Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure.

abstract：:The relationship between oxidative stress and miRNA changes in placenta as a potential mechanism involved in preeclampsia (PE) is not fully elucidated. We investigated the impact of oxidative stress on miRNAs and mRNA expression profiles of genes associated with PE in villous 3A first trimester trophoblast cells expos...

journal_title：BioMed research international

authors： Cross CE,Tolba MF,Rondelli CM,Xu M,Abdel-Rahman SZ

更新日期：2015-01-01 00:00:00

abstract：:This study evaluated the presence of Acanthamoeba species in the Puzih River watershed, which features typical subtropical monsoon climate and is located just above the Tropic of Cancer in Taiwan. The relationship between the seasonal and geographical distributions of Acanthamoeba species in this rivershed was also in...

journal_title：BioMed research international

authors： Kao PM,Chou MY,Tao CW,Huang WC,Hsu BM,Shen SM,Fan CW,Chiu YC

更新日期：2013-01-01 00:00:00

abstract：:The primary goal of this work was to study advantages of numerical methods used for the creation of continuous time Markov chain models (CTMC) of voltage gating of gap junction (GJ) channels composed of connexin protein. This task was accomplished by describing gating of GJs using the formalism of the stochastic autom...

journal_title：BioMed research international

authors： Snipas M,Pranevicius H,Pranevicius M,Pranevicius O,Paulauskas N,Bukauskas FF

更新日期：2015-01-01 00:00:00

abstract：:Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded as an absolute or r...

journal_title：BioMed research international

authors： Lee W,Kim Y,Choi H,Kim H,Lee S,Lee H,Chee H,Kim J,Hwang J,Lee S,Kim Y,Cho S,Ryu S,Park S

更新日期：2017-01-01 00:00:00

abstract：:Type 1 diabetes (T1D), a chronic autoimmune disease, is often preceded by a preclinical phase of islet autoimmunity (IA) where the insulin-producing beta cells of the pancreas are destroyed and circulating autoantibodies can be detected. The goal of this study was to demonstrate methods for identifying exposures that ...

journal_title：BioMed research international

authors： Frederiksen BN,Kroehl M,Barón A,Lamb MM,Crume TL,Sontag MK,Rewers M,Norris JM

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Electrical Bioimpedance Cerebral Monitoring is assessment in real time of health of brain tissue through study of passive dielectric properties of brain. During the last two decades theory and technology have been developed in parallel with animal experiments aiming to confirm feasibility of using bioimpedance-...

journal_title：BioMed research international

authors： Seoane F,Reza Atefi S,Tomner J,Kostulas K,Lindecrantz K

更新日期：2015-01-01 00:00:00

abstract：:Iodinated contrast (IC) is clinically used in diagnostic and interventional procedures, but its use can result in contrast-induced acute kidney injury (CI-AKI). Chronic kidney disease (CKD) and chronic hyperglycemia (CH) are important predisposing factors to CI-AKI. The aim of this study was to investigate the impact ...

journal_title：BioMed research international

authors： Fernandes SM,Martins DM,da Fonseca CD,Watanabe M,Vattimo Mde F

更新日期：2016-01-01 00:00:00

abstract：:MicroRNAs (miRs) are small noncoding RNA molecules and recently have demonstrated that altered expression and functions are their tight association with ulcerative colitis (UC). Previous microarray study reported that miR-214 was downregulated in the sigmoid colon of patients with active UC, but the roles of miR-214 i...

journal_title：BioMed research international

authors： Li JA,Wang YD,Wang K,Wang ZL,Jia DY,Yang BY,Xiong CB

更新日期：2017-01-01 00:00:00

abstract：Background:Inflammation is the major risk factor for the progression of hepatocellular carcinoma (HCC), and the nuclear factor-κB (NF-κB) signaling plays the central role in the inflammation process. However, the activated mechanism of NF-κB signaling in HCC is unclear. Methods:The expression of PHF5A is examined by q...

journal_title：BioMed research international

authors： Yang Q,Zhang J,Xu S,Jia C,Meng W,Tang H,Zhang X,Zhang Y,Fu B

更新日期：2019-01-15 00:00:00

abstract：:Bone marrow stromal cells (BMSCs) are a valuable resource for skeletal regenerative medicine because of their osteogenic potential. In spite of the very general term "stem cell," this population of cells is far from homogeneous, and different BMSCs clones have greatly different phenotypic properties and, therefore, po...

journal_title：BioMed research international

authors： Vianna VF,Bonfim DC,Cavalcanti Ados S,Fernandes MC,Kahn SA,Casado PL,Lima IC,Murray SS,Murray EJ,Duarte ME

