Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions.

abstract：:To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...

journal_title：BioMed research international

authors： Hu S,Liao Y,Zheng J,Gou L,Regmi A,Zafar MI,Chen L

更新日期：2019-03-28 00:00:00

abstract：Background:There is little data available on HBV infection and mother-to-child transmission (MTCT) in Vietnam. Objective:This study is aimed at assessing the prevalence of HBV infection and the current situation of MTCT in Haiphong, Vietnam. Methods:A transversal survey of 1721 pregnant women followed by an observati...

journal_title：BioMed research international

authors： Khue PM,Thuy Linh NT,Vinh VH,Dung LV,Nguyen Van B

更新日期：2020-08-20 00:00:00

abstract：:India is highly endemic to malaria with prevalence of all five species of human malaria parasites of Plasmodium genus. India is set for malaria elimination by 2030. Since cases of mixed Plasmodium species infections remain usually undetected but cause huge disease burden, in order to understand the distributional prev...

journal_title：BioMed research international

authors： Singh US,Siwal N,Pande V,Das A

更新日期：2017-01-01 00:00:00

abstract：:Artery calcification is a well-recognized predictor of late atherosclerotic complications. In the intima media, calcification starts with apoptosis of vascular smooth muscle cells (VSMCs) and the release of calcifying matrix vesicles with diameter of 0.5-15 μm that can be observed microscopically. In complicated plaqu...

journal_title：BioMed research international

authors： Chistiakov DA,Myasoedova VA,Melnichenko AA,Grechko AV,Orekhov AN

更新日期：2017-01-01 00:00:00

abstract：:This paper describes a pilot study using a prototype telerehabilitation system (Ghostman). Ghostman is a visual augmentation system designed to allow a physical therapist and patient to inhabit each other's viewpoint in an augmented real-world environment. This allows the therapist to deliver instruction remotely and ...

journal_title：BioMed research international

authors： Chinthammit W,Merritt T,Pedersen S,Williams A,Visentin D,Rowe R,Furness T

更新日期：2014-01-01 00:00:00

abstract：:This paper reports the results of an ethnobotanical survey on the use of medicinal plants by community healers "Hampiyachakkuna" in the San Lucas Parish, province of Loja, Ecuador. A particular ethnic group, the indigenous Saraguros, inhabits this region. This study reports 183 plant species used in 75 different curat...

journal_title：BioMed research international

authors： Andrade JM,Lucero Mosquera H,Armijos C

更新日期：2017-01-01 00:00:00

abstract：Purpose:Ischemic ocular disorders may be treated by hypervolemic hemodilution. The presumed therapeutic benefit is based on a volume effect and improved rheological factors. The aim was to investigate the acute effect of intravenous hydroxyethyl starch on retrobulbar hemodynamics in patients with nonarteritic anterior ...

journal_title：BioMed research international

authors： Bienert M,Plange N,Remky A,Arend KO,Kuerten D

更新日期：2018-02-06 00:00:00

abstract：:Several lines of evidence indicate that amyloid β (Aβ), particularly Aβ oligomers (AβOs), plays a causative role in Alzheimer's disease. However, the mechanisms underlying the action of an anti-AβO antibody to clarify the toxic action of AβOs remain elusive. Here, we showed that the anti-AβO antibody (monoclonal 72D9)...

journal_title：BioMed research international

authors： Matsubara E,Takamura A,Okamoto Y,Oono H,Nakata T,Wakasaya Y,Kawarabayashi T,Shoji M

更新日期：2013-01-01 00:00:00

abstract：Introduction:We investigated the proportion of myeloid-derived suppressor cells (MDSCs) and their subsets in patients with rheumatic diseases and clarified the association between these cells and the patient clinical data. Methods:Patients with rheumatic diseases and healthy controls were recruited. The clinical chara...

journal_title：BioMed research international

authors： Zhu J,Chen S,Wu L,Wang R,Zheng S,Zhao D,Wang X,Li J

更新日期：2018-06-26 00:00:00

abstract：:Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin-2 (Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of this study was to introduce a computational simulation approach to screen aptamers with high binding ability for Ang2. We carried out...

journal_title：BioMed research international

authors： Hu WP,Kumar JV,Huang CJ,Chen WY

更新日期：2015-01-01 00:00:00

abstract：:Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC pr...

