Immunotherapy for Bone and Soft Tissue Sarcomas.

abstract：PURPOSE:To evaluate tumor structure in children with diffuse intrinsic pontine glioma (DIPG) using histogram analyses of mean diffusivity (MD), determine potential treatment and corticosteroid-related effects on MD, and monitor changes in MD distributions over time. MATERIALS AND METHODS:DTI was performed on a 1.5T GE...

journal_title：BioMed research international

authors： Steffen-Smith EA,Sarlls JE,Pierpaoli C,Shih JH,Bent RS,Walker L,Warren KE

更新日期：2014-01-01 00:00:00

abstract：:Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory property, the present study performed Gene Ontology and Ingenuity Pathway Analysis (IPA) to describe the basic g...

journal_title：BioMed research international

authors： Li T,Zhu J,Deng F,Wu W,Zheng Z,Lv C,Li Y,Xiang W,Lu X,Qin S

更新日期：2019-03-07 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expre...

journal_title：BioMed research international

authors： Zhang Y,Lin Y,Liu Q,Yuan X,Mao A,Liu Y,Li Q,Zheng J,Hu B,Yu F

更新日期：2018-01-16 00:00:00

abstract：Background:We investigated the potential safety of remimazolam and propofol in malignant hyperthermia- (HM-) susceptible patients using ryanodine receptor 1- (RYR1-) expressing human embryonic kidney- (HEK-) 293 cells. Methods:We compared the enhanced responsiveness of HEK-293 cells expressing wild-type RYR1 with that...

journal_title：BioMed research international

authors： Watanabe T,Miyoshi H,Noda Y,Narasaki S,Morio A,Toyota Y,Kimura H,Mukaida K,Yasuda T,Tsutsumi YM

更新日期：2021-01-04 00:00:00

abstract：:We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μ m amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-inf...

journal_title：BioMed research international

authors： Hiraba H,Inoue M,Gora K,Sato T,Nishimura S,Yamaoka M,Kumakura A,Ono S,Wakasa H,Nakayama E,Abe K,Ueda K

更新日期：2014-01-01 00:00:00

abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

journal_title：BioMed research international

authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

更新日期：2015-01-01 00:00:00

abstract：:Hematopoietic stem cells (HSCs) are unique in their capacity to give rise to all mature cells of the immune system. For years, HSC transplantation has been used for treatment of genetic and neoplastic diseases of the hematopoietic and immune systems. The sourcing of HSCs from human umbilical cord blood has salient adv...

journal_title：BioMed research international

authors： Biancotti JC,Town T

更新日期：2013-01-01 00:00:00

abstract：:Toxoplasma gondii with worldwide distribution has received substantial medical and scientific attentions as it causes serious clinical and veterinary problems especially for pregnant women and immunocompromised patients. Heat shock protein 40 (HSP40) plays a variety of essential roles in the pathogenesis of this proto...

journal_title：BioMed research international

authors： Li ZY,Lu J,Zhou DH,Chen J,Zhu XQ

更新日期：2015-01-01 00:00:00

abstract：:In a bioprospecting effort towards novel thermostable lipases, we assessed the lipolytic profile of 101 bacterial strains isolated from the volcanic area of Santorini, Aegean Sea, Greece. Screening of lipase activity was performed both in agar plates and liquid cultures using olive oil as carbon source. Significant di...

journal_title：BioMed research international

authors： Stathopoulou PM,Savvides AL,Karagouni AD,Hatzinikolaou DG

更新日期：2013-01-01 00:00:00

abstract：:Protein structure prediction (PSP) is computationally a very challenging problem. The challenge largely comes from the fact that the energy function that needs to be minimised in order to obtain the native structure of a given protein is not clearly known. A high resolution 20 × 20 energy model could better capture th...

journal_title：BioMed research international

authors： Rashid MA,Newton MA,Hoque MT,Sattar A

更新日期：2013-01-01 00:00:00

abstract：:In this study, we prepared PTX-loaded mesoporous hollow SnO2 nanofibers conjugated with folic acid (SFNFP) for liver cancer therapy. According to SEM and TEM characterization, SFNF showed a mesoporous hollow structure. The average outer diameter was 200 nm, and the wall thickness was 50 nm. The DSC and XRD study showe...

