The -174G/C Interleukin-6 Gene Promoter Polymorphism as a Genetic Marker of Differences in Therapeutic Response to Methotrexate and Leflunomide in Rheumatoid Arthritis.

abstract：:Objectives. The aim of the study is to detect the prevalence and the characteristics of infraorbital canal and Haller's cells on panoramic radiography of edentulous patients. Methods. The study group comprised 291 panoramic radiographs of edentulous patients. Radiographs were interpreted for the visibility and charact...

journal_title：BioMed research international

authors： Yesilova E,Bayrakdar IS

更新日期：2018-07-08 00:00:00

abstract：:Adverse perinatal outcomes in singleton IVF pregnancies have been most often explained by parental underlying diseases and so far laboratory conditions during embryo culture are still not explored well. The following review discusses the current state of knowledge on the influence of IVF laboratory procedures on the p...

journal_title：BioMed research international

authors： Marianowski P,Dąbrowski FA,Zyguła A,Wielgoś M,Szymusik I

更新日期：2016-01-01 00:00:00

abstract：Objectives:The mortality rate of patients with acute respiratory distress syndrome (ARDS) is high. Hence, it is crucial to identify a reliable biomarker with wide clinical applications for predicting the prognosis of patients with ARDS. This systematic review and meta-analysis was conducted to investigate the value of ...

journal_title：BioMed research international

authors： Ni Q,Li C,Lin H

更新日期：2020-04-05 00:00:00

abstract：:The research was performed on male Wistar rats based on assumptions that new microelement preparations containing metal nanoparticles and their agglomerates had potential. Morphological and functional changes in tissues in the injection site and dynamics of chemical element metabolism (25 indicators) in body were asse...

journal_title：BioMed research international

authors： Sizova E,Miroshnikov S,Yausheva E,Polyakova V

更新日期：2015-01-01 00:00:00

abstract：:In the present work we developed a MPN quantitative real-time PCR (MPN-qPCR) method for a fast and reliable detection and quantification of Listeria monocytogenes and Escherichia coli O157:H7 in minimally processed vegetables. In order to validate the proposed technique, the results were compared with conventional MPN...

journal_title：BioMed research international

authors： Russo P,Botticella G,Capozzi V,Massa S,Spano G,Beneduce L

更新日期：2014-01-01 00:00:00

abstract：:Molecular recognition elements (MREs) can be short sequences of single-stranded DNA, RNA, small peptides, or antibody fragments. They can bind to user-defined targets with high affinity and specificity. There has been an increasing interest in the identification and application of nucleic acid molecular recognition el...

journal_title：BioMed research international

authors： Hong KL,Sooter LJ

更新日期：2015-01-01 00:00:00

abstract：:Autophagy is involved in the development of numerous illnesses, including ischemia/reperfusion (I/R). Endothelial nitric oxide synthase (eNOS) participates in the protective effects of ischemic postconditioning (IPostC). However, it remains unclear whether eNOS-mediated autophagy serves as a critical role in IPostC in...

journal_title：BioMed research international

authors： Shao J,Miao C,Geng Z,Gu M,Wu Y,Li Q

更新日期：2019-02-10 00:00:00

abstract：:Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...

journal_title：BioMed research international

authors： Tan BL,Norhaizan ME

更新日期：2017-01-01 00:00:00

abstract：:A novel approach for selecting a rectangular template around periocular region optimally potential for human recognition is proposed. A comparatively larger template of periocular image than the optimal one can be slightly more potent for recognition, but the larger template heavily slows down the biometric system by ...

journal_title：BioMed research international

authors： Bakshi S,Sa PK,Majhi B

更新日期：2013-01-01 00:00:00

abstract：:We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear probes (C- or padlock ...

journal_title：BioMed research international

authors： Smith JH,Cui M,Zhang DY,Beals TP,Ye F

更新日期：2014-01-01 00:00:00

abstract：:Hosts' innate defense systems are upregulated by antimicrobial peptide elicitors (APEs). Our aim was to investigate the effects of hyperthermia, ultraviolet A rays (UVA), and ultraviolet C rays (UVC) as well as glucose and ascorbic acid (AA) on the regulation of human β-defensin 1 (DEFB1), cathelicidin (CAMP), and int...

