Systematic analysis of the associations between adverse drug reactions and pathways.

abstract：:Selenium is an essential trace element, which has certain antioxidant properties. Na2SeO3 is toxic, and its use is limited. SeMet, as an organic selenium, is less toxic than Na2SeO3. In this experiment, different concentrations of Na2SeO3 and SeMet were added to MEA and PDA media to observe the effect of selenium on t...

journal_title：BioMed research international

authors： Zhao W,Zhai F,Han J

更新日期：2020-04-26 00:00:00

abstract：:Objective. Obesity and obstructive sleep apnea (OSA) are closely interconnected conditions both leading to high cardiovascular risk. Inactivity is frequent and physical activity programs remain difficult in these patients. We investigated the acute feasibility of two neuromuscular electrical stimulation (NMES) modalit...

journal_title：BioMed research international

authors： Vivodtzev I,Maffiuletti NA,Borel AL,Grangier A,Wuyam B,Tamisier R,Pépin JL

更新日期：2017-01-01 00:00:00

abstract：:This study shows that membrane-associated cytoskeletal protein structures and the erythrocyte morphology undergo profound changes during hypoxia. Hypoxia also intensified oxidative processes in the lipid phase of the bilayer of red blood cell membranes. Sodium nitroprusside impaired the morphology of red blood cells a...

journal_title：BioMed research international

authors： Revin VV,Gromova NV,Revina ES,Prosnikova KV,Revina NV,Bochkareva SS,Stepushkina OG,Grunyushkin IP,Tairova MR,Incina VI

更新日期：2019-12-07 00:00:00

abstract：:Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells. While numerous SL...

journal_title：BioMed research international

authors： Li XJ,Mishra SK,Wu M,Zhang F,Zheng J

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to detect oral bacteremia and offer the antibiotic resistance patterns. Bacterial resistance pattern was evaluated in 50 patients. A spectrophotometer device equipped with UV and electrophoresis of the extracted samples on agarose gel for antibiogram test were used. PCR test 15 minutes after ...

journal_title：BioMed research international

authors： Rezazadeh F,Azad A,Khorami A,Modaresi F,Rezaie Z

更新日期：2020-10-01 00:00:00

abstract：:Background. Stenotrophomonas maltophilia bacteremia (SMB) is the most perilous situation as compared to other types of S. maltophilia infection. The present study aimed to investigate the clinical features, distribution, drug resistance, and predictors of survival of SMB in a tertiary-care hospital of China. Methods. ...

journal_title：BioMed research international

authors： Chen Y,Suo J,Du M,Chen L,Liu Y,Wang L,Liang Z

更新日期：2019-12-09 00:00:00

abstract：:The purpose of this study was to assess the impact of 3 months of aromatase inhibition together with progestin add-back on ovarian endometrioma size. This prospective cohort study was performed at University Medical Center (UC San Diego). Women trying to conceive were excluded. After informed consent, all women were t...

journal_title：BioMed research international

authors： Agarwal SK,Foster WG

更新日期：2015-01-01 00:00:00

abstract：:Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, and appendiceal mucosae. Oral mucosa grafts, especially buccal muco...

journal_title：BioMed research international

authors： Xiong S,Wang J,Zhu W,Yang K,Ding G,Li X,Eun DD

更新日期：2020-07-27 00:00:00

abstract：:Exposure to a variety of environmental factors such as salinity, drought, metal toxicity, extreme temperature, air pollutants, ultraviolet-B (UV-B) radiation, pesticides, and pathogen infection leads to subject oxidative stress in plants, which in turn affects multiple biological processes via reactive oxygen species ...

journal_title：BioMed research international

authors： Xie X,He Z,Chen N,Tang Z,Wang Q,Cai Y

更新日期：2019-05-08 00:00:00

abstract：Background:Neonatal jaundice is common a clinical problem worldwide. Globally, every year, about 1.1 million babies develop severe hyperbilirubinemia with or without bilirubin encephalopathy and the vast majority reside in sub-Saharan Africa and South Asia. Strategies and information on determinants of neonatal jaundic...

journal_title：BioMed research international

authors： Asefa GG,Gebrewahid TG,Nuguse H,Gebremichael MW,Birhane M,Zereabruk K,Zemicheal TM,Hailay A,Abrha WA,Hadera SA,Hailu AG,Beyene BH,Dagnazgi EA,Tekulu FG,Welay F

