optimal experiment design for ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/138060

    authors: Alipoor M,Maier SE,Gu IY,Mehnert A,Kahl F

    更新日期:2015-01-01 00:00:00

  • A redox-sensitive micelle-like nanoparticle self-assembled from amphiphilic adriamycin-human serum albumin conjugates for tumor targeted therapy.

    abstract::The application of chemotherapeutic drug adriamycin (ADR) in cancer therapy is limited by its side effects like high toxicity and insolubility. Nanomedicine offers new hope for overcoming the shortcomings. But how to increase in vivo stability and to control intracellular drug release is a key issue for nano-based for...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/987404

    authors: Chen L,Chen F,Zhao M,Zhu X,Ke C,Yu J,Yan Z,Zhang F,Sun Y,Chen D,Jiang C,Zhao X,Gao Y,Guo S,Li W

    更新日期:2015-01-01 00:00:00

  • Dexmedetomidine Attenuates Lipopolysaccharide Induced MCP-1 Expression in Primary Astrocyte.

    abstract::Background. Neuroinflammation which presents as a possible mechanism of delirium is associated with MCP-1, an important proinflammatory factor which is expressed on astrocytes. It is known that dexmedetomidine (DEX) possesses potent anti-inflammatory properties. This study aimed to investigate the potential effects of...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/6352159

    authors: Liu H,Davis JR,Wu ZL,Faez Abdelgawad A

    更新日期:2017-01-01 00:00:00

  • Effects of supplemental oxygen on maternal and neonatal oxygenation in elective cesarean section under spinal anesthesia: a randomized controlled trial.

    abstract::The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. The aim of this study was to determine the benefits for both mother and infant of administering supplemental, low-dose oxygen via a nasal cannula versus having no suppleme...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2014/627028

    authors: Siriussawakul A,Triyasunant N,Nimmannit A,Ngerncham S,Hirunkanokpan P,Luang-Aram S,Pechpaisit N,Wangdee A,Ruangvutilert P

    更新日期:2014-01-01 00:00:00

  • Metabolic Comorbidities and Risk of Development and Severity of Drug-Induced Liver Injury.

    abstract::The incidence and rates of diagnosis of drug-induced liver injury (DILI) have been increasing in recent years as findings from basic research and the examination of clinical databases reveal information about the clinical course, etiology, and prognosis of this complex disease. The prevalence of metabolic comorbiditie...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2019/8764093

    authors: Li X,Gao P,Niu J

    更新日期:2019-08-18 00:00:00

  • Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects.

    abstract::Upon allergen challenge, DC subsets are recruited to target sites under the influence of chemotactic agents; however, details pertinent to their trafficking remain largely unknown. We investigated the kinetic profiles of blood and skin-infiltrating DC subsets in twelve atopic subjects receiving six weekly intradermal ...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/231036

    authors: Vittorakis S,Samitas K,Tousa S,Zervas E,Aggelakopoulou M,Semitekolou M,Panoutsakopoulou V,Xanthou G,Gaga M

    更新日期:2014-01-01 00:00:00

  • Incidence of alpha-globin gene defect in the Lebanese population: a pilot study.

    abstract:BACKGROUND:It is well established that the Mediterranean and Arab populations are at high risk for thalassemias in general and for alpha-thalassemia in particular. Yet, reports on alpha-thalassemia in Lebanon are still lacking. In this study, we aim at assessing the incidence of alpha-thalassemia in the Lebanese popula...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/517679

    authors: Farra C,Daher R,Badra R,el Rafei R,Bejjany R,Charafeddine L,Yunis K

    更新日期:2015-01-01 00:00:00

  • Pathologic Assessment of Rectal Carcinoma after Neoadjuvant Radio(chemo)therapy: Prognostic Implications.

    abstract::Neoadjuvant radio(chemo)therapy is increasingly used in rectal cancer and induces a number of morphologic changes that affect prognostication after curative surgery, thereby creating new challenges for surgical pathologists, particularly in evaluating morphologic changes and tumour response to preoperative treatment. ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/574540

    authors: Hav M,Libbrecht L,Ferdinande L,Geboes K,Pattyn P,Cuvelier CA

    更新日期:2015-01-01 00:00:00

  • A fast, reliable, and sensitive method for detection and quantification of Listeria monocytogenes and Escherichia coli O157:H7 in ready-to-eat fresh-cut products by MPN-qPCR.

    abstract::In the present work we developed a MPN quantitative real-time PCR (MPN-qPCR) method for a fast and reliable detection and quantification of Listeria monocytogenes and Escherichia coli O157:H7 in minimally processed vegetables. In order to validate the proposed technique, the results were compared with conventional MPN...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/608296

    authors: Russo P,Botticella G,Capozzi V,Massa S,Spano G,Beneduce L

    更新日期:2014-01-01 00:00:00

  • Snake venom L-amino acid oxidases: trends in pharmacology and biochemistry.

