Gender Dysphoria: Bioethical Aspects of Medical Treatment.

abstract：:Recent studies suggest that nucleotide-binding domain leucine-rich repeat protein 1 (NLRP1) is a pivotal factor in the inflammatory process. However, the role of NLRP1 in breast cancer pathogenesis remains unclear. The aim of this study was to examine the expression and function of NLRP1 in breast cancer. We found tha...

journal_title：BioMed research international

authors： Wei Y,Huang H,Qiu Z,Li H,Tan J,Ren G,Wang X

更新日期：2017-01-01 00:00:00

abstract：:For more than 30 years, heart transplantation has been a successful therapy for patients with terminal heart failure. Mechanical circulatory support (MCS) was developed as a therapy for end-stage heart failure at a time when cardiac transplantation was not yet a useful treatment modality. With the more successful outc...

journal_title：BioMed research international

authors： Anand J,Singh SK,Antoun DG,Cohn WE,Frazier OH,Mallidi HR

更新日期：2015-01-01 00:00:00

abstract：AIMS/INTRODUCTION:Determining the prevalence of diabetes and its cardiovascular complications and all-cause mortality in older chronic complex patients. MATERIALS AND METHODS:We carried out a multicenter retrospective study and included a randomized sample of 932 CCP people. We assessed the prevalence of diabetes acco...

journal_title：BioMed research international

authors： Clua-Espuny JL,González-Henares MA,Queralt-Tomas MLL,Campo-Tamayo W,Muria-Subirats E,Panisello-Tafalla A,Lucas-Noll J

更新日期：2017-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/8094152.]. ...

journal_title：BioMed research international

authors： Xie Y,Su Y,Min S,Tang J,Goh BT,Saigo L,Ansari S,Moshaverinia A,Zhang C,Wang J,Liu Y,Khojasteh A,Zadeh HH,Wang S

更新日期：2017-01-01 00:00:00

abstract：:Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC pr...

journal_title：BioMed research international

authors： Lahner M,Ull C,Hagen M,von Schulze Pellengahr C,Daniilidis K,von Engelhardt LV,Lahner N,Teske W

更新日期：2018-05-08 00:00:00

abstract：:Information and communications technology (ICT) could support ambient assisted living (AAL) based interventions to provide support to informal caregivers of people with dementia, especially when they need to cope with their feelings of overburden or isolation. An e-learning platform (understAID application) was tested...

journal_title：BioMed research international

authors： Núñez-Naveira L,Alonso-Búa B,de Labra C,Gregersen R,Maibom K,Mojs E,Krawczyk-Wasielewska A,Millán-Calenti JC

更新日期：2016-01-01 00:00:00

abstract：:The hepatoprotective and antioxidant activity of Bauhinia hookeri ethanol extract (BHE) against CCl4-induced liver injury was investigated in mice. BHE was administered (500 and 1000 mg/kg/day) along with CCl4 for 6 weeks. The hepatic marker enzymes: alanine aminotransferase (ALT), aspartate aminotransferase (AST), an...

journal_title：BioMed research international

authors： Al-Sayed E,Martiskainen O,Seif el-Din SH,Sabra AN,Hammam OA,El-Lakkany NM,Abdel-Daim MM

更新日期：2014-01-01 00:00:00

abstract：:Vocal tract morphology is an important factor in voice production. Its analysis has potential implications for educational matters as well as medical issues like voice therapy. The knowledge of the complex adjustments in the spatial geometry of the vocal tract during phonation is still limited. For a major part, this ...

journal_title：BioMed research international

authors： Poznyakovskiy AA,Mainka A,Platzek I,Mürbe D

更新日期：2015-01-01 00:00:00

abstract：:Lung illness encountered in patients with rheumatic diseases bears clinical significance in terms of increased morbidity and mortality as well as potential challenges placed on patient care. Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accum...

