A Frailty Index from Next-of-Kin Data: A Cross-Sectional Analysis from the Mexican Health and Aging Study.

Abstract:

:Objectives. To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Methods. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Aging Study (MHAS). Measurements. Along with descriptive statistics, the frailty index (FI) was tested in regression models to assess its association with adverse outcomes previous to death: number of hospitalized days in the previous year and number of visits to a physician in the previous year, in unadjusted and adjusted models. Results. From a total of 2,649 individuals the mean of age was 74.8 (±11.4) and 56.3% (n = 1,183) were women. The mean of the FI was of 0.279 (±SD 0.131, R = 0.0-0.738) and distribution was biased to the right. There was a significant association (p < 0.001) between the FI and number of hospitalized days (β = 45.7, 95% CI 36.1-55.4, p < 0.001) and for the number of visits to a physician (β = 25.93, 95% CI 19.27-32.6, p < 0.001) both models adjusted for age and sex. Conclusion. The FI constructed with next-of-kin data showed similar characteristics to similar indexes of older adults. It was independently associated with health care use.

journal_name

Biomed Res Int

authors

Pérez-Zepeda MU,Cesari M,Carrillo-Vega MF,Salinas-Escudero G,Tella-Vega P,García-Peña C

doi

10.1155/2017/6069374

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

6069374

eissn

2314-6133

issn

2314-6141

journal_volume

2017

pub_type

杂志文章
  • Endowing iPSC-Derived MSCs with Angiogenic and Keratinogenic Differentiation Potential: A Promising Cell Source for Skin Tissue Engineering.

    abstract::Induced pluripotent stem cells (iPSC) hold tremendous potential for personalized cell-based therapy for skin regeneration. Aiming to establish human iPSCs as a potential cell source for skin tissue engineering, we expect to obtain an epidermal-like cell line with angiogenic and keratinogenic differentiation potential ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/8459503

    authors: Lin W,Chen M,Hu C,Qin S,Chu C,Xiang L,Man Y,Qu Y

    更新日期:2018-09-13 00:00:00

  • Surface modifications of dental ceramic implants with different glass solder matrices: in vitro analyses with human primary osteoblasts and epithelial cells.

    abstract::Ceramic materials show excellent esthetic behavior, along with an absence of hypersensitivity, making them a possible alternative implant material in dental surgery. However, their surface properties enable only limited osseointegration compared to titanium implants. Within this study, a novel surface coating techniqu...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/742180

    authors: Markhoff J,Mick E,Mitrovic A,Pasold J,Wegner K,Bader R

    更新日期:2014-01-01 00:00:00

  • The Expression and Correlation of iNOS and p53 in Oral Squamous Cell Carcinoma.

    abstract::Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer. Inducible nitric oxide synthase (iNOS) and p53 are associated with a variety of human cancers, but their expression and interaction in OSCC have not been fully explored. In this study, we investigated the expression of iNOS and p53 in OSCC ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/637853

    authors: Yang L,Wang Y,Guo L,Wang L,Chen W,Shi B

    更新日期:2015-01-01 00:00:00

  • Two-dimensional PCA highlights the differentiated antitumor and antimicrobial activity of methanolic and aqueous extracts of Laurus nobilis L. from different origins.

    abstract::Natural matrices are important sources of new antitumor and antimicrobial compounds. Species such as Laurus nobilis L. (laurel) might be used for this purpose, considering its medicinal properties. Herein, in vitro activity against human tumor cell lines, bacteria, and fungi was evaluated in enriched phenolic extracts...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/520464

    authors: Dias MI,Barreira JC,Calhelha RC,Queiroz MJ,Oliveira MB,Soković M,Ferreira IC

    更新日期:2014-01-01 00:00:00

  • Autologous bone marrow mesenchymal stem cells associated with tantalum rod implantation and vascularized iliac grafting for the treatment of end-stage osteonecrosis of the femoral head.

    abstract::Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA). However, there have been unsatisfactory success rates for end-stage ONFH. The auth...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2015/240506

    authors: Zhao D,Liu B,Wang B,Yang L,Xie H,Huang S,Zhang Y,Wei X

    更新日期:2015-01-01 00:00:00

  • Tanshinone IIA induces apoptosis in human oral cancer KB cells through a mitochondria-dependent pathway.

