The Development and Lifetime Stability Improvement of Guanosine-Based Supramolecular Hydrogels through Optimized Structure.

abstract：:ADP-glucose pyrophosphorylase (AGPase) is the first rate limiting enzyme of starch biosynthesis pathway and has been exploited as the target for greater starch yield in several plants. The structure-function analysis and substrate binding specificity of AGPase have provided enormous potential for understanding the rol...

journal_title：BioMed research international

authors： Sarma K,Sen P,Barooah M,Choudhury MD,Roychoudhury S,Modi MK

更新日期：2014-01-01 00:00:00

abstract：:Diabetes-triggered apoptosis of Schwann cells (SC) contributes to the degradation of diabetic peripheral neuropathy (DNP). In recent years, mesenchymal stem cells (MSC) were applied to DPN repair and it was demonstrated that paracrine secretion played a key role in neuroprotection exerted by MSC. Erythropoietin (EPO) ...

journal_title：BioMed research international

authors： Zhang S,Shi B

更新日期：2017-01-01 00:00:00

abstract：:Molecular recognition elements (MREs) can be short sequences of single-stranded DNA, RNA, small peptides, or antibody fragments. They can bind to user-defined targets with high affinity and specificity. There has been an increasing interest in the identification and application of nucleic acid molecular recognition el...

journal_title：BioMed research international

authors： Hong KL,Sooter LJ

更新日期：2015-01-01 00:00:00

abstract：:Blocking glioma cell invasion has been challenging due to cancer cells that can swiftly switch their migration mode, and agents that can block more than one migration mode are sought after. We found that small molecule 2-(1H-indole-3-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE), an endogenous aryl hydrocarb...

journal_title：BioMed research international

authors： Zhao L,Shu Q,Sun H,Ma Y,Kang D,Zhao Y,Lu J,Gong P,Yang F,Wan F

更新日期：2020-10-03 00:00:00

abstract：:In patients with sepsis and septic shock, the hemodynamic management in both early and later phases of these "organ dysfunction syndromes" is a key therapeutic component. It needs, however, to be differentiated between "early goal-directed therapy" (EGDT) as proposed for the first 6 hours of emergency department treat...

journal_title：BioMed research international

authors： Saugel B,Huber W,Nierhaus A,Kluge S,Reuter DA,Wagner JY

更新日期：2016-01-01 00:00:00

abstract：:Background. Genome-wide association studies (GWAS) have shown its revolutionary power in seeking the influenced loci on complex diseases genetically. Thousands of replicated loci for common traits are helpful in diseases risk assessment. However it is still difficult to elucidate the variations in these loci that dire...

journal_title：BioMed research international

authors： Ma LX,Wang YJ,Wang JF,Li X,Hao P

更新日期：2013-01-01 00:00:00

abstract：:DNA Primase Subunit 1 (PRIM1) is crucial for cancer development and progression. However, there remains a lack of comprehension concerning the clinical implication of PRIM1 in HCC. Here, aberrant expression of PRIM1 was identified in HCC according to available databases. The prognostic value of PRIM1 in patients prese...

journal_title：BioMed research international

authors： Zhang Y,Li L,Liu R,Zeng C

更新日期：2020-08-22 00:00:00

abstract：:Angiogenesis is essential for tumor growth and metastasis. Over the last decades, a substantial progress has been achieved in defining different patterns of tumor microcirculation. Sprouting angiogenesis, the oldest model of microcirculation, is the de novo vessel formation from preexisting blood vessels. Vessel split...

journal_title：BioMed research international

authors： Alameddine RS,Hamieh L,Shamseddine A

更新日期：2014-01-01 00:00:00

abstract：:It has been reported that diabetes mellitus (DM) was an epidemiologically identified risk factor for development of dengue hemorrhagic fever (DHF)/severe dengue in dengue virus (DENV) affected patients, and T helper 2 (Th2) cytokines such as interleukin-4 (IL-4) and IL-10 each plays an important role in the immunopath...

journal_title：BioMed research international

authors： Lee IK,Hsieh CJ,Chen RF,Yang ZS,Wang L,Chen CM,Liu CF,Huang CH,Lin CY,Chen YH,Yang KD,Liu JW

