Gene Alterations of N6-Methyladenosine (m6A) Regulators in Colorectal Cancer: A TCGA Database Study.

abstract：:The search for effective methods of myocardial cytoprotection against ischemia is the most significant issue in modern cardiology and cardiac surgery. Glucocorticoids are deemed very strong modulators of inflammatory response and thus can potentially protect heart muscle from postreperfusion injury and myocardial isch...

journal_title：BioMed research international

authors： Kuropka P,Dobrzyński M,Gamian A,Gostomska-Pampuch K,Kuryszko J,Całkosiński I

更新日期：2017-01-01 00:00:00

abstract：:Bioarcheology is cross disciplinary research encompassing the study of human remains. However, life's activities have, up till now, eluded bioarcheological investigation. We hypothesized that growth lines in hair might archive the biologic rhythms, growth rate, and metabolism during life. Computational modeling predic...

journal_title：BioMed research international

authors： Qualls C,Bianucci R,Spilde MN,Phillips G,Wu C,Appenzeller O

更新日期：2015-01-01 00:00:00

abstract：:Osteoarthritis (OA) is one of the most common debilitating disorders among the elderly population. At present, there is no definite cure for the underlying causes of OA. However, adipose tissue-derived stem cells (ADSCs) in the form of stromal vascular fraction (SVF) may offer an alternative at this time. ADSCs are on...

journal_title：BioMed research international

authors： Pak J,Lee JH,Kartolo WA,Lee SH

更新日期：2016-01-01 00:00:00

abstract：:In orthopaedic surgery and sports medicine, the knee joint has traditionally been considered the workhorse. The reconstruction of every damaged element in this joint is crucial in achieving the surgeon's goal to restore the knee function and prevent degeneration towards osteoarthritis. In the last fifteen years, the f...

journal_title：BioMed research international

authors： Sánchez M,Delgado D,Sánchez P,Fiz N,Azofra J,Orive G,Anitua E,Padilla S

更新日期：2014-01-01 00:00:00

abstract：Background:This study explored the therapeutic efficacy of standard triple therapy combined with sucralfate suspension gel as well as the mechanisms of action in mouse models of H. pylori infection. Materials and Methods:C57BL/6J mice were randomly divided into 5 groups: NC (natural control), HP (H. pylori infection),...

journal_title：BioMed research international

authors： Teng G,Liu Y,Wu T,Wang W,Wang H,Hu F

更新日期：2020-08-31 00:00:00

abstract：:To explore the antitumor effect of hypoxia-inducible factor-1α short hairpin RNA (HIF-1α shRNA) delivered by ultrasound targeted microbubble destruction (UTMD) and transcatheter arterial embolization (TAE) on rats with hepatic cancer. After the models of transplantation hepatoma were established, Wistar rats were rand...

journal_title：BioMed research international

authors： Liao Y,Luo H,He Z,Kuang Y,Chen P,Zhang X,Chen J,Wen Q,Xie Y,Ding S

更新日期：2019-02-19 00:00:00

abstract：:Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs and polymorphisms in ...

journal_title：BioMed research international

authors： García-Bermúdez M,López-Mejías R,Genre F,Castañeda S,Corrales A,Llorca J,González-Juanatey C,Ubilla B,Miranda-Filloy JA,Pina T,Gómez-Vaquero C,Rodríguez-Rodríguez L,Fernández-Gutiérrez B,Balsa A,Pascual-Salcedo D,López-Long

更新日期：2015-01-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer death worldwide. Adenocarcinoma, the most commonly diagnosed histologic type of lung cancer, is associated with smoking. Cigarette smoke promotes inflammation on the airways, which might be mediated by Th17 cells. This inflammatory environment may contribute to tumor developm...

journal_title：BioMed research international

authors： Islas-Vazquez L,Prado-Garcia H,Aguilar-Cazares D,Meneses-Flores M,Galicia-Velasco M,Romero-Garcia S,Camacho-Mendoza C,Lopez-Gonzalez JS

更新日期：2015-01-01 00:00:00

abstract：:Heavy metals have the potential to interact and induce several stress responses in the plants; thus, effects of heavy metal stress on DNA damages and total antioxidants level in Urtica dioica leaves and stems were investigated. The samples are sampled from areas with different metal exposition. Metal content was analy...

journal_title：BioMed research international

authors： Gjorgieva D,Kadifkova Panovska T,Ruskovska T,Bačeva K,Stafilov T

更新日期：2013-01-01 00:00:00

abstract：:Schistosomiasis is one of the world's major public health problems. Praziquantel is currently the only effective drug against schistosomiasis. As resistance of praziquantel has emerged in some endemic areas, development of new antischistosomal agents should be a high priority. In this study, a phage display peptide li...

