A clinical and pathological overview of vulvar condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma.

abstract：:The normal physiological loads from muscles experienced by the spine are largely unknown due to a lack of data. The aim of this study is to investigate the effects of varying muscle directions on the outcomes predicted from finite element models of human lumbar spine. A nonlinear finite element model of L3-L5 was empl...

journal_title：BioMed research international

authors： Zhu R,Niu WX,Wang ZP,Pei XL,He B,Zeng ZL,Cheng LM

更新日期：2018-01-03 00:00:00

abstract：:We aimed to assess the prevalence of hospitalization for endometriosis in the general population in France and in each French region and to describe temporal trends, rehospitalization rates, and prevalence of the different types of endometriosis. The analyses were carried out on French hospital discharge data and cove...

journal_title：BioMed research international

authors： von Theobald P,Cottenet J,Iacobelli S,Quantin C

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Recovery of walking outdoors after hip fracture is important for equal participation in the community. The causes of poor recovery are not fully understood. This study investigates recovery of walking outdoors and associated determinants after hip fracture. METHODS:A prospective follow-up study, among clinical...

journal_title：BioMed research international

authors： Salpakoski A,Törmäkangas T,Edgren J,Sihvonen S,Pekkonen M,Heinonen A,Pesola M,Kallinen M,Rantanen T,Sipilä S

更新日期：2014-01-01 00:00:00

abstract：Background:Long noncoding RNAs (lncRNAs) play a crucial role in varieties of biological processes. This study is aimed at investigating meniscal degeneration-specific lncRNAs and mRNAs and their related networks in knee osteoarthritis (KOA). Methods:The dataset GSE98918, which included 24 meniscus samples and related ...

journal_title：BioMed research international

authors： Zhao J,Su Y,Jiao J,Wang Z,Fang X,He X,Zhang X,Liu Z,Xu X

更新日期：2020-05-20 00:00:00

abstract：:GHK (glycyl-L-histidyl-L-lysine) is present in human plasma, saliva, and urine but declines with age. It is proposed that GHK functions as a complex with copper 2+ which accelerates wound healing and skin repair. GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity ...

journal_title：BioMed research international

authors： Pickart L,Vasquez-Soltero JM,Margolina A

更新日期：2015-01-01 00:00:00

abstract：:Maintaining regular blood pressure control usually requires multidrug regimens rather than monotherapy. The objective of this study was to describe the effectiveness and safety of an angiotensin-converting enzyme inhibitor and a nondihydropyridine calcium channel blocker in a single-tablet combination in patients with...

journal_title：BioMed research international

authors： Atalar E,Eskin F,Tugtekin HB,Karabulut A,Kanyilmaz S,Kirbiyik H,Ozyildiz AG

更新日期：2020-09-05 00:00:00

abstract：:Hypolactasia, or intestinal lactase deficiency, affects more than half of the world population. Currently, xylose quantification in urine after gaxilose oral administration for the noninvasive diagnosis of hypolactasia is performed with the hand-operated nonautomatable phloroglucinol reaction. This work demonstrates t...

journal_title：BioMed research international

authors： Sánchez-Moreno I,Monsalve-Hernando C,Godino A,Illa L,Gaspar MJ,Muñoz GM,Díaz A,Martín JL,García-Junceda E,Fernández-Mayoralas A,Hermida C

更新日期：2017-01-01 00:00:00

abstract：:Cancer cells acquire unique secretome compositions that contribute to tumor development and metastasis. The aim of our study was to elucidate the biological processes involved in cervical cancer, by performing a proteomic analysis of the secretome from the following informative cervical cell lines: SiHa (HPV16+), HeLa...

journal_title：BioMed research international

authors： Kontostathi G,Zoidakis J,Makridakis M,Lygirou V,Mermelekas G,Papadopoulos T,Vougas K,Vlamis-Gardikas A,Drakakis P,Loutradis D,Vlahou A,Anagnou NP,Pappa KI

更新日期：2017-01-01 00:00:00

abstract：:Txndc9 (thioredoxin domain containing protein 9) has been shown to be involved in mammalian mitosis; however, its function in mammalian oocyte meiosis remains unclear. In this study, we initially found that Txndc9 is expressed during meiotic maturation of mouse oocytes and higher expression of Txndc9 mRNA and protein ...

journal_title：BioMed research international

authors： Ma F,Hou L,Yang L

更新日期：2017-01-01 00:00:00

abstract：:Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic data, biological pathw...

