Association of Ki-67 Labelling Index and IL-17A with Pituitary Adenoma.

abstract：:The research was performed on male Wistar rats based on assumptions that new microelement preparations containing metal nanoparticles and their agglomerates had potential. Morphological and functional changes in tissues in the injection site and dynamics of chemical element metabolism (25 indicators) in body were asse...

journal_title：BioMed research international

authors： Sizova E,Miroshnikov S,Yausheva E,Polyakova V

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Tuberculosis is still one of the most important health problems in developing countries and increasing drug resistance is the main concern for its treatment. This study was designed to characterize the drug resistant Mycobacterium tuberculosis isolated from patients suffering from pulmonary tuberculosis in...

journal_title：BioMed research international

authors： Tavanaee Sani A,Shakiba A,Salehi M,Bahrami Taghanaki HR,Ayati Fard SF,Ghazvini K

更新日期：2015-01-01 00:00:00

abstract：:The present study was proposed to investigate the toxicological and prophylactic potential of ethanolic extracts of Rosa damascena and Nymphaea alba and their mixture in albino mice. For toxicity study, three different doses of plant extracts were orally administrated to three groups of mice for 14 successive days. Bl...

journal_title：BioMed research international

authors： Batool R,Kalsoom A,Akbar I,Arshad N,Jamil N

更新日期：2018-01-23 00:00:00

abstract：:Amylase is an industrially important enzyme and applied in many industrial processes such as saccharification of starchy materials, food, pharmaceutical, detergent, and textile industries. This research work deals with the optimization of fermentation conditions for α-amylase production from thermophilic bacterial str...

journal_title：BioMed research international

authors： Simair AA,Qureshi AS,Khushk I,Ali CH,Lashari S,Bhutto MA,Mangrio GS,Lu C

更新日期：2017-01-01 00:00:00

abstract：:Actin is one of the most highly conserved proteins and plays crucial roles in many vital cellular functions. In most eukaryotes, it is encoded by a multigene family. Although the actin gene family has been studied a lot, few investigators focus on the comparison of actin gene family in relative species. Here, the purp...

journal_title：BioMed research international

authors： Zhu L,Zhang Y,Hu Y,Wen T,Wang Q

更新日期：2013-01-01 00:00:00

abstract：:There were no systematic researches about autophagy-related long noncoding RNA (lncRNA) signatures to predict the survival of patients with colon adenocarcinoma. It was necessary to set up corresponding autophagy-related lncRNA signatures. The expression profiles of lncRNAs which contained 480 colon adenocarcinoma sam...

journal_title：BioMed research international

authors： Zhou W,Zhang S,Li HB,Cai Z,Tang S,Chen LX,Lang JY,Chen Z,Chen XL

更新日期：2020-09-02 00:00:00

abstract：:Guanosine is an important building block for supramolecular gels owing to the unique self-assembly property that results from the unique hydrogen bond acceptors and donor groups. Guanosine-derived supramolecular hydrogels have promise in the fields of drug delivery, targeted release, tissue engineering applications, e...

journal_title：BioMed research international

authors： Chen M,Lin W,Hong L,Ji N,Zhao H

更新日期：2019-06-13 00:00:00

abstract：:Objectives. This study aimed to determine the feasibility of cochlear implantation for sensorineural hearing loss in patients with Waardenburg syndrome. Method. A retrospective chart review was performed on patients who underwent cochlear implantation at the University of Tokyo Hospital. Clinical classification, genet...

journal_title：BioMed research international

authors： Koyama H,Kashio A,Sakata A,Tsutsumiuchi K,Matsumoto Y,Karino S,Kakigi A,Iwasaki S,Yamasoba T

更新日期：2016-01-01 00:00:00

abstract：:The Janus Kinases (JAKs) are a family of intracellular tyrosine kinases that provide transmission signals from cytokine, interferons, and many hormones receptors to the nucleus resulting in synthesis of many biologically active compounds and changing cell metabolism and function. That was theoretical background to syn...

journal_title：BioMed research international

authors： Kotyla PJ

更新日期：2018-05-10 00:00:00

abstract：:The availability of an active substance through the skin depends basically on two consecutive steps: the release of this substance from the vehicle and its subsequent permeation through the skin. Hence, studies on the specific properties of vehicles, such as their rheological behavior, are of great interest in the fie...

journal_title：BioMed research international

authors： Isaac VL,Chiari-Andréo BG,Marto JM,Moraes JD,Leone BA,Corrêa MA,Ribeiro HM

更新日期：2015-01-01 00:00:00

abstract：:Arthritogenic alphaviruses, including Ross River virus (RRV), Chikungunya virus (CHIKV), Sindbis virus (SINV), Mayaro virus (MAYV), O'nyong-nyong virus (ONNV), and Barmah Forest virus (BFV), cause incapacitating and long lasting articular disease/myalgia. Outbreaks of viral arthritis and the global distribution of the...