journal_title：BioMed research international

authors： Song LJ,Li JH,Yin XR,Zhang W,Jin Y,Gao H,Wang J,Yu CX,Hua ZC

更新日期：2018-06-05 00:00:00

abstract：:Modified poly(aspartic acid)/poly(vinyl alcohol) interpenetrating polymer network (KPAsp/PVA IPN) hydrogel for drug controlled release was synthesized by a simple one-step method in aqueous system using poly(aspartic acid) grafting 3-aminopropyltriethoxysilane (KH-550) and poly(vinyl alcohol) (PVA) as materials. The h...

journal_title：BioMed research international

authors： Lu J,Li Y,Hu D,Chen X,Liu Y,Wang L,Zhao Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Tumor patients and patients after traumas are endangered by a reduced immune defense, and a silver coating on their megaprostheses may reduce their risks of infection. The aim of this study was to determine the silver ion concentration directly measured from the periprosthetic tissue and the influence on the...

journal_title：BioMed research international

authors： Hussmann B,Johann I,Kauther MD,Landgraeber S,Jäger M,Lendemans S

更新日期：2013-01-01 00:00:00

abstract：:New antimicrobial properties of products derived from Humulus lupulus L. such as antiadherent and antibiofilm activities were evaluated. The growth of gram-positive but not gram-negative bacteria was inhibited to different extents by these compounds. An extract of hop cones containing 51% xanthohumol was slightly less...

journal_title：BioMed research international

authors： Rozalski M,Micota B,Sadowska B,Stochmal A,Jedrejek D,Wieckowska-Szakiel M,Rozalska B

更新日期：2013-01-01 00:00:00

abstract：:Polyphenolic compounds are plant nutraceuticals showing a huge structural diversity, including chlorogenic acids, hydrolyzable tannins, and flavonoids (flavonols, flavanones, flavan-3-ols, anthocyanidins, isoflavones, and flavones). Most of them occur as glycosylated derivatives in plants and foods. In order to become...

journal_title：BioMed research international

authors： Marín L,Miguélez EM,Villar CJ,Lombó F

更新日期：2015-01-01 00:00:00

abstract：:Malaria is one of the life-threatening diseases in the world. The spread of resistance to antimalarial drugs is a major challenge, and resistance to artemisinin has been reported in the Southeast Asian region. In the previous study, the active compound of Streptomyces hygroscopicus subsp. Hygroscopicus (S. hygroscopic...

journal_title：BioMed research international

authors： Nugraha RY,Faratisha IF,Mardhiyyah K,Ariel DG,Putri FF,Nafisatuzzamrudah,Winarsih S,Sardjono TW,Fitri LE

更新日期：2020-01-09 00:00:00

abstract：:Human plasma is an aqueous solution that has to abide by chemical rules such as the principle of electrical neutrality and the constancy of the ionic product for water. These rules define the acid-base balance in the human body. According to the electroneutrality principle, plasma has to be electrically neutral and th...

journal_title：BioMed research international

authors： Adeva-Andany MM,Carneiro-Freire N,Donapetry-García C,Rañal-Muíño E,López-Pereiro Y

更新日期：2014-01-01 00:00:00

abstract：:Synthetic lethality (SL) is a novel strategy for anticancer therapies, whereby mutations of two genes will kill a cell but mutation of a single gene will not. Therefore, a cancer-specific mutation combined with a drug-induced mutation, if they have SL interactions, will selectively kill cancer cells. While numerous SL...

journal_title：BioMed research international

authors： Li XJ,Mishra SK,Wu M,Zhang F,Zheng J

更新日期：2014-01-01 00:00:00

abstract：:Densitometry data generated for Western blots are commonly used to compare protein abundance between samples. In the last decade, it has become apparent that assumptions underpinning these comparisons are often violated in studies reporting Western blot data in the literature. These violations can lead to erroneous in...

journal_title：BioMed research international

authors： Butler TAJ,Paul JW,Chan EC,Smith R,Tolosa JM

更新日期：2019-01-21 00:00:00

abstract：:A novel approach for selecting a rectangular template around periocular region optimally potential for human recognition is proposed. A comparatively larger template of periocular image than the optimal one can be slightly more potent for recognition, but the larger template heavily slows down the biometric system by ...

journal_title：BioMed research international

authors： Bakshi S,Sa PK,Majhi B

更新日期：2013-01-01 00:00:00

abstract：Background and Aim:The incidence of nonalcoholic fatty liver disease (NAFLD) as a metabolic disease is increasing annually. In the present study, we aimed to explore the influence of NAFLD on the severity of acute pancreatitis (AP). Methods:The severity of AP was diagnosed and analyzed according to the 2012 revised At...