journal_title：BioMed research international

authors： Chen X,Wang Y,Wang P,Lian B,Li C,Wang J,Li X,Jiang W

更新日期：2015-01-01 00:00:00

abstract：:Regulation of hematopoietic stem cell release, migration, and homing from the bone marrow (BM) and of the mobilization pathway involves a complex interaction among adhesion molecules, cytokines, proteolytic enzymes, stromal cells, and hematopoietic cells. The identification of new mechanisms that regulate the traffick...

journal_title：BioMed research international

authors： Alvarez P,Carrillo E,Vélez C,Hita-Contreras F,Martínez-Amat A,Rodríguez-Serrano F,Boulaiz H,Ortiz R,Melguizo C,Prados J,Aránega A

更新日期：2013-01-01 00:00:00

abstract：:Artery calcification is a well-recognized predictor of late atherosclerotic complications. In the intima media, calcification starts with apoptosis of vascular smooth muscle cells (VSMCs) and the release of calcifying matrix vesicles with diameter of 0.5-15 μm that can be observed microscopically. In complicated plaqu...

journal_title：BioMed research international

authors： Chistiakov DA,Myasoedova VA,Melnichenko AA,Grechko AV,Orekhov AN

更新日期：2017-01-01 00:00:00

abstract：:New and innovative treatment strategies for cancer patients in the fields of immunotherapy and radiotherapy are rapidly developing in parallel. Among the most promising preclinical treatment approaches is combining immunotherapy with radiotherapy where early data suggest synergistic effects in several tumor model syst...

journal_title：BioMed research international

authors： Zeng J,Harris TJ,Lim M,Drake CG,Tran PT

更新日期：2013-01-01 00:00:00

abstract：:Increasing studies have revealed that long noncoding RNAs (lncRNAs) are not transcriptional noise but play important roles in the regulation of a wide range of biological processes, and the dysregulation of lncRNA genes is associated with disease development. Alzheimer's disease (AD) is a chronic neurodegenerative dis...

journal_title：BioMed research international

authors： Wan G,Zhou W,Hu Y,Ma R,Jin S,Liu G,Jiang Q

更新日期：2016-01-01 00:00:00

abstract：:We aimed to determine the effects of an 8 wk Hatha yoga training on blood glucose, insulin, lipid profiles, endothelial microparticles (EMPs), and inflammatory status in healthy, lean, and female Chinese subjects. A total of 30 healthy, female Chinese subjects were recruited and randomized into control or yoga practic...

journal_title：BioMed research international

authors： Chen N,Xia X,Qin L,Luo L,Han S,Wang G,Zhang R,Wan Z

更新日期：2016-01-01 00:00:00

abstract：Objective:It is sometimes difficult to obtain complete/partial response of large hepatocellular carcinoma (HCC) nodules by trans-arterial chemoembolization/embolization (TACE/TAE). The aim is retrospective investigation of tumor response of large HCC nodules (>7 cm) treated by the new TACE technique, repeated alternate...

journal_title：BioMed research international

authors： Irie T,Takahashi N,Kamoshida T,Kashimura J,Ariga H

更新日期：2020-01-19 00:00:00

abstract：:Background. Endemic areas of tegumentary leishmaniasis (TL) in Salta, Argentina, present some overlap zones with the geographical distribution of Chagas disease, with mixed infection cases being often detected. Objectives. The purpose of this study was to determine the magnitude of Leishmania sp. infection and potenti...

journal_title：BioMed research international

authors： Hoyos CL,Cajal SP,Juarez M,Marco JD,Alberti D'Amato AM,Cayo M,Torrejón I,Cimino RO,Diosque P,Krolewiecki AJ,Nasser JR,Gil JF

更新日期：2016-01-01 00:00:00

abstract：:Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the present study, antiproliferative potential of gedunin was evaluated in human embryonal carcinoma cells (NTERA-2, a cancer stem cell model) and peripheral blood mononuclear cells (PBMCs), using Sulforhodamine (SRB) and WST-1 assay...

journal_title：BioMed research international

authors： Tharmarajah L,Samarakoon SR,Ediriweera MK,Piyathilaka P,Tennekoon KH,Senathilake KS,Rajagopalan U,Galhena PB,Thabrew I

更新日期：2017-01-01 00:00:00

abstract：:In patients with sepsis and septic shock, the hemodynamic management in both early and later phases of these "organ dysfunction syndromes" is a key therapeutic component. It needs, however, to be differentiated between "early goal-directed therapy" (EGDT) as proposed for the first 6 hours of emergency department treat...

