Physiological and Neural Adaptations to Eccentric Exercise: Mechanisms and Considerations for Training.

abstract：:The role of nitric oxide and its reactive derivatives (NO x ) is well known in the pathogenesis of multiple sclerosis, which is an inflammatory disease while NO x seems to be important in coordinating inflammatory response. The...

journal_title：BioMed research international

authors： Niedziela N,Adamczyk-Sowa M,Niedziela JT,Mazur B,Kluczewska E,Sowa P,Gąsior M

更新日期：2016-01-01 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：Introduction:The purpose of this study was to investigate the difference in surgical outcomes between symptomatic and asymptomatic patients with primary hyperparathyroidism (PHPT) and between patients with high serum calcium and those with normal blood calcium, as well as to explore the epidemiological trend of PHPT in...

journal_title：BioMed research international

authors： Yu Q,Liu K,Ma D,Xie C,Wu Y,Dai W,Jiang H

更新日期：2019-07-01 00:00:00

abstract：:Aldosterone synthase (CYP11B2) is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS) and lead to hypertension. Therefore, research and development of CYP...

journal_title：BioMed research international

authors： Luo G,Lu F,Qiao L,Chen X,Li G,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：:The selection of the most relevant molecular descriptors to describe a target variable in the context of QSAR (Quantitative Structure-Activity Relationship) modelling is a challenging combinatorial optimization problem. In this paper, a novel software tool for addressing this task in the context of regression and clas...

journal_title：BioMed research international

authors： Martínez MJ,Razuc M,Ponzoni I

更新日期：2019-02-17 00:00:00

abstract：BACKGROUND:The prognosis of patients with advanced oropharyngeal carcinoma (OPSCC) is generally poor. The aim of this study is to investigate the different therapeutic approaches and identify prognostic factors associated with a worse outcome for patients treated for T4a OPSCC, in order to improve treatment selection f...

journal_title：BioMed research international

authors： Psychogios G,Mantsopoulos K,Agaimy A,Brunner K,Mangold E,Zenk J,Iro H

更新日期：2014-01-01 00:00:00

abstract：:Arthritogenic alphaviruses, including Ross River virus (RRV), Chikungunya virus (CHIKV), Sindbis virus (SINV), Mayaro virus (MAYV), O'nyong-nyong virus (ONNV), and Barmah Forest virus (BFV), cause incapacitating and long lasting articular disease/myalgia. Outbreaks of viral arthritis and the global distribution of the...

journal_title：BioMed research international

authors： Assunção-Miranda I,Cruz-Oliveira C,Da Poian AT

更新日期：2013-01-01 00:00:00

abstract：:Mixed-phase TiO2 nanocomposite thin films consisting of anatase and rutile prepared on commercially pure Ti sheets via the electrochemical anodization and annealing treatments were investigated in terms of their photocatalytic activity for antibacterial use around dental implants. The resulting films were characterize...

journal_title：BioMed research international

authors： Yeniyol S,Mutlu I,He Z,Yüksel B,Boylan RJ,Ürgen M,Karabuda ZC,Basegmez C,Ricci JL

更新日期：2015-01-01 00:00:00

abstract：:Owing to its hydrophilicity, negative charge, small size, and labile degradation by endogenous nucleases, small interfering RNA (siRNA) delivery must be achieved by a carrier system. In this study, cationic copolymers composed of low-molecular-weight polyethylenimine and polythiophenes were synthesized and evaluated a...

journal_title：BioMed research international

authors： He P,Hagiwara K,Chong H,Yu HH,Ito Y

更新日期：2015-01-01 00:00:00

abstract：Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

journal_title：BioMed research international

authors： Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

更新日期：2020-12-19 00:00:00

abstract：Results:In 221 cycles from 138 patients (104 cycles requiring HLA matching), 90.5% had embryo(s) biopsied for genetic testing. There were 119 embryo transfers for thalassemia (76) and thalassemia-HLA cases (43), respectively, resulting in overall clinical pregnancy rates of 54.6%, implantation rates of 45.7%, and live ...

