Endowing iPSC-Derived MSCs with Angiogenic and Keratinogenic Differentiation Potential: A Promising Cell Source for Skin Tissue Engineering.

abstract：Objective:The objective of this study is to evaluate the effect of simvastatin on the jaw bone microstructural defect and autophagy in rats with high cholesterol diet (HCD). Methods:Male Sprague-Dawley rats were fed a standard rodent chow (NC group) or a high cholesterol diet for 32 weeks and the HCD-fed rats were tre...

journal_title：BioMed research international

authors： Zhou J,Gao X,Huang S,Ma L,Cui Y,Wang H,Qiu J,Wang L,Dong Q,Chen Z,Wang X,Zhang D

更新日期：2018-06-27 00:00:00

abstract：:Increasing studies have revealed that long noncoding RNAs (lncRNAs) are not transcriptional noise but play important roles in the regulation of a wide range of biological processes, and the dysregulation of lncRNA genes is associated with disease development. Alzheimer's disease (AD) is a chronic neurodegenerative dis...

journal_title：BioMed research international

authors： Wan G,Zhou W,Hu Y,Ma R,Jin S,Liu G,Jiang Q

更新日期：2016-01-01 00:00:00

abstract：:With the development of molecular ecology, increasing low-abundance microbial populations were detected in oil reservoirs. However, our knowledge about the oil recovery potential of these populations is lacking. In this study, the oil recovery potential of low-abundance Dietzia that accounts for less than 0.5% in micr...

journal_title：BioMed research international

authors： Gao P,Wang H,Li G,Ma T

更新日期：2019-10-02 00:00:00

abstract：:Tomatoes and tomato based-foods contain beneficial microorganisms and various organic acids that have important nutritional values for human. The objective of this study was to access the physiochemical properties of fermented tomatoes juices and to evaluate the competitiveness of lactic acid bacteria (LAB) against Li...

journal_title：BioMed research international

authors： Bah A,Albano H,Barbosa JB,Fhoula I,Gharbi Y,Najjari A,Boudabous A,Teixeira P,Ouzari HI

更新日期：2019-02-26 00:00:00

abstract：:In clinical endodontics, preoperative estimation of root canal curvature is crucial regarding the prevention of iatrogenic errors. Reproduction of the two-dimensional radiographic images causes certain proximal view curvatures not seen. Therefore, the present study is aimed at investigating the degree of root canal cu...

journal_title：BioMed research international

authors： Faraj BM

更新日期：2021-01-13 00:00:00

abstract：:Bacteria are a source of a large number of secondary metabolites with several biomedical and biotechnological applications. In recent years, there has been tremendous progress in the development of novel synthetic biology approaches both to increase the production rate of secondary metabolites of interest in native pr...

journal_title：BioMed research international

authors： de Frias UA,Pereira GKB,Guazzaroni ME,Silva-Rocha R

更新日期：2018-07-09 00:00:00

abstract：:The aim of this study was to evaluate the apical microleakage of Biodentine and MTA orthograde apical plugs and to compare the effect of thickness of these biomaterials on their sealing ability. A total of eighty maxillary anterior teeth were used. The apices were removed by cutting with a diamond disc (Jota, Germany)...

journal_title：BioMed research international

authors： Bani M,Sungurtekin-Ekçi E,Odabaş ME

更新日期：2015-01-01 00:00:00

abstract：:Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...

journal_title：BioMed research international

authors： Tan BL,Norhaizan ME

更新日期：2017-01-01 00:00:00

abstract：:Astragalus membranaceus polysaccharide (APS) components are main ingredients of TCM and have proven efficacy to activate T cells and B cells, enhancing immunity in humans. In this study, elevated cytokine and anti-PD-1 antibody titers were found in mice after immunization with APS. Therefore, phage-display technology ...

journal_title：BioMed research international

authors： Chang FL,Tsai KC,Lin TY,Yang TW,Lo YN,Chen WC,Chang JH,Lu MK,Chiou CT,Chen PH,Yen Y,Pan SL,Lee YC

更新日期：2020-03-03 00:00:00

abstract：:The receptor activator of NF-κB (RANK) pathway is involved in bone health as well as breast cancer (BC) pathogenesis and progression. Whereas the therapeutic implication of this pathway is established for the treatment of osteoporosis and bone metastases, the application in adjuvant BC is currently investigated. As ge...

