The role of 18F-FDG PET/CT in large-vessel vasculitis: appropriateness of current classification criteria?

abstract：:Protein structure prediction (PSP) is computationally a very challenging problem. The challenge largely comes from the fact that the energy function that needs to be minimised in order to obtain the native structure of a given protein is not clearly known. A high resolution 20 × 20 energy model could better capture th...

journal_title：BioMed research international

authors： Rashid MA,Newton MA,Hoque MT,Sattar A

更新日期：2013-01-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) based on the ferritin heavy chain 1 (FTH1) reporter gene has been used to trace stem cells. However, whether FTH1 expression is affected by stem cell differentiation or whether cell differentiation is affected by reporter gene expression remains unclear. Here, we explore the relationsh...

journal_title：BioMed research international

authors： Mu T,Qin Y,Liu B,He X,Liao Y,Sun J,Qiu J,Li X,Zhong Y,Cai J

更新日期：2018-06-26 00:00:00

abstract：:The availability of fluorescent dyes and the advances in the optical systems for in vivo imaging have stimulated an increasing interest in developing new methodologies to study and quantify the biodistribution of labeled agents. However, despite these great achievements, we are facing significant challenges in determi...

journal_title：BioMed research international

authors： Munisso MC,Yamaoka T

更新日期：2014-01-01 00:00:00

abstract：Objective:To investigate the prevalence of infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) among ICU admission patients in central China and develop a reliable prediction model. Methods:Five hundred and seven consecutive ICU admission patients with Klebsiella pneumoniae (KP) infection were enrolled...

journal_title：BioMed research international

authors： Li Y,Shen H,Zhu C,Yu Y

更新日期：2019-03-27 00:00:00

abstract：:Several intestinal parasites of baboons are of zoonotic importance, especially where there is considerable interaction between the baboons and humans. The identification of gastrointestinal parasite infections of baboons (Papio anubis) was undertaken at the Shai Hills Reserve Resort, Ghana. A total of 51 faecal sample...

journal_title：BioMed research international

authors： Larbi JA,Akyeampong S,Abubakari A,Offei Addo S,Okoto D,Hanson H

更新日期：2020-03-11 00:00:00

abstract：INTRODUCTION:Severe sepsis and septic shock are the primary causes of multiple organ dysfunction syndrome (MODS), which is the most frequent cause of death in intensive care unit patients. Many pro- and anti-inflammatory mediators, such as interleukin-6 (IL-6), play a strategic role in septic syndrome. Continuous renal...

journal_title：BioMed research international

authors： Servillo G,Vargas M,Pastore A,Procino A,Iannuzzi M,Capuano A,Memoli A,Riccio E,Memoli B

更新日期：2013-01-01 00:00:00

abstract：:Q192R and L55M polymorphism were considered to be associated with the development of multiple cancers. Nevertheless, the results of these researches were inconclusive and controversial. Therefore, we conducted a meta-analysis of all eligible case-control studies to assess the association between PON1 (Q192R and L55M) ...

journal_title：BioMed research international

authors： Pan X,Huang L,Li M,Mo D,Liang Y,Liu Z,Huang Z,Huang L,Liu J,Zhu B

更新日期：2019-07-28 00:00:00

abstract：:Epigenetic changes have major role in the normal development and programming of gene expression. Aberrant methylation results in carcinogenesis. The primary objective of our study is to determine whether primary tumor tissue and cultured tumor cells in 2D and 3D tissue culture systems have the same methylation signatu...

journal_title：BioMed research international

authors： Şükrüoğlu Erdoğan Ö,Kılıç Erciyas S,Bilir A,Buğra Tunçer Ş,Akdeniz Ödemiş D,Kurul S,Karanlık H,Cabıoğlu N,Yazıcı H

更新日期：2019-01-17 00:00:00

abstract：:Gravity is crucial for spatial perception, postural equilibrium, and movement generation. The vestibular apparatus is the main sensory system involved in monitoring gravity. Hair cells in the vestibular maculae respond to gravitoinertial forces, but they cannot distinguish between linear accelerations and changes of h...

journal_title：BioMed research international

authors： Lacquaniti F,Bosco G,Gravano S,Indovina I,La Scaleia B,Maffei V,Zago M

更新日期：2014-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...