journal_title：BioMed research international

authors： Tiewsiri K,Manipalviratn S,Sutheesophon W,Vanichsetakul P,Thaijaroen P,Ketcharoon P,Bradley CK,McArthur SJ,Krutsawad W,Marshall JTA,Papadopoulos KI

更新日期：2020-06-26 00:00:00

abstract：:The ability of Aspergillus niger strain to reduce organic and mineral pollution as well as the toxicity of two tannery wastewaters, the unhairing effluent (UE) and the final effluent (FE), taken from a local Tunisian tannery and under nonsterile conditions, was studied. Raw effluents show alkaline pH ≥11; thus experim...

journal_title：BioMed research international

authors： Boujelben R,Ellouze M,Sayadi S

更新日期：2019-06-03 00:00:00

abstract：:The large-scale production of cardiomyocytes is a key step in the development of cell therapy and tissue engineering to treat cardiovascular diseases, particularly those caused by ischemia. The main objective of this study was to establish a procedure for the efficient production of cardiomyocytes by reprogramming mes...

journal_title：BioMed research international

authors： Zanetti BF,Gomes WJ,Han SW

更新日期：2013-01-01 00:00:00

abstract：:COVID-19 is a pandemic which has spread to more than 200 countries. Its high transmission rate makes it difficult to control. To date, no specific treatment has been found as a cure for the disease. Therefore, prediction of COVID-19 cases provides a useful insight to mitigate the disease. This study aims to model and ...

journal_title：BioMed research international

authors： Attanayake AMCH,Perera SSN

更新日期：2020-12-03 00:00:00

abstract：:Several intestinal parasites of baboons are of zoonotic importance, especially where there is considerable interaction between the baboons and humans. The identification of gastrointestinal parasite infections of baboons (Papio anubis) was undertaken at the Shai Hills Reserve Resort, Ghana. A total of 51 faecal sample...

journal_title：BioMed research international

authors： Larbi JA,Akyeampong S,Abubakari A,Offei Addo S,Okoto D,Hanson H

更新日期：2020-03-11 00:00:00

abstract：Objective:To investigate the clinicopathological characteristics and risk factors in patients with lung cancer and COPD. Materials and Methods:We retrospectively reviewed the clinical data of 282 patients with lung cancer, including 174 and 108 patients with and without COPD, respectively. Information on age, sex, smo...

journal_title：BioMed research international

authors： Miao JL,Cai JJ,Qin XF,Liu RJ

更新日期：2018-02-14 00:00:00

abstract：:Lung cancer consists of two main subtypes: small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) that are classified according to their physiological phenotypes. In this study, we have developed a network-based approach to identify molecular biomarkers that can distinguish SCLC from NSCLC. By identifyin...

journal_title：BioMed research international

authors： Long F,Su JH,Liang B,Su LL,Jiang SJ

更新日期：2015-01-01 00:00:00

abstract：:Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs are bound to conforma...

journal_title：BioMed research international

authors： Hu WG,Yin J,Chau D,Hu CC,Lillico D,Yu J,Negrych LM,Cherwonogrodzky JW

更新日期：2013-01-01 00:00:00

abstract：:The anaerobic skin commensal Propionibacterium acnes is an underestimated cause of human infections and clinical conditions. Previous studies have suggested a role for the bacterium in lumbar disc herniation and infection. To further investigate this, five biopsy samples were surgically excised from each of 64 patient...

journal_title：BioMed research international

authors： Rollason J,McDowell A,Albert HB,Barnard E,Worthington T,Hilton AC,Vernallis A,Patrick S,Elliott T,Lambert P

更新日期：2013-01-01 00:00:00

abstract：:With the increasing demand for noninvasive approaches in monitoring head and neck cancer, circulating nucleic acids have been shown to be a promising tool. We focused on the global transcriptome of serum samples of head and neck squamous cell carcinoma (HNSCC) patients in comparison with healthy individuals. We compar...

journal_title：BioMed research international

authors： Čapková M,Šáchová J,Strnad H,Kolář M,Hroudová M,Chovanec M,Čada Z,Šteffl M,Valach J,Kastner J,Vlček Č,Smetana K Jr,Plzák J