journal_title：BioMed research international

authors： Hein A,Bayer CM,Schrauder MG,Häberle L,Heusinger K,Strick R,Ruebner M,Lux MP,Renner SP,Schulz-Wendtland R,Ekici AB,Hartmann A,Beckmann MW,Fasching PA

更新日期：2014-01-01 00:00:00

abstract：:Molecular recognition elements (MREs) can be short sequences of single-stranded DNA, RNA, small peptides, or antibody fragments. They can bind to user-defined targets with high affinity and specificity. There has been an increasing interest in the identification and application of nucleic acid molecular recognition el...

journal_title：BioMed research international

authors： Hong KL,Sooter LJ

更新日期：2015-01-01 00:00:00

abstract：:The 13 million nurses worldwide constitute most of the global healthcare workforce and are uniquely positioned to engage with others to address disparities in healthcare to achieve the goal of better health for all. A new vision for nurses involves active participation and collaboration with international colleagues a...

journal_title：BioMed research international

authors： Premji SS,Hatfield J

更新日期：2016-01-01 00:00:00

abstract：:The purpose of this study is to evaluate the therapeutic effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSC) activated by curcumin (CUR) on PC12 cells induced by 1-methyl-4-phenylpyridinium ion (MPP+), a cell model of Parkinson's disease (PD). The supernatant of hUC-MSC and hUC-MSC activated by 5 ...

journal_title：BioMed research international

authors： Jinfeng L,Yunliang W,Xinshan L,Yutong W,Shanshan W,Peng X,Xiaopeng Y,Zhixiu X,Qingshan L,Honglei Y,Xia C,Hongwei W,Bingzhen C

更新日期：2016-01-01 00:00:00

abstract：AIM:Gastrointestinal mucositis is a frequent complication of antineoplastic chemotherapy, but the effects of chemotherapy on mucosal defense mechanisms remain poorly understood. We studied the effects of cisplatin on mucin, one of the principal defense factors of the gastrointestinal mucosa, and evaluated the efficacy ...

journal_title：BioMed research international

authors： Yamamoto H,Ishihara K,Takeda Y,Koizumi W,Ichikawa T

更新日期：2013-01-01 00:00:00

abstract：:The influence of biomimetic calcium phosphate coating on osteoblasts behavior in vitro is not well established yet. In this study, we investigated the behavior of osteoblastic rat osteosarcoma 17/2.8 cells (ROS17/2.8) on two groups of biomaterial surfaces: alkaline-treated titanium surface (ATT) and biomimetic calcium...

journal_title：BioMed research international

authors： Yu X,Wei M

更新日期：2013-01-01 00:00:00

abstract：:Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanism...

journal_title：BioMed research international

authors： Gonzalez CD,Alvarez S,Ropolo A,Rosenzvit C,Bagnes MF,Vaccaro MI

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The prognosis of patients with advanced oropharyngeal carcinoma (OPSCC) is generally poor. The aim of this study is to investigate the different therapeutic approaches and identify prognostic factors associated with a worse outcome for patients treated for T4a OPSCC, in order to improve treatment selection f...

journal_title：BioMed research international

authors： Psychogios G,Mantsopoulos K,Agaimy A,Brunner K,Mangold E,Zenk J,Iro H

更新日期：2014-01-01 00:00:00

abstract：:This study was conducted to determine the effects of feeding oil palm frond silage based diets with added linseed oil (LO) containing high α -linolenic acid (C18:3n-3), namely, high LO (HLO), low LO (LLO), and without LO as the control group (CON) on the fatty acid (FA) composition of subcutaneous adipose tissue and t...

journal_title：BioMed research international

authors： Ebrahimi M,Rajion MA,Goh YM,Sazili AQ,Schonewille JT

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to describe the clinical and demographic characteristics of UC in Bahia, a Brazilian state, and to identify the variables associated with extensive colitis, steroid therapy, immunosuppression, and colectomy. METHODS:In this cross-sectional study UC patients were interviewed, ...

journal_title：BioMed research international

authors： da Silva BC,Lyra AC,Mendes CM,Ribeiro CP,Lisboa SR,de Souza MT,Portela RC,Santana GO

更新日期：2015-01-01 00:00:00

abstract：:TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dynamics simulations ...

journal_title：BioMed research international

authors： Wan H,Chang S,Hu JP,Tian XH,Wang MH

更新日期：2016-01-01 00:00:00

abstract：:Densitometry data generated for Western blots are commonly used to compare protein abundance between samples. In the last decade, it has become apparent that assumptions underpinning these comparisons are often violated in studies reporting Western blot data in the literature. These violations can lead to erroneous in...