    abstract::Tanshinone IIA (Tan IIA), an active phytochemical in the dried root of Salvia miltiorrhiza Bunge, has shown an antiproliferative activity on various human cancer cell lines including nasopharyngeal carcinoma cells. However, the effects of Tan IIA on human oral cancer cells are still unknown. This study aimed to invest...

    journal_title:BioMed research international

    pub_type: 杂志文章,收录出版

    doi:10.1155/2014/540516

    authors: Tseng PY,Lu WC,Hsieh MJ,Chien SY,Chen MK

    更新日期:2014-01-01 00:00:00

  • Performance study of chromium (VI) removal in presence of phenol in a continuous packed bed reactor by Escherichia coli isolated from East Calcutta Wetlands.

    abstract::Organic pollutants, like phenol, along with heavy metals, like chromium, are present in various industrial effluents that pose serious health hazard to humans. The present study looked at removal of chromium (VI) in presence of phenol in a counter-current continuous packed bed reactor packed with E. coli cells immobil...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/373412

    authors: Chakraborty B,Indra S,Hazra D,Betai R,Ray L,Basu S

    更新日期:2013-01-01 00:00:00

  • Adenosine Generated by Regulatory T Cells Induces CD8+ T Cell Exhaustion in Gastric Cancer through A2aR Pathway.

    abstract:Background:Adenosine, derived from the degradation of ATP via ectonucleotidases CD39 and CD73, is a critical immunosuppressive metabolite in the hypoxic microenvironment of tumor tissue. Adenosine signaling via A2aR can inhibit the antitumor immune response of CD8+ T cells. CD39 and CD73 high-expressing Tregs play a cr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/4093214

    authors: Shi L,Feng M,Du S,Wei X,Song H,Yixin X,Song J,Wenxian G

    更新日期:2019-12-14 00:00:00

  • Single nucleotide polymorphism in the promoter of the human interleukin-13 gene is associated with asthma in Malaysian adults.

    abstract::Asthma susceptibility genes are mapped to a region on human chromosome 5q31-q33, which contains a cluster of proinflammatory cytokine genes such as interleukin-13 (IL-13), which is associated with asthma. This study investigated the allele frequencies of two single nucleotide polymorphisms (SNPs) (-1111C>T and 4257C>A...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/981012

    authors: Radhakrishnan AK,Raj VL,Tan LK,Liam CK

    更新日期:2013-01-01 00:00:00

  • The role of M1 and M2 macrophages in prostate cancer in relation to extracapsular tumor extension and biochemical recurrence after radical prostatectomy.

    abstract:INTRODUCTION:The aim of our work was to investigate the causal connection between M1 and M2 macrophage phenotypes occurrence and prostate cancer, their correlation with tumor extension (ECE), and biochemical recurrence (BR). PATIENT AND METHODS:Clinical and pathological data were prospectively gathered from 93 patient...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/486798

    authors: Lanciotti M,Masieri L,Raspollini MR,Minervini A,Mari A,Comito G,Giannoni E,Carini M,Chiarugi P,Serni S

    更新日期:2014-01-01 00:00:00

  • The potential of microRNAs in personalized medicine against cancers.

    abstract::MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular processes. Their deregulation is thus often causative of human malignancies, including cancers. Numerous studies have implicated microRNAs in the different steps of tumorigenesis including initiation, progression, metastasis, and ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/642916

    authors: Saumet A,Mathelier A,Lecellier CH

    更新日期:2014-01-01 00:00:00

  • Systematic Exposition of Mesenchymal Stem Cell for Inflammatory Bowel Disease and Its Associated Colorectal Cancer.

    abstract::Mesenchymal stem cells (MSCs) therapy has been applied to a wide range of diseases with excessive immune response, including inflammatory bowel disease (IBD), owing to its powerful immunosuppression and its ability to repair tissue lesions. Different sources of MSCs show different therapeutic properties. Engineering m...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/9652817

    authors: Kang J,Zhang L,Luo X,Ma X,Wang G,Yang Y,Yan Y,Qian H,Zhang X,Xu W,Mao F

    更新日期:2018-12-26 00:00:00

  • Potential Role of the Last Half Repeat in TAL Effectors Revealed by a Molecular Simulation Study.

    abstract::TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dynamics simulations ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8036450

    authors: Wan H,Chang S,Hu JP,Tian XH,Wang MH

    更新日期:2016-01-01 00:00:00

  • Stem Cells as Potential Targets of Polyphenols in Multiple Sclerosis and Alzheimer's Disease.

