Minimally Invasive Treatment of Displaced Proximal Humeral Fractures in Patients Older Than 70 Years Using the Humerusblock.

abstract：:Finding an optimal set of discriminative features is still a crucial but challenging task in biomedical science. The complexity of the task is intensified when any of the two scenarios arise: a highly dimensioned dataset and a small sample-sized dataset. The first scenario poses a big challenge to existing machine lea...

journal_title：BioMed research international

authors： Segera D,Mbuthia M,Nyete A

更新日期：2020-08-17 00:00:00

abstract：:Music exposure is known to play a positive role in learning and memory and can be a complementary treatment for anxiety and fear. However, whether juvenile music exposure affects adult behavior is not known. Two-week-old Sprague-Dawley rats were exposed to music for 2 hours daily or to background noise (controls) for ...

journal_title：BioMed research international

authors： Chen S,Liang T,Zhou FH,Cao Y,Wang C,Wang FY,Li F,Zhou XF,Zhang JY,Li CQ

更新日期：2019-07-14 00:00:00

abstract：:There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...

journal_title：BioMed research international

authors： Paldino E,Tesori V,Casalbore P,Gasbarrini A,Puglisi MA

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Tuberculosis is still one of the most important health problems in developing countries and increasing drug resistance is the main concern for its treatment. This study was designed to characterize the drug resistant Mycobacterium tuberculosis isolated from patients suffering from pulmonary tuberculosis in...

journal_title：BioMed research international

authors： Tavanaee Sani A,Shakiba A,Salehi M,Bahrami Taghanaki HR,Ayati Fard SF,Ghazvini K

更新日期：2015-01-01 00:00:00

abstract：:Malaria is one of the life-threatening diseases in the world. The spread of resistance to antimalarial drugs is a major challenge, and resistance to artemisinin has been reported in the Southeast Asian region. In the previous study, the active compound of Streptomyces hygroscopicus subsp. Hygroscopicus (S. hygroscopic...

journal_title：BioMed research international

authors： Nugraha RY,Faratisha IF,Mardhiyyah K,Ariel DG,Putri FF,Nafisatuzzamrudah,Winarsih S,Sardjono TW,Fitri LE

更新日期：2020-01-09 00:00:00

abstract：:The study of the normal function and pathology of the inner ear has unique difficulties as it is inaccessible during life and, so, conventional techniques of pathologic studies such as biopsy and surgical excision are not feasible, without further impairing function. Mathematical modelling is therefore particularly at...

journal_title：BioMed research international

authors： Bellos C,Rigas G,Spiridon IF,Bibas A,Iliopoulou D,Böhnke F,Koutsouris D,Fotiadis DI

更新日期：2014-01-01 00:00:00

abstract：Background/Aims:The molecular mechanism of dormancy initiation of cancer stem cells (CSCs) is not clear. This study was to explore the molecular mechanism by which CSCs switch from mitotic division to quiescence. Methods:MTT assays, flow cytometry, Western blotting, qRT-PCR, and immunofluorescence staining were used t...

journal_title：BioMed research international

authors： Zhang W,Ren Z,Jia L,Li X,Jia X,Han Y

更新日期：2019-08-25 00:00:00

abstract：:Rheumatoid arthritis (RA) is a systemic multifactorial autoimmune disorder. The interactions between diverse environmental and genetic factors lead to the onset of this complex autoimmune disorder. Serum levels of vitamin D (VD) are involved in the regulation of various immune responses. Vitamin D is a key signaling m...

journal_title：BioMed research international

authors： Aslam MM,John P,Bhatti A,Jahangir S,Kamboh MI

更新日期：2019-05-07 00:00:00

abstract：:The knowledge on the genetic etiology of complex disorders largely results from the study of rare monogenic disorders. Often these common and rare diseases show phenotypic overlap, though monogenic diseases generally have a more extreme symptomatology. ABCC6, the gene responsible for pseudoxanthoma elasticum, an autos...

