Acute Effect of Hypervolemic Hemodilution on Retrobulbar Hemodynamics in Anterior Ischemic Optic Neuropathy.

abstract：:Mutations in genes encoding isocitrate dehydrogenase isoforms 1 (IDH1) and 2 (IDH2) have been associated with good prognosis for patients with brain neoplasias and have been commonly found together with mutated TP53 gene. To determine the prevalence of IDH1, IDH2, and TP53 mutations and their impact on overall surviva...

journal_title：BioMed research international

authors： Stancheva G,Goranova T,Laleva M,Kamenova M,Mitkova A,Velinov N,Poptodorov G,Mitev V,Kaneva R,Gabrovsky N

更新日期：2014-01-01 00:00:00

abstract：:Introduction and Objectives. Neutrophil-to-lymphocyte ratio (NLR) has been suggested to be a simple marker of the systemic inflammatory response in critical care patients. We previously assessed the utility of NLR as a biomarker to predict tumor recurrence and cancer death in bladder cancer patients who underwent radi...

journal_title：BioMed research international

authors： Ohtake S,Kawahara T,Kasahara R,Ito H,Osaka K,Hattori Y,Teranishi JI,Makiyama K,Mizuno N,Umemoto S,Miyoshi Y,Nakaigawa N,Miyamoto H,Yao M,Uemura H

更新日期：2016-01-01 00:00:00

abstract：:The crude ethanolic extract from aerial parts of Pothomorphe umbellata L. (Piperaceae) and fractions obtained by partitions sequentially among water-methanol, methylene chloride, and ethyl acetate, as well as the major constituent, 4-nerolidylcatechol, were, respectively, evaluated and evidenced for antioxidant and cy...

journal_title：BioMed research international

authors： Lopes AP,Bagatela BS,Rosa PC,Nanayakkara DN,Tavares Carvalho JC,Maistro EL,Bastos JK,Perazzo FF

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Maternal thyroid dysfunction in early pregnancy may increase the risk of adverse pregnancy complications and neurocognitive deficiencies in the developing fetus. Currently, some researchers demonstrated that body mass index (BMI) is associated with thyroid function in nonpregnant population. Hence, the Ameri...

journal_title：BioMed research international

authors： Han C,Li C,Mao J,Wang W,Xie X,Zhou W,Li C,Xu B,Bi L,Meng T,Du J,Zhang S,Gao Z,Zhang X,Yang L,Fan C,Teng W,Shan Z

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:It is well established that the Mediterranean and Arab populations are at high risk for thalassemias in general and for alpha-thalassemia in particular. Yet, reports on alpha-thalassemia in Lebanon are still lacking. In this study, we aim at assessing the incidence of alpha-thalassemia in the Lebanese popula...

journal_title：BioMed research international

authors： Farra C,Daher R,Badra R,el Rafei R,Bejjany R,Charafeddine L,Yunis K

更新日期：2015-01-01 00:00:00

abstract：:Heat shock proteins 70 and heat shock proteins 90 (Hsp70/90) have been implicated in many crucial steps of carcinogenesis: stabilizing oncogenic proteins, inhibiting programmed cell death and replicative senescence, induction of tumor angiogenesis, and activation of the invasion and metastasis. Plenty of cancer relate...

journal_title：BioMed research international

authors： Wang H,Tan MS,Lu RC,Yu JT,Tan L

更新日期：2014-01-01 00:00:00

abstract：:Detecting breast cancer at early stages can be challenging. Traditional mammography and tissue microarray that have been studied for early breast cancer detection and prediction have many drawbacks. Therefore, there is a need for more reliable diagnostic tools for early detection of breast cancer due to a number of fa...

journal_title：BioMed research international

authors： Zhang F,Deng Y,Drabier R

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a multisystemic granulomatous disorder characterized by multiple noncaseating granulomas involving intrathoracic lymph nodes and lung parenchyma. Recently, the use of anti-tumor necrosis factor alpha (anti-TNFα) agents has been introduced for therapy of chronic and refractory sarcoidosis wit...

journal_title：BioMed research international

authors： Galli F,Lanzolla T,Pietrangeli V,Malviya G,Ricci A,Bruno P,Ragni P,Scopinaro F,Mariotta S,Signore A

更新日期：2015-01-01 00:00:00

abstract：:The 13 million nurses worldwide constitute most of the global healthcare workforce and are uniquely positioned to engage with others to address disparities in healthcare to achieve the goal of better health for all. A new vision for nurses involves active participation and collaboration with international colleagues a...

