LncRNA BLACAT1 May Serve as a Prognostic Predictor in Cancer: Evidence from a Meta-Analysis.

abstract：Objective:Hepatitis B virus (HBV) causes inflammation of the liver and is the leading cause of both liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Serine protease inhibitor Kazal type 1 (SPINK1) is an acute-phase response protein that is overexpressed in liver cancer tissue. This study investigated the clinic...

journal_title：BioMed research international

authors： Zhu C,Han H,Li J,Xu L,Liu F,Wu K,Liu X

更新日期：2019-05-22 00:00:00

abstract：:Vitamin D deficiency is common in pregnant women and infants. The present study aimed to investigate the effects of vitamin D restricted diet on the Wistar rats offspring penis morphology. Mother rats received either standard diet (SC) or vitamin D restricted (VitD) diet. At birth, offspring were divided into SC/SC (f...

journal_title：BioMed research international

authors： Fernandes-Lima F,Gregório BM,Nascimento FAM,Costa WS,Gallo CBM,Sampaio FJB

更新日期：2018-04-23 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) patients often develop bone metastases (BM), and the overall survival for these patients is usually perishing. However, a model with high accuracy for predicting the survival of NSCLC with BM is still lacking. Here, we aimed to establish a model based on artificial intelligence for p...

journal_title：BioMed research international

authors： Huang Z,Hu C,Chi C,Jiang Z,Tong Y,Zhao C

更新日期：2020-06-27 00:00:00

abstract：Objective:To investigate whether preventive administration of a proton pump inhibitor (PPI) can reduce the occurrence and development of traumatic granuloma (TG) following type IV-VI cordectomy. Methods:We retrospectively analyzed the status of postoperative granulomas in 37 patients who underwent type IV-VI cordectom...

journal_title：BioMed research international

authors： Jin X,Niu Y,Gu W,Wang J

更新日期：2020-08-10 00:00:00

abstract：:In the present study aortic murine smooth muscle cell (SMC) antigen presentation capacity was evaluated using the Eα-GFP/Y-Ae system to visualize antigen uptake through a GFP tag and tracking of Eα peptide/MHCII presentation using the Y-Ae Ab. Stimulation with IFN-γ (100 ng/mL) for 72 h caused a significant (P < 0.01)...

journal_title：BioMed research international

authors： Maddaluno M,MacRitchie N,Grassia G,Ialenti A,Butcher JP,Garside P,Brewer JM,Maffia P

更新日期：2014-01-01 00:00:00

abstract：:The incidence and rates of diagnosis of drug-induced liver injury (DILI) have been increasing in recent years as findings from basic research and the examination of clinical databases reveal information about the clinical course, etiology, and prognosis of this complex disease. The prevalence of metabolic comorbiditie...

journal_title：BioMed research international

authors： Li X,Gao P,Niu J

更新日期：2019-08-18 00:00:00

abstract：Background:Diabetes mellitus (DM) is a common disease that has an adverse impact on most orthopedic surgeries, and its prevalence has gradually increased in recent years. We aim to investigate the influence of DM on comorbidities and complications of patients undergoing primary total lower extremity arthroplasty. Meth...

journal_title：BioMed research international

authors： Qin W,Huang X,Yang H,Shen M

更新日期：2020-12-15 00:00:00

abstract：:The simultaneous effect of flexible wall and multiple stenoses on the flow and mass transfer of blood is investigated through numerical computation and simulations. The solution is obtained using the Marker and Cell technique on an axisymmetric model of Newtonian blood flow. The results compare favorably with physical...

journal_title：BioMed research international

authors： Alsemiry RD,Sarifuddin,Mandal PK,Sayed HM,Amin N

更新日期：2020-01-31 00:00:00

abstract：:Microgravity influences cell differentiation by modifying the morphogenetic field in which stem cells are embedded. Preliminary data showed indeed that stem cells are committed to selective differentiation when exposed to real or simulated microgravity. Our study provides evidence that a similar event occurs when canc...

journal_title：BioMed research international

authors： Pisanu ME,Noto A,De Vitis C,Masiello MG,Coluccia P,Proietti S,Giovagnoli MR,Ricci A,Giarnieri E,Cucina A,Ciliberto G,Bizzarri M,Mancini R

更新日期：2014-01-01 00:00:00

abstract：:We evaluated the effects of mechanical stimulation on the osteogenic differentiation of human intraoral mesenchymal stem and progenitor cells (MSPCs) using the Flexcell FX5K Tension System that mediated cyclic tensile stretch on the cells. MSPCs were isolated from human mandibular retromolar bones and characterized us...