journal_title：BioMed research international

authors： Cruz Díaz LA,Flores Miramontes MG,Chávez Hurtado P,Allen K,Gonzalez Ávila M,Prado Montes de Oca E

更新日期：2015-01-01 00:00:00

abstract：:In the biomedical field, there is growing interest in using human stem cell-derived neurons as in vitro models for pharmacological and toxicological screening of bioactive compounds extracted from natural products. Lignosus rhinocerus (Tiger Milk Mushroom) is used by indigenous communities in Malaysia as a traditional...

journal_title：BioMed research international

authors： Yeo Y,Tan JBL,Lim LW,Tan KO,Heng BC,Lim WL

更新日期：2019-08-19 00:00:00

abstract：:Diverse high energy diets have been utilized to precipitate obesity and related metabolic disorders in rodent models, though the dietary intervention has not absolutely been standardized. The present study established usage of a customized semipurified normal control diet (NCD) and high fat diet (HFD), for research st...

journal_title：BioMed research international

authors： Sasidharan SR,Joseph JA,Anandakumar S,Venkatesan V,Ariyattu Madhavan CN,Agarwal A

更新日期：2013-01-01 00:00:00

abstract：:The administration of probiotic bacteria for health benefit has rapidly expanded in recent years, with a global market worth $32.6 billion predicted by 2014. The oral administration of most of the probiotics results in the lack of ability to survive in a high proportion of the harsh conditions of acidity and bile conc...

journal_title：BioMed research international

authors： Solanki HK,Pawar DD,Shah DA,Prajapati VD,Jani GK,Mulla AM,Thakar PM

更新日期：2013-01-01 00:00:00

abstract：Background:The aim of this study was to assess changes in skin microbiota of wrestlers during training sessions and to determine the sensitivity of hemolytic bacterial isolates to antiseptics. Methods:The main skin bacterial isolates obtained from the skin of 15 wrestlers were identified by cultivation method, with th...

journal_title：BioMed research international

authors： Martykanova DS,Davletova NC,Zemlenuhin IA,Volchkova VI,Mugallimov SM,Ahatov AM,Laikov AV,Markelova MI,Boulygina EA,Lopukhov LV,Grigoryeva TV

更新日期：2019-01-10 00:00:00

abstract：:Copy number variants (CNVs) as detected by chromosomal microarray analysis (CMA) significantly contribute to the etiology of neurodevelopmental disorders, such as developmental delay (DD), intellectual disability (ID), and autism spectrum disorder (ASD). This study summarizes the results of 3.5 years of CMA testing by...

journal_title：BioMed research international

authors： Ho KS,Twede H,Vanzo R,Harward E,Hensel CH,Martin MM,Page S,Peiffer A,Mowery-Rushton P,Serrano M,Wassman ER

更新日期：2016-01-01 00:00:00

abstract：:Stressful events can have both short- and long-term effects on the brain. Our recent investigation identified short-term white matter integrity (WMI) changes in 30 subjects soon after the Japanese earthquake. Our findings suggested that lower WMI in the right anterior cingulum (Cg) was a pre-existing vulnerability fac...

journal_title：BioMed research international

authors： Sekiguchi A,Kotozaki Y,Sugiura M,Nouchi R,Takeuchi H,Hanawa S,Nakagawa S,Miyauchi CM,Araki T,Sakuma A,Taki Y,Kawashima R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To analyze the clinical relevance of the levels of TNFα blockers and anti-drug antibodies (anti-drug Ab) in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA) treated with adalimumab (ADA), etanercept (ETA), or infliximab (INF) for a prolonged period of time. METHODS:Clinical characteristics...

journal_title：BioMed research international

authors： Arstikyte I,Kapleryte G,Butrimiene I,Venalis A

更新日期：2015-01-01 00:00:00

abstract：:TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dynamics simulations ...

journal_title：BioMed research international

authors： Wan H,Chang S,Hu JP,Tian XH,Wang MH

更新日期：2016-01-01 00:00:00

abstract：:Studies on the occurrence of pharmaceuticals show that the widely used pharmaceuticals ibuprofen and diclofenac are present in relevant concentrations in the environment. A pilot plant treating hospital wastewater with relevant concentrations of these pharmaceuticals was evaluated for its performance to reduce the con...