更新日期：2013-01-01 00:00:00

abstract：:We review the recent literature concerning the efficiency of antimicrobial photodynamic inactivation toward various microbial species in planktonic and biofilm cultures. The review is mainly focused on biofilm-growing microrganisms because this form of growth poses a threat to chronically infected or immunocompromised...

journal_title：BioMed research international

authors： Taraszkiewicz A,Fila G,Grinholc M,Nakonieczna J

更新日期：2013-01-01 00:00:00

abstract：:We measured 28 parameters of 202 femurs from Koreans by an automated geometric computation program using 3D models generated from computed tomography images. The measurement parameters were selected with reference to physical and forensic anthropology studies as well as orthopedic implant design studies. All measureme...

journal_title：BioMed research international

authors： Cho HJ,Kwak DS,Kim IB

更新日期：2015-01-01 00:00:00

abstract：:Functional connectivity has been correlated with a patient's level of consciousness and has been found to be altered in several neuropsychiatric disorders. Absence epilepsy patients, who experience a loss of consciousness, are assumed to suffer from alterations in thalamocortical networks; however, previous studies ha...

journal_title：BioMed research international

authors： Xu CP,Zhang SW,Fang T,Manxiu M,Chencan Q,Huafu C,Zhu HW,Li YJ,Zuxiang L

更新日期：2013-01-01 00:00:00

abstract：:Diverse high energy diets have been utilized to precipitate obesity and related metabolic disorders in rodent models, though the dietary intervention has not absolutely been standardized. The present study established usage of a customized semipurified normal control diet (NCD) and high fat diet (HFD), for research st...

journal_title：BioMed research international

authors： Sasidharan SR,Joseph JA,Anandakumar S,Venkatesan V,Ariyattu Madhavan CN,Agarwal A

更新日期：2013-01-01 00:00:00

abstract：:Despite remarkable therapeutic advances have been made in the last few decades, non-small cell lung cancer (NSCLC) is still one of the leading causes of death worldwide. Brain metastases are a common complication of a wide range of human malignancies and in particular NSCLC. Brain-derived neurotrophic factor (BDNF), b...

journal_title：BioMed research international

authors： Lombardi M,D'Ascanio M,Scarpino S,Scozzi D,Giordano M,Costarelli L,Raj ER,Mancini R,Cardillo G,Cardaci V,Innammorato M,Vecchione A,Ricci A

更新日期：2020-11-17 00:00:00

abstract：:Rabbit hemorrhagic disease (RHD) is an acute, high fatal contagious disease induced by rabbit hemorrhagic disease virus (RHDV) with acute severe hepatic injury and causes huge economic loss worldwide. In order to develop an effective and reliable drug to treat this disease in clinic, a prescription formulated with bai...

journal_title：BioMed research international

authors： Du H,Zhang S,He M,Ming K,Wang J,Yuan W,Qiao M,Wu Y,Wang D,Hu Y,Liu J

更新日期：2019-04-04 00:00:00

abstract：:Sericin is a natural protein component of silks of silkworm and has potential utility in multiple areas such as pharmacological, cosmetics, and biotechnological industries. However, the understanding of its toxicological safety is still limited. This study evaluated the safety of water-extract sericin from silkworm (B...

journal_title：BioMed research international

authors： Qin H,Zhang J,Yang H,Yao S,He L,Liang H,Wang Y,Chen H,Zhao P,Qin G

更新日期：2020-11-05 00:00:00

abstract：:Our research investigates the serum levels of three angiogenic factors in the AF family, namely, placenta growth factor (PlGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF), in 54 patients with SLE (SLE group) and 28 healthy controls (normal control) through ELISA measurement. A...

journal_title：BioMed research international

authors： Zhou L,Lu G,Shen L,Wang L,Wang M

更新日期：2014-01-01 00:00:00

abstract：:The principle mechanism of protection of stem cells is through the expression of ATP-binding cassette (ABC) transporters. These transporters serve as the guardians of the stem cell population in the body. Unfortunately these very same ABC efflux pumps afford protection to cancer stem cells in tumors, shielding them fr...

journal_title：BioMed research international

authors： Moitra K

更新日期：2015-01-01 00:00:00

abstract：:Mild cognitive impairment (MCI) refers to a transitional state between normal aging and dementia and is a syndrome with cognitive decline greater than expected for an individual's age and educational level. As a subtype of MCI, amnestic mild cognitive impairment (aMCI) most often leads to Alzheimer's disease. This stu...

journal_title：BioMed research international

authors： Zhao Z,Lu J,Jia X,Chao W,Han Y,Jia J,Li K

更新日期：2014-01-01 00:00:00

abstract：:There is a controversial relationship between HLA-A2 and Alzheimer's disease (AD). It has been suggested a modifier effect on the risk that depends on genetic loadings. Thus, the aims of this study were to evaluate this relationship and to reveal genes associated with both concepts the HLA-A gene and AD. Consequently,...