journal_title：BioMed research international

authors： Assunção-Miranda I,Cruz-Oliveira C,Da Poian AT

更新日期：2013-01-01 00:00:00

abstract：:Fluconazole is a broad-spectrum triazole antifungal that is well-established as the first-line treatment for Candida albicans infections. Despite its extensive use, reports on its genotoxic/mutagenic effects are controversial; therefore, further studies are needed to better clarify such effects. African green monkey k...

journal_title：BioMed research international

authors： Correa RMDS,Mota TC,Guimarães AC,Bonfim LT,Burbano RR,Bahia MO

更新日期：2018-11-01 00:00:00

abstract：:Escherichia coli O157:H7 is the main causative agent of haemolytic uremic syndrome. Cattle are the main reservoir of these bacteria, and have been shown to develop immune response to colonization. Our aim was to investigate the faecal shedding pattern of E. coli O157:H7 in calves challenged intragastrically with eithe...

journal_title：BioMed research international

authors： Martorelli L,Hovde CJ,Vilte DA,Albanese A,Zotta E,Ibarra C,Cantet RJ,Mercado EC,Cataldi A

更新日期：2015-01-01 00:00:00

abstract：:Antipsychotic drugs (APDs) used to treat clinical psychotic syndromes cause a variety of blood dyscrasias. APDs suppress the aggregation of platelets; however, the underlying mechanism remains unknown. We first analyzed platelet aggregation and clot formation in platelets treated with APDs, risperidone, clozapine, or ...

journal_title：BioMed research international

authors： Wu CC,Tsai FM,Chen ML,Wu S,Lee MC,Tsai TC,Wang LK,Wang CH

更新日期：2016-01-01 00:00:00

abstract：:Aim. In periodontology lasers have been suggested for the photodynamic therapy (PDT): such therapy can be defined as the inactivation of cells, microorganisms, or molecules induced by light and not by heat. The aim of this study was to evaluate results of PDT using a 980 nm diode laser (Wiser Doctor Smile, Lambda SPA,...

journal_title：BioMed research international

authors： Caccianiga G,Baldoni M,Ghisalberti CA,Paiusco A

更新日期：2016-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) accounts for a significant proportion of liver cancer, which has become the second most common cause of cancer-related mortality worldwide. To investigate the potential mechanisms of invasion and progression of HCC, bioinformatics analysis and validation by qRT-PCR were performed. We fou...

journal_title：BioMed research international

authors： Liu S,Yao X,Zhang D,Sheng J,Wen X,Wang Q,Chen G,Li Z,Du Z,Zhang X

更新日期：2018-08-29 00:00:00

abstract：:Although the application of patient-specific instruments (PSI) for total knee arthroplasty (TKA) increases the cost of the surgical procedure, PSI may reduce operative time and improve implant alignment, which could reduce the number of revision surgeries. We report our experience with TKA using PSI techniques in 120 ...

journal_title：BioMed research international

authors： Kwon OR,Kang KT,Son J,Choi YJ,Suh DS,Koh YG

更新日期：2015-01-01 00:00:00

abstract：Background/Aims:The molecular mechanism of dormancy initiation of cancer stem cells (CSCs) is not clear. This study was to explore the molecular mechanism by which CSCs switch from mitotic division to quiescence. Methods:MTT assays, flow cytometry, Western blotting, qRT-PCR, and immunofluorescence staining were used t...

journal_title：BioMed research international

authors： Zhang W,Ren Z,Jia L,Li X,Jia X,Han Y

更新日期：2019-08-25 00:00:00

abstract：:Sulfated polysaccharides (GSP) were isolated from the cloned Grateloupia filicina which was cultured in Jiaozhou Bay, Qingdao, China. The yield of GSP was 15.75%. The total sugar and sulfate were 40.90 and 19.89%, respectively. And the average molecular weight was 11.7 KDa. The results of neutral sugar analysis showed...

journal_title：BioMed research international

authors： Chen X,Yang S,Wang J,Song L,Xing R,Liu S,Yu H,Li P

更新日期：2015-01-01 00:00:00

abstract：:Uterine fibroids (UFs) are benign tumors of the reproductive tract, arising from smooth muscle cells of the uterus. Steroid hormones, estrogen, and progesterone are considered to be the most important links in the pathophysiology of UFs. Alpha-tocopherol (AT) is the most active form of vitamin E. What is important as ...

journal_title：BioMed research international

authors： Ciebiera M,Szymańska-Majchrzak J,Sentkowska A,Kilian K,Rogulski Z,Nowicka G,Jakiel G,Tomaszewski P,Włodarczyk M