journal_title：BioMed research international

authors： Lohberger B,Kaltenegger H,Stuendl N,Payer M,Rinner B,Leithner A

更新日期：2014-01-01 00:00:00

abstract：:Purpose. Kawasaki disease (KD) is a systemic vasculitis and is a leading cause of coronary artery lesions (CALs) in childhood. Our previous study has shown higher levels of serum Resistin in KD patients with coronary aneurysm. This study aimed at examining the association of Resistin with inflammatory cytokine express...

journal_title：BioMed research international

authors： Gao F,Si F,Feng S,Yi Q,Liu R

更新日期：2016-01-01 00:00:00

abstract：:Cancer is known to have unique metabolic features such as Warburg effect. Current cancer therapy has moved forward from cytotoxic treatment to personalized, targeted therapies, with some that could lead to specific metabolic changes, potentially monitored by imaging methods. In this paper we addressed the important as...

journal_title：BioMed research international

authors： Lin G,Chung YL

更新日期：2014-01-01 00:00:00

abstract：:There is a need to scientifically validate the claim that wild species of medicinal plants are more potent than the cultivated plants. Thus, this study evaluated the phytochemical and antioxidant properties of wild and cultivated Alepidea amatymbica. Acetone, methanol, and water extracts of the rhizome of wild and cul...

journal_title：BioMed research international

authors： Mangoale RM,Afolayan AJ

更新日期：2020-04-13 00:00:00

abstract：:This study evaluated the potential relationship between exosomal miRNAs and clinical symptoms in patients with multiple myeloma (MM). Forty-eight newly diagnosed myeloma patients and sixteen normal donors were enrolled in the study. The results showed that the relative expression levels of let-7c-5p, let-7d-5p, miR-14...

journal_title：BioMed research international

authors： Zhang ZY,Li YC,Geng CY,Wang HJ,Chen WM

更新日期：2019-12-14 00:00:00

abstract：:How to decrease intraoperative bleeding, shorten surgical time, and increase safety in spinal surgery is an important issue. Ultrasonic bone removers and FloSeal have been proven to increase safety, reduce the surgical duration, and decrease intraoperative bleeding in skull base surgery. Therefore, we aimed to compare...

journal_title：BioMed research international

authors： Chen HT,Hsu CC,Lu ML,Chen SH,Chen JM,Wu RW

更新日期：2019-05-19 00:00:00

abstract：:The aim of the study was to assess the granulocyte colony-stimulating factor (G-CSF) effects on unresponsive thin (<7 mm) endometrium in women undergoing in vitro fertilization (IVF). We included thirty-seven subjects who had thin unresponsive endometrium on the day of triggering ovulation. These patients also failed ...

journal_title：BioMed research international

authors： Kunicki M,Łukaszuk K,Woclawek-Potocka I,Liss J,Kulwikowska P,Szczyptańska J

更新日期：2014-01-01 00:00:00

abstract：:Mycobacterium bovis causes classic bovine tuberculosis, a zoonosis which is still a concern in Africa. Biofilm forming ability of two Mycobacterium bovis strains was assessed on coupons of cement, ceramic, or stainless steel in three different microbiological media at 37°C with agitation for 2, 3, or 4 weeks to determ...

journal_title：BioMed research international

authors： Adetunji VO,Kehinde AO,Bolatito OK,Chen J

更新日期：2014-01-01 00:00:00

abstract：:Gedunin is one of the major compounds found in the neem tree (Azadirachta indica). In the present study, antiproliferative potential of gedunin was evaluated in human embryonal carcinoma cells (NTERA-2, a cancer stem cell model) and peripheral blood mononuclear cells (PBMCs), using Sulforhodamine (SRB) and WST-1 assay...

journal_title：BioMed research international

authors： Tharmarajah L,Samarakoon SR,Ediriweera MK,Piyathilaka P,Tennekoon KH,Senathilake KS,Rajagopalan U,Galhena PB,Thabrew I

更新日期：2017-01-01 00:00:00

abstract：Background:Existing literature suggests that an association exists between coronary artery disease (CAD) and carpal tunnel syndrome (CTS), but few researchers have explored whether CTS is a risk for CAD. Materials and Methods:This large case-control study explored the association between CTS and CAD, using health insu...

journal_title：BioMed research international

authors： Chang YC,Chiang JH,Lay IS,Lee YC

更新日期：2019-03-03 00:00:00

abstract：Background:Adenosine, derived from the degradation of ATP via ectonucleotidases CD39 and CD73, is a critical immunosuppressive metabolite in the hypoxic microenvironment of tumor tissue. Adenosine signaling via A2aR can inhibit the antitumor immune response of CD8+ T cells. CD39 and CD73 high-expressing Tregs play a cr...

