Development of microencapsulation delivery system for long-term preservation of probiotics as biotherapeutics agent.

abstract：:Aldosterone synthase (CYP11B2) is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS) and lead to hypertension. Therefore, research and development of CYP...

journal_title：BioMed research international

authors： Luo G,Lu F,Qiao L,Chen X,Li G,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:Human mesenchymal stem cells (MSCs) have an intrinsic property for homing towards tumor sites and can be used as tumor-tropic vectors for tumor therapy. But very limited studies investigated the antitumor properties of MSCs themselves. In this study we investigated the antiglioma properties of two easily accessible MS...

journal_title：BioMed research international

authors： Yang C,Lei D,Ouyang W,Ren J,Li H,Hu J,Huang S

更新日期：2014-01-01 00:00:00

abstract：:Tyrosine kinase inhibitors (TKI) belong to a new class of molecular multitargeted anticancer therapy which targets different growth factor receptors and hence attenuates cancer cell survival and growth. Since their introduction as adjunct treatment for renal cell carcinoma and gastrointestinal stromal tumors (GIST), a...

journal_title：BioMed research international

authors： Ahmadieh H,Salti I

更新日期：2013-01-01 00:00:00

abstract：Objective:Epidemiological studies have shown a correlation between periodontal disease (PD) and age-related macular degeneration (AMD). However, the results have been inconsistent, and no relevant meta-analysis has been performed on this topic. Hence, we performed a meta-analysis to evaluate whether the two diseases ar...

journal_title：BioMed research international

authors： Lv X,Li W,Fang Z,Xue X,Pan C

更新日期：2020-09-28 00:00:00

abstract：Methods:The implantation sites, fetus resorption, and abnormal fetuses were studied in pregnant mice treated with different doses of BaP by oral gavage from day 1 to day 10 of gestation. Additionally, apoptosis and related signaling pathway, and the migration and invasion of trophoblasts, were assessed before and after...

journal_title：BioMed research international

authors： Ye Y,Jiang S,Zhang C,Cheng Y,Zhong H,Du T,Xu W,Azziz R,Zhang H,Zhao X

更新日期：2020-10-16 00:00:00

abstract：Background:Neonatal jaundice is common a clinical problem worldwide. Globally, every year, about 1.1 million babies develop severe hyperbilirubinemia with or without bilirubin encephalopathy and the vast majority reside in sub-Saharan Africa and South Asia. Strategies and information on determinants of neonatal jaundic...

journal_title：BioMed research international

authors： Asefa GG,Gebrewahid TG,Nuguse H,Gebremichael MW,Birhane M,Zereabruk K,Zemicheal TM,Hailay A,Abrha WA,Hadera SA,Hailu AG,Beyene BH,Dagnazgi EA,Tekulu FG,Welay F

更新日期：2020-10-21 00:00:00

abstract：Objective:The aim of this study was to investigate the respective correlation between the height (H) of a posterior malleolar fracture (PMF) and the involved area (S) of an articular surface and the presence of "die-punch." Methods:Patients with closed posterior malleolar fractures admitted to our hospital from Januar...

journal_title：BioMed research international

authors： Wang Z,Yuan C,Zhu G,Geng X,Zhang C,Huang J,Ma X,Wang X

更新日期：2020-07-29 00:00:00

abstract：:This study aims to evaluate whether diets containing mixture of formic and propionic acid alone or supplemented with either capric acid or Bacillus Licheniformis can alleviate immune inflammatory response of piglets challenged with enterotoxigenic Escherichia coli (ETEC). A total of 30 weaning pigs were assigned to 5 ...

journal_title：BioMed research international

authors： Ren C,Zhou Q,Guan W,Lin X,Wang Y,Song H,Zhang Y

更新日期：2019-03-25 00:00:00

abstract：:Although multimodal therapies including surgery, chemotherapy, and radiotherapy have improved clinical outcomes of patients with bone and soft tissue sarcomas, the prognosis of patients has plateaued over these 20 years. Immunotherapies have shown the effectiveness for several types of advanced tumors. Immunotherapies...

journal_title：BioMed research international

authors： Uehara T,Fujiwara T,Takeda K,Kunisada T,Ozaki T,Udono H

更新日期：2015-01-01 00:00:00

abstract：:Poly(ADP-ribose) polymerase (PARP) inhibitors have proven to be successful agents in inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached clinical trial testing for treatment in different cancers, and, recently, Olaparib (AZD2281) has gained both United States Food and Drug Admini...