journal_title：BioMed research international

authors： Cifuentes RA,Murillo-Rojas J

更新日期：2014-01-01 00:00:00

abstract：:Both human adipose tissue-derived mesenchymal stem cells (ASCs) and umbilical cord-derived mesenchymal stem cells (UC-MSCs) have been explored as attractive mesenchymal stem cells (MSCs) sources, but very few parallel comparative studies of these two cell types have been made. We designed a side-by-side comparative st...

journal_title：BioMed research international

authors： Hu L,Hu J,Zhao J,Liu J,Ouyang W,Yang C,Gong N,Du L,Khanal A,Chen L

更新日期：2013-01-01 00:00:00

abstract：:In recent years, new prognostic indexes (PIs) for chronic lymphocytic leukemia (CLL), which include clinical, biological, and genetic variables, have been validated, highlighting the MD Anderson Cancer Center prognostic index (MDACC PI), the CLL-international prognostic index (CLL-IPI), and the Barcelona-Brno biomarke...

journal_title：BioMed research international

authors： Muñoz-Novas C,Poza-Santaella M,González-Gascón Y Marín I,Hernández-Sánchez M,Rodríguez-Vicente AE,Infante MS,Heras C,Foncillas MÁ,Marín K,Hernández-Rivas JM,Hernández JÁ

更新日期：2018-03-15 00:00:00

abstract：:Tau tubulin kinase 2 (TTBK2) is a kinase known to phosphorylate tau and tubulin. It has recently drawn much attention due to its involvement in multiple important cellular processes. Here, we review the current understanding of TTBK2, including its sequence, structure, binding sites, phosphorylation substrates, and ce...

journal_title：BioMed research international

authors： Liao JC,Yang TT,Weng RR,Kuo CT,Chang CW

更新日期：2015-01-01 00:00:00

abstract：Purpose:Ischemic ocular disorders may be treated by hypervolemic hemodilution. The presumed therapeutic benefit is based on a volume effect and improved rheological factors. The aim was to investigate the acute effect of intravenous hydroxyethyl starch on retrobulbar hemodynamics in patients with nonarteritic anterior ...

journal_title：BioMed research international

authors： Bienert M,Plange N,Remky A,Arend KO,Kuerten D

更新日期：2018-02-06 00:00:00

abstract：:The objective of this study was the synthesis of folic acid- (FA-) targeted polymeric micelles of Synperonic PE/F 127-cholesteryl hemisuccinate (PF127-Chol) for specific delivery of docetaxel (DTX). Targeted or nontargeted micelles loaded with DTX were prepared via dialysis method. The effects of processing variables ...

journal_title：BioMed research international

authors： Varshosaz J,Taymouri S,Hassanzadeh F,Javanmard SH,Rostami M

更新日期：2015-01-01 00:00:00

abstract：:The insula is believed to be associated with touch-evoked effects. In this work, functional MRI was applied to investigate the network model of insula function when 20 normal subjects received tactile stimulation over segregated areas. Data analysis was performed with SPM8 and Conn toolbox. Activations in the contrala...

journal_title：BioMed research international

authors： Wei P,Bao R

更新日期：2013-01-01 00:00:00

abstract：:Human mesenchymal stem cells (MSCs) have an intrinsic property for homing towards tumor sites and can be used as tumor-tropic vectors for tumor therapy. But very limited studies investigated the antitumor properties of MSCs themselves. In this study we investigated the antiglioma properties of two easily accessible MS...

journal_title：BioMed research international

authors： Yang C,Lei D,Ouyang W,Ren J,Li H,Hu J,Huang S

更新日期：2014-01-01 00:00:00

abstract：:T. reesei is an efficient cellulase producer and biomass degrader. To improve xylitol production in Trichoderma reesei strains by genetic engineering, two approaches were used in this study. First, the presumptive D-xylulokinase gene in T. reesei (xyiH), which has high homology to known fungi D-xylulokinase genes, was...

journal_title：BioMed research international

authors： Hong Y,Dashtban M,Kepka G,Chen S,Qin W

更新日期：2014-01-01 00:00:00

abstract：:The establishment of the subgingival microbiota is dependent on successive colonization of the implant surface by bacterial species. Different implant surface topographies could influence the bacterial adsorption and therefore jeopardize the implant survival. This study evaluated the biofilm formation capacity of five...

journal_title：BioMed research international

authors： Pita PP,Rodrigues JA,Ota-Tsuzuki C,Miato TF,Zenobio EG,Giro G,Figueiredo LC,Gonçalves C,Gehrke SA,Cassoni A,Shibli JA

更新日期：2015-01-01 00:00:00