Scientific Evidence of Rice By-Products for Cancer Prevention: Chemopreventive Properties of Waste Products from Rice Milling on Carcinogenesis In Vitro and In Vivo.

abstract：:Oral mucosa is an attractive region for the local and systemic application of many drugs. Oral mucoadhesive films are preferred for their prolonged time of residence, the improved bioavailability of the drug they contain, their painless application, their protection against lesions, and their nonirritating properties....

journal_title：BioMed research international

authors： Landová H,Vetchý D,Gajdziok J,Doležel P,Muselík J,Dvořáčková K,Jekl V,Hauptman K,Knotek Z

更新日期：2014-01-01 00:00:00

abstract：:The new chemokine Prokineticin 2 (PROK2) and its receptors (PKR1 and PKR2) have a role in inflammatory pain and immunomodulation. Here we identified PROK2 as a critical mediator of neuropathic pain in the chronic constriction injury (CCI) of the sciatic nerve in mice and demonstrated that blocking the prokineticin rec...

journal_title：BioMed research international

authors： Lattanzi R,Maftei D,Marconi V,Florenzano F,Franchi S,Borsani E,Rodella LF,Balboni G,Salvadori S,Sacerdote P,Negri L

更新日期：2015-01-01 00:00:00

abstract：:Background. The survival rates of in-hospital cardiac arrests (IHCAs) are reportedly low at night, but the difference between the survival rates of cardiac origin and noncardiac origin IHCAs occurring at night remains unclear. Methods. Outcomes of IHCAs during different shifts (night, day, and evening) were compared a...

journal_title：BioMed research international

authors： Syue YJ,Huang JB,Cheng FJ,Kung CT,Li CJ

更新日期：2016-01-01 00:00:00

abstract：:This prospective randomized study is to evaluate the locoregional failure and its impact on survival by comparing involved field radiotherapy (IFRT) with elective nodal irradiation (ENI) in combination with concurrent chemotherapy for locally advanced non-small cell lung cancer. It appears that higher dose could be de...

journal_title：BioMed research international

authors： Chen M,Bao Y,Ma HL,Hu X,Wang J,Wang Y,Peng F,Zhou QC,Xie CH

更新日期：2013-01-01 00:00:00

abstract：:The main aim was to analyse the associations between several physical fitness variables and bone parameters in a sample of elderly people. 129 participants (94 females and 35 males, 76.2 ± 5.4 y) from the EXERNET cohort of Zaragoza (Spain) were included in the study. Physical fitness was assessed using the Senior Fitn...

journal_title：BioMed research international

authors： Moradell A,Gómez-Cabello A,Gómez-Bruton A,Muniz-Pardos B,Puyalto JM,Matute-Llorente A,Gónzalez-Agüero A,Ara I,Casajús JA,Vicente-Rodríguez G

更新日期：2020-07-15 00:00:00

abstract：:Freshly ejaculated spermatozoa are incapable or poorly capable of fertilizing an oocyte. The fertilization aptness of spermatozoa depends on the appropriate and time-dependent acquisition of hyperactivation, chemotaxis, capacitation, and the acrosome reaction, where calcium (Ca(2+)) is extensively involved in almost e...

journal_title：BioMed research international

authors： Rahman MS,Kwon WS,Pang MG

更新日期：2014-01-01 00:00:00

abstract：Background:The Biodex Biosway® Balance System and SWAY Balance® Mobile smartphone application (SBMA) are portable instruments that assess balance function with force plate and accelerometer technology, respectively. The validity of these indirect clinical measures of postural sway merits investigation. Purpose:The pur...

journal_title：BioMed research international

authors： Dewan BM,Roger James C,Kumar NA,Sawyer SF

更新日期：2019-12-21 00:00:00

abstract：:A number of statistical methods for detecting gene-gene interactions have been developed in genetic association studies with binary traits. However, many phenotype measures are intrinsically quantitative and categorizing continuous traits may not always be straightforward and meaningful. Association of gene-gene inter...

journal_title：BioMed research international

authors： Yee J,Kwon MS,Jin S,Park T,Park M

更新日期：2015-01-01 00:00:00

abstract：:Epigenetic changes have major role in the normal development and programming of gene expression. Aberrant methylation results in carcinogenesis. The primary objective of our study is to determine whether primary tumor tissue and cultured tumor cells in 2D and 3D tissue culture systems have the same methylation signatu...

journal_title：BioMed research international

authors： Şükrüoğlu Erdoğan Ö,Kılıç Erciyas S,Bilir A,Buğra Tunçer Ş,Akdeniz Ödemiş D,Kurul S,Karanlık H,Cabıoğlu N,Yazıcı H