journal_title：BioMed research international

authors： Shi L,Feng M,Du S,Wei X,Song H,Yixin X,Song J,Wenxian G

更新日期：2019-12-14 00:00:00

abstract：:Contrast-induced nephropathy (CIN) remains a leading cause of iatrogenic acute kidney injury, as the usage of contrast media for imaging and intravascular intervention keeps expanding. Diabetes is an important predisposing factor for CIN, particularly in patients with renal functional impairment. Renal hypoxia, combin...

journal_title：BioMed research international

authors： Heyman SN,Rosenberger C,Rosen S,Khamaisi M

更新日期：2013-01-01 00:00:00

abstract：:The proper methylation status of histones is essential for appropriate cell lineage and organogenesis. EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development. The pig is an increasing important animal model for molecular study and pharmaceutical research. Ho...

journal_title：BioMed research international

authors： Tan B,Hong L,Qiao J,Zhou J,Xing P,Yan G,Zheng E,Cai G,Huang S,Wu Z,Gu T

更新日期：2020-10-05 00:00:00

abstract：:Eccentric exercise is characterized by initial unfavorable effects such as subcellular muscle damage, pain, reduced fiber excitability, and initial muscle weakness. However, stretch combined with overload, as in eccentric contractions, is an effective stimulus for inducing physiological and neural adaptations to train...

journal_title：BioMed research international

authors： Hedayatpour N,Falla D

更新日期：2015-01-01 00:00:00

abstract：Objective:The aim of this study is to explore the potential pathogenesis of juvenile dermatomyositis by bioinformatics analysis of gene chips, which would screen the hub genes, identify potential biomarkers, and reveal the development mechanism of juvenile dermatomyositis. Material and Methods:We retrieved juvenile de...

journal_title：BioMed research international

authors： Qiu CC,Su QS,Zhu SY,Liu RC

更新日期：2019-12-07 00:00:00

abstract：Background:Waldenström macroglobulinemia (WM) is a rare, indolent B-cell lymphoma. Clinically, chromosome 6q deletion (6q del) including loss of the B lymphocyte-induced maturation protein 1 gene (BLIMP-1) is reported to be associated with poor prognosis. However, it remains unclear how the underlying biological mechan...

journal_title：BioMed research international

authors： Sekiguchi N,Nomoto J,Nagata A,Kiyota M,Fukuda I,Yamada K,Takezako N,Kobayashi Y

更新日期：2018-10-04 00:00:00

abstract：Introduction:Rapid eye movement sleep behavior disorder (RBD) is characterized by dream-enacting behavior (shouting, punching, and falling out of bed) related to unpleasant dreams and loss of normal rapid eye movement (REM) sleep muscle atonia. Rapid eye movement sleep enhances learning and memory by regulating neurona...

journal_title：BioMed research international

authors： Dagnew B,Dagne H,Andualem Z

更新日期：2020-05-15 00:00:00

abstract：:The relationship between oxidative stress and miRNA changes in placenta as a potential mechanism involved in preeclampsia (PE) is not fully elucidated. We investigated the impact of oxidative stress on miRNAs and mRNA expression profiles of genes associated with PE in villous 3A first trimester trophoblast cells expos...

journal_title：BioMed research international

authors： Cross CE,Tolba MF,Rondelli CM,Xu M,Abdel-Rahman SZ

更新日期：2015-01-01 00:00:00

abstract：:The anaerobic skin commensal Propionibacterium acnes is an underestimated cause of human infections and clinical conditions. Previous studies have suggested a role for the bacterium in lumbar disc herniation and infection. To further investigate this, five biopsy samples were surgically excised from each of 64 patient...

journal_title：BioMed research international

authors： Rollason J,McDowell A,Albert HB,Barnard E,Worthington T,Hilton AC,Vernallis A,Patrick S,Elliott T,Lambert P

更新日期：2013-01-01 00:00:00

abstract：:Blocking glioma cell invasion has been challenging due to cancer cells that can swiftly switch their migration mode, and agents that can block more than one migration mode are sought after. We found that small molecule 2-(1H-indole-3-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE), an endogenous aryl hydrocarb...

journal_title：BioMed research international

authors： Zhao L,Shu Q,Sun H,Ma Y,Kang D,Zhao Y,Lu J,Gong P,Yang F,Wan F

更新日期：2020-10-03 00:00:00

abstract：:Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried ur...

journal_title：BioMed research international

authors： Frati ER,Martinelli M,Fasoli E,Colzani D,Bianchi S,Binda S,Olivani P,Tanzi E

更新日期：2015-01-01 00:00:00