5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure.

abstract：:Insecticides are still largely applied in public health to control disease vectors. In Brazil, organophosphates (OP) and pyrethroids (PY) are used against Aedes aegypti for years. Since 2009 Insect Growth Regulators (IGR) are also employed in the control of larvae. We quantified resistance to temephos (OP), deltamethr...

journal_title：BioMed research international

authors： Bellinato DF,Viana-Medeiros PF,Araújo SC,Martins AJ,Lima JB,Valle D

更新日期：2016-01-01 00:00:00

abstract：:Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal stem cells (MSCs) sourced from several different cord regions, inclu...

journal_title：BioMed research international

authors： Mennan C,Wright K,Bhattacharjee A,Balain B,Richardson J,Roberts S

更新日期：2013-01-01 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：:Ampelopsis brevipedunculata (Maxim.) Trautv. (AB), a traditional East Asian medicine, exhibits protective effects against several inflammatory diseases. Our search for an inhibitor of IL-6-induced JAK2/STAT3 activation revealed that AB ethanolic extract (ABE) had a significant inhibitory effect on IL-6-induced STAT3 e...

journal_title：BioMed research international

authors： Jang HJ,Lee SJ,Lim HJ,Jung K,Lee S,Park CS,Lee SW,Rho MC

更新日期：2018-06-10 00:00:00

abstract：:T-cell acute lymphoblastic leukemia (T-ALL) is a complex disease, resulting from proliferation of differentially arrested immature T cells. The molecular mechanisms and the genes involved in the generation of T-ALL remain largely undefined. In this study, we propose a set of genes to differentiate individuals with T-A...

journal_title：BioMed research international

authors： Maiorov EG,Keskin O,Ng OH,Ozbek U,Gursoy A

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to detect oral bacteremia and offer the antibiotic resistance patterns. Bacterial resistance pattern was evaluated in 50 patients. A spectrophotometer device equipped with UV and electrophoresis of the extracted samples on agarose gel for antibiogram test were used. PCR test 15 minutes after ...

journal_title：BioMed research international

authors： Rezazadeh F,Azad A,Khorami A,Modaresi F,Rezaie Z

更新日期：2020-10-01 00:00:00

abstract：Background:Comparison of single-level open and minimally invasive transforaminal lumbar interbody fusions (O-TLIF and MI-TLIF) of a single surgeon and presentation of his MI-TLIF learning curve in a retrospective observational cohort study. Methods:27 MI-TLIF and 31 O-TLIF patients, performed between 03/01/2013 and 03...

journal_title：BioMed research international

authors： Kovari VZ,Kuti A,Konya K,Szel I,Szekely AK,Szalay K

更新日期：2020-01-25 00:00:00

abstract：:Upon allergen challenge, DC subsets are recruited to target sites under the influence of chemotactic agents; however, details pertinent to their trafficking remain largely unknown. We investigated the kinetic profiles of blood and skin-infiltrating DC subsets in twelve atopic subjects receiving six weekly intradermal ...

journal_title：BioMed research international

authors： Vittorakis S,Samitas K,Tousa S,Zervas E,Aggelakopoulou M,Semitekolou M,Panoutsakopoulou V,Xanthou G,Gaga M

更新日期：2014-01-01 00:00:00

abstract：:Cerenkov luminescence imaging (CLI) can provide information of medical radionuclides used in nuclear imaging based on Cerenkov radiation, which makes it possible for optical means to image clinical radionuclide labeled probes. However, the exceptionally weak Cerenkov luminescence (CL) from Cerenkov radiation is suscep...

journal_title：BioMed research international

authors： Cao X,Li Y,Zhan Y,Chen X,Kang F,Wang J,Liang J

更新日期：2016-01-01 00:00:00

abstract：Background:The kaya business is known to pose significant health-related risks to female migrants. This study sought to explore the health-related concerns of female head porters in the Mallam Atta market, Accra, Ghana. Methods:A qualitative study was conducted in which twenty female head porters at the Mallam Atta ma...

journal_title：BioMed research international

authors： Nyarko SH,Tahiru AM

更新日期：2018-02-13 00:00:00

abstract：:C-type lectins are multifunctional sugar-binding molecules expressed on dendritic cells (DCs) and macrophages that internalize antigens for processing and presentation. Macrophage galactose-type lectin 1 (MGL1) recognizes glycoconjugates expressing Lewis X structures which contain galactose residues, and it is selecti...