更新日期：2019-01-17 00:00:00

abstract：:Introduction. Luteolin, a falconoid compound in many Chinese herbs and formula, plays important roles in cardiovascular diseases. The underlying mechanism of luteolin remains to be further elaborated. Methods. A model of hydrogen peroxide- (H2O2-) induced H9C2 cells apoptosis was established. Cell viabilities were exa...

journal_title：BioMed research international

authors： Chang H,Li C,Huo K,Wang Q,Lu L,Zhang Q,Wang Y,Wang W

更新日期：2016-01-01 00:00:00

abstract：:We have developed a new "drug" and approach that appear to be effective in reducing arterial age. This "drug" represents a low, subtherapeutic dose of statin and sartan and particularly their low-dose combination. The improvement of arterial wall characteristics, also reflecting in a decrease of arterial age, was achi...

journal_title：BioMed research international

authors： Janić M,Lunder M,Šabovič M

更新日期：2015-01-01 00:00:00

abstract：:One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signaling processes. ER stressors can induce autophagy-dependent survival;...

journal_title：BioMed research international

authors： Holczer M,Márton M,Kurucz A,Bánhegyi G,Kapuy O

更新日期：2015-01-01 00:00:00

abstract：Objective:To analyze the ten-year surgical outcomes and postoperative complications of French-Door laminoplasty (FDL) in the management of multilevel cervical spondylotic myelopathy (MCSM) and analyze the prognostic factors for FDL in treating MCSM. Methods:64 patients with MCSM, who were operated by FDL, were include...

journal_title：BioMed research international

authors： Chen G,Liu X,Chen N,Chen B,Zou X,Wei F,Liu S

更新日期：2020-05-06 00:00:00

abstract：:Photosystem II photochemistry and phycobiliprotein (PBP) genes of red algae Kappaphycus alvarezii, raw material of κ -carrageenan used in food and pharmaceutical industries, were analyzed in this study. Minimum saturating irradiance (I k) of this algal species was less than 115 μmol m(-2) s(-1). Its actual PSII effici...

journal_title：BioMed research international

authors： Guan X,Wang J,Zhu J,Yao C,Liu J,Qin S,Jiang P

更新日期：2013-01-01 00:00:00

abstract：:This study included 30 patients with diagnosed rheumatoid arthritis (RA) and 30 test subjects without RA (control group). The objective of the study was to examine both groups for the presence of temporomandibular disorders (TMD) and morphological changes of the temporomandibular joint (TMJ). All individuals were exam...

journal_title：BioMed research international

authors： Witulski S,Vogl TJ,Rehart S,Ottl P

更新日期：2014-01-01 00:00:00

abstract：Background:sCD30 and sCD26 are correlated with autoimmune diseases. However, little research has been done on the relationship between them and primary immune thrombocytopenia (ITP). Methods:This study enrolled 47 patients diagnosed with ITP in the Institute of Hematology and Blood Disease Hospital, Chinese Academy of...

journal_title：BioMed research international

authors： Wang H,Gu X,Li H,Yin L,Tao W,Yu J,Zhou Q,Mu H,Shen Y,Yao J,Liu L,Bi H,Yang R,Zhou Z

更新日期：2020-03-31 00:00:00

abstract：:RRM2B gene encodes ribonucleoside-diphosphate reductase subunit M2 B, the p53-inducible small subunit (p53R2) of ribonucleotide reductase (RNR), an enzyme catalyzing dNTP synthesis for mitochondrial DNA. Defects in this gene may cause severe mitochondrial disease affecting mainly the nervous system. This study is aime...

journal_title：BioMed research international

authors： Ait El Cadi C,Krami AM,Charoute H,Elkarhat Z,Sifeddine N,Lakhiari H,Rouba H,Barakat A,Nahili H

更新日期：2020-07-25 00:00:00

abstract：Purpose:Coconut water has long been touted for its medicinal qualities including natural hydration. We sought to determine whether its consumption would induce changes to urinary lithogenic factors beyond changes in urine volume. Materials and Methods:After Institutional Review Board approval, volunteers with no prior...

journal_title：BioMed research international

authors： Patel RM,Jiang P,Asplin J,Granja I,Capretz T,Osann K,Okhunov Z,Landman J,Clayman RV

更新日期：2018-11-01 00:00:00

abstract：:Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...