journal_title：BioMed research international

authors： Murata S,Zhang C,Finch N,Zhang K,Campo L,Breuer EK

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the shear displacement between the body and backrest/seat, range of motion (ROM), and force acting on the lower limb joints during sit-stand-sit transitions by operating an electric-powered standing wheelchair. METHODS AND MATERIALS:The amounts of sliding along the backrest and ...

journal_title：BioMed research international

authors： Yang YS,Chen MD,Fang WC,Chang JJ,Kuo CC

更新日期：2014-01-01 00:00:00

abstract：:Cisplatin is an antitumor drug used in the treatment of a wide variety of malignancies. However, its primary dose-limiting side effect is kidney injury, which is a major clinical concern. To help understand mechanisms involved in the development of kidney injury, cisplatin rodent model has been developed. Given the co...

journal_title：BioMed research international

authors： Perše M,Večerić-Haler Ž

更新日期：2018-09-12 00:00:00

abstract：:Aims. To compare the clinical features of endometrial polyps (EPs) between patients with endometriosis (EM) (EM group) and without EM (non-EM group). Methods and Results. Seventy-six cases in the EM group and 133 cases in the non-EM group underwent laparotomy or hysteroscopy and laparoscopy; later, it was confirmed th...

journal_title：BioMed research international

authors： Wang N,Zhang Y,Liu B

更新日期：2016-01-01 00:00:00

abstract：:Data on genotypic diversity of Mycobacterium tuberculosis complex (MTBC) is important to understand its epidemiology, human adaptation, clinical phenotypes, and drug resistance. This study aimed to characterize MTBC clinical isolates circulating in a predominantly pastoralist area in Ethiopia, a country where tubercul...

journal_title：BioMed research international

authors： Belay M,Ameni G,Bjune G,Couvin D,Rastogi N,Abebe F

更新日期：2014-01-01 00:00:00

abstract：:Helicobacter pylori colonization of gastric mucosa causes pain of unknown etiology in about 15-20% of infected subjects. The aim of the present work was to determine the level of expression of enzymes involved in the synthesis of melatonin in gastric mucosa of asymptomatic and symptomatic H. pylori infected patients. ...

journal_title：BioMed research international

authors： Chojnacki C,Popławski T,Blasiak J,Chojnacki J,Reiter RJ,Klupinska G

更新日期：2013-01-01 00:00:00

abstract：:It has been reported that many modifications occur with the increase of oxidative stress during storage in erythrocytes. In order to delay these negative changes, we evaluated whether the addition of substances likely to protect antioxidant capacity in stored blood would be useful. Therefore, we investigated the effec...

journal_title：BioMed research international

authors： Huyut Z,Şekeroğlu MR,Balahoroğlu R,Karakoyun T,Çokluk E

更新日期：2016-01-01 00:00:00

abstract：:Gravity is crucial for spatial perception, postural equilibrium, and movement generation. The vestibular apparatus is the main sensory system involved in monitoring gravity. Hair cells in the vestibular maculae respond to gravitoinertial forces, but they cannot distinguish between linear accelerations and changes of h...

journal_title：BioMed research international

authors： Lacquaniti F,Bosco G,Gravano S,Indovina I,La Scaleia B,Maffei V,Zago M

更新日期：2014-01-01 00:00:00

abstract：:Red blood cell distribution width (RDW) is a parameter reported in complete blood cell count tests, and has been reported as an inflammatory biomarker. Multiple myeloma (MM) is known to be associated with inflammatory microenvironments. However, the importance of RDW has been seldom studied in MM. For this study, 146 ...

journal_title：BioMed research international

authors： Lee H,Kong SY,Sohn JY,Shim H,Youn HS,Lee S,Kim HJ,Eom HS

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this paper is to examine how well the human induced pluripotent stem cell (hiPSC) colony images can be classified using error-correcting output codes (ECOC). Our image dataset includes hiPSC colony images from three classes (bad, semigood, and good) which makes our classification task a multiclass probl...

journal_title：BioMed research international

authors： Joutsijoki H,Haponen M,Rasku J,Aalto-Setälä K,Juhola M

更新日期：2016-01-01 00:00:00

abstract：:This 12-week clinical study evaluated the impact of 10% CPP-ACP and 5% sodium fluoride varnish regimes on the regression of nonorthodontic white spot lesions (WSLs). The study included 21 children with 101 WSLs who were randomised into four treatment regimes: weekly clinical applications of fluoride varnish for the fi...