    abstract::Alzheimer's disease (AD) and multiple sclerosis are major neurodegenerative diseases, which are characterized by the accumulation of abnormal pathogenic proteins due to oxidative stress, mitochondrial dysfunction, impaired autophagy, and pathogens, leading to neurodegeneration and behavioral deficits. Herein, we revie...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/1483791

    authors: Tandon A,Singh SJ,Chaturvedi RK

    更新日期:2018-07-12 00:00:00

  • Effects of Physical Activity Programs on the Improvement of Dementia Symptom: A Meta-Analysis.

    abstract::Objective. To confirm that physical activity program improves the symptoms of dementia and the most effective physical activity was selected to help establish exercise programs. Methods. Three databases, PubMed, Science Direct, and Willey online, were used to collect articles. The databases were published between Janu...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2016/2920146

    authors: Lee HS,Park SW,Park YJ

    更新日期:2016-01-01 00:00:00

  • Early aging in Chernobyl clean-up workers: long-term study.

    abstract::This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/948473

    authors: Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

    更新日期:2015-01-01 00:00:00

  • Prevalence of anaemia among pregnant women at booking in the University of Uyo Teaching Hospital, Uyo, Nigeria.

    abstract:BACKGROUND:Anaemia with an estimated prevalence of 35-75% among pregnant women is a major cause of maternal deaths in Nigeria. objective: To determine the prevalence of anaemia, associated sociodemographic factors and red cell morphological pattern among pregnant women during booking at the University Teaching Hospital...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/849080

    authors: Olatunbosun OA,Abasiattai AM,Bassey EA,James RS,Ibanga G,Morgan A

    更新日期:2014-01-01 00:00:00

  • The Influence of Humidity on Assessing Irritation Threshold of Ammonia.

    abstract::A large number of occupational exposure limit values (OELs) are based on avoiding of sensory irritation of the eyes and the upper respiratory tract. In order to investigate the chemosensory effect range of a chemical, odor and sensory irritation thresholds (lateralization thresholds, LTs) can be assessed. Humidity aff...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2016/6015761

    authors: Monsé C,Sucker K,Hoffmeyer F,Jettkant B,Berresheim H,Bünger J,Brüning T

    更新日期:2016-01-01 00:00:00

  • The Prevalence and Replication Capacity of a Tibetan Dominant HBV Strain, C/D Recombinant.

    abstract::This study aimed to estimate the distribution of hepatitis B virus (HBV) C/D recombinant in Han and Tibet patients with chronic hepatitis B (CHB) and then learn such strain's replication capacity in vivo. A total of 331 serum samples were collected from Han outpatients from Sichuan Province and Tibetan outpatients fro...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/8415907

    authors: Du L,Liu M,Liu M,Zhou T,Cheng X,Liu C,Tang H

    更新日期:2017-01-01 00:00:00

  • Integron-Mediated Antibiotic Resistance in Acinetobacter baumannii Isolated from Intensive Care Unit Patients, Babol, North of Iran.

    abstract:BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/7157923

    authors: Deylam Salehi M,Ferdosi-Shahandashti E,Yahyapour Y,Khafri S,Pournajaf A,Rajabnia R

    更新日期:2017-01-01 00:00:00

  • Ten-Year Surgical Outcomes and Prognostic Factors for French-Door Laminoplasty in the Treatment of Multilevel Cervical Spondylotic Myelopathy.

    abstract:Objective:To analyze the ten-year surgical outcomes and postoperative complications of French-Door laminoplasty (FDL) in the management of multilevel cervical spondylotic myelopathy (MCSM) and analyze the prognostic factors for FDL in treating MCSM. Methods:64 patients with MCSM, who were operated by FDL, were include...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/3627071

    authors: Chen G,Liu X,Chen N,Chen B,Zou X,Wei F,Liu S

    更新日期:2020-05-06 00:00:00

  • An experimental approach for selecting appropriate rodent diets for research studies on metabolic disorders.

    abstract::Diverse high energy diets have been utilized to precipitate obesity and related metabolic disorders in rodent models, though the dietary intervention has not absolutely been standardized. The present study established usage of a customized semipurified normal control diet (NCD) and high fat diet (HFD), for research st...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/752870

    authors: Sasidharan SR,Joseph JA,Anandakumar S,Venkatesan V,Ariyattu Madhavan CN,Agarwal A

    更新日期:2013-01-01 00:00:00

  • The Ultrasonographic Features of Shoulder Pain Patients in a Tertiary Hospital in South China.

