Expression sensitivity analysis of human disease related genes.

abstract：INTRODUCTION:Our study aims to determine the prevalence of nicotine dependence and investigate the effect of nicotine dependence on psychopathology among schizophrenia patients. METHODS:A cross-sectional study was carried out in an outpatient psychiatric clinic at a general hospital in Malaysia. 180 recruited subjects...

journal_title：BioMed research international

authors： Yee A,Bt Nek Mohamed NN,Binti Hashim AH,Loh HS,Harbajan Singh MK,Ng CG,Jambunathan ST

更新日期：2015-01-01 00:00:00

abstract：:Owing to its hydrophilicity, negative charge, small size, and labile degradation by endogenous nucleases, small interfering RNA (siRNA) delivery must be achieved by a carrier system. In this study, cationic copolymers composed of low-molecular-weight polyethylenimine and polythiophenes were synthesized and evaluated a...

journal_title：BioMed research international

authors： He P,Hagiwara K,Chong H,Yu HH,Ito Y

更新日期：2015-01-01 00:00:00

abstract：:The myostatin (MSTN) is a known negative growth regulator of skeletal muscle. The mutated myostatin showed a double-muscular phenotype having a positive significance for the farmed animals. Consequently, adequate information is not available in the teleosts, including farmed rohu carp, Labeo rohita. In the absence of ...

journal_title：BioMed research international

authors： Rasal KD,Chakrapani V,Patra SK,Mohapatra SD,Nayak S,Jena S,Sundaray JK,Jayasankar P,Barman HK

更新日期：2016-01-01 00:00:00

abstract：:Background. The aim of this study was to assess the effects of low concentrations of H2O2 on angiogenesis of human umbilical vein endothelial cells (HUVECs) in vitro and explore the underlying mechanisms. Methods. HUVECs were cultured and stimulated with different concentrations of H2O2. Flow cytometric analysis was u...

journal_title：BioMed research international

authors： Jiang S,Zhang D,Huang H,Lei Y,Han Y,Han W

更新日期：2017-01-01 00:00:00

abstract：:Our research investigates the serum levels of three angiogenic factors in the AF family, namely, placenta growth factor (PlGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF), in 54 patients with SLE (SLE group) and 28 healthy controls (normal control) through ELISA measurement. A...

journal_title：BioMed research international

authors： Zhou L,Lu G,Shen L,Wang L,Wang M

更新日期：2014-01-01 00:00:00

abstract：:Human amniotic fluid and a mixture of eight fatty acids (FAT-M) identified in this maternal fluid (C12:0, lauric acid, 0.9 μ g%; C14:0, myristic acid, 6.9 μ g%; C16:0, palmitic acid, 35.3 μ g%; C16:1, palmitoleic acid, 16.4 μ g%; C18:0, stearic acid, 8.5 μ g%; C18:1 cis, oleic acid, 18.4 μ g%; C18:1 trans, elaidic aci...

journal_title：BioMed research international

authors： Rodríguez-Landa JF,García-Ríos RI,Cueto-Escobedo J,Bernal-Morales B,Contreras CM

更新日期：2013-01-01 00:00:00

abstract：:Embryology of normal web space creation and the genetics of syndactyly in humans and experimental animals are well described in the literature. In this review, the author offers a 3-step pathway of pathogenesis for syndactyly. The first step is initiated either by the overactivation of the WNT canonical pathway or the...

journal_title：BioMed research international

authors： Al-Qattan MM

更新日期：2019-09-15 00:00:00

abstract：:Ablative therapies have been utilized with increasing frequency for the treatment of Barrett's esophagus with and without dysplasia. Multiple modalities are available for topical ablation of the esophagus, but radiofrequency ablation (RFA) remains the most commonly used. There have been significant advances in techniq...

journal_title：BioMed research international

authors： Tuttle R,Nurkin SJ,Hochwald SN

更新日期：2014-01-01 00:00:00

abstract：:Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 an...

journal_title：BioMed research international

authors： Rzepka R,Dołęgowska B,Rajewska A,Sałata D,Budkowska M,Kwiatkowski S,Torbé A