    abstract::L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is primarily due to enzymatic activity, but other mechanisms have been proposed recently which require further investigation. L-amino acid oxidases ex...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/196754

    authors: Izidoro LF,Sobrinho JC,Mendes MM,Costa TR,Grabner AN,Rodrigues VM,da Silva SL,Zanchi FB,Zuliani JP,Fernandes CF,Calderon LA,Stábeli RG,Soares AM

    更新日期:2014-01-01 00:00:00

  • Mechanical and Histological Effects of Resorbable Blasting Media Surface Treatment on the Initial Stability of Orthodontic Mini-Implants.

    abstract::Introduction. This study aimed to evaluate the effects of resorbable blasting media (RBM) treatment on early stability of orthodontic mini-implants by mechanical, histomorphometric, and histological analyses. Methods. Ninety-six (64 for mechanical study and 32 for histological study and histomorphometric analysis) tit...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/7520959

    authors: Gansukh O,Jeong JW,Kim JW,Lee JH,Kim TW

    更新日期:2016-01-01 00:00:00

  • How to Stimulate Myocardial Regeneration in Adult Mammalian Heart: Existing Views and New Approaches.

    abstract::Stem cell-based therapy has been considered as a promising option in the treatment of ischemic heart disease. Although stem cell administration resulted in the temporary improvement of myocardial contractility in the majority of studies, the formation of new cardiomyocytes within the injured myocardium has not been co...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/7874109

    authors: Belostotskaya G,Hendrikx M,Galagudza M,Suchkov S

    更新日期:2020-03-03 00:00:00

  • The Effect of Immigration on Adverse Perinatal Outcomes: Analysis of Experiences at a Turkish Tertiary Hospital.

    abstract:Introduction:In literature, it is well documented that migration is associated with adverse perinatal outcomes in many countries over the world. But in Turkey, health care providers and obstetricians had to face the effects of migration for the first time after civil war in Syria. Hence, this situation motivated us to ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/2326797

    authors: Col Madendag I,Eraslan Sahin M,Madendag Y,Sahin E,Demir MB,Ozdemir F,Acmaz G,Muderris II

    更新日期:2019-11-05 00:00:00

  • Early Detection of Undiagnosed Hypertension Based on Occupational Screening in the Hotel and Restaurant Industry.

    abstract::Blood pressure is the most important, modifiable risk factor for cardiovascular diseases. Lifestyle factors and also workload are the main, potential risk factors for the development of hypertension. This study focused on the early detection of unknown hypertension by screening employees in the hotel and restaurant in...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/6820160

    authors: Seibt R,Hunger B,Stieler L,Stoll R,Kreuzfeld S

    更新日期:2018-04-08 00:00:00

  • A meta-analysis strategy for gene prioritization using gene expression, SNP genotype, and eQTL data.

    abstract::In order to understand disease pathogenesis, improve medical diagnosis, or discover effective drug targets, it is important to identify significant genes deeply involved in human disease. For this purpose, many earlier approaches attempted to prioritize candidate genes using gene expression profiles or SNP genotype da...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2015/576349

    authors: Che J,Shin M

    更新日期:2015-01-01 00:00:00

  • Robust Individual-Cell/Object Tracking via PCANet Deep Network in Biomedicine and Computer Vision.

    abstract::Tracking individual-cell/object over time is important in understanding drug treatment effects on cancer cells and video surveillance. A fundamental problem of individual-cell/object tracking is to simultaneously address the cell/object appearance variations caused by intrinsic and extrinsic factors. In this paper, in...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8182416

    authors: Zhong B,Pan S,Wang C,Wang T,Du J,Chen D,Cao L

    更新日期:2016-01-01 00:00:00

  • The Physical Activity Type Most Related to Cognitive Function and Quality of Life.

    abstract:Background:Physical activity has been found to maintain and improve cognitive function and consequently improve health-related quality of life (HRQoL). The relationships between different types of physical activities, cognitive function, and HRQoL have not been studied sufficiently and compared in different age and gen...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8856284

    authors: Alsubaie SF,Alkathiry AA,Abdelbasset WK,Nambi G

    更新日期:2020-12-18 00:00:00

  • Impact of Moderate Heat, Carvacrol, and Thymol Treatments on the Viability, Injury, and Stress Response of Listeria monocytogenes.

    abstract::The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/548930

    authors: Guevara L,Antolinos V,Palop A,Periago PM

    更新日期:2015-01-01 00:00:00