Abstract:
:This study shows that membrane-associated cytoskeletal protein structures and the erythrocyte morphology undergo profound changes during hypoxia. Hypoxia also intensified oxidative processes in the lipid phase of the bilayer of red blood cell membranes. Sodium nitroprusside impaired the morphology of red blood cells and altered quantitative and qualitative composition of membrane-skeletal proteins. The findings suggest that hypoxia causes changes at all levels of red blood cell organization, which can cause the functional disorders of hemoglobin oxygen-transporting properties and, eventually, the complete degradation of red blood cells. The use of flavonoids has a protective effect against hypoxia.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Revin VV,Gromova NV,Revina ES,Prosnikova KV,Revina NV,Bochkareva SS,Stepushkina OG,Grunyushkin IP,Tairova MR,Incina VIdoi
10.1155/2019/6758017subject
Has Abstractpub_date
2019-12-07 00:00:00pages
6758017eissn
2314-6133issn
2314-6141journal_volume
2019pub_type
杂志文章abstract::Cardiogenic shock (CS) is uncommon in patients suffering from acute myocardial infarction (AMI). Long-term outcome and adverse predictors for outcomes in AMI patients with CS receiving percutaneous coronary interventions (PCI) are unclear. A total of 482 AMI patients who received PCI were collected, including 53 CS an...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/8530539
更新日期:2017-01-01 00:00:00
abstract::Information and communications technology (ICT) could support ambient assisted living (AAL) based interventions to provide support to informal caregivers of people with dementia, especially when they need to cope with their feelings of overburden or isolation. An e-learning platform (understAID application) was tested...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2016/5726465
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:The PiCCO transpulmonary thermodilution technique provides two indices of cardiac systolic function, the cardiac function index (CFI) and the global ejection fraction (GEF). Both appear to be correlated with left ventricular ejection fraction (LVEF) measured by echocardiography in patients with circulatory...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/598029
更新日期:2014-01-01 00:00:00
abstract::Aerobic granulation of activated sludge was successfully achieved in a full-scale sequencing batch reactor (SBR) with 50,000 m(3) d(-1) for treating a town's wastewater. After operation for 337 days, in this full-scale SBR, aerobic granules with an average SVI30 of 47.1 mL g(-1), diameter of 0.5 mm, and settling veloc...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/268789
更新日期:2014-01-01 00:00:00
abstract::The present study was proposed to investigate the toxicological and prophylactic potential of ethanolic extracts of Rosa damascena and Nymphaea alba and their mixture in albino mice. For toxicity study, three different doses of plant extracts were orally administrated to three groups of mice for 14 successive days. Bl...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4543723
更新日期:2018-01-23 00:00:00
abstract:Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3845780
更新日期:2019-12-14 00:00:00
abstract::Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain. It has not been fully examined yet how nerve conduction inhibitions by l...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/540238
更新日期:2014-01-01 00:00:00
abstract::Due to anthropogenic activities the relative concentrations of cadmium and manganese have increased in the marine environment. Cephalopods are able to accumulate such metals and, as inhabitant of coastal waters, Octopus vulgaris is continuously exposed to anthropogenic activities. Since no study is available on the ef...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/437328
更新日期:2015-01-01 00:00:00
abstract::The aim of the present study was to determine if the Ki-67 labelling index reflects invasiveness of pituitary adenoma and to evaluate IL-17A concentration in blood serum of pituitary adenoma patients. The study was conducted in the Hospital of Lithuanian University of Health Sciences. All pituitary adenomas were analy...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7490585
更新日期:2018-05-31 00:00:00
abstract::Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic data, biological pathw...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/670949
更新日期:2015-01-01 00:00:00
abstract::Effects of ketamine and lidocaine on electroencephalographic (EEG) changes were evaluated in minimally anaesthetized dogs, subjected to electric stimulus. Six dogs were subjected to six treatments in a crossover design with a washout period of one week. Dogs were subjected to intravenous boluses of lidocaine 2 mg/kg, ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/305367
更新日期:2015-01-01 00:00:00
abstract::Objective. This study was aimed at analyzing the expressions of long noncoding RNAs (lncRNAs) in Botulinum Toxin Type A (BoNTA) treated human dermal fibroblasts (HDFs) in vitro. Methods. We used RNA sequencing to characterize the lncRNAs and mRNAs transcriptome in the control and BoNTA treated group, in conjunction wi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2957941
更新日期:2017-01-01 00:00:00
abstract::In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/365982
更新日期:2014-01-01 00:00:00
abstract:Results:The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (Dmax) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for Dmean of the heart and left ventricle ...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2020/7131590
更新日期:2020-03-26 00:00:00