journal_title：BioMed research international

authors： Lahner M,Ull C,Hagen M,von Schulze Pellengahr C,Daniilidis K,von Engelhardt LV,Lahner N,Teske W

更新日期：2018-05-08 00:00:00

abstract：:The aim of this study was to evaluate a novel composite material for tracheal reconstruction in an ovine model. A polymer containing various forms of carbon fibers (roving, woven, and nonwoven fabric) impregnated with polysulfone (PSU) was used to create cylindrical tracheal implants, 3 cm in length and 2.5 cm in diam...

journal_title：BioMed research international

authors： Ścierski W,Lisowska G,Namysłowski G,Misiołek M,Pilch J,Menaszek E,Gawlik R,Błażewicz M

更新日期：2018-10-17 00:00:00

abstract：Background:Fibroid is the most common benign tumor of the uterus and if associated with pregnancy may adversely affect the outcome of pregnancy. Objective of the present study was to assess the obstetric outcome (maternal and fetal) in pregnancy with fibroid. Methods:A prospective observational study was performed ove...

journal_title：BioMed research international

authors： Saleh HS,Mowafy HE,Hameid AAAE,Sherif HE,Mahfouz EM

更新日期：2018-03-26 00:00:00

abstract：:Protein phosphorylation is catalyzed by kinases which regulate many aspects that control death, movement, and cell growth. Identification of the phosphorylation site-specific kinase-substrate relationships (ssKSRs) is important for understanding cellular dynamics and provides a fundamental basis for further disease-re...

journal_title：BioMed research international

authors： Wang M,Wang T,Wang B,Liu Y,Li A

更新日期：2017-01-01 00:00:00

abstract：:Objective. To confirm that physical activity program improves the symptoms of dementia and the most effective physical activity was selected to help establish exercise programs. Methods. Three databases, PubMed, Science Direct, and Willey online, were used to collect articles. The databases were published between Janu...

journal_title：BioMed research international

authors： Lee HS,Park SW,Park YJ

更新日期：2016-01-01 00:00:00

abstract：:Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus, simulating stomach and small intestine. A universal dissolution method was employed which simulated the physiology of human gastrointestinal tract, including the precis...

journal_title：BioMed research international

authors： Čulen M,Tuszyński PK,Polak S,Jachowicz R,Mendyk A,Dohnal J

更新日期：2015-01-01 00:00:00

abstract：:Salinity is a major environmental stress that limits crop production worldwide. In this study, we characterized plant growth-promoting rhizobacteria (PGPR) containing 1-aminocyclopropane-1-carboxylate (ACC) deaminase and examined their effect on salinity stress tolerance in okra through the induction of ROS-scavenging...

journal_title：BioMed research international

authors： Habib SH,Kausar H,Saud HM

更新日期：2016-01-01 00:00:00

abstract：:Multiparametric MRI of the prostate combines high-resolution anatomic imaging with functional imaging of alterations in normal tissue caused by neoplastic transformation for the identification and characterization of in situ prostate cancer. Lesion detection relies on a systematic approach to the analysis of both anat...

journal_title：BioMed research international

authors： Margolis DJ

更新日期：2014-01-01 00:00:00

abstract：:Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...

journal_title：BioMed research international

authors： Léonard B,Kridelka F,Delbecque K,Goffin F,Demoulin S,Doyen J,Delvenne P

更新日期：2014-01-01 00:00:00

abstract：:We recruited a group of 6713 consecutive Chinese patients with T2D but normal renal and liver function who were admitted to one of 81 top tertiary care hospitals in China. Mild hypoglycaemia was defined as having symptomatic hypoglycaemia in one month before hospitalization. Severe hypoglycaemia was defined as having ...

journal_title：BioMed research international

authors： Li Y,Mu Y,Ji Q,Huang Q,Kuang H,Ji L,Yang X

更新日期：2015-01-01 00:00:00

abstract：Background:The aim of this study was to assess changes in skin microbiota of wrestlers during training sessions and to determine the sensitivity of hemolytic bacterial isolates to antiseptics. Methods:The main skin bacterial isolates obtained from the skin of 15 wrestlers were identified by cultivation method, with th...

journal_title：BioMed research international

authors： Martykanova DS,Davletova NC,Zemlenuhin IA,Volchkova VI,Mugallimov SM,Ahatov AM,Laikov AV,Markelova MI,Boulygina EA,Lopukhov LV,Grigoryeva TV