更新日期：2020-10-21 00:00:00

abstract：:A series of sulfonamide-bearing azaheterocyclic Schiff base derivatives 3(a-j) were synthesized as carbonic anhydrase inhibitors. The substituted benzene sulfonyl chlorides 1(a-d) were reacted with N2H4 to get aromatic sulfonyl hydrazides 2(a-d). The intermediate hydrazides 2(a-d) were treated with substituted aldehyd...

journal_title：BioMed research international

authors： Abas M,Rafique H,Shamas S,Roshan S,Ashraf Z,Iqbal Z,Raza H,Hassan M,Afzal K,Rizvanov AA,Asad MHHB

更新日期：2020-02-20 00:00:00

abstract：:Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease associated with accelerated atherosclerosis and increased risk of cardiovascular (CV) disease. AS patients also display a high prevalence of features clustered under the name of metabolic syndrome (MeS). Anti-TNF- α therapy was found to be effecti...

journal_title：BioMed research international

authors： Genre F,López-Mejías R,Miranda-Filloy JA,Ubilla B,Carnero-López B,Blanco R,Pina T,González-Juanatey C,Llorca J,González-Gay MA

更新日期：2014-01-01 00:00:00

abstract：:The use of endotamponade agents has gained a major role in the management of macular complications of high myopia. Myopic foveoschisis and macular hole are the main macular complication of pathologic myopia, this growing condition that is a main cause of visual loss, especially in patients at a younger age. We discuss...

journal_title：BioMed research international

authors： Valldeperas X,Lorenzo-Carrero J

更新日期：2014-01-01 00:00:00

abstract：:To further understand the potential expression relationships of miRNAs in miRNA gene clusters and gene families, a global analysis was performed in 4 paired tumor (breast cancer) and adjacent normal tissue samples using deep sequencing datasets. The compositions of miRNA gene clusters and families are not random, and ...

journal_title：BioMed research international

authors： Guo L,Yang S,Zhao Y,Zhang H,Wu Q,Chen F

更新日期：2014-01-01 00:00:00

abstract：:The search for effective methods of myocardial cytoprotection against ischemia is the most significant issue in modern cardiology and cardiac surgery. Glucocorticoids are deemed very strong modulators of inflammatory response and thus can potentially protect heart muscle from postreperfusion injury and myocardial isch...

journal_title：BioMed research international

authors： Kuropka P,Dobrzyński M,Gamian A,Gostomska-Pampuch K,Kuryszko J,Całkosiński I

更新日期：2017-01-01 00:00:00

abstract：:Several studies have compared molecular components between red and white skeletal muscles in mammals. However, mammalian skeletal muscles are composed of mixed types of muscle fibers. In the current study, we analyzed and compared the distributions of titin, lipid, phosphate ions, and fatty acid levels in red and whit...

journal_title：BioMed research international

authors： Wu MP,Chang NC,Chung CL,Chiu WC,Hsu CC,Chen HM,Sheu JR,Jayakumar T,Chou DS,Fong TH

更新日期：2018-11-18 00:00:00

abstract：:There is a need to scientifically validate the claim that wild species of medicinal plants are more potent than the cultivated plants. Thus, this study evaluated the phytochemical and antioxidant properties of wild and cultivated Alepidea amatymbica. Acetone, methanol, and water extracts of the rhizome of wild and cul...

journal_title：BioMed research international

authors： Mangoale RM,Afolayan AJ

更新日期：2020-04-13 00:00:00

abstract：Introduction:Even today, despite medical progress and intensive health education, odontogenic infections leading to surgical intervention and hospitalization are common in children and young people. The aim of this study was to give a detailed overview of clinical and economic data on children and young people treated ...

journal_title：BioMed research international

authors： Doll C,Carl F,Neumann K,Voss JO,Hartwig S,Waluga R,Heiland M,Raguse JD

更新日期：2018-08-26 00:00:00

abstract：:The main aim was to analyse the associations between several physical fitness variables and bone parameters in a sample of elderly people. 129 participants (94 females and 35 males, 76.2 ± 5.4 y) from the EXERNET cohort of Zaragoza (Spain) were included in the study. Physical fitness was assessed using the Senior Fitn...

journal_title：BioMed research international

authors： Moradell A,Gómez-Cabello A,Gómez-Bruton A,Muniz-Pardos B,Puyalto JM,Matute-Llorente A,Gónzalez-Agüero A,Ara I,Casajús JA,Vicente-Rodríguez G