journal_title：BioMed research international

authors： Guo L,Wang D,Ouyang X,Tang N,Chen X,Zhang Y,Zhu H,Li X

更新日期：2018-12-26 00:00:00

abstract：:Birt-Hogg-Dube syndrome (BHD, OMIM#135150) is a rare disease in clinic; it is characterized by skin fibrofolliculomas, pulmonary cysts with an increased risk of recurrent pneumothorax, renal cysts, and renal neoplasms. Previous studies have demonstrated that variants in folliculin (FLCN, NM_144997) are mainly responsi...

journal_title：BioMed research international

authors： Liu L,Yang K,Wang X,Shi Z,Yang Y,Yuan Y,Guo T,Xiao X,Luo H

更新日期：2017-01-01 00:00:00

abstract：:Big data bioinformatics aims at drawing biological conclusions from huge and complex biological datasets. Added value from the analysis of big data, however, is only possible if the data is accompanied by accurate metadata annotation. Particularly in high-throughput experiments intelligent approaches are needed to kee...

journal_title：BioMed research international

authors： Friedrich A,Kenar E,Kohlbacher O,Nahnsen S

更新日期：2015-01-01 00:00:00

abstract：:Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date. 70 patients with severe mitral regurgitation, additional pulmonary hy...

journal_title：BioMed research international

authors： Hünlich M,Lubos E,Beuthner BE,Puls M,Bleckmann A,Beißbarth T,Tichelbäcker T,Rudolph V,Baldus S,Schäfer U,Treede H,Von Bardeleben RS,Blankenberg S,Schillinger W

更新日期：2018-03-14 00:00:00

abstract：:The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular...

journal_title：BioMed research international

authors： Yang M,Sheng L,Zhang TR,Li Q

更新日期：2013-01-01 00:00:00

abstract：:Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...

journal_title：BioMed research international

authors： Veryser L,Bracke N,Wynendaele E,Joshi T,Tatke P,Taevernier L,De Spiegeleer B

更新日期：2016-01-01 00:00:00

abstract：:Cancer treatment is undergoing a significant revolution from "one-size-fits-all" cytotoxic therapies to tailored approaches that precisely target molecular alterations. Precision strategies for drug development and patient stratification, based on the molecular features of tumors, are the next logical step in a long h...

journal_title：BioMed research international

authors： Coyle KM,Boudreau JE,Marcato P

更新日期：2017-01-01 00:00:00

abstract：Objectives:The mortality rate of patients with acute respiratory distress syndrome (ARDS) is high. Hence, it is crucial to identify a reliable biomarker with wide clinical applications for predicting the prognosis of patients with ARDS. This systematic review and meta-analysis was conducted to investigate the value of ...

journal_title：BioMed research international

authors： Ni Q,Li C,Lin H

更新日期：2020-04-05 00:00:00

abstract：:With the recent advancement in the field of ocular therapy, drug delivery approaches have been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the ability to deliver the therapeutic agent to a patient in a staggered profile. However the major drawbacks of the conventional drug deliv...

journal_title：BioMed research international

authors： Sahoo RK,Biswas N,Guha A,Sahoo N,Kuotsu K

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to find out the ideal cut-off level of phosphate for safe healing when deformity correction and concomitant lengthening are indicated in the two different skeletal maturity groups of patients with rickets. Thirty-nine hypophosphatemic rickets patients were selected for the study and were divi...

journal_title：BioMed research international

authors： Song SH,Lee H,Jeong JM,Cho WI,Kim SE,Song HR

更新日期：2014-01-01 00:00:00

abstract：:Objectives. Lung ultrasonography (LUS) is a useful examination to identify lung problems. Unfortunately, there are currently no LUS educational programs for medical students. We designed a brief LUS training course for medical students during the ED rotation. The purpose of training was improving cognitive and psychom...

journal_title：BioMed research international

authors： Lim JS,Lee S,Do HH,Oh KH

更新日期：2017-01-01 00:00:00

abstract：:Primary cilia are organelles protruding from cell surface into environment that function in regulating cell cycle and modulating cilia-related signal. Primary ciliogenesis and autophagy play important roles in tumorigenesis. However, the functions and interactions between primary cilia and autophagy in hepatocellular ...