journal_title：BioMed research international

authors： Saugel B,Huber W,Nierhaus A,Kluge S,Reuter DA,Wagner JY

更新日期：2016-01-01 00:00:00

abstract：:Blood compatibility of metallocene polyethylene (mPE) was investigated after modifying the surface using hydrochloric acid. Contact angle of the mPE exposed to HCl poses a decrease in its value which indicates increasing wettability and better blood compatibility. Surface of mPE analyzed by using FTIR revealed no sign...

journal_title：BioMed research international

authors： Jaganathan SK,Mohandas H,Sivakumar G,Kasi P,Sudheer T,Avineri Veetil S,Murugesan S,Supriyanto E

更新日期：2014-01-01 00:00:00

abstract：:Introduction. The triangular fibrocartilage complex (TFCC) provides both mobility and stability of the radiocarpal joint. TFCC lesions are difficult to diagnose due to the complex anatomy. The standard treatment for TFCC lesions is arthroscopy, posing surgery-related risks onto the patients. This feasibility study aim...

journal_title：BioMed research international

authors： Hammer N,Hirschfeld U,Strunz H,Werner M,Wolfskämpf T,Löffler S

更新日期：2017-01-01 00:00:00

abstract：:Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen...

journal_title：BioMed research international

authors： Wu J,Xia S,Kalionis B,Wan W,Sun T

更新日期：2014-01-01 00:00:00

abstract：Purpose:Ischemic ocular disorders may be treated by hypervolemic hemodilution. The presumed therapeutic benefit is based on a volume effect and improved rheological factors. The aim was to investigate the acute effect of intravenous hydroxyethyl starch on retrobulbar hemodynamics in patients with nonarteritic anterior ...

journal_title：BioMed research international

authors： Bienert M,Plange N,Remky A,Arend KO,Kuerten D

更新日期：2018-02-06 00:00:00

abstract：:Besides the pinpointing of individual disease-related genes, associating protein complexes to human inherited diseases is also of great importance, because a biological function usually arises from the cooperative behaviour of multiple proteins in a protein complex. Moreover, knowledge about disease-related protein co...

journal_title：BioMed research international

authors： Jacquemin T,Jiang R

更新日期：2013-01-01 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expre...

journal_title：BioMed research international

authors： Zhang Y,Lin Y,Liu Q,Yuan X,Mao A,Liu Y,Li Q,Zheng J,Hu B,Yu F

更新日期：2018-01-16 00:00:00

abstract：:Introduction and Objectives. Neutrophil-to-lymphocyte ratio (NLR) has been suggested to be a simple marker of the systemic inflammatory response in critical care patients. We previously assessed the utility of NLR as a biomarker to predict tumor recurrence and cancer death in bladder cancer patients who underwent radi...

journal_title：BioMed research international

authors： Ohtake S,Kawahara T,Kasahara R,Ito H,Osaka K,Hattori Y,Teranishi JI,Makiyama K,Mizuno N,Umemoto S,Miyoshi Y,Nakaigawa N,Miyamoto H,Yao M,Uemura H

更新日期：2016-01-01 00:00:00

abstract：:Detecting breast cancer at early stages can be challenging. Traditional mammography and tissue microarray that have been studied for early breast cancer detection and prediction have many drawbacks. Therefore, there is a need for more reliable diagnostic tools for early detection of breast cancer due to a number of fa...

journal_title：BioMed research international

authors： Zhang F,Deng Y,Drabier R

更新日期：2013-01-01 00:00:00

abstract：:It has been described renal damage in rats with vascular calcification. The organic anion transporter 5 (Oat5) is only expressed in kidney, and its urinary excretion was proposed as potential early biomarker of renal injury. The aim of this study was to evaluate the Oat5 renal expression and its urinary excretion in a...

journal_title：BioMed research international

authors： Hazelhoff MH,Bulacio RP,Torres AM

更新日期：2013-01-01 00:00:00

abstract：:Plant-associated bacteria provide important services to host plants. Environmental factors such as cultivar type and pedoclimatic conditions contribute to shape their diversity. However, whether these environmental factors may influence the plant growth promoting (PGP) potential of the root-associated bacteria is not ...

journal_title：BioMed research international

authors： Marasco R,Rolli E,Fusi M,Cherif A,Abou-Hadid A,El-Bahairy U,Borin S,Sorlini C,Daffonchio D

更新日期：2013-01-01 00:00:00

abstract：:Ablative therapies have been utilized with increasing frequency for the treatment of Barrett's esophagus with and without dysplasia. Multiple modalities are available for topical ablation of the esophagus, but radiofrequency ablation (RFA) remains the most commonly used. There have been significant advances in techniq...

journal_title：BioMed research international

authors： Tuttle R,Nurkin SJ,Hochwald SN

更新日期：2014-01-01 00:00:00