A redox-sensitive micelle-like nanoparticle self-assembled from amphiphilic adriamycin-human serum albumin conjugates for tumor targeted therapy.

abstract：:[This corrects the article DOI: 10.1155/2012/853879.]. ...

journal_title：BioMed research international

authors： Shirasu N,Yamada H,Shibaguchi H,Kuroki M,Kuroki M

更新日期：2015-01-01 00:00:00

abstract：:The role of non-steroidal anti-inflammatory drugs in inflammatory bowel disease is controversial, as they have been implicated in disease aggravation. Different from other cyclooxygenase inhibitors, acetylsalicylic acid (ASA) enhances the formation of anti-inflammatory and proresolution lipoxins derived from arachidon...

journal_title：BioMed research international

authors： Köhnke T,Gomolka B,Bilal S,Zhou X,Sun Y,Rothe M,Baumgart DC,Weylandt KH

更新日期：2013-01-01 00:00:00

abstract：:Calcium phosphate cement (CPC) has good release efficiency and has therefore been used as a drug delivery system for postoperative infection. The release profile of CPC has mainly been evaluated by in vitro studies, which are carried out by immersing test specimens in a relatively large amount of solvent. However, it ...

journal_title：BioMed research international

authors： Uchida K,Sugo K,Nakajima T,Nakawaki M,Takano S,Nagura N,Takaso M,Urabe K

更新日期：2018-05-15 00:00:00

abstract：:The aim of this study was to develop a freeze-drying protocol facilitating successful processing of plant material containing the small surface antigen of hepatitis B virus (S-HBsAg) while preserving its VLP structure and immunogenicity. Freeze-drying of the antigen in lettuce leaf tissue, without any isolation or pur...

journal_title：BioMed research international

authors： Czyż M,Dembczyński R,Marecik R,Wojas-Turek J,Milczarek M,Pajtasz-Piasecka E,Wietrzyk J,Pniewski T

更新日期：2014-01-01 00:00:00

abstract：Result:In the denture wearers, HHV8 DNA was detected in 11 cases. Two of the controls amplified HHV8 DNA. Fisher's exact test demonstrates a significant difference between virus infection and using removable dentures (p = 0.015). Conclusion:Our findings suggested that HHV8 detection could be associated with use of den...

journal_title：BioMed research international

authors： Derafshi R,Ghapanchi J,Rezazadeh F,Kalantari MH,Naeeni AM,Farzin M,Moattari A

更新日期：2020-04-15 00:00:00

abstract：:The search for effective methods of myocardial cytoprotection against ischemia is the most significant issue in modern cardiology and cardiac surgery. Glucocorticoids are deemed very strong modulators of inflammatory response and thus can potentially protect heart muscle from postreperfusion injury and myocardial isch...

journal_title：BioMed research international

authors： Kuropka P,Dobrzyński M,Gamian A,Gostomska-Pampuch K,Kuryszko J,Całkosiński I

更新日期：2017-01-01 00:00:00

abstract：:Sulfated polysaccharides (GSP) were isolated from the cloned Grateloupia filicina which was cultured in Jiaozhou Bay, Qingdao, China. The yield of GSP was 15.75%. The total sugar and sulfate were 40.90 and 19.89%, respectively. And the average molecular weight was 11.7 KDa. The results of neutral sugar analysis showed...

journal_title：BioMed research international

authors： Chen X,Yang S,Wang J,Song L,Xing R,Liu S,Yu H,Li P

更新日期：2015-01-01 00:00:00

abstract：:DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu elements is an impor...

journal_title：BioMed research international

authors： Luo Y,Lu X,Xie H

更新日期：2014-01-01 00:00:00

abstract：:Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour. Moreover this is a heterogeneous disease based on the tissue of origin. As CT7 and CT10 are highly expressed in cutaneous melanoma and are immunogenic in this disease, we analysed their expressi...

journal_title：BioMed research international

authors： Curioni-Fontecedro A,Pitocco R,Schoenewolf NL,Holzmann D,Soldini D,Dummer R,Calvieri S,Moch H,Mihic-Probst D,Fitsche A

更新日期：2015-01-01 00:00:00

abstract：:The efficiency of oat bran and barley bran in lowering the induced hyperlipidemia and hypercholesterolemia in blood of male Albino rats (Rattus rattus) was studied. Twenty rats were divided into four groups each consisted of five rats and fed the specified test diets for eight weeks. The first group (G1) is the negati...