更新日期：2013-01-01 00:00:00

abstract：:A Chinese medicinal fern Blechnum orientale (Linn) was separately collected from polluted and unpolluted sites to determine whether it could accumulate hazardous pollutants or not. Metal concentrations (Cu, Zn, Mn, Pb, Cd, Cr, As, and Hg) both in the fronds and roots and polycyclic aromatic hydrocarbons (PAHs) in the ...

journal_title：BioMed research international

authors： Zhu XM,Kuang YW,Xi D,Li J,Wang FG

更新日期：2013-01-01 00:00:00

abstract：Background:This study investigates the differences in the lateral profile and frontal appearance after sagittal split ramus osteotomy (SSRO) and intraoral vertical ramus osteotomy (IVRO) procedures for the correction of mandibular prognathism. Methods:Sixty patients (30 SSRO and 30 IVRO) underwent mandibular setback s...

journal_title：BioMed research international

authors： Chen CM,Tseng YC,Ko EC,Chen MY,Chen KJ,Cheng JH

更新日期：2018-12-18 00:00:00

abstract：:Pinelliae Rhizoma Praeparatum Cum Alumine (PRPCA) is useful for eliminating dampness and phlegm in clinical settings, targeting the main mechanisms of insomnia as defined in traditional Chinese medicine. However, little is known regarding the sedative and hypnotic effects of PRPCA. In the present study, we examined th...

journal_title：BioMed research international

authors： Lin S,Nie B,Song K,Ye R,Yuan Z

更新日期：2019-04-28 00:00:00

abstract：:Following cerebral ischemia/reperfusion (I/R) injury, a series of pathophysiological processes are stimulated in both the central nervous system (CNS) and the periphery, including, but not limited to, the peripheral immune and endocrine systems and underregulation of the neuroendocrine-immune network. Glutamate (Glu) ...

journal_title：BioMed research international

authors： You J,Feng L,Xin M,Ma D,Feng J

更新日期：2018-07-19 00:00:00

abstract：:Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen...

journal_title：BioMed research international

authors： Wu J,Xia S,Kalionis B,Wan W,Sun T

更新日期：2014-01-01 00:00:00

abstract：:In this study dairy sludge was evaluated as an alternative cultivation medium for Rhizobium. Growth of bacterial strains at different concentrations of Dairy sludge was monitored. Maximum growth of all strains was observed at 60% Dairy sludge concentration. At 60% optical density (OD) values are 0.804 for Rhizobium tr...

journal_title：BioMed research international

authors： Singh AK,Singh G,Gautam D,Bedi MK

更新日期：2013-01-01 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：:It is increasingly affirmed that most of the long-term consequences of TBI are due to molecular and cellular changes occurring during the acute phase of the injury and which may, afterwards, persist or progress. Understanding how to prevent secondary damage and improve outcome in trauma patients, has been always a tar...

journal_title：BioMed research international

authors： Mangiola A,Vigo V,Anile C,De Bonis P,Marziali G,Lofrese G

更新日期：2015-01-01 00:00:00

abstract：:Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin induces EMT and acts...

journal_title：BioMed research international

authors： Rodrigues-Diez R,Rodrigues-Diez RR,Lavoz C,Carvajal G,Droguett A,Garcia-Redondo AB,Rodriguez I,Ortiz A,Egido J,Mezzano S,Ruiz-Ortega M

更新日期：2014-01-01 00:00:00

abstract：Objectives:This study aims to determine the changing in hip anatomy parameters with age and reveals the reason for the extorsion of lower extremity in the aged. Design:Retrospective study. Participants:One hundred and forty patients who had received imaging check of the femur and acetabulum between October 2013 and O...

journal_title：BioMed research international

authors： Yin Y,Zhang R,Jin L,Li S,Hou Z,Zhang Y

更新日期：2018-09-27 00:00:00

abstract：:Aldosterone synthase (CYP11B2) is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS) and lead to hypertension. Therefore, research and development of CYP...

journal_title：BioMed research international

authors： Luo G,Lu F,Qiao L,Chen X,Li G,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:The aim of the present study was to evaluate the antitumor potential of iminoflavones in in vitro and in vivo anticancer models. Preliminary screening in various cancer cell lines revealed four potential iminoflavones out of which IMF-8 was taken based on its activity against colon cancer cells. This was further confi...