journal_title：BioMed research international

authors： Montero-Barrera D,Valderrama-Carvajal H,Terrazas CA,Rojas-Hernández S,Ledesma-Soto Y,Vera-Arias L,Carrasco-Yépez M,Gómez-García L,Martínez-Saucedo D,Becerra-Díaz M,Terrazas LI

更新日期：2015-01-01 00:00:00

abstract：:Stressful events can have both short- and long-term effects on the brain. Our recent investigation identified short-term white matter integrity (WMI) changes in 30 subjects soon after the Japanese earthquake. Our findings suggested that lower WMI in the right anterior cingulum (Cg) was a pre-existing vulnerability fac...

journal_title：BioMed research international

authors： Sekiguchi A,Kotozaki Y,Sugiura M,Nouchi R,Takeuchi H,Hanawa S,Nakagawa S,Miyauchi CM,Araki T,Sakuma A,Taki Y,Kawashima R

更新日期：2014-01-01 00:00:00

abstract：Background:It is well known that the programmed intermittent epidural bolus (PIEB) technique effectively provides epidural anesthesia in labor. This randomized double-blind trial compared the postoperative analgesic efficacy of PIEB with that of continuous epidural infusion (CEI) in patients undergoing gynecological su...

journal_title：BioMed research international

authors： Satomi S,Kakuta N,Murakami C,Sakai Y,Tanaka K,Tsutsumi YM

更新日期：2018-05-15 00:00:00

abstract：:Acute nonspecific, or primary, mesenteric lymphadenitis is a self-limiting inflammatory condition affecting the mesenteric lymph nodes, whose presentation mimics appendicitis or intussusception. It typically occurs in children, adolescents, and young adults. White blood count and C-reactive protein are of limited usef...

journal_title：BioMed research international

authors： Helbling R,Conficconi E,Wyttenbach M,Benetti C,Simonetti GD,Bianchetti MG,Hamitaga F,Lava SA,Fossali EF,Milani GP

更新日期：2017-01-01 00:00:00

abstract：:It is of great importance to prepare multifunctional scaffolds combining good mechanical strength, bioactivity, and drug delivery ability for bone tissue engineering. In this study, nanosized mesoporous bioglass/poly(lactic-co-glycolic acid) composite-coated calcium silicate scaffolds, named NMBG-PLGA/CS, were success...

journal_title：BioMed research international

authors： Shi M,Zhai D,Zhao L,Wu C,Chang J

更新日期：2014-01-01 00:00:00

abstract：:Densitometry data generated for Western blots are commonly used to compare protein abundance between samples. In the last decade, it has become apparent that assumptions underpinning these comparisons are often violated in studies reporting Western blot data in the literature. These violations can lead to erroneous in...

journal_title：BioMed research international

authors： Butler TAJ,Paul JW,Chan EC,Smith R,Tolosa JM

更新日期：2019-01-21 00:00:00

abstract：:Family planning coverage has improved in Ethiopia in the last decade, though fertility is still about 5.8 in the rural setup. In this paper, the major structural determinants of family planning service were analyzed using a multilevel model from 8906 individual women observation in the 2011 EDHS data. The results show...

journal_title：BioMed research international

authors： Gizachew Balew J,Cho Y,Tammy Kim C,Ko W

更新日期：2015-01-01 00:00:00

abstract：:Objectives. To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Methods. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Agi...

journal_title：BioMed research international

authors： Pérez-Zepeda MU,Cesari M,Carrillo-Vega MF,Salinas-Escudero G,Tella-Vega P,García-Peña C

更新日期：2017-01-01 00:00:00

abstract：:Purpose. The aim of the present study was to elucidate the metabolic mechanisms associated with chronic fatigue syndrome (CFS) via an analysis of urine metabolites prior to and following exercise in a rat model. Methods. A rat model of CFS was established using restraint-stress, forced exercise, and crowded and noisy ...

journal_title：BioMed research international

authors： Shao C,Ren Y,Wang Z,Kang C,Jiang H,Chi A

更新日期：2017-01-01 00:00:00

abstract：:Objective. Our objective is to develop a computerized scheme for liver tumor segmentation in MR images. Materials and Methods. Our proposed scheme consists of four main stages. Firstly, the region of interest (ROI) image which contains the liver tumor region in the T1-weighted MR image series was extracted by using se...