journal_title：BioMed research international

authors： De Vilder EY,Hosen MJ,Vanakker OM

更新日期：2015-01-01 00:00:00

abstract：Background:Osteonecrosis of the femoral head (ONFH) is a challenge for surgeons and is still without effective treatment method. This study is aimed at evaluating the combined pharmacotherapy with alendronate and desferoxamine for preventing glucocorticoid-induced osteonecrosis of the femoral head (GIOFH) and evaluatin...

journal_title：BioMed research international

authors： Sheng H,Lao Y,Zhang S,Ding W,Lu D,Xu B

更新日期：2020-09-21 00:00:00

abstract：:The prospect of biomaterial hypersensitivity developing in response to joint implant materials was first presented more than 30 years ago. Many studies have established probable causation between first-generation metal-on-metal hip implants and hypersensitivity reactions. In a limited patient population, implant failu...

journal_title：BioMed research international

authors： Mitchelson AJ,Wilson CJ,Mihalko WM,Grupp TM,Manning BT,Dennis DA,Goodman SB,Tzeng TH,Vasdev S,Saleh KJ

更新日期：2015-01-01 00:00:00

abstract：:Liver regeneration after partial hepatectomy (PH) is a highly orchestrated biological process in which synchronized hepatocyte proliferation is induced after massive liver mass loss. Hepatocyte proliferation could be regulated by multiple signals, such as miRNAs and autophagy, but underlying mechanism remains unclear....

journal_title：BioMed research international

authors： Lu T,Hao J,Shen C,Gu G,Zhang J,Xu N

更新日期：2018-07-31 00:00:00

abstract：:Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...

journal_title：BioMed research international

authors： Leem KH,Kim SA,Park HJ

更新日期：2020-10-17 00:00:00

abstract：:This study aimed at clarifying the mechanism and role of survivin in hypoxia-induced multidrug resistance (MDR) of laryngeal carcinoma cells. Human laryngeal cancer cells were incubated under hypoxia or normoxia. The expression of survivin was silenced by performing RNA interference. Additionally, by Western blot and ...

journal_title：BioMed research international

authors： Xu D,Li DW,Xie J,Chen XW

更新日期：2019-04-24 00:00:00

abstract：:Cervical cancer is one of the malignant tumors that seriously threaten women's health. The mechanism of development needs to be deeply studied. In recent years, lncRNA has been identified as one of the important factors affecting the malignant progression of tumors. In this study, we illustrated the important mechanis...

journal_title：BioMed research international

authors： Hu T,Zhang Q,Gao L

更新日期：2020-01-03 00:00:00

abstract：Introduction:To identify and analyze factors that influence administration, recognition, and compliance of medicine among community residents in Jilin Province, China. Methods:A survey was carried out among 2417 community residents in Jilin Province, China, to study their administration (CRA), recognition (CRR), and c...

journal_title：BioMed research international

authors： Song YQ,Zhang WR,Zhang SX,Wang TH,Jiang Z,Meng CF,Zhang TZ,Xin QZ,Cao KJ,Zhang Y,Sun Y

更新日期：2020-07-18 00:00:00

abstract：Objectives:The aim of this study was to evaluate the influence of ferule and the post type on the fracture strength and stress distribution in premolars. Materials and Methods:Forty human mandibular premolars were decoronated, allocated in four groups, and restored as follows: CPC-NF: cast post-and-core and absence of...

journal_title：BioMed research international

authors： Bacchi A,Caldas RA,Schmidt D,Detoni M,Matheus Albino Souza,Cecchin D,Farina AP

更新日期：2019-01-03 00:00:00

abstract：:This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic pre...

journal_title：BioMed research international

authors： Shen J,Shen J,Huang K,Wu Y,Pan J,Zhan R

更新日期：2019-03-19 00:00:00

abstract：:Schistosomiasis is one of the world's major public health problems. Praziquantel is currently the only effective drug against schistosomiasis. As resistance of praziquantel has emerged in some endemic areas, development of new antischistosomal agents should be a high priority. In this study, a phage display peptide li...