journal_title：BioMed research international

authors： Prasad VG,Kawade S,Jayashree BS,Reddy ND,Francis A,Nayak PG,Kishore A,Nandakumar K,Rao CM,Shenoy RR

更新日期：2014-01-01 00:00:00

abstract：:Tyrosine kinase inhibitors (TKI) belong to a new class of molecular multitargeted anticancer therapy which targets different growth factor receptors and hence attenuates cancer cell survival and growth. Since their introduction as adjunct treatment for renal cell carcinoma and gastrointestinal stromal tumors (GIST), a...

journal_title：BioMed research international

authors： Ahmadieh H,Salti I

更新日期：2013-01-01 00:00:00

abstract：:Introduction. The aim of the present study was to determine the closeness of agreement between a self-reported and an objective measure of physical activity in low back pain patients and healthy controls. Beyond, influencing factors on overestimation were identified. Methods. 27 low back pain patients and 53 healthy c...

journal_title：BioMed research international

authors： Schaller A,Rudolf K,Dejonghe L,Grieben C,Froboese I

更新日期：2016-01-01 00:00:00

abstract：:A standard protocol of dosimetric measurements is used by the organizations responsible for verifying that the doses delivered in radiation-therapy institutions are within authorized limits. This study evaluated a self-designed simple auditing phantom for use in verifying the dose of radiation therapy; the phantom des...

journal_title：BioMed research international

authors： Lee JH,Chang LT,Shiau AC,Chen CW,Liao YJ,Li WJ,Lee MS,Hsu SM

更新日期：2015-01-01 00:00:00

abstract：:Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...

journal_title：BioMed research international

authors： Tan BL,Norhaizan ME

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:The use of unlicensed food and herbal supplements to enhance sexual functions is drastically increasing. This phenomenon, combined with the availability of these products over the Internet, represents a challenge from a clinical and a public health perspective. METHODS:A comprehensive multilingual assessm...

journal_title：BioMed research international

authors： Corazza O,Martinotti G,Santacroce R,Chillemi E,Di Giannantonio M,Schifano F,Cellek S

更新日期：2014-01-01 00:00:00

abstract：:The sphingosine-1-phosphate (S1P) system regulates both thymic and lymph nodes T cell egress which is essential for producing and maintaining the recycling T cell repertoire. Infection with the protozoan parasite Trypanosoma cruzi induces a hormonal systemic deregulation that has impact in the thymic S1P homeostasis t...

journal_title：BioMed research international

authors： Flávia Nardy A,Santos L,Freire-de-Lima CG,Morrot A

更新日期：2015-01-01 00:00:00

abstract：:Gender affirmation surgery remains one of the greatest challenges in transgender medicine. In recent years, there have been continuous discussions on bioethical aspects in the treatment of persons with gender dysphoria. Gender reassignment is a difficult process, including not only hormonal treatment with possible sur...

journal_title：BioMed research international

authors： Bizic MR,Jeftovic M,Pusica S,Stojanovic B,Duisin D,Vujovic S,Rakic V,Djordjevic ML

更新日期：2018-06-13 00:00:00

abstract：OBJECT:The aim of this report was to explore the clinical presentation, radiological features, treatment methods, and outcome of micro-AVMs presenting with intracerebral hemorrhage. METHODS:The clinical data, radiological features, treatment, and follow-up results for a consecutive series of 13 cases with micro-AVMs w...

journal_title：BioMed research international

authors： Hong JF,Song YF,Liu HB,Liu Z,Wang SS

更新日期：2015-01-01 00:00:00

abstract：:In continuance of our search for anticancer agents, we report herein the synthesis and anticancer activity of some novel oxadiazole analogues. The compounds were screened for anticancer activity as per National Cancer Institute (NCI US) protocol on leukemia, melanoma, lung, colon, CNS, ovarian, renal, prostate, and br...

journal_title：BioMed research international

authors： Ahsan MJ,Sharma J,Singh M,Jadav SS,Yasmin S

更新日期：2014-01-01 00:00:00