journal_title：BioMed research international

authors： Lv H,Wu C,Liu X,Bai A,Cao Y,Shang W,Hu L,Liu Y

更新日期：2018-11-25 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/4671349.]. ...

journal_title：BioMed research international

authors： Dhahri H,Rahmany I,Mahmood A,Al Maghayreh E,Elkilani W

更新日期：2020-06-30 00:00:00

abstract：OBJECTIVE:To assess quality of care of women with severe maternal morbidity and to identify associated factors. METHOD:This is a national multicenter cross-sectional study performing surveillance for severe maternal morbidity, using the World Health Organization criteria. The expected number of maternal deaths was cal...

journal_title：BioMed research international

authors： Haddad SM,Cecatti JG,Souza JP,Sousa MH,Parpinelli MA,Costa ML,Pacagnella RC,Brum IR,Moraes Filho OB,Feitosa FE,Menezes CA,Guanabara EM,Moreira JL,Peret FA,Schmaltz LE,Katz L,Lima AC,Amorim MM,Martins MG,Nascimento D

更新日期：2014-01-01 00:00:00

abstract：:Background. Endemic areas of tegumentary leishmaniasis (TL) in Salta, Argentina, present some overlap zones with the geographical distribution of Chagas disease, with mixed infection cases being often detected. Objectives. The purpose of this study was to determine the magnitude of Leishmania sp. infection and potenti...

journal_title：BioMed research international

authors： Hoyos CL,Cajal SP,Juarez M,Marco JD,Alberti D'Amato AM,Cayo M,Torrejón I,Cimino RO,Diosque P,Krolewiecki AJ,Nasser JR,Gil JF

更新日期：2016-01-01 00:00:00

abstract：:Inorganic arsenic (iAs) exposure induces a decrease in glucose type 4 transporter (GLUT4) expression on the adipocyte membrane, which may be related to premature births and low birth weight infants in women exposed to iAs at reproductive age. The aim of this study was to analyze the effect of sodium arsenite (NaAsO2) ...

journal_title：BioMed research international

authors： Gutiérrez-Torres DS,González-Horta C,Del Razo LM,Infante-Ramírez R,Ramos-Martínez E,Levario-Carrillo M,Sánchez-Ramírez B

更新日期：2015-01-01 00:00:00

abstract：:It has been described renal damage in rats with vascular calcification. The organic anion transporter 5 (Oat5) is only expressed in kidney, and its urinary excretion was proposed as potential early biomarker of renal injury. The aim of this study was to evaluate the Oat5 renal expression and its urinary excretion in a...

journal_title：BioMed research international

authors： Hazelhoff MH,Bulacio RP,Torres AM

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To identify the Acinetobacter baumannii infection among transfusion dependent thalassemia patients. METHODS:A quantitative approach was employed to assess Acinetobacter baumannii infection in transfusion dependent thalassemia patients. Samples were collected from 916 patients, which have shown bacterial growth...

journal_title：BioMed research international

authors： Abdul Rasheed M,Alzahrani FM,Sattar Shaikh S

更新日期：2017-01-01 00:00:00

abstract：:Muscle mass and strength progressively decrease with age, which results in a condition known as sarcopenia. Sarcopenia would lead to physical disability, poor quality of life, and death. Therefore, much is expected of an effective intervention for sarcopenia. Epidemiologic, clinical, and laboratory evidence suggest an...

journal_title：BioMed research international

authors： Wagatsuma A,Sakuma K

更新日期：2014-01-01 00:00:00

abstract：:The purpose of the present study was to examine the convergent and divergent validity of the Biber Cognitive Estimation Test (BCET) in individuals with ABI undergoing postacute rehabilitation and to assess the measure's ability to account for unique variance in community integration following rehabilitation. Participa...

journal_title：BioMed research international

authors： Fortune DG,Richards HL

更新日期：2017-01-01 00:00:00

abstract：:The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feeds, but its effects on fish have not yet been investigated extensively. In order to fill this gap a feeding trial with juvenile carp was conducted. Three groups of fish were fed feeds contaminated with ZEN at three concentrations (low: 332 μg kg(-1...

journal_title：BioMed research international

authors： Pietsch C,Junge R,Burkhardt-Holm P

更新日期：2015-01-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) has several functions in the central nervous system, where it contributes to brain development and its functionality through affecting neuronal survival and activity and also modulating neurotransmitter levels. This neurotrophin is also found in the serum, but its origin and pe...