更新日期：2019-01-10 00:00:00

abstract：:Objective. To evaluate the association of -174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican-Mestizo patients with moderate or severe rheumatoid arthritis (RA), initiating MTX or LEF, genotyped for IL-6 -...

journal_title：BioMed research international

authors： Ruiz-Padilla AJ,Gamez-Nava JI,Saldaña-Cruz AM,Murillo-Vazquez JD,Vazquez-Villegas ML,Zavaleta-Muñiz SA,Martín-Márquez BT,Ponce-Guarneros JM,Rodriguez Jimenez NA,Flores-Chavez A,Sandoval-Garcia F,Vasquez-Jimenez JC,Cardona-Muñoz E

更新日期：2016-01-01 00:00:00

abstract：:To investigate white matter (WM) abnormalities in neocortical epilepsy, we extract supratentorial WM parameters from raw tensor magnetic resonance images (MRI) with automated region-of-interest (ROI) registrations. Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched...

journal_title：BioMed research international

authors： Peng SJ,Harnod T,Tsai JZ,Huang CC,Ker MD,Chiou JC,Chiueh H,Wu CY,Hsin YL

更新日期：2014-01-01 00:00:00

abstract：:A large body of evidence has emerged over the past years to show the critical role played by inflammation in the pathogenesis of several diseases including some cardiovascular, neoplastic, and neurodegenerative diseases, previously not considered inflammation-related. The anti-inflammatory action of ω-3 polyunsaturate...

journal_title：BioMed research international

authors： Calviello G,Su HM,Weylandt KH,Fasano E,Serini S,Cittadini A

更新日期：2013-01-01 00:00:00

abstract：:Hydrogel injection has been recently proposed as a novel therapy for disc degenerative diseases, with the potential to restore the spine motion and the intervertebral disc height. However, it remains unknown whether the new technique could also maintain the shock absorbing property of the treated intervertebral disc. ...

journal_title：BioMed research international

authors： Zhou Z,Gao M,Wei F,Liang J,Deng W,Dai X,Zhou G,Zou X

更新日期：2014-01-01 00:00:00

abstract：:Q192R and L55M polymorphism were considered to be associated with the development of multiple cancers. Nevertheless, the results of these researches were inconclusive and controversial. Therefore, we conducted a meta-analysis of all eligible case-control studies to assess the association between PON1 (Q192R and L55M) ...

journal_title：BioMed research international

authors： Pan X,Huang L,Li M,Mo D,Liang Y,Liu Z,Huang Z,Huang L,Liu J,Zhu B

更新日期：2019-07-28 00:00:00

abstract：:The increased use of imaging modalities in the last years has led to a greater incidence in depicting abdominal incidental lesions. In particular, "incidentalomas" of the kidney are discovered in asymptomatic patients or patients who suffer from diseases not directly related to the kidneys. The aim of this paper is to...

journal_title：BioMed research international

authors： Mazziotti S,Cicero G,D'Angelo T,Marino MA,Visalli C,Salamone I,Ascenti G,Blandino A

更新日期：2017-01-01 00:00:00

abstract：Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...

journal_title：BioMed research international

authors： Liu H,Zhang Y,Sun S,Wang S

更新日期：2019-07-17 00:00:00

abstract：OBJECTIVE:Fever in systemic lupus erythematosus (SLE) can be caused by infection or flare-up of the disease. This study aimed to determine whether the ratio of the level of erythrocyte-bound C4d to that of complement receptor 1 (C4d/CR1) can serve as a useful biomarker in the differentiation between infection and flare...

journal_title：BioMed research international

authors： Chen CH,Tai SB,Chen HC,Yang DH,Peng MY,Lin YF

更新日期：2015-01-01 00:00:00

abstract：:N6-methyladenosine (m6A) plays an important role in many cancers. However, few studies have examined the role of m6A in colorectal CRC. To examine the effect of m6A on CRC, we studied the genome of 591 CRC cases from The Cancer Genome Atlas (TCGA). The relationship between the messenger RNA (mRNA) expression, copy num...

journal_title：BioMed research international

authors： Zhang Q,Cai Y,Kurbatov V,Khan SA,Lu L,Zhang Y,Johnson CH

更新日期：2020-12-19 00:00:00