journal_title：BioMed research international

authors： Le TN,Bao PT,Huynh HT

更新日期：2016-01-01 00:00:00

abstract：:Solid lipid nanoparticle is an efficient lipid based drug delivery system which can enhance the bioavailability of poorly water soluble drugs. Efavirenz is a highly lipophilic drug from nonnucleoside inhibitor category for treatment of HIV. Present work illustrates development of an SLN formulation for Efavirenz with ...

journal_title：BioMed research international

authors： Gaur PK,Mishra S,Bajpai M,Mishra A

更新日期：2014-01-01 00:00:00

abstract：:The expression profile of long noncoding RNA (lncRNA) in human epicardial adipose tissue (EAT) has not been widely studied. In the present study, we performed RNA sequencing to analyze the expression profiles of lncRNA and mRNA in EAT in coronary artery disease (CAD) patients with and without heart failure (HF). Our r...

journal_title：BioMed research international

authors： Zheng M,Zhao L,Yang X

更新日期：2019-07-04 00:00:00

abstract：:The study investigated the vertical jump landing limb symmetry after ACLR between a group of patients receiving a longer supervised physiotherapeutic procedure and following a shorter supervised physiotherapy. Group I (n = 20) and Group II (n = 15) were males averagely 30 weeks after ACLR. The time since ACLR in both ...

journal_title：BioMed research international

authors： Królikowska A,Czamara A,Szuba Ł,Reichert P

更新日期：2018-04-23 00:00:00

abstract：Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

journal_title：BioMed research international

authors： Zhang L,Song X,Li X,Wu C,Jiang J

更新日期：2018-11-14 00:00:00

abstract：:The quantitative and reproducible analysis of the standard body movement in Tai Chi Chuan (TCC) was performed in this study. We aimed to provide a reference of the upper extremities for standardizing TCC practice. Microsoft Kinect was used to record the motion during the practice of TCC. The preparation form and eight...

journal_title：BioMed research international

authors： Ho TJ,Chou KT,Li CH,Kuo BC,Huang TC

更新日期：2018-01-29 00:00:00

abstract：:Rapid bone defect filling with normal bone is a challenge in orthopaedics and dentistry. Strontium ranelate (SrRan) has been shown to in vitro decrease bone resorption and increase bone formation, and represents a potential agent with the capacity to accelerate bone defect filling. In this study, bone tibial defects o...

journal_title：BioMed research international

authors： Zacchetti G,Dayer R,Rizzoli R,Ammann P

更新日期：2014-01-01 00:00:00

abstract：:DNA methylation primarily occurs on CpG dinucleotides and plays an important role in transcriptional regulations during tissue development and cell differentiation. Over 25% of CpG dinucleotides in the human genome reside within Alu elements, the most abundant human repeats. The methylation of Alu elements is an impor...

journal_title：BioMed research international

authors： Luo Y,Lu X,Xie H

更新日期：2014-01-01 00:00:00

abstract：:The regiospecific distribution of fatty acids (FAs) and composition of triglyceride (TAG) molecular species of fishes were analyzed and calculated by pancreatic lipase (PL) hydrolysis and Visual Basic (VB) program. DHA was preferentially located at sn-2 position in TAG molecule, whereas EPA was almost equally distribu...

journal_title：BioMed research international

authors： Zhang H,Shen Y,Zhang Y,Li L,Wang X

更新日期：2018-01-29 00:00:00

abstract：:Surgical flaps are frequently affected by ischemia/reperfusion (I/R) injury. Calcium-sensing receptor (CaSR) and stromal cell-derived factor-1α (SDF-1α) are closely associated with myocardial I/R injury. This study was performed to evaluate the feasibility of applying SDF-1α to counteract CaSR activation-mediated I/R ...

journal_title：BioMed research international

authors： Song L,Gao LN,Wang J,Thapa S,Li Y,Zhong XB,Zhao HW,Xiang XR,Zhang FG,Ji P

更新日期：2018-01-11 00:00:00

abstract：Introduction:An increased number of survivors have emerged from the 2014 West African Ebola Virus Disease (EVD) epidemic. Post-Ebola Syndrome (PES) is a group of physical and psychological symptoms affecting EVD survivors. This study aimed to estimate the prevalence of PES among EVD survivors in Montserrado County, Lib...

journal_title：BioMed research international

authors： Wilson HW,Amo-Addae M,Kenu E,Ilesanmi OS,Ameme DK,Sackey SO

更新日期：2018-06-28 00:00:00