更新日期：2016-01-01 00:00:00

abstract：:The proper functioning of a hospital computer system is an arduous work for managers and staff. However, inconsistent policies are frequent and can produce enormous problems, such as stolen information, frequent failures, and loss of the entire or part of the hospital data. This paper presents a new method named EMRlo...

journal_title：BioMed research international

authors： Martínez Monterrubio SM,Frausto Solis J,Monroy Borja R

更新日期：2015-01-01 00:00:00

abstract：:Three-dimensional (3D) liver tumor segmentation from Computed Tomography (CT) images is a prerequisite for computer-aided diagnosis, treatment planning, and monitoring of liver cancer. Despite many years of research, 3D liver tumor segmentation remains a challenging task. In this paper, an efficient semiautomatic meth...

journal_title：BioMed research international

authors： Wu W,Wu S,Zhou Z,Zhang R,Zhang Y

更新日期：2017-01-01 00:00:00

abstract：:We previously reported that Runx2/miR-3960/miR-2861 regulatory feedback loop stimulates osteoblast differentiation. However, the effect of this feedback loop on the osteogenic transdifferentiation of vascular smooth muscle cells (VSMCs) remains unclear. Our recent study showed that miR-2861 and miR-3960 expression inc...

journal_title：BioMed research international

authors： Xia ZY,Hu Y,Xie PL,Tang SY,Luo XH,Liao EY,Chen F,Xie H

更新日期：2015-01-01 00:00:00

abstract：:Insecticide resistance in malaria vectors threatens malaria prevention and control efforts. In Colombia the three primary vectors, Anopheles darlingi, An. nuneztovari s.l., and An. albimanus, have reported insecticide resistance to pyrethroids, organophosphates, carbamates, and DDT; however, the insecticide resistance...

journal_title：BioMed research international

authors： Orjuela LI,Morales JA,Ahumada ML,Rios JF,González JJ,Yañez J,Rosales A,Cabarcas DM,Venegas J,Yasnot MF,Quiñones ML

更新日期：2018-08-29 00:00:00

abstract：:Heteronemin is a bioactive marine sesterterpene isolated from the sponge Hyrtios sp. Previous reports have shown that heteronemin possesses anticancer activity. Here, heteronemin displayed cytotoxic effects against three human cancer cell lines (A549, ACHN, and A498) and exhibited potent activity in A498 human renal c...

journal_title：BioMed research international

authors： Wu SY,Sung PJ,Chang YL,Pan SL,Teng CM

更新日期：2015-01-01 00:00:00

abstract：:Diabetic foot ulcers (DFUs) are characterized by an unsatisfactory inflammatory and migratory response. Skin inflammation involves the participation of many cells and particularly macrophages. Macrophage function can be modulated by neuropeptides; however, little is known regarding the role of neurotensin (NT) as a mo...

journal_title：BioMed research international

authors： Moura LI,Silva L,Leal EC,Tellechea A,Cruz MT,Carvalho E

更新日期：2013-01-01 00:00:00

abstract：:Lung illness encountered in patients with rheumatic diseases bears clinical significance in terms of increased morbidity and mortality as well as potential challenges placed on patient care. Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accum...

journal_title：BioMed research international

authors： Ha YJ,Lee YJ,Kang EH

更新日期：2018-05-08 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to investigate the potential of microparticles based on biocompatible phytolipids [Softisan® 154 (SF) (hydrogenated palm oil) and super-refined sunseed oil (SO)] and polyethylene glycol- (PEG-) 4000 to improve intravaginal delivery of miconazole nitrate (MN) for effective treatment of vulvova...

journal_title：BioMed research international

authors： Kenechukwu FC,Attama AA,Ibezim EC,Nnamani PO,Umeyor CE,Uronnachi EM,Momoh MA,Akpa PA,Ozioko AC

更新日期：2018-06-06 00:00:00

abstract：:A wide range of molecular techniques have been developed for genotyping Candida species. Among them, multilocus sequence typing (MLST) and microsatellite length polymorphisms (MLP) analysis have recently emerged. MLST relies on DNA sequences of internal regions of various independent housekeeping genes, while MLP iden...