journal_title：BioMed research international

authors： Liu L,Sheng JQ,Wang MR,Gan Y,Wu XL,Liao JZ,Tian DA,He XX,Li PY

更新日期：2019-10-02 00:00:00

abstract：:Breast cancer is the leading cause of death in women worldwide. The search for novel compounds with antitumor activity, with less adverse effects and higher efficacy, and the development of methods to evaluate their toxicity is an area of intense research. In this study we implemented the preparation and culture of br...

journal_title：BioMed research international

authors： Carranza-Torres IE,Guzmán-Delgado NE,Coronado-Martínez C,Bañuelos-García JI,Viveros-Valdez E,Morán-Martínez J,Carranza-Rosales P

更新日期：2015-01-01 00:00:00

abstract：:The anaerobic skin commensal Propionibacterium acnes is an underestimated cause of human infections and clinical conditions. Previous studies have suggested a role for the bacterium in lumbar disc herniation and infection. To further investigate this, five biopsy samples were surgically excised from each of 64 patient...

journal_title：BioMed research international

authors： Rollason J,McDowell A,Albert HB,Barnard E,Worthington T,Hilton AC,Vernallis A,Patrick S,Elliott T,Lambert P

更新日期：2013-01-01 00:00:00

abstract：:We compared the performances of 3 Multiple Allergen Simultaneous Test (MAST) assays: RIDA Allergy Screen (R-Biopharm, Darmstadt, Germany), MAST Optigen allergy system (Hitachi Chemical Diagnostics, Mountain View, CA), and Polycheck Allergy (Biocheck GmbH, Munster, Germany). Forty sera that tested positive with the RID...

journal_title：BioMed research international

authors： Han M,Shin S,Park H,Park KU,Park MH,Song EY

更新日期：2013-01-01 00:00:00

abstract：:Objectives. This study aimed to determine the feasibility of cochlear implantation for sensorineural hearing loss in patients with Waardenburg syndrome. Method. A retrospective chart review was performed on patients who underwent cochlear implantation at the University of Tokyo Hospital. Clinical classification, genet...

journal_title：BioMed research international

authors： Koyama H,Kashio A,Sakata A,Tsutsumiuchi K,Matsumoto Y,Karino S,Kakigi A,Iwasaki S,Yamasoba T

更新日期：2016-01-01 00:00:00

abstract：:Purpose. Kawasaki disease (KD) is a systemic vasculitis and is a leading cause of coronary artery lesions (CALs) in childhood. Our previous study has shown higher levels of serum Resistin in KD patients with coronary aneurysm. This study aimed at examining the association of Resistin with inflammatory cytokine express...

journal_title：BioMed research international

authors： Gao F,Si F,Feng S,Yi Q,Liu R

更新日期：2016-01-01 00:00:00

abstract：UNLABELLED:The aim of the study was to determine the effect of different muscle length and visual feedback information (VFI) on accuracy of isometric contraction of elbow flexors in men after an ischemic stroke (IS). MATERIALS AND METHODS:Maximum voluntary muscle contraction force (MVMCF) and accurate determinate musc...

journal_title：BioMed research international

authors： Juodzbaliene V,Darbutas T,Skurvydas A,Brazaitis M

更新日期：2016-01-01 00:00:00

abstract：:Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells. While numerous SL...

journal_title：BioMed research international

authors： Li XJ,Mishra SK,Wu M,Zhang F,Zheng J

更新日期：2014-01-01 00:00:00

abstract：Objectives:This study aims to determine the changing in hip anatomy parameters with age and reveals the reason for the extorsion of lower extremity in the aged. Design:Retrospective study. Participants:One hundred and forty patients who had received imaging check of the femur and acetabulum between October 2013 and O...

journal_title：BioMed research international

authors： Yin Y,Zhang R,Jin L,Li S,Hou Z,Zhang Y

更新日期：2018-09-27 00:00:00

abstract：:Several studies suggested that migraine attack onset shows a circadian variation; however, there has not been an overview and synthesis of these findings. A PubMed search with keywords "migraine" AND "circadian" resulted in ten studies directly investigating this topic. Results of these studies mostly show that migrai...

journal_title：BioMed research international

authors： Baksa D,Gecse K,Kumar S,Toth Z,Gal Z,Gonda X,Juhasz G

更新日期：2019-08-25 00:00:00