    abstract:Methods:Patients with shoulder pain were recruited in an outpatient rehabilitation clinic at the Third Affiliated Hospital of Sun Yat-Sen University from January 1, 2017, to June 30, 2018. These shoulder pain patients with or without limitation in joint movement can be included in the study. All of them received muscul...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/3024793

    authors: Jiang L,He J,Chen CPC,Xie D,Mai Y,Yue B,Dou Z

    更新日期:2020-08-25 00:00:00

  • Regiospecific Analysis of Fatty Acids and Calculation of Triglyceride Molecular Species in Marine Fish Oils.

    abstract::The regiospecific distribution of fatty acids (FAs) and composition of triglyceride (TAG) molecular species of fishes were analyzed and calculated by pancreatic lipase (PL) hydrolysis and Visual Basic (VB) program. DHA was preferentially located at sn-2 position in TAG molecule, whereas EPA was almost equally distribu...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/9016840

    authors: Zhang H,Shen Y,Zhang Y,Li L,Wang X

    更新日期:2018-01-29 00:00:00

  • The pilot study of fibrin with temporomandibular joint derived synovial stem cells in repairing TMJ disc perforation.

    abstract::TMJ disc related diseases are difficult to be cured due to the poor repair ability of the disc. TMJ-SDSCs were ideal cell sources for cartilage tissue engineering which have been widely used in hyaline cartilage regeneration. Fibrin gel has been demonstrated as a potential scaffold for neocartilage formation. The aim ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/454021

    authors: Wu Y,Gong Z,Li J,Meng Q,Fang W,Long X

    更新日期:2014-01-01 00:00:00

  • Chair-based exercises for frail older people: a systematic review.

    abstract:INTRODUCTION:Frail older people are often unable to undertake high-intensity exercise programmes. Chair-based exercises (CBEs) are used as an alternative, for which health benefits are uncertain. OBJECTIVE:To examine the effects of CBE programmes for frail older people through a systematic review of existing literatur...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/309506

    authors: Anthony K,Robinson K,Logan P,Gordon AL,Harwood RH,Masud T

    更新日期:2013-01-01 00:00:00

  • Natural Language Processing Based Instrument for Classification of Free Text Medical Records.

    abstract::According to the Ministry of Labor, Health and Social Affairs of Georgia a new health management system has to be introduced in the nearest future. In this context arises the problem of structuring and classifying documents containing all the history of medical services provided. The present work introduces the instru...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8313454

    authors: Khachidze M,Tsintsadze M,Archuadze M

    更新日期:2016-01-01 00:00:00

  • Clinical Decision-Making in Chronic Spine Pain: Dilemma of Image-Based Diagnosis of Degenerative Spine and Generation Mechanisms for Nociceptive, Radicular, and Referred Pain.

    abstract:Background:Spine-related pain is a complex heterogeneous condition. Excessive reliance on radiological imaging might lead to overdiagnosis of incidental asymptomatic spinal changes and unnecessary surgery. Approaches to the clinical management of spine pain should (1) identify pain generators, types, patterns, and mech...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/8793843

    authors: Eloqayli H

    更新日期:2018-12-17 00:00:00

  • Association of Toll-like receptor 4 polymorphisms with diabetic foot ulcers and application of artificial neural network in DFU risk assessment in type 2 diabetes patients.

    abstract::The Toll-Like receptor 4 (TLR4) plays an important role in immunity, tissue repair, and regeneration. The objective of the present work was to evaluate the association of TLR4 single nucleotide polymorphisms (SNPs) rs4986790, rs4986791, rs11536858 (merged into rs10759931), rs1927911, and rs1927914 with increased diabe...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/318686

    authors: Singh K,Singh VK,Agrawal NK,Gupta SK,Singh K

    更新日期:2013-01-01 00:00:00

  • Development of microencapsulation delivery system for long-term preservation of probiotics as biotherapeutics agent.

    abstract::The administration of probiotic bacteria for health benefit has rapidly expanded in recent years, with a global market worth $32.6 billion predicted by 2014. The oral administration of most of the probiotics results in the lack of ability to survive in a high proportion of the harsh conditions of acidity and bile conc...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/620719

    authors: Solanki HK,Pawar DD,Shah DA,Prajapati VD,Jani GK,Mulla AM,Thakar PM

    更新日期:2013-01-01 00:00:00