journal_title：BioMed research international

authors： Spampinato C,Leonardi D

更新日期：2013-01-01 00:00:00

abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

journal_title：BioMed research international

authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

更新日期：2020-09-09 00:00:00

abstract：:In this paper, differences between multichannel EEG signals of artists and nonartists were analyzed during visual perception and mental imagery of some paintings and at resting condition using approximate entropy (ApEn). It was found that ApEn is significantly higher for artists during the visual perception and the me...

journal_title：BioMed research international

authors： Shourie N,Firoozabadi M,Badie K

更新日期：2014-01-01 00:00:00

abstract：Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...

journal_title：BioMed research international

authors： Zhou J,Xie Z,Cui P,Su Q,Zhang Y,Luo L,Li Z,Ye L,Liang H,Huang J

更新日期：2020-05-23 00:00:00

abstract：:Autophagic elements typically appear as spherical bodies. During their life they undergo a series of changes (e.g., fusion, degradation of content, and swelling) which influence their size in a way that may be characteristic for cell type, stage of maturation, or various experimentally manipulated parameters. A simple...

journal_title：BioMed research international

authors： Kovács AL

更新日期：2014-01-01 00:00:00

abstract：Background:Long noncoding RNAs (lncRNAs) play a crucial role in varieties of biological processes. This study is aimed at investigating meniscal degeneration-specific lncRNAs and mRNAs and their related networks in knee osteoarthritis (KOA). Methods:The dataset GSE98918, which included 24 meniscus samples and related ...

journal_title：BioMed research international

authors： Zhao J,Su Y,Jiao J,Wang Z,Fang X,He X,Zhang X,Liu Z,Xu X

更新日期：2020-05-20 00:00:00

abstract：:Postoperative surgical site infections (SSIs) are more common complications after spinal surgery. SSIs often require extended hospitalisation and may worsen overall clinical outcomes. A retrospective database review of consecutive patients with traditional open lumbar spinal surgery was performed. SSIs patients were i...

journal_title：BioMed research international

authors： Liu JT,Liao WJ,Chang CS,Chen YH

更新日期：2015-01-01 00:00:00

abstract：:High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...

journal_title：BioMed research international

authors： Mardente S,Mari E,Massimi I,Fico F,Faggioni A,Pulcinelli F,Antonaci A,Zicari A

更新日期：2015-01-01 00:00:00

abstract：Background:As a newly discovered lncRNA, bladder cancer-associated transcript 1 (BLACAT1) has been reported to correlate with poor clinical outcomes in several different cancers. This study aimed to evaluate its generalized predictive value for cancer prognosis. Materials and Methods:We thoroughly searched PubMed, Emb...

journal_title：BioMed research international

authors： Lu H,Liu H,Yang X,Ye T,Lv P,Wu X,Ye Z

更新日期：2019-04-02 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2013/783690.]. ...

journal_title：BioMed research international

authors： Ebrahimi Nigjeh S,Yusoff FM,Alitheen NB,Pirozyan MR,Keong YS,Omar AR

更新日期：2016-01-01 00:00:00

abstract：:Insecticides are still largely applied in public health to control disease vectors. In Brazil, organophosphates (OP) and pyrethroids (PY) are used against Aedes aegypti for years. Since 2009 Insect Growth Regulators (IGR) are also employed in the control of larvae. We quantified resistance to temephos (OP), deltamethr...

journal_title：BioMed research international

authors： Bellinato DF,Viana-Medeiros PF,Araújo SC,Martins AJ,Lima JB,Valle D

更新日期：2016-01-01 00:00:00

abstract：:Molecular recognition elements (MREs) can be short sequences of single-stranded DNA, RNA, small peptides, or antibody fragments. They can bind to user-defined targets with high affinity and specificity. There has been an increasing interest in the identification and application of nucleic acid molecular recognition el...

journal_title：BioMed research international

authors： Hong KL,Sooter LJ

更新日期：2015-01-01 00:00:00