In Silico Integration Approach Reveals Key MicroRNAs and Their Target Genes in Follicular Thyroid Carcinoma.

abstract：:A series of amides derived from vanillic acid were obtained by coupling reactions using PyBOP ((Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate) and DCC (Dicyclohexylcarbodiimide) coupling reagents. These were submitted to biological evaluation for species of Candida, Staphylococcus, and Pseudomonas...

journal_title：BioMed research international

authors： Santos Oliveira AJM,de Castro RD,Pessôa HLF,Wadood A,de Sousa DP

更新日期：2019-04-15 00:00:00

abstract：:Platelets are anuclear cells and are devoid of genomic DNA, but they are capable of de novo protein synthesis from mRNA derived from their progenitor cells, megakaryocytes. There is mounting evidence that microRNA (miRNA) plays an important role in regulating gene expression in platelets. miR-223 is the most abundant ...

journal_title：BioMed research international

authors： Shi R,Zhou X,Ji WJ,Zhang YY,Ma YQ,Zhang JQ,Li YM

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to find out the ideal cut-off level of phosphate for safe healing when deformity correction and concomitant lengthening are indicated in the two different skeletal maturity groups of patients with rickets. Thirty-nine hypophosphatemic rickets patients were selected for the study and were divi...

journal_title：BioMed research international

authors： Song SH,Lee H,Jeong JM,Cho WI,Kim SE,Song HR

更新日期：2014-01-01 00:00:00

abstract：:Majority of gram negative pathogenic bacteria are responsible for extended spectrum β-lactamases (ESBLs) production, which show resistance to some newer generation of antibiotics. The study was aimed at evaluating the prevalence of ESBL and antibiotic susceptibility pattern of Pseudomonas isolates collected during 201...

journal_title：BioMed research international

authors： Ahmad M,Hassan M,Khalid A,Tariq I,Asad MH,Samad A,Mahmood Q,Murtaza G

更新日期：2016-01-01 00:00:00

abstract：:The prospect of biomaterial hypersensitivity developing in response to joint implant materials was first presented more than 30 years ago. Many studies have established probable causation between first-generation metal-on-metal hip implants and hypersensitivity reactions. In a limited patient population, implant failu...

journal_title：BioMed research international

authors： Mitchelson AJ,Wilson CJ,Mihalko WM,Grupp TM,Manning BT,Dennis DA,Goodman SB,Tzeng TH,Vasdev S,Saleh KJ

更新日期：2015-01-01 00:00:00

abstract：:Ablative therapies have been utilized with increasing frequency for the treatment of Barrett's esophagus with and without dysplasia. Multiple modalities are available for topical ablation of the esophagus, but radiofrequency ablation (RFA) remains the most commonly used. There have been significant advances in techniq...

journal_title：BioMed research international

authors： Tuttle R,Nurkin SJ,Hochwald SN

更新日期：2014-01-01 00:00:00

abstract：Background:Left ventricular (LV) systolic dysfunction is common in septic shock. Global longitudinal strain (GLS) measured by speckle tracking echocardiography (STE) is a useful marker of intrinsic left ventricular systolic function. However, the association between left ventricular GLS and outcome in septic patients i...

journal_title：BioMed research international

authors： Hai PD,Binh NT,Hien NVQ,Hoang NH,Hoan VN,Son PN,Hoa LTV

更新日期：2020-10-21 00:00:00

abstract：Objective:Study the effect of quality control circle (QCC) in promoting the usage of rubber dams (RD) in root canal treatment of chronic pulpitis in primary teeth. Methods:Set up a quality control group to increase the amount of rubber dams used in the treatment of chronic pulpitis in primary teeth. Monthly monitoring...

journal_title：BioMed research international

authors： Jingxian F,Yang L,Qiong L,Hong Q,Hedi L,Jinglan Z,Fang L,Jing Y,Xiaoming W,Yingying S

更新日期：2020-02-24 00:00:00

abstract：:Sentinel lymph node biopsy (SLNB) emerged in the 1990s as a new technique in the surgical management of the axilla for patients with early breast cancer, resulting in lower complication rates and better quality of life than axillary lymph node dissection (ALND). Today SLNB is firmly established in the armamentarium of...

journal_title：BioMed research international

authors： Assi H,Sbaity E,Abdelsalam M,Shamseddine A

更新日期：2015-01-01 00:00:00

abstract：:It is unclear whether the methyltransferase-like 14 (METTL14) protein promotes or suppresses cancer growth. We examined the association between METTL14 expression, cancer progression, and patient prognosis in a total of 398 breast cancer tissue specimens. Significantly fewer cancer tissue specimens compared with norma...