journal_title：BioMed research international

authors： Ha YJ,Lee YJ,Kang EH

更新日期：2018-05-08 00:00:00

abstract：:Despite the rapid progression of cancer pharmacotherapy, the high drug resistance of pancreatic ductal adenocarcinoma (PDA) makes it one of the most lethal malignancies. Therefore, there are high expectations associated with experimental therapies, such as electrochemotherapy (ECT). This technique involves the applica...

journal_title：BioMed research international

authors： Michel O,Kulbacka J,Saczko J,Mączyńska J,Błasiak P,Rossowska J,Rzechonek A

更新日期：2018-03-19 00:00:00

abstract：Objectives:Magnetic resonance imaging (MRI) and in particular diffusion-weighted imaging (DWI) have been broadly proven to be the reference imaging method to discriminate between cholesteatoma and noncholesteatomatous middle ear lesions, especially when high tissue specificity is required. The aim of this study is to d...

journal_title：BioMed research international

authors： Russo C,Elefante A,Di Lullo AM,Carotenuto B,D'Amico A,Cavaliere M,Iengo M,Brunetti A

更新日期：2018-04-24 00:00:00

abstract：:Epithelial Cl(-) secretion plays important roles in water secretion preventing bacterial/viral infection and regulation of body fluid. We previously suggested that quercetin would be a useful compound for maintaining epithelial Cl(-) secretion at a moderate level irrespective of cAMP-induced stimulation. However, we n...

journal_title：BioMed research international

authors： Sun H,Niisato N,Nishio K,Hamilton KL,Marunaka Y

更新日期：2014-01-01 00:00:00

abstract：Objective:Biomaterial research for soft tissue augmentation is an increasing topic in aesthetic medicine. Hyaluronic acid (HA) fillers are widely used for their low invasiveness and easy application to correct aesthetic defects or traumatic injuries. Some complications as acute or chronic inflammation can occur in pati...

journal_title：BioMed research international

authors： Cannella V,Altomare R,Leonardi V,Russotto L,Di Bella S,Mira F,Guercio A

更新日期：2020-05-21 00:00:00

abstract：:Background. Surgical treatment of proximal humeral fractures (PHF) in osteoporotic bone of elderly patients is challenging. The aim of this retrospective study was to evaluate the clinical and radiological outcome after percutaneous reduction and internal fixation of osteoporotic PHF in geriatric patients using the se...

journal_title：BioMed research international

authors： Bogner R,Ortmaier R,Moroder P,Karpik S,Wutte C,Lederer S,Auffarth A,Resch H

更新日期：2016-01-01 00:00:00

abstract：:Contamination of heavy metals would threaten the water and soil resources; phytoremediation can be potentially used to remediate metal contaminated sites. We constructed the Phragmites australis artificial floating wetlands outside the Qingcaosha Reservoir in the Yangtze Estuary. Water characteristic variables were me...

journal_title：BioMed research international

authors： Huang X,Zhao F,Yu G,Song C,Geng Z,Zhuang P

更新日期：2017-01-01 00:00:00

abstract：:Cancer treatment is undergoing a significant revolution from "one-size-fits-all" cytotoxic therapies to tailored approaches that precisely target molecular alterations. Precision strategies for drug development and patient stratification, based on the molecular features of tumors, are the next logical step in a long h...

journal_title：BioMed research international

authors： Coyle KM,Boudreau JE,Marcato P

更新日期：2017-01-01 00:00:00

abstract：:This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The interventi...

journal_title：BioMed research international

authors： Moss J,Tew GA,Copeland RJ,Stout M,Billings CG,Saxton JM,Winter EM,Bianchi SM

更新日期：2014-01-01 00:00:00

abstract：:A diffusion theory-based, all-physical ab initio protein folding simulation is described and applied. The model is based upon the drift and diffusion of protein substructures relative to one another in the multiple energy fields present. Without templates or statistical inputs, the simulations were run at physiologic ...

journal_title：BioMed research international

authors： Kang Y,Fortmann CM

更新日期：2013-01-01 00:00:00

abstract：:The aim of the study was to assess the prevalence of temporomandibular disorders (TMD) and oral parafunctions, as well as their correlation with psychoemotional factors in Polish university students. The research was conducted in a group of 456 students (N = 456). The examination form comprised of two parts: survey an...