journal_title：BioMed research international

authors： Türck P,Frizzo ME

更新日期：2015-01-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSC) hold tremendous potential for personalized cell-based therapy for skin regeneration. Aiming to establish human iPSCs as a potential cell source for skin tissue engineering, we expect to obtain an epidermal-like cell line with angiogenic and keratinogenic differentiation potential ...

journal_title：BioMed research international

authors： Lin W,Chen M,Hu C,Qin S,Chu C,Xiang L,Man Y,Qu Y

更新日期：2018-09-13 00:00:00

abstract：Introduction:To investigate the clinical results of arthroscopic management for the unstable inferior leaf of the lateral meniscus anterior horn and associated cysts through an inframeniscal portal. Methods:From March 2005 to October 2014, 64 patients with an unstable inferior leaf of the lateral meniscus anterior hor...

journal_title：BioMed research international

authors： Chen D,Li Q,Sun Y,Qin J,Yao Y,Jiang Q

更新日期：2017-01-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn disease (CD). Similar symptoms, but different treatment procedures for both diseases require precise diagnosis. MicroRNAs (miRNAs) are major posttranscriptional players that regulate the expression of genes during the inflammation and thus co...

journal_title：BioMed research international

authors： Guz M,Dworzański T,Jeleniewicz W,Cybulski M,Kozicka J,Stepulak A,Celiński K

更新日期：2020-07-22 00:00:00

abstract：:Preeclampsia (PE) is a unique complication of pregnancy, the pathogenesis of which has been generally accepted to be associated with the dysfunctions of extravillous trophoblast (EVT) including proliferation, apoptosis, and migration and invasion. Decorin (DCN) has been proved to be a decidua-derived TGF-binding prote...

journal_title：BioMed research international

authors： Zou Y,Yu X,Lu J,Jiang Z,Zuo Q,Fan M,Huang S,Sun L

更新日期：2015-01-01 00:00:00

abstract：:Mesenchymal stromal cells (MSCs) are multipotent cells, which can give rise to several cell types including osteoblasts, adipocytes, and chondroblasts. These cells can be found in a variety of adult and fetal tissues, such as bone marrow, adipose tissue, cord blood, and placenta. In recent years, the biological proper...

journal_title：BioMed research international

authors： Haddad R,Saldanha-Araujo F

更新日期：2014-01-01 00:00:00

abstract：:The aim of the present study was to determine the anti-inflammatory effect of IFN-τ on endometritis using a mouse model of S. aureus-induced endometritis and to elucidate the mechanism of action underlying these effects. In the present study, the effect of IFN-τ on S. aureus growth was monitored by turbidimeter at 600...

journal_title：BioMed research international

authors： Zhang Z,Guo Y,Liu Y,Li C,Guo M,Deng G

更新日期：2017-01-01 00:00:00

abstract：:The research was performed on male Wistar rats based on assumptions that new microelement preparations containing metal nanoparticles and their agglomerates had potential. Morphological and functional changes in tissues in the injection site and dynamics of chemical element metabolism (25 indicators) in body were asse...

journal_title：BioMed research international

authors： Sizova E,Miroshnikov S,Yausheva E,Polyakova V

更新日期：2015-01-01 00:00:00

abstract：:Acute nonspecific, or primary, mesenteric lymphadenitis is a self-limiting inflammatory condition affecting the mesenteric lymph nodes, whose presentation mimics appendicitis or intussusception. It typically occurs in children, adolescents, and young adults. White blood count and C-reactive protein are of limited usef...

journal_title：BioMed research international

authors： Helbling R,Conficconi E,Wyttenbach M,Benetti C,Simonetti GD,Bianchetti MG,Hamitaga F,Lava SA,Fossali EF,Milani GP

更新日期：2017-01-01 00:00:00

abstract：:Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and exist as an important cause of pulmonary infections in humans. Pulmonary involvement is the most common disease manifestation of NTM and the incidence of NTM is growing in North America. Susceptibility to NTM infection is incompletely understood; ...

journal_title：BioMed research international

authors： Mirsaeidi M,Farshidpour M,Allen MB,Ebrahimi G,Falkinham JO

更新日期：2014-01-01 00:00:00