journal_title：BioMed research international

authors： Wu D,Zhang M,Xu S,Wu K,Wang N,Wang Y,Wu J,Lu G,Gong W,Ding Y,Xiao W

更新日期：2019-01-22 00:00:00

abstract：Background:Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies. Considering the recent increase in the prevalence of the family virus and its risk potential, we investigated the codon usage pattern to understand its evolutionar...

journal_title：BioMed research international

authors： Yao H,Chen M,Tang Z

更新日期：2019-06-27 00:00:00

abstract：:Abdominal pregnancy is a very rare form of ectopic pregnancy, associated with high morbidity and mortality for both fetus and mother. It is, and often, seen in poor resource nations, where early diagnosis is often a major challenge due to poor prenatal care and lack of medical resources. An advanced abdominal pregnanc...

journal_title：BioMed research international

authors： Dabiri T,Marroquin GA,Bendek B,Agamasu E,Mikhail M

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2014/169203.]. ...

journal_title：BioMed research international

authors： Arosio B,D'Addario C,Gussago C,Casati M,Tedone E,Ferri E,Nicolini P,Rossi PD,Maccarrone M,Mari D

更新日期：2020-09-07 00:00:00

abstract：Objective:The aim of this study was to investigate the association between adiponectin gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 and environmental risk factors of type 2 diabetes mellitus (T2DM) in Hohhot. The study explored different models of gene-environment interactions, aimed at p...

journal_title：BioMed research international

authors： Cui M,Gao Y,Zhao Y,Pang H,Chen L,Wang Z,Zhao L,Li M

更新日期：2020-06-21 00:00:00

abstract：BACKGROUND:Aquaporin (AQP) 3 and AQP 5 are involved in tumorigenesis and tumor progression of several tumor types. AIM:To investigate expression patterns and clinical significance of AQP3 and AQP5 in hepatocellular carcinoma (HCC). METHODS:Immunohistochemistry was performed to detect the expression of AQP3 and AQP5 i...

journal_title：BioMed research international

authors： Guo X,Sun T,Yang M,Li Z,Li Z,Gao Y

更新日期：2013-01-01 00:00:00

abstract：:Colorectal cancer is the third most common form of cancer in developed countries and, despite the improvements achieved in its treatment options, remains as one of the main causes of cancer-related death. In this review, we first focus on colorectal carcinogenesis and on the genetic and epigenetic alterations involved...

journal_title：BioMed research international

authors： Lizarbe MA,Calle-Espinosa J,Fernández-Lizarbe E,Fernández-Lizarbe S,Robles MÁ,Olmo N,Turnay J

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The vasoconstrictor endothelin-1 (ET-1) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid hemorrhage (SAH). Previous results showed that CGS 26303, an endothelin converting enzyme (ECE) inhibitor, effectively prevented and reversed arterial narrowing in animal m...

journal_title：BioMed research international

authors： Wang CJ,Lee PY,Wu BN,Wu SC,Loh JK,Tsai HP,Chung CL,Kassell NF,Kwan AL

更新日期：2014-01-01 00:00:00

abstract：:As the fifth most common cancer in men and the eighth most common cancer in women, hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, with standard chemotherapy and radiation being minimally effective in prolonging survival. Virus hepatitis, particularly HBV and HCV infection is th...

journal_title：BioMed research international

authors： Wang Z,Jin W,Jin H,Wang X

更新日期：2014-01-01 00:00:00

abstract：:Background. Aortic valve calcification (AVC) is a common feature of aging and is related to coronary artery disease. Although abdominal visceral adipose tissue (VAT) plays fundamental roles in coronary artery disease, the relationship between abdominal VAT and AVC is not fully understood. Methods. We investigated 259 ...

journal_title：BioMed research international

authors： Oikawa M,Owada T,Yamauchi H,Misaka T,Machii H,Yamaki T,Sugimoto K,Kunii H,Nakazato K,Suzuki H,Saitoh S,Takeishi Y

更新日期：2016-01-01 00:00:00

abstract：Aims:To investigate demographics and socioeconomic status in patients with ulnar nerve compression and the influence of socioeconomic factors on patient-reported outcome measurements (PROM) as evaluated by QuickDASH (short version of Disabilities of Arm, Shoulder and Hand) after surgery for ulnar nerve compression at t...

journal_title：BioMed research international

authors： Zimmerman M,Nyman E,Steen Carlsson K,Dahlin LB

更新日期：2020-12-18 00:00:00