abstract::Mind-body practices (MBP) are known to induce electrophysiological and morphological changes, whereas reports related to changes of neurotrophins are surprisingly scarce. Consequently, in the current paper, we focused on the Quadrato motor training (QMT), a newly developed whole-body movement-based MBP, which has been...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/275062
更新日期:2015-01-01 00:00:00
abstract::Bayesian analysis was used to estimate the pig's and herd's true prevalence of enteropathogenic Yersinia in serum samples collected from Finnish pig farms. The sensitivity and specificity of the diagnostic test were also estimated for the commercially available ELISA which is used for antibody detection against entero...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/931542
更新日期:2015-01-01 00:00:00
abstract:Background:Circular RNA (circRNA) is a noncoding RNA that forms a closed-loop structure, and its abnormal expression may cause disease. We aimed to find potential network for circRNA-related competitive endogenous RNA (ceRNA) in atrial fibrillation (AF). Methods:The circRNA, miRNA, and mRNA expression profiles in the ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8037273
更新日期:2020-09-29 00:00:00
abstract::The aim of this study was to detect oral bacteremia and offer the antibiotic resistance patterns. Bacterial resistance pattern was evaluated in 50 patients. A spectrophotometer device equipped with UV and electrophoresis of the extracted samples on agarose gel for antibiogram test were used. PCR test 15 minutes after ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9502959
更新日期:2020-10-01 00:00:00
abstract::Increased sugar consumption, especially fructose, is strongly related to the development of type 2 diabetes (T2D) and metabolic syndrome. The aim of this study was to evaluate long term effects of fructose supplementation on Wistar rats. Three-week-old male rats were randomly divided into 2 groups: control (C; n = 14)...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2494067
更新日期:2017-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2013/783690.]. ...
journal_title:BioMed research international
pub_type: 已发布勘误
doi:10.1155/2016/8693826
更新日期:2016-01-01 00:00:00
abstract::Background. Central systolic blood pressure (CSBP) has prognostic significance and simplified devices for its estimation have been introduced recently. The aim of this study was to assess the achievement of the target CSBP in treated hypertensive patients. Subjects and Methods. One hundred patients with well-controlle...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/8158974
更新日期:2017-01-01 00:00:00
abstract::Ambient assisted living (AAL) aims to help older persons "age-in-place" and manage everyday activities using intelligent and pervasive computing technology. AAL research, however, has yet to explore how AAL might support or collaborate with informal care partners (ICPs), such as relatives and friends, who play importa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/720483
更新日期:2015-01-01 00:00:00
abstract::The main aim was to analyse the associations between several physical fitness variables and bone parameters in a sample of elderly people. 129 participants (94 females and 35 males, 76.2 ± 5.4 y) from the EXERNET cohort of Zaragoza (Spain) were included in the study. Physical fitness was assessed using the Senior Fitn...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6930682
更新日期:2020-07-15 00:00:00
abstract::Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/147196
更新日期:2015-01-01 00:00:00
abstract:Background:Focal hyperhidrosis mostly affects the axillae, hands, feet, and face. For the management, several techniques are used. The aim of this study was to investigate the effects of direct current administration on the hyperhidrosis disease severity scale (HDSS) in patients with axillary hyperhidrosis that have va...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/3232015
更新日期:2019-10-31 00:00:00
abstract:OBJECTIVE:Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with eccentric versus traditio...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/398960
更新日期:2014-01-01 00:00:00
abstract:Background:A deficiency in steroid 5α-reductase type 2 is an autosomal recessive disorder. Affected individuals manifested ambiguous genitalia, which is caused by decreased dihydrotestosterone (DHT) synthesis in the fetus. Methods:We analyzed 25 patients with 5α-reductase deficiency in China. Seventeen of the 25 patie...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1789514
更新日期:2020-06-09 00:00:00
abstract:Background:Long noncoding RNAs (lncRNAs) play a crucial role in varieties of biological processes. This study is aimed at investigating meniscal degeneration-specific lncRNAs and mRNAs and their related networks in knee osteoarthritis (KOA). Methods:The dataset GSE98918, which included 24 meniscus samples and related ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2123787
更新日期:2020-05-20 00:00:00
abstract:Background:Fingertips are a common site for hand injuries. The ideal substitute for fingertip pulp is tissue that matches texturally with minimal donor site morbidity. We described anatomical findings from cadaveric studies and the reliability of the palmar ulnar artery perforator (PUAP) free flap techniques for the re...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/2862879
更新日期:2018-05-09 00:00:00
abstract:Background:Diabetes mellitus (DM) is a common disease that has an adverse impact on most orthopedic surgeries, and its prevalence has gradually increased in recent years. We aim to investigate the influence of DM on comorbidities and complications of patients undergoing primary total lower extremity arthroplasty. Meth...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/6661691
更新日期:2020-12-15 00:00:00