Sulfated Polysaccharides Isolated from Cloned Grateloupia filicina and Their Anticoagulant Activity.

Abstract:

:Sulfated polysaccharides (GSP) were isolated from the cloned Grateloupia filicina which was cultured in Jiaozhou Bay, Qingdao, China. The yield of GSP was 15.75%. The total sugar and sulfate were 40.90 and 19.89%, respectively. And the average molecular weight was 11.7 KDa. The results of neutral sugar analysis showed that GSP was mainly sulfated polysaccharides of galactose. The experiments for activated partial thromboplastin time (APTT), prothrombin time (PT), and thrombin time (TT) anticoagulant assays in vitro indicated that GSP was a good potential anticoagulant. Therefore, this study supplied new thought for the cloned Grateloupia filicina exploitation of high-value products.

journal_name

Biomed Res Int

authors

Chen X,Yang S,Wang J,Song L,Xing R,Liu S,Yu H,Li P

doi

10.1155/2015/612352

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

612352

eissn

2314-6133

issn

2314-6141

journal_volume

2015

pub_type

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