journal_title：BioMed research international

authors： Song LJ,Li JH,Yin XR,Zhang W,Jin Y,Gao H,Wang J,Yu CX,Hua ZC

更新日期：2018-06-05 00:00:00

abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

journal_title：BioMed research international

authors： Kaur K,Kaur G

更新日期：2013-01-01 00:00:00

abstract：:Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...

journal_title：BioMed research international

authors： Léonard B,Kridelka F,Delbecque K,Goffin F,Demoulin S,Doyen J,Delvenne P

更新日期：2014-01-01 00:00:00

abstract：:The present work reports the anticancer, antioxidant, lipo-protective, and anti-HIV activities of phytoconstituents present in P. hysterophorus leaf. Dried leaf samples were sequentially extracted with nonpolar and polar solvents. Ethanol fraction showed noticeable cytotoxic activity (81-85%) in SRB assay against MCF-...

journal_title：BioMed research international

authors： Kumar S,Chashoo G,Saxena AK,Pandey AK

更新日期：2013-01-01 00:00:00

abstract：:Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...

journal_title：BioMed research international

authors： Veryser L,Bracke N,Wynendaele E,Joshi T,Tatke P,Taevernier L,De Spiegeleer B

更新日期：2016-01-01 00:00:00

abstract：Background:Anion gap (AG) has been proved to be associated with prognosis of many cardiovascular diseases. This study is aimed at exploring the association of AG with inhospital all-cause mortality and adverse clinical outcomes in coronary care unit (CCU) patients. Method:All data of this study was extracted from Medi...

journal_title：BioMed research international

authors： Sun T,Cai C,Shen H,Yang J,Guo Q,Zhang J,Zhang B,Ding Y,Zhou Y

更新日期：2020-08-27 00:00:00

abstract：OBJECTIVE:There is an unmet need for a specific cardiovascular risk (CV) algorithm for rheumatoid arthritis (RA) patients. Lipoprotein data are often not available in RA cohorts but could be obtained from frozen blood samples. The objective of this study was to estimate the storage effect on lipoproteins in long-term (...

journal_title：BioMed research international

authors： Arts EE,Popa CD,Smith JP,Arntz OJ,van de Loo FA,Donders R,Semb AG,Kitas GD,van Riel PL,Fransen J

更新日期：2014-01-01 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：:Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful fo...

journal_title：BioMed research international

authors： Henriquez-Camacho C,Losa J

更新日期：2014-01-01 00:00:00

abstract：:The effects of obstruction on renal function are the consequence of many factors that profoundly alter all components of glomerular function. Besides the acute effects on glomerular filtration rate and tubule function, a chronic obstruction induces tubular and interstitial injury that results from the activation of di...

journal_title：BioMed research international

authors： Lucarelli G,Mancini V,Galleggiante V,Rutigliano M,Vavallo A,Battaglia M,Ditonno P

更新日期：2014-01-01 00:00:00

abstract：Background:Reproductive system cancer is an important cause of morbidity and mortality worldwide which threatens women's health and lives. Breast, cervical, and ovarian cancer have the higher incidence and mortality among a series of gynecology malignant tumor. We aimed to compare and assess the temporal trends of comm...

journal_title：BioMed research international

authors： Wang J,Lv H,Xue Z,Wang L,Bai Z

更新日期：2018-03-21 00:00:00

abstract：Objective:We identified differentially expressed microRNAs (DEMs) between esophageal carcinoma (ESCA) tissues and normal esophageal tissues. We then constructed a novel three-miRNA signature to predict the prognosis of ESCA patients using bioinformatics analysis. Materials and Methods. We combined two microarray profil...

journal_title：BioMed research international

authors： Wu K,Zhang C,Zhang C,Dai D

更新日期：2020-02-10 00:00:00