journal_title：BioMed research international

authors： Dong XF,Wang Y,Huang BF,Hu GN,Shao JK,Wang Q,Tang CH,Wang CQ

更新日期：2020-10-20 00:00:00

abstract：:This study investigated the effect of cilostazol on proangiogenesis functions in human early endothelial progenitor cells (EPCs) in vitro and the therapeutic implication of hybrid therapy with cilostazol and human early EPCs in vivo. Cilostazol significantly increased colony-forming units and enhanced differentiation ...

journal_title：BioMed research international

authors： Tseng SY,Chao TH,Li YH,Cho CL

更新日期：2016-01-01 00:00:00

abstract：:Hematopoietic stem cells (HSCs) are unique in their capacity to give rise to all mature cells of the immune system. For years, HSC transplantation has been used for treatment of genetic and neoplastic diseases of the hematopoietic and immune systems. The sourcing of HSCs from human umbilical cord blood has salient adv...

journal_title：BioMed research international

authors： Biancotti JC,Town T

更新日期：2013-01-01 00:00:00

abstract：:Few studies assess agreement among Schistosoma haematobium eggs, measured hematuria, and self-reported metrics. We assessed agreement among four metrics at a single time point and analyzed the stability of infection across two time points with a single metric. We used data from the Eastern Region of Ghana and construc...

journal_title：BioMed research international

authors： Kosinski KC,Kulinkina AV,Tybor D,Osabutey D,Bosompem KM,Naumova EN

更新日期：2016-01-01 00:00:00

abstract：:The aim of the present study was to analyze the relationship between the sum of the four limbs' pulse pressure (Sum-PP) and brachial-ankle pulse wave velocity (baPWV) and atherosclerosis risk factors and evaluate the feasibility of Sum-PP in diagnosing atherosclerosis systemically. For the purpose, a cross-sectional s...

journal_title：BioMed research international

authors： Zheng Y,Li Z,Shu H,Liu M,Chen Z,Huang J

更新日期：2015-01-01 00:00:00

abstract：:This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of bl...

journal_title：BioMed research international

authors： Zhang Q,Zhang Y,Zhou Y,Zhang K,Zhang K,Gao L

更新日期：2016-01-01 00:00:00

abstract：:Remote organ impairments are frequent and increase patient morbidity and mortality after lower limb ischemia-reperfusion (IR). We challenged the hypothesis that lower limb IR might also impair lung, renal, and liver mitochondrial respiration. Two-hour tourniquet-induced ischemia was performed on both hindlimbs, follow...

journal_title：BioMed research international

authors： Mansour Z,Charles AL,Kindo M,Pottecher J,Chamaraux-Tran TN,Lejay A,Zoll J,Mazzucotelli JP,Geny B

更新日期：2014-01-01 00:00:00

abstract：Purpose:β-Defensin 118 (DEFB118) is a novel host defense peptide (HDP) identified in humans. To evaluate its potentials for future utilization, the DEFB118 gene was expressed in Escherichia coli (E. coli) and the recombinant protein was fully characterized. Methods:The DEFB118 protein was obtained by heterologous expr...

journal_title：BioMed research international

authors： Lin Q,Xie K,Chen D,Yu B,Mao X,Yu J,Luo J,Zheng P,Luo Y,Yan H,He J

更新日期：2020-11-09 00:00:00

abstract：Objective:It is sometimes difficult to obtain complete/partial response of large hepatocellular carcinoma (HCC) nodules by trans-arterial chemoembolization/embolization (TACE/TAE). The aim is retrospective investigation of tumor response of large HCC nodules (>7 cm) treated by the new TACE technique, repeated alternate...

journal_title：BioMed research international

authors： Irie T,Takahashi N,Kamoshida T,Kashimura J,Ariga H

更新日期：2020-01-19 00:00:00

abstract：:Despite being identified as a high risk cohort for psychosis, there has been relatively little research on the clinical presentation and assessment of Schizotypal Personality Disorder (SPD) in childhood. The current study aimed to develop a measure of childhood SPD (Melbourne Assessment of Schizotypy in Kids (MASK)) a...