journal_title：BioMed research international

authors： El Rabey HA,Al-Seeni MN,Amer HM

更新日期：2013-01-01 00:00:00

abstract：:The administration of probiotic bacteria for health benefit has rapidly expanded in recent years, with a global market worth $32.6 billion predicted by 2014. The oral administration of most of the probiotics results in the lack of ability to survive in a high proportion of the harsh conditions of acidity and bile conc...

journal_title：BioMed research international

authors： Solanki HK,Pawar DD,Shah DA,Prajapati VD,Jani GK,Mulla AM,Thakar PM

更新日期：2013-01-01 00:00:00

abstract：:Cabbages (Brassica oleracea L.) are an important vegetable crop around world, and cold temperature is among the most significant abiotic stresses causing agricultural losses, especially in cabbage crops. Plant bZIP transcription factors play diverse roles in biotic/abiotic stress responses. In this study, 119 putative...

journal_title：BioMed research international

authors： Hwang I,Manoharan RK,Kang JG,Chung MY,Kim YW,Nou IS

更新日期：2016-01-01 00:00:00

abstract：:Infective endocarditis (IE) is a life-threatening disease that is associated with high morbidity and mortality. Its long-term prognosis strongly depends on a timely and optimized antibiotic treatment. Therefore, identification of the causative pathogen is crucial and currently based on blood cultures followed by chara...

journal_title：BioMed research international

authors： Maneg D,Sponsel J,Müller I,Lohr B,Penders J,Madlener K,Hunfeld KP

更新日期：2016-01-01 00:00:00

abstract：:Patients with clinical suspicion of large-vessel vasculitis (LVV) may present with nonspecific signs and symptoms and increased inflammatory parameters and may remain without diagnosis after routine diagnostic procedures. Both the nonspecificity of the radiopharmaceutical (18)F-FDG and the synergy of integrating funct...

journal_title：BioMed research international

authors： Balink H,Bennink RJ,van Eck-Smit BL,Verberne HJ

更新日期：2014-01-01 00:00:00

abstract：Background and Aim:Lubiprostone is a novel laxative that sometimes causes nausea, but preventive strategies remain unconfirmed. Methods:We retrospectively chose 126 patients prescribed lubiprostone from 2013 to 2016. Medical records were reviewed to clarify whether nausea developed after administration of the drug. Ba...

journal_title：BioMed research international

authors： Yamamoto T,Osumi S,Yanagisawa D,Yamato H,Aoyagi H,Isono A,Abe K,Kita H

更新日期：2017-01-01 00:00:00

abstract：:Uraemia and long-term peritoneal dialysis (PD) can lead to fibrotic thickening of the peritoneal membrane, which may limit its dialytic function. Peritoneal fibrosis is associated with the appearance of myofibroblasts and expansion of extracellular matrix. The extent of contribution of resident peritoneal fibroblasts ...

journal_title：BioMed research international

authors： Witowski J,Kawka E,Rudolf A,Jörres A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Primary malignant spine/spinal tumors (PMSTs) are rare and life-threatening diseases. In this study, we demonstrated the advantage of volume-based 18F-FDG PET/CT metabolic parameter, metabolic tumor volume (MTV), for assessing the aggressiveness of PMSTs. MATERIALS AND METHODS:We retrospectively...

journal_title：BioMed research international

authors： Matsumoto Y,Baba S,Endo M,Setsu N,Iida K,Fukushi JI,Kawaguchi K,Okada S,Bekki H,Isoda T,Kitamura Y,Honda H,Nakashima Y

更新日期：2017-01-01 00:00:00

abstract：:Background. Aortic valve calcification (AVC) is a common feature of aging and is related to coronary artery disease. Although abdominal visceral adipose tissue (VAT) plays fundamental roles in coronary artery disease, the relationship between abdominal VAT and AVC is not fully understood. Methods. We investigated 259 ...

journal_title：BioMed research international

authors： Oikawa M,Owada T,Yamauchi H,Misaka T,Machii H,Yamaki T,Sugimoto K,Kunii H,Nakazato K,Suzuki H,Saitoh S,Takeishi Y

更新日期：2016-01-01 00:00:00

abstract：:Lung cancer is one of the leading triggers for cancer death worldwide. In this study, the relationship of the aberrantly methylated and differentially expressed genes in lung adenocarcinoma (LUAD) with cancer prognosis was investigated, and 5 feature genes were identified eventually. Specifically, we firstly downloade...