journal_title：BioMed research international

authors： Wieckiewicz M,Grychowska N,Wojciechowski K,Pelc A,Augustyniak M,Sleboda A,Zietek M

更新日期：2014-01-01 00:00:00

abstract：:Our aim was to verify the effects of prednisone related to gastrointestinal motility, intestinal histology, and mucosal mast cells in rats. Two-month-old male Wistar rats were randomly assigned to control group (vehicle) animals receiving saline 0.9% (n = 7) or treated orally with 0.625 mg/kg/day of prednisone (n = 7)...

journal_title：BioMed research international

authors： de Lima MB,Gama LA,Hauschildt AT,Dall'Agnol DJR,Corá LA,Americo MF

更新日期：2017-01-01 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) is one of the most common cancers in the world. Our aim is to identify prognostic biomarkers that contribute to the progression of early stage ccRCC and clarify the mechanism. Here, the mRNA microarray expression profile of ccRCC samples was obtained from Gene Expression Omnibus...

journal_title：BioMed research international

authors： Qiu X,Gu Y,Ni Y,Li Q

更新日期：2020-10-29 00:00:00

abstract：:Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular process that degrades damaged o...

journal_title：BioMed research international

authors： Song Y,Zhao Y,Wang F,Tao L,Xiao J,Yang C

更新日期：2014-01-01 00:00:00

abstract：:Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs are bound to conforma...

journal_title：BioMed research international

authors： Hu WG,Yin J,Chau D,Hu CC,Lillico D,Yu J,Negrych LM,Cherwonogrodzky JW

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-HT2B receptor antagon...

journal_title：BioMed research international

authors： Janssen W,Schymura Y,Novoyatleva T,Kojonazarov B,Boehm M,Wietelmann A,Luitel H,Murmann K,Krompiec DR,Tretyn A,Pullamsetti SS,Weissmann N,Seeger W,Ghofrani HA,Schermuly RT

更新日期：2015-01-01 00:00:00

abstract：:This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of bl...

journal_title：BioMed research international

authors： Zhang Q,Zhang Y,Zhou Y,Zhang K,Zhang K,Gao L

更新日期：2016-01-01 00:00:00

abstract：:Abdominal pregnancy is a very rare form of ectopic pregnancy, associated with high morbidity and mortality for both fetus and mother. It is, and often, seen in poor resource nations, where early diagnosis is often a major challenge due to poor prenatal care and lack of medical resources. An advanced abdominal pregnanc...

journal_title：BioMed research international

authors： Dabiri T,Marroquin GA,Bendek B,Agamasu E,Mikhail M

更新日期：2014-01-01 00:00:00

abstract：:Canine mammary gland tumor (CMT) is the most common tumor in intact female dog. Zerumbone (ZER) has promising anticancer properties, but plagued with poor water solubility, poor absorption, bioavailability, and delivery to target tissues. To solubilize, ZER was loaded into nanostructured lipid carrier (NLC) to produce...

journal_title：BioMed research international

authors： Foong JN,Selvarajah GT,Rasedee A,Rahman HS,How CW,Beh CY,Teo GY,Ku CL

更新日期：2018-10-15 00:00:00

abstract：:Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...

journal_title：BioMed research international

authors： Leem KH,Kim SA,Park HJ

更新日期：2020-10-17 00:00:00

abstract：:A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

journal_title：BioMed research international

authors： Rupachandra S,Sarada DV

更新日期：2014-01-01 00:00:00

abstract：:Chromosome rearrangements and fusion genes present major portion of leukemogenesis and contribute to leukemic subtypes. It is practical and helpful to detect the fusion genes in clinic diagnosis of leukemia. Present application of reverse transcription polymerase chain reaction (RT-PCR) method to detect the fusion gen...

journal_title：BioMed research international

authors： Xiong FF,Li BS,Zhang CX,Xiong H,Shen SH,Zhang QH

更新日期：2013-01-01 00:00:00