journal_title：BioMed research international

authors： Butler TAJ,Paul JW,Chan EC,Smith R,Tolosa JM

更新日期：2019-01-21 00:00:00

abstract：:Graphene is the first 2-dimensional material and possesses a plethora of original properties. Graphene and its derivatives have exhibited a great potential in a number of fields, both medical and nonmedical. The aim of this review is to set the theoretical basis for further research in developing graphene-based endova...

journal_title：BioMed research international

authors： Patelis N,Moris D,Matheiken S,Klonaris C

更新日期：2016-01-01 00:00:00

abstract：Background:Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS varies in different subtypes of acute ischemic stroke (AIS) and that BRS is a predictor of clinical outcomes. Methods:We examined autonomic parameters in 34 patients with AI...

journal_title：BioMed research international

authors： Tsai WC,Lin HC,Lai YR,Hsu CW,Huang CC,Wang HC,Su CM,Su YJ,Lin WC,Cheng BC,Chang WN,Lu CH,Tsai NW

更新日期：2019-04-18 00:00:00

abstract：:Medicinal plants have played an important role in the treatment of many diseases. Medicinal plants are believed to be well appropriate with the human body and to produce less side influences than the pharmaceuticals. Kingdom of Saudi Arabia has abundant and wide variety of medicinal plants whose therapeutic effects ha...

journal_title：BioMed research international

authors： Almalki DA,Alghamdi SA,Al-Attar AM

更新日期：2019-02-27 00:00:00

abstract：:Ovarian cancer (OvCa) is an intractable gynecological malignancy due to the high recurrence rate. Several molecular biomarkers have been previously screened for early identifying patients with a high recurrence risk and poor prognosis. However, all the known studies focused on a single type of RNAs, not integrating va...

journal_title：BioMed research international

authors： Zhang Y,Ye Q,He J,Chen P,Wan J,Li J,Yang Y,Li X

更新日期：2020-02-14 00:00:00

abstract：:In order to understand disease pathogenesis, improve medical diagnosis, or discover effective drug targets, it is important to identify significant genes deeply involved in human disease. For this purpose, many earlier approaches attempted to prioritize candidate genes using gene expression profiles or SNP genotype da...

journal_title：BioMed research international

authors： Che J,Shin M

更新日期：2015-01-01 00:00:00

abstract：:Background. Genome-wide association studies (GWAS) have shown its revolutionary power in seeking the influenced loci on complex diseases genetically. Thousands of replicated loci for common traits are helpful in diseases risk assessment. However it is still difficult to elucidate the variations in these loci that dire...

journal_title：BioMed research international

authors： Ma LX,Wang YJ,Wang JF,Li X,Hao P

更新日期：2013-01-01 00:00:00

abstract：:This work evaluated the physicochemical properties and antioxidant activity of spray dried extracts (SDE) from Psidium guajava L. leaves. Different drying carriers, namely, maltodextrin, colloidal silicon dioxide, Arabic gum, and β -cyclodextrin at concentrations of 40 and 80% relative to solids content, were added to...

journal_title：BioMed research international

authors： Fernandes MR,Azzolini AE,Martinez ML,Souza CR,Lucisano-Valim YM,Oliveira WP

更新日期：2014-01-01 00:00:00

abstract：:Many topical agents are available for treating the acute phase of acne; however, few agents have been proven beneficial during the maintenance phase. Objective. To evaluate the efficacy and safety of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid during the maintenance phase of ...

journal_title：BioMed research international

authors： Kulthanan K,Trakanwittayarak S,Tuchinda P,Chularojanamontri L,Limphoka P,Varothai S

更新日期：2020-10-16 00:00:00

abstract：BACKGROUND:This retrospective study was designed to investigate the efficacy and safety of intermittent portal triad clamping (PTC) with low central venous pressure (CVP) in liver resections. METHODS:Between January 2007 and August 2013, 115 patients underwent liver resection with intermittent PTC. The patients' data ...

journal_title：BioMed research international

authors： Topaloglu S,Yesilcicek Calik K,Calik A,Aydın C,Kocyigit S,Yaman H,Kutanis D,Karabulut E,Dohman D,Orem A,Arslan MK

更新日期：2013-01-01 00:00:00