journal_title：BioMed research international

authors： Wang X,Shi D,Zhao D,Hu D

更新日期：2020-09-25 00:00:00

abstract：:With the increasing demand for noninvasive approaches in monitoring head and neck cancer, circulating nucleic acids have been shown to be a promising tool. We focused on the global transcriptome of serum samples of head and neck squamous cell carcinoma (HNSCC) patients in comparison with healthy individuals. We compar...

journal_title：BioMed research international

authors： Čapková M,Šáchová J,Strnad H,Kolář M,Hroudová M,Chovanec M,Čada Z,Šteffl M,Valach J,Kastner J,Vlček Č,Smetana K Jr,Plzák J

更新日期：2014-01-01 00:00:00

abstract：Objectives:Childhood malnutrition is major health concern in many low- and middle-income countries, including Vietnam. It was a major risk factor for child mortality and adult ill-health. Malnutrition could increase the risk of serious infections; conversely current diseases also had a negative impact on the growth of ...

journal_title：BioMed research international

authors： Huynh G,Huynh QHN,Nguyen NHT,Do QT,Khanh Tran V

更新日期：2019-02-05 00:00:00

abstract：:Since proteins carry out their functions through interactions with other molecules, accurately identifying the protein-ligand binding site plays an important role in protein functional annotation and rational drug discovery. In the past two decades, a lot of algorithms were present to predict the protein-ligand bindin...

journal_title：BioMed research international

authors： Wang K,Gao J,Shen S,Tuszynski JA,Ruan J,Hu G

更新日期：2013-01-01 00:00:00

abstract：:Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...

journal_title：BioMed research international

authors： Bit A,Ghagare D,Rizvanov AA,Chattopadhyay H

更新日期：2017-01-01 00:00:00

abstract：:Gold nanorods (GNRs) are considered one of the most promising forms of nanoparticles for nanobiotechnology; however, the problem of their toxicity is currently not resolved. We synthesised GNRs, modified with linear polyethyleneimine (PEI-GNRs), and examined their physicochemical and some biological properties in comp...

journal_title：BioMed research international

authors： Pyshnaya IA,Razum KV,Poletaeva JE,Pyshnyi DV,Zenkova MA,Ryabchikova EI

更新日期：2014-01-01 00:00:00

abstract：:Whole body vibration (WBV) has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS). To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE-/-) AS mice, which were trained by WBV (15 Hz, 30 m...

journal_title：BioMed research international

authors： Wu H,Zhang Y,Yang X,Li X,Shao Z,Zhou Z,Li Y,Pan S,Liu C

更新日期：2018-03-07 00:00:00

abstract：:Angiopoietin-like protein 4 (ANGPTL4) is widely known as a key regulator of lipid metabolism. We investigated the relationship between ANGPTL4 expression in serum or urine and blood lipid or urine protein levels of patients with hyperlipidemia- (HL-) related proteinuria. Sixty-eight patients with HL-related proteinuri...

journal_title：BioMed research international

authors： Gao X,Zhang M,Feng W,Xu Z,Wang Y,Shi L,Zhang J

更新日期：2020-03-23 00:00:00

abstract：Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...

journal_title：BioMed research international

authors： Hsu YY,Bai CH,Yang CM,Huang YC,Lin TT,Lin CH

更新日期：2019-06-23 00:00:00

abstract：:Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory property, the present study performed Gene Ontology and Ingenuity Pathway Analysis (IPA) to describe the basic g...

journal_title：BioMed research international

authors： Li T,Zhu J,Deng F,Wu W,Zheng Z,Lv C,Li Y,Xiang W,Lu X,Qin S

更新日期：2019-03-07 00:00:00

abstract：:Hepatitis B virus- (HBV-) associated hepatocellular carcinoma (HCC) is the most common type of liver cancer. However, the underlying mechanism of HCC tumorigenesis is very complicated and HBV-encoded X protein (HBx) has been reported to play the most important role in this process. Activation of downstream signal path...

journal_title：BioMed research international

authors： Hung CM,Huang WC,Pan HL,Chien PH,Lin CW,Chen LC,Chien YF,Lin CC,Leow KH,Chen WS,Chen JY,Ho CY,Hou PS,Chen YJ

更新日期：2014-01-01 00:00:00

abstract：:Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease, which manifests as a succession of outbreaks. OLP was associated with salivary oxidative stress. Randomized, double blind, parallel-group study was performed. The sample consisted of 55 clinically and histopathologically diagnosed OLP patients. ...

journal_title：BioMed research international

authors： Tvarijonaviciute A,Aznar-Cayuela C,Rubio CP,Tecles F,Ceron JJ,López-Jornet P

更新日期：2018-05-27 00:00:00