journal_title：BioMed research international

authors： Léonard B,Kridelka F,Delbecque K,Goffin F,Demoulin S,Doyen J,Delvenne P

更新日期：2014-01-01 00:00:00

abstract：Purpose:Computer-aided diagnosis (CAD) can aid in improving diagnostic level; however, the main problem currently faced by CAD is that it cannot obtain sufficient labeled samples. To solve this problem, in this study, we adopt a generative adversarial network (GAN) approach and design a semisupervised learning algorith...

journal_title：BioMed research international

authors： Zheng G,Han G,Soomro NQ,Ma L,Zhang F,Zhao Y,Zhao X,Zhou C

更新日期：2019-04-15 00:00:00

abstract：:This study aimed to compare within-subject blood pressure (BP) variabilities from different measurement techniques. Cuff pressures from three repeated BP measurements were obtained from 30 normotensive and 30 hypertensive subjects. Automatic BPs were determined from the pulses with normalised peak amplitude larger tha...

journal_title：BioMed research international

authors： Yang F,Chen F,Zhu M,Chen A,Zheng D

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:There is an unmet need for a specific cardiovascular risk (CV) algorithm for rheumatoid arthritis (RA) patients. Lipoprotein data are often not available in RA cohorts but could be obtained from frozen blood samples. The objective of this study was to estimate the storage effect on lipoproteins in long-term (...

journal_title：BioMed research international

authors： Arts EE,Popa CD,Smith JP,Arntz OJ,van de Loo FA,Donders R,Semb AG,Kitas GD,van Riel PL,Fransen J

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:In the process of care for disorders of sex development (DSD), clinical decisions should focus on the long-term quality of life (QOL). We sought to investigate the QOL of patients with DSD in China. DESIGN:Case-control study was carried out. PATIENTS:90 patients of DSD participated in the study. Finally, 87...

journal_title：BioMed research international

authors： Wang C,Tian Q

更新日期：2015-01-01 00:00:00

abstract：:Our previous studies have demonstrated that diabetes-induced oxidative stress alters homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor, proNGF, at the expense of NGF which plays a critical role in preserving neuronal and retinal function. This imbalance coincided with retinal ...

journal_title：BioMed research international

authors： Mysona BA,Matragoon S,Stephens M,Mohamed IN,Farooq A,Bartasis ML,Fouda AY,Shanab AY,Espinosa-Heidmann DG,El-Remessy AB

更新日期：2015-01-01 00:00:00

abstract：:Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful fo...

journal_title：BioMed research international

authors： Henriquez-Camacho C,Losa J

更新日期：2014-01-01 00:00:00

abstract：:Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a pressure overload-induced early and late stage heart fai...

journal_title：BioMed research international

authors： Wang X,Song C,Zhou X,Han X,Li J,Wang Z,Shang H,Liu Y,Cao H

更新日期：2017-01-01 00:00:00

abstract：:Exposure to dioxins, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is reported to affect the autoimmune system and increase the risk of autoimmune disease. Generally, dioxin exerts its toxicity via aryl hydrocarbon receptor (AhR). Primary biliary cholangitis (PBC) is a chronic autoimmune disease, and its pathoge...

journal_title：BioMed research international

authors： She C,Wang J,Tang N,Liu Z,Xu L,Liu B

更新日期：2020-08-24 00:00:00

abstract：:The cytosolic isozyme of phosphoenolpyruvate carboxykinase (PCK1) was the first rate-limiting enzyme in the gluconeogenesis pathway, which exerted a critical role in maintaining the blood glucose levels. PCK1 has been established to be involved in various physiological and pathological processes, including glucose met...

journal_title：BioMed research international

authors： Yuan Y,Lin JY,Cui HJ,Zhao W,Zheng HL,Jiang ZW,Xiong XD,Xu S,Liu XG

更新日期：2020-02-12 00:00:00

abstract：:No pharmacological treatment is currently available to protect brain from neuronal damage after ischemic stroke. Recent studies found that enkephalin may play an important role in neuron regeneration. We assembled a homogeneous size vesicle constituted by transferrin, exosomes, and enkephalin. Immunofluorescence assay...

journal_title：BioMed research international

authors： Liu Y,Fu N,Su J,Wang X,Li X

更新日期：2019-03-04 00:00:00

abstract：:Arrhythmia is a disease that is caused by abnormal electrical activity in the heart rate or rhythm. It is the major cause of cardiovascular morbidity and mortality. Although several antiarrhythmic drugs have been used in clinic for decades, their application is often limited by their adverse effects. As a result, natu...

journal_title：BioMed research international

authors： Li J,Hu D,Song X,Han T,Gao Y,Xing Y

更新日期：2017-01-01 00:00:00