journal_title：BioMed research international

authors： Langenhoff A,Inderfurth N,Veuskens T,Schraa G,Blokland M,Kujawa-Roeleveld K,Rijnaarts H

更新日期：2013-01-01 00:00:00

abstract：:Biolasol is a newly developed solution for storing the liver, pancreas, kidneys, and heart by simple hypothermia. It exhibits high efficacy in maintaining structural and functional integrity of the graft prior to its transplantation. The solution was modified by the addition of ascorbic acid (0.088g/l) and ascorbic ac...

journal_title：BioMed research international

authors： Ostróżka-Cieślik A,Dolińska B,Ryszka F

更新日期：2018-11-12 00:00:00

abstract：:Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF). Hitherto, the development of consistent, stable, and reproducible models of closed-chest MI in large animals, ...

journal_title：BioMed research international

authors： Biondi-Zoccai G,De Falco E,Peruzzi M,Cavarretta E,Mancone M,Leoni O,Caristo ME,Lotrionte M,Marullo AG,Amodeo A,Pacini L,Calogero A,Petrozza V,Chimenti I,D'Ascenzo F,Frati G

更新日期：2013-01-01 00:00:00

abstract：:The increasing insect resistance against Bacillus thuringiensis delta-endotoxins is a serious problem which makes it urgent to look for new eco-friendly strategies. Combining these toxins with other biomolecules is one of the promising strategies against insect pests. In this work, we evaluated the bioinsecticidal pot...

journal_title：BioMed research international

authors： Mhalla D,Ben Farhat-Touzri D,Tounsi S,Trigui M

更新日期：2018-08-08 00:00:00

abstract：:Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent a modern approach for management of chronic skin injuries. In this work, we describe BM-MSCs application versus their conditioned media (CM) when delivered topically admixed with fibrin glue to enhance the healing of chronic excisional wounds in rats. Fift...

journal_title：BioMed research international

authors： Mehanna RA,Nabil I,Attia N,Bary AA,Razek KA,Ahmed TA,Elsayed F

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To investigate the correlation of outer retinal layers (ORL) thickness and visual acuity (VA) in patients with diabetic macular edema (DME). METHODS:Consecutive DME patients seen at the Retina Clinic of The University of Hong Kong were recruited for OCT assessment. The ORL thickness was defined as the distance...

journal_title：BioMed research international

authors： Wong RL,Lee JW,Yau GS,Wong IY

更新日期：2015-01-01 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：:Craniofacial development consists of a highly complex sequence of the orchestrated growth and fusion of facial processes. It is also known that craniofacial abnormalities can be detected in 1/3 of all patients with congenital diseases. Within the various craniofacial abnormalities, orofacial clefting is one of the mos...

journal_title：BioMed research international

authors： Kurosaka H

更新日期：2015-01-01 00:00:00

abstract：:Gastric cancer is one of the most common cancers and the efficient therapeutic methods are limited. Further study of the exact molecular mechanism of gastric cancer to develop novel targeted therapies is necessary and urgent. We herein systematically examined that miR-204 suppressed both proliferation and metastasis o...

journal_title：BioMed research international

authors： Yuan X,Wang S,Liu M,Lu Z,Zhan Y,Wang W,Xu AM

更新日期：2017-01-01 00:00:00

abstract：:Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is a complex multifactorial process. Animal models are essential to furthering understanding of the degenerative process and testing pot...

journal_title：BioMed research international

authors： Daly C,Ghosh P,Jenkin G,Oehme D,Goldschlager T

更新日期：2016-01-01 00:00:00

abstract：:Mixed-phase TiO2 nanocomposite thin films consisting of anatase and rutile prepared on commercially pure Ti sheets via the electrochemical anodization and annealing treatments were investigated in terms of their photocatalytic activity for antibacterial use around dental implants. The resulting films were characterize...

journal_title：BioMed research international

authors： Yeniyol S,Mutlu I,He Z,Yüksel B,Boylan RJ,Ürgen M,Karabuda ZC,Basegmez C,Ricci JL

更新日期：2015-01-01 00:00:00