journal_title：BioMed research international

authors： Premji SS,Hatfield J

更新日期：2016-01-01 00:00:00

abstract：:Background. The chronic recommendation of pediatric drugs could exhibit erosive and cariogenic problems. Objective. To evaluate the effects of different pediatric drugs on the color stability of various restorative materials. Methods. Five specimens (1 mm × 3 mm) were prepared and immersed in ten different pediatric d...

journal_title：BioMed research international

authors： Tüzüner T,Turgut S,Baygin O,Yilmaz N,Tuna EB,Ozen B

更新日期：2017-01-01 00:00:00

abstract：:Aim. The aim of the study was to compare the incidence of "de novo" overactive bladder (OAB) after sling surgeries and Burch procedure and to analyze the effect of the preoperative bladder volume on the incidence of this condition. Methods. This prospective trial included 290 female patients with stress urinary incont...

journal_title：BioMed research international

authors： Ciećwież S,Chełstowski K,Brodowska A,Ptak M,Kotlęga D,Starczewski A

更新日期：2019-02-12 00:00:00

abstract：:Q192R and L55M polymorphism were considered to be associated with the development of multiple cancers. Nevertheless, the results of these researches were inconclusive and controversial. Therefore, we conducted a meta-analysis of all eligible case-control studies to assess the association between PON1 (Q192R and L55M) ...

journal_title：BioMed research international

authors： Pan X,Huang L,Li M,Mo D,Liang Y,Liu Z,Huang Z,Huang L,Liu J,Zhu B

更新日期：2019-07-28 00:00:00

abstract：:Contrast-induced nephropathy (CIN) remains a leading cause of iatrogenic acute kidney injury, as the usage of contrast media for imaging and intravascular intervention keeps expanding. Diabetes is an important predisposing factor for CIN, particularly in patients with renal functional impairment. Renal hypoxia, combin...

journal_title：BioMed research international

authors： Heyman SN,Rosenberger C,Rosen S,Khamaisi M

更新日期：2013-01-01 00:00:00

abstract：:Dental modeling resins have been developed for use in areas where highly precise resin structures are needed. The manufacturers claim that these polymethyl methacrylate/methyl methacrylate (PMMA/MMA) resins show little or no shrinkage after polymerization. This study examined the polymerization shrinkage of five denta...

journal_title：BioMed research international

authors： Kwon TY,Ha JY,Chun JN,Son JS,Kim KH

更新日期：2014-01-01 00:00:00

abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

journal_title：BioMed research international

authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

更新日期：2015-01-01 00:00:00

abstract：:Persistent catecholamine-resistant shock in children causes severe morbidity and mortality. We aimed to analyze the association between hemodynamics and serum lactate at different time points and 28-day mortality in children with persistent catecholamine-resistant shock. Methods. Twenty-six children with persistent ca...

journal_title：BioMed research international

authors： Lee EP,Chu SC,Hsia SH,Chen KF,Chan OW,Lin CY,Su YT,Lin JJ,Wu HP

更新日期：2020-06-19 00:00:00

abstract：:Hitherto, limited clinical impact has been achieved in the treatment of glioblastoma (GBMs). Although phytochemicals found in medicinal herbs can provide mankind with new therapeutic remedies, single agent intervention has failed to bring the expected outcome in clinical trials. Therefore, combinations of several agen...

journal_title：BioMed research international

authors： Elkady AI,Hussein RA,Abu-Zinadah OA

更新日期：2014-01-01 00:00:00

abstract：:Carbonic anhydrases (CAs) are enzymes that catalyse the reversible hydration of CO2 to bicarbonate. CA XII is considered a potential biomarker of tumor cells and a promising target for specific therapies. The aim of the current study was to develop new monoclonal antibodies (MAbs) against human recombinant CA XII and ...

journal_title：BioMed research international

authors： Dekaminaviciute D,Lasickiene R,Parkkila S,Jogaite V,Matuliene J,Matulis D,Zvirbliene A

更新日期：2014-01-01 00:00:00

abstract：:Historically, the colistin has been thought to kill bacteria through membrane lysis. Here, we present an alternative mechanism that colistin induces rapid Paenibacillus polymyxa death through reactive oxygen species production. This significantly augments our understanding of the mechanism of colistin action, which is...

journal_title：BioMed research international

authors： Yu Z,Zhu Y,Qin W,Yin J,Qiu J

更新日期：2017-01-01 00:00:00

abstract：Background:Fingertips are a common site for hand injuries. The ideal substitute for fingertip pulp is tissue that matches texturally with minimal donor site morbidity. We described anatomical findings from cadaveric studies and the reliability of the palmar ulnar artery perforator (PUAP) free flap techniques for the re...