更新日期：2020-07-15 00:00:00

abstract：:The goal of this study was to analyse perceptually and acoustically the voices of patients with Unilateral Vocal Fold Paralysis (UVFP) and compare them to the voices of normal subjects. These voices were analysed perceptually with the GRBAS scale and acoustically using the following parameters: mean fundamental freque...

journal_title：BioMed research international

authors： Jesus LM,Martinez J,Hall A,Ferreira A

更新日期：2015-01-01 00:00:00

abstract：:Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmis...

journal_title：BioMed research international

authors： Reis Machado J,da Silva MV,Cavellani CL,dos Reis MA,Monteiro ML,Teixeira Vde P,Miranda Corrêa RR

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee osteoarthritis. MATERIALS AND METHODS:A comparison of the outcomes of randomized controlled trials (RCTs) included ...

journal_title：BioMed research international

authors： Milants C,Bruyère O,Kaux JF

更新日期：2017-01-01 00:00:00

abstract：:Human dental pulp stem cells (DPSCs) hold great promise in bone regeneration. However, the exact mechanism of osteogenic differentiation of DPSCs remains unknown, especially the role of exosomes played in. The DPSCs were cultured and received osteogenic induction; then, exosomes from osteogenic-induced DPSCs (OI-DPSC-...

journal_title：BioMed research international

authors： Xie L,Guan Z,Zhang M,Lyu S,Thuaksuban N,Kamolmattayakul S,Nuntanaranont T

更新日期：2020-09-28 00:00:00

abstract：:This study tested the hypothesis that sensitivity of Escherichia coli to lactic acid at concentrations relevant for fermented sausages (pH 4.6, 150 mM lactic acid, aw = 0.92, temperature = 20 or 27°C) increases with increasing growth rate. For E. coli strain 683 cultured in TSB in chemostat or batch, subsequent inacti...

journal_title：BioMed research international

authors： Lindqvist R,Barmark G

更新日期：2014-01-01 00:00:00

abstract：:RAW264.7 is a macrophage strain derived from mice tumour and shows a significant ability in antigen uptake. Real-time quantitative PCR (RT-qPCR) is one of the most commonly used methods in gene studies and requires suitable reference genes to normalize and quantitate the expression of gene of interest with sensitivity...

journal_title：BioMed research international

authors： Bao Z,Huang Y,Chen J,Wang Z,Qian J,Xu J,Zhao Y

更新日期：2019-05-16 00:00:00

abstract：:We performed a retrospective review of 40 consecutive modern cementless THAs with 65-month mean followup in 34 patients under the age of 30 primarily for diagnoses other than inflammatory arthritis. We found acceptable functional improvement and radiographic outcomes at mean 5-year followup. We found a high transfusio...

journal_title：BioMed research international

authors： Gililland JM,Anderson LA,Erickson J,Pelt CE,Peters CL

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Sarcopenia is the presence of low muscle mass and low muscle function. The aim of this study was to establish cutoffs for low muscle mass using three published methods and to compare the prevalence of sarcopenia in older Australians. METHODS:Gender specific cutoffs levels were identified for low muscle mass...

journal_title：BioMed research international

authors： Yu S,Appleton S,Adams R,Chapman I,Wittert G,Visvanathan T,Visvanathan R

更新日期：2014-01-01 00:00:00

abstract：:A set of optical models associated with blood cells are introduced in this paper. All of these models are made up of different parts possessing symmetries. The wrapped phase images as well as the unwrapped ones from two orthogonal directions related to some of these models are obtained by simulation technique. Because...

journal_title：BioMed research international

authors： Ji Y,Liang M,Hua T,Xu Y,Xin Z,Wang Y

更新日期：2015-01-01 00:00:00

abstract：:A metabolic disorder is considered one of the hallmarks of cancer. Multiple differentially expressed metabolic genes have been identified in colon cancer (CC), and their biological functions and prognostic values have been well explored. The purpose of the present study was to establish a metabolic signature to optimi...

journal_title：BioMed research international

authors： Luo D,Shan Z,Liu Q,Cai S,Li Q,Li X

更新日期：2020-11-17 00:00:00

abstract：:Plantar fasciitis is a cause of chronic pain under the heel and bottom of the foot. One of the treatments to reduce pain consists of using plantar orthoses to address specific imbalances during foot placement or gait. The aim of the present study was to determine if reduction of pain with a treatment based on plantar ...

journal_title：BioMed research international

authors： Moyne-Bressand S,Dhieux C,Dousset E,Decherchi P

更新日期：2018-12-12 00:00:00