更新日期：2018-07-24 00:00:00

abstract：:This study was aimed to evaluate the in vitro lethal activity of the nematophagous fungi Clonostachys rosea against 5 nematodes species belonging to different taxa. Two groups of 35 Petri dishes (PD) each were divided into 5 series of 7 (PD). Group 1 (series 1, 2, 3, 4, and 5) contained only water agar; meanwhile grou...

journal_title：BioMed research international

authors： Rodríguez-Martínez R,Mendoza-de-Gives P,Aguilar-Marcelino L,López-Arellano ME,Gamboa-Angulo M,Hanako Rosas-Saito G,Reyes-Estébanez M,Guadalupe García-Rubio V

更新日期：2018-03-20 00:00:00

abstract：Purpose:β-Defensin 118 (DEFB118) is a novel host defense peptide (HDP) identified in humans. To evaluate its potentials for future utilization, the DEFB118 gene was expressed in Escherichia coli (E. coli) and the recombinant protein was fully characterized. Methods:The DEFB118 protein was obtained by heterologous expr...

journal_title：BioMed research international

authors： Lin Q,Xie K,Chen D,Yu B,Mao X,Yu J,Luo J,Zheng P,Luo Y,Yan H,He J

更新日期：2020-11-09 00:00:00

abstract：:Due to expanding applications of positron emission tomography (PET) there is a demand for developing new techniques to introduce fluorine-18 (t 1/2 = 109.8 min). Considering that most novel PET tracers are sensitive biomolecules and that direct introduction of fluorine-18 often needs harsh conditions, the insertion of...

journal_title：BioMed research international

authors： Kettenbach K,Schieferstein H,Ross TL

更新日期：2014-01-01 00:00:00

abstract：:Stem cells have been proposed as a promising therapy for treating stroke. While several studies have demonstrated the therapeutic benefits of stem cells, the exact mechanism remains elusive. Molecular imaging provides the possibility of the visual representation of biological processes at the cellular and molecular le...

journal_title：BioMed research international

authors： Chao F,Shen Y,Zhang H,Tian M

更新日期：2013-01-01 00:00:00

abstract：:Introduction. Given its efficacy and safety, NexoBrid™ (NXB) has become part of our therapeutic options in burns treatment with satisfactory results. However, no cost analysis comparing NXB to the standard of care (SOC) has been carried out as of today. Aim. To assess the cost of treatment with NXB and compare it to t...

journal_title：BioMed research international

authors： Giudice G,Filoni A,Maggio G,Bonamonte D,Vestita M

更新日期：2017-01-01 00:00:00

abstract：:SARS-CoV-2 pandemic and COVID-19 diffusion have recently become an international public health emergency. Cancer patients, as a frail population, are particularly exposed to the risk related to infections. The clinical decision-making process and the organizational workflow of radiotherapy department should be revised...

journal_title：BioMed research international

authors： Franco P,Kochbati L,Siano M,De Bari B

更新日期：2020-05-26 00:00:00

abstract：OBJECTIVE:In the process of care for disorders of sex development (DSD), clinical decisions should focus on the long-term quality of life (QOL). We sought to investigate the QOL of patients with DSD in China. DESIGN:Case-control study was carried out. PATIENTS:90 patients of DSD participated in the study. Finally, 87...

journal_title：BioMed research international

authors： Wang C,Tian Q

更新日期：2015-01-01 00:00:00

abstract：:Substitution rates strongly depend on their nucleotide context. One of the most studied examples is the excess of C > T mutations in the CG context in various groups of organisms, including vertebrates. Studies on the molecular mechanisms underlying this mutation regularity have provided insights into evolution, mutag...

journal_title：BioMed research international

authors： Medvedeva SA,Panchin AY,Alexeevski AV,Spirin SA,Panchin YV

更新日期：2013-01-01 00:00:00

abstract：:This 12-week clinical study evaluated the impact of 10% CPP-ACP and 5% sodium fluoride varnish regimes on the regression of nonorthodontic white spot lesions (WSLs). The study included 21 children with 101 WSLs who were randomised into four treatment regimes: weekly clinical applications of fluoride varnish for the fi...

journal_title：BioMed research international

authors： Güçlü ZA,Alaçam A,Coleman NJ

更新日期：2016-01-01 00:00:00

abstract：Background:The use of modern family planning methods among women of reproductive age (15-49 years) is of public health importance in Ethiopia. Nationally, modern family planning method use remains as low as 35%. Understanding factors associated with the use of modern family planning methods may help to improve maternal...

journal_title：BioMed research international

authors： Mulatu T,Sintayehu Y,Dessie Y,Deressa M

更新日期：2020-12-29 00:00:00