更新日期：2014-01-01 00:00:00

abstract：:cir-ITCH, a well-known tumor-suppressive circular RNA, plays a critical role in different cancers. However, its expression and functional role in prostate cancer (PCa) are unclear. Herein, we explored the potential mechanism and tumor-inhibiting role of cir-ITCH in PCa. Using reverse transcriptase polymerase chain rea...

journal_title：BioMed research international

authors： Li S,Yu C,Zhang Y,Liu J,Jia Y,Sun F,Zhang P,Li J,Guo L,Xiao H,Gao F,Deng X,Cai Z,Cai J

更新日期：2020-08-20 00:00:00

abstract：Objective:Hepatitis B virus (HBV) causes inflammation of the liver and is the leading cause of both liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Serine protease inhibitor Kazal type 1 (SPINK1) is an acute-phase response protein that is overexpressed in liver cancer tissue. This study investigated the clinic...

journal_title：BioMed research international

authors： Zhu C,Han H,Li J,Xu L,Liu F,Wu K,Liu X

更新日期：2019-05-22 00:00:00

abstract：:In continuance of our search for anticancer agents, we report herein the synthesis and anticancer activity of some novel oxadiazole analogues. The compounds were screened for anticancer activity as per National Cancer Institute (NCI US) protocol on leukemia, melanoma, lung, colon, CNS, ovarian, renal, prostate, and br...

journal_title：BioMed research international

authors： Ahsan MJ,Sharma J,Singh M,Jadav SS,Yasmin S

更新日期：2014-01-01 00:00:00

abstract：:Dysfunctions of chaperone-mediated autophagy (CMA), the main catabolic pathway for alpha-synuclein, have been linked to the pathogenesis of Parkinson's disease (PD). Since till now there is limited information on how PD-related toxins may affect CMA, in this study we explored the effect of mitochondrial complex I inhi...

journal_title：BioMed research international

authors： Sala G,Arosio A,Stefanoni G,Melchionda L,Riva C,Marinig D,Brighina L,Ferrarese C

更新日期：2013-01-01 00:00:00

abstract：:Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...

journal_title：BioMed research international

authors： Léonard B,Kridelka F,Delbecque K,Goffin F,Demoulin S,Doyen J,Delvenne P

更新日期：2014-01-01 00:00:00

abstract：:Background. Genome-wide association studies (GWAS) have shown its revolutionary power in seeking the influenced loci on complex diseases genetically. Thousands of replicated loci for common traits are helpful in diseases risk assessment. However it is still difficult to elucidate the variations in these loci that dire...

journal_title：BioMed research international

authors： Ma LX,Wang YJ,Wang JF,Li X,Hao P

更新日期：2013-01-01 00:00:00

abstract：:Because of their high incidence and mortality solid cancers are a major health problem worldwide. Although several new biomarkers and potential targets for therapy have been identified through biomolecular research in the last years, the effects on patients' outcome are still unsatisfactory. Increasing evidence indica...

journal_title：BioMed research international

authors： Lastraioli E,Lottini T,Bencini L,Bernini M,Arcangeli A

更新日期：2015-01-01 00:00:00

abstract：:Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...

journal_title：BioMed research international

authors： Ding S,Huang H,Xu Y,Shen L,Zhong C,Zheng S

更新日期：2020-01-11 00:00:00

abstract：:There were no systematic researches about autophagy-related long noncoding RNA (lncRNA) signatures to predict the survival of patients with colon adenocarcinoma. It was necessary to set up corresponding autophagy-related lncRNA signatures. The expression profiles of lncRNAs which contained 480 colon adenocarcinoma sam...

journal_title：BioMed research international

authors： Zhou W,Zhang S,Li HB,Cai Z,Tang S,Chen LX,Lang JY,Chen Z,Chen XL

更新日期：2020-09-02 00:00:00

abstract：:Numerous studies have shown that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of human cardiovascular diseases. However, whether lncRNA ezrin antisense RNA 1 (EZR-AS1) is associated with the progression of coronary heart disease (CHD) remains unclear. Accordingly, the aim of th...

journal_title：BioMed research international

authors： You G,Long X,Song F,Huang J,Tian M,Xiao Y,Deng S,Wu Q

更新日期：2020-05-22 00:00:00