journal_title：BioMed research international

authors： Jones HP,Testa RR,Ross N,Seal ML,Pantelis C,Tonge B

更新日期：2015-01-01 00:00:00

abstract：:Different animal models for peritoneal dialysis (PD) have been used in the past decades to develop PD fluids compatible with patient life and to identify markers of peritoneal fibrosis and inflammation. Only few of those studies have taken into account the importance of uraemia-induced alterations at both systemic and...

journal_title：BioMed research international

authors： Ferrantelli E,Liappas G,Keuning ED,Vila Cuenca M,González-Mateo G,Verkaik M,López-Cabrera M,Beelen RH

更新日期：2015-01-01 00:00:00

abstract：:During a spaceflight, astronauts need to live in a spacecraft on orbit for a long time, and the relationship between humans and microorganisms in the closed environment of space is not the same as on the ground. The dynamic study of microorganisms in confined space shows that with the extension of the isolation time, ...

journal_title：BioMed research international

authors： Chen Y,Wu B,Zhang C,Fan Z,Chen Y,Xin B,Xie Q

更新日期：2020-06-20 00:00:00

abstract：:Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. DEHP is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, and/or cleaning of the...

journal_title：BioMed research international

authors： Rowdhwal SSS,Chen J

更新日期：2018-02-22 00:00:00

abstract：:Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is r...

journal_title：BioMed research international

authors： Song Y,Chen Y,Li Y,Lyu X,Cui J,Cheng Y,Zheng T,Zhao L,Zhao G

更新日期：2019-04-17 00:00:00

abstract：:Atherosclerosis remains the most common cause of deaths worldwide. Endothelial cell apoptosis is an important process in the progress of atherosclerosis, as it can cause the endothelium to lose their capability in regulating the lipid homeostasis, inflammation, and immunity. Endothelial cell injury can disrupt the int...

journal_title：BioMed research international

authors： Song N,Jia L,Cao H,Ma Y,Chen N,Chen S,Lv X,Yang G

更新日期：2020-06-20 00:00:00

abstract：:Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin induces EMT and acts...

journal_title：BioMed research international

authors： Rodrigues-Diez R,Rodrigues-Diez RR,Lavoz C,Carvajal G,Droguett A,Garcia-Redondo AB,Rodriguez I,Ortiz A,Egido J,Mezzano S,Ruiz-Ortega M

更新日期：2014-01-01 00:00:00

abstract：:Combination antiemetic regimens targeting multiple molecular pathways associated with emesis have become the standard of care for prevention of chemotherapy-induced nausea and vomiting (CINV) related to highly and moderately emetogenic chemotherapies. Antiemetic consensus guidelines from several professional societies...

journal_title：BioMed research international

authors： Hesketh PJ,Aapro M,Jordan K,Schwartzberg L,Bosnjak S,Rugo H

更新日期：2015-01-01 00:00:00

abstract：:The framework of graph theory provides useful tools for investigating the neural substrates of neuropsychiatric disorders. Graph description measures may be useful as predictor variables in classification procedures. Here, we consider several centrality measures as predictor features in a classification algorithm to i...

journal_title：BioMed research international

authors： dos Santos Siqueira A,Biazoli Junior CE,Comfort WE,Rohde LA,Sato JR

更新日期：2014-01-01 00:00:00

abstract：:Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibact...

journal_title：BioMed research international

authors： Bogacz M,Morawiec T,Śmieszek-Wilczewska J,Janowska-Bogacz K,Bubiłek-Bogacz A,Rój R,Pinocy K,Mertas A

更新日期：2019-10-07 00:00:00

abstract：:An excessive pulmonary inflammatory response could explain the poor prognosis of chronic obstructive pulmonary disease (COPD) patients submitted to invasive mechanical ventilation. The aim of this study was to evaluate the response to normal tidal volume mechanical ventilation in an elastase-induced murine model of pu...

journal_title：BioMed research international

authors： Rouze A,Voiriot G,Guivarch E,Roux F,Tran Van Nhieu J,Isabey D,Brochard L,Maitre B,Mekontso-Dessap A,Boczkowski J

更新日期：2018-12-19 00:00:00

abstract：BACKGROUND:Long-term survival of total knee arthroplasty (TKA) is mainly determined by optimal positioning of the components and prosthesis alignment. Implant positioning can be optimized by computer assisted surgery (CAS). Patient specific cutting blocks (PSCB) seem to have the potential to improve component alignment...

journal_title：BioMed research international

authors： Helmy N,Dao Trong ML,Kühnel SP

更新日期：2014-01-01 00:00:00