journal_title：BioMed research international

authors： Güçlü ZA,Alaçam A,Coleman NJ

更新日期：2016-01-01 00:00:00

abstract：:Recently published evidence has raised concerns about worse late mortality and increasing need for reintervention after off-pump coronary artery bypass grafting. We undertook this study to assess the impact of off-pump coronary artery bypass grafting on survival and freedom from reintervention at 10 years. From Januar...

journal_title：BioMed research international

authors： Raja SG,Husain M,Popescu FL,Chudasama D,Daley S,Amrani M

更新日期：2013-01-01 00:00:00

abstract：:The current morphologically based selection of human embryos for transfer cannot detect chromosome aneuploidies. So far, only biopsy techniques have been able to screen for chromosomal aneuploidies in the in vitro fertilization (IVF) embryos. Preimplantation genetic diagnosis (PGD) or screening (PGS) involves the biop...

journal_title：BioMed research international

authors： Milachich T

更新日期：2014-01-01 00:00:00

abstract：:Triglyceride-glucose index (TyG index) is associated with type 2 diabetes mellitus (T2DM), but research on this relationship is limited in Japan. The purpose of this study was to evaluate the correlation between TyG index and the risk of T2DM in the Japanese population. Here, 12732 participants were selected from the ...

journal_title：BioMed research international

authors： Liu EQ,Weng YP,Zhou AM,Zeng CL

更新日期：2020-12-11 00:00:00

abstract：:Spinocerebellar ataxia-3 (SCA3) is the most common dominant inherited ataxia worldwide and is caused by an unstable CAG trinucleotide expansion mutation within the ATXN3 gene, resulting in an expanded polyglutamine tract within the ATXN3 protein. Many in vitro studies have examined the role of autophagy in neurodegene...

journal_title：BioMed research international

authors： Ou Z,Luo M,Niu X,Chen Y,Xie Y,He W,Song B,Xian Y,Fan D,OuYang S,Sun X

更新日期：2016-01-01 00:00:00

abstract：:Graphene is the first 2-dimensional material and possesses a plethora of original properties. Graphene and its derivatives have exhibited a great potential in a number of fields, both medical and nonmedical. The aim of this review is to set the theoretical basis for further research in developing graphene-based endova...

journal_title：BioMed research international

authors： Patelis N,Moris D,Matheiken S,Klonaris C

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Identification of the factors that influence sedentary behaviour in older adults is important for the design of appropriate intervention strategies. In this study, we determined the prevalence of sedentary behaviour and its association with physical, cognitive, and psychosocial status among older adults resid...

journal_title：BioMed research international

authors： Leung PM,Ejupi A,van Schooten KS,Aziz O,Feldman F,Mackey DC,Ashe MC,Robinovitch SN

更新日期：2017-01-01 00:00:00

abstract：:Apolipoprotein E4 (Apo E4) is the major genetic risk factor in the causation of Alzheimer's disease (AD). In this study we utilize virtual screening of the world's largest traditional Chinese medicine (TCM) database and investigate potential compounds for the inhibition of ApoE4. We present the top three TCM candidate...

journal_title：BioMed research international

authors： Huang HJ,Chen HY,Lee CC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:Introduction. Given its efficacy and safety, NexoBrid™ (NXB) has become part of our therapeutic options in burns treatment with satisfactory results. However, no cost analysis comparing NXB to the standard of care (SOC) has been carried out as of today. Aim. To assess the cost of treatment with NXB and compare it to t...

journal_title：BioMed research international

authors： Giudice G,Filoni A,Maggio G,Bonamonte D,Vestita M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Long-term survival of total knee arthroplasty (TKA) is mainly determined by optimal positioning of the components and prosthesis alignment. Implant positioning can be optimized by computer assisted surgery (CAS). Patient specific cutting blocks (PSCB) seem to have the potential to improve component alignment...

journal_title：BioMed research international

authors： Helmy N,Dao Trong ML,Kühnel SP

更新日期：2014-01-01 00:00:00

abstract：Background and Aims:The NF-κB pathway has been implicated in the genetic aetiology of psoriatic disease. However, since most patients with arthritis have psoriasis, discerning the genetic contributions to both aspects of psoriatic disease is not easy. Our aim was to study the association of common polymorphisms in gene...

journal_title：BioMed research international

authors： Coto-Segura P,Coto E,González-Lara L,Alonso B,Gómez J,Cuesta-Llavona E,Queiro R

更新日期：2019-11-11 00:00:00