journal_title：BioMed research international

authors： Pak CS,Jeon JI,Myung Y,Lee YK,Kim BJ,Jeong JH,Kim BK

更新日期：2018-05-09 00:00:00

abstract：:The present study was proposed to investigate the toxicological and prophylactic potential of ethanolic extracts of Rosa damascena and Nymphaea alba and their mixture in albino mice. For toxicity study, three different doses of plant extracts were orally administrated to three groups of mice for 14 successive days. Bl...

journal_title：BioMed research international

authors： Batool R,Kalsoom A,Akbar I,Arshad N,Jamil N

更新日期：2018-01-23 00:00:00

abstract：:Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a pressure overload-induced early and late stage heart fai...

journal_title：BioMed research international

authors： Wang X,Song C,Zhou X,Han X,Li J,Wang Z,Shang H,Liu Y,Cao H

更新日期：2017-01-01 00:00:00

abstract：Background and Aims:The NF-κB pathway has been implicated in the genetic aetiology of psoriatic disease. However, since most patients with arthritis have psoriasis, discerning the genetic contributions to both aspects of psoriatic disease is not easy. Our aim was to study the association of common polymorphisms in gene...

journal_title：BioMed research international

authors： Coto-Segura P,Coto E,González-Lara L,Alonso B,Gómez J,Cuesta-Llavona E,Queiro R

更新日期：2019-11-11 00:00:00

abstract：:Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequ...

journal_title：BioMed research international

authors： Lakusic N,Mahovic D,Kruzliak P,Cerkez Habek J,Novak M,Cerovec D

更新日期：2015-01-01 00:00:00

abstract：:The present study evaluated the anti-inflammatory and analgesic effects of the superoxide dismutase mimetic agent tempol in superoxide anion-induced pain and inflammation. Mice were treated intraperitoneally with tempol (10-100 mg/kg) 40 min before the intraplantar injection of a superoxide anion donor, potassium supe...

journal_title：BioMed research international

authors： Bernardy CCF,Zarpelon AC,Pinho-Ribeiro FA,Calixto-Campos C,Carvalho TT,Fattori V,Borghi SM,Casagrande R,Verri WA Jr

更新日期：2017-01-01 00:00:00

abstract：:A growing body of evidence has indicated that high-fat diet-induced nonalcoholic fatty liver disease is usually accompanied by oxidized low-density lipoprotein (ox-LDL) deposited in the liver. The current study aimed to investigate the effect of quercetin on high-fat diet-induced ox-LDL accumulation in the liver and t...

journal_title：BioMed research international

authors： Liu L,Gao C,Yao P,Gong Z

更新日期：2015-01-01 00:00:00

abstract：Introduction:We investigated the proportion of myeloid-derived suppressor cells (MDSCs) and their subsets in patients with rheumatic diseases and clarified the association between these cells and the patient clinical data. Methods:Patients with rheumatic diseases and healthy controls were recruited. The clinical chara...

journal_title：BioMed research international

authors： Zhu J,Chen S,Wu L,Wang R,Zheng S,Zhao D,Wang X,Li J

更新日期：2018-06-26 00:00:00

abstract：Purpose:Computer-aided diagnosis (CAD) can aid in improving diagnostic level; however, the main problem currently faced by CAD is that it cannot obtain sufficient labeled samples. To solve this problem, in this study, we adopt a generative adversarial network (GAN) approach and design a semisupervised learning algorith...

journal_title：BioMed research international

authors： Zheng G,Han G,Soomro NQ,Ma L,Zhang F,Zhao Y,Zhao X,Zhou C

更新日期：2019-04-15 00:00:00

abstract：:Guanosine is an important building block for supramolecular gels owing to the unique self-assembly property that results from the unique hydrogen bond acceptors and donor groups. Guanosine-derived supramolecular hydrogels have promise in the fields of drug delivery, targeted release, tissue engineering applications, e...

journal_title：BioMed research international

authors： Chen M,Lin W,Hong L,Ji N,Zhao H

更新日期：2019-06-13 00:00:00

abstract：:Severe acute pancreatitis (SAP) results in high mortality. This is partly because of early multiple organ dysfunction syndromes that are usually caused by systemic inflammatory response syndrome (SIRS). Many studies have reported the beneficial effects of emodin against SAP with SIRS. However, the exact mechanism unde...

journal_title：BioMed research international

authors： Wang GJ,Wang Y,Teng YS,Sun FL,Xiang H,Liu JJ,Xia SL,Zhang GX,Chen HL,Shang D

更新日期：2016-01-01 00:00:00