当前位置： SCI文献检索 > Biomed Research International期刊下所有文献 > Analysis of the Clinicopathological Characteristics and Risk Factors in Patients with Lung Cancer and Chronic Obstructive Pulmonary Disease.

Analysis of the Clinicopathological Characteristics and Risk Factors in Patients with Lung Cancer and Chronic Obstructive Pulmonary Disease.

Abstract：

Objective:To investigate the clinicopathological characteristics and risk factors in patients with lung cancer and COPD. Materials and Methods:We retrospectively reviewed the clinical data of 282 patients with lung cancer, including 174 and 108 patients with and without COPD, respectively. Information on age, sex, smoking status, and histologic type was obtained from medical records. Results:Lung cancer patients with COPD and those with the chronic bronchitis (CB) phenotype had higher smoking indices compared to those without COPD (723.95 ± 631.48 and 920.95 ± 712.93 versus 418.40 ± 506.84; P = 0.010; P = 0.001, resp.), and current smokers accounted for significantly higher proportions of lung cancer patients with COPD and the CB phenotype versus without COPD (51.15% and 63.74% versus 35.19%; P = 0.009; P = 0.001, resp.). Adenocarcinoma was significantly more common in lung cancer patients without versus with COPD (48.15% versus 35.63%; P = 0.037), whereas small cell lung cancer was more common in patients with COPD (23.56% versus 13.89%). Among patients with COPD, male sex (odds ratio [OR], 19.946; P < 0.001), current smokers (OR: 6.588; P = 0.001), and age ≥ 75 years (OR: 2.670; P = 0.008) were identified as high-risk factors. Conclusion:The risk factors for COPD among lung cancer patients were age ≥ 75 years, current smokers with the CB phenotype, and male sex.

journal_name

Biomed Res Int

journal_title

BioMed research international

authors

Miao JL,Cai JJ,Qin XF,Liu RJ

doi

10.1155/2018/8398156

subject

Has Abstract

pub_date

2018-02-14 00:00:00

pages

8398156

eissn

2314-6133

issn

2314-6141

journal_volume

2018

pub_type

杂志文章

相关文献

Biomed Research International文献大全
  • Fractionated Stereotactic Radiation Therapy Using Volumetric Modulated Arc Therapy in Patients with Solitary Brain Metastases.

    abstract：Purpose:To analyze retrospectively the clinical efficacy and safety for patients treated with fractionated stereotactic radiation therapy (FSRT) using volumetric modulated arc therapy. Methods:Between 2016 and 2017, 46 patients with solitary brain metastasis who underwent FSRT consisting of 25-40 Gy/5 fractions were r...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/6342057

    authors： Zhou C,Xia Y,Huang P,Guan L,Shen X,Hao D,Chen M,Ren H,Lian L,Yin H

    更新日期：2020-09-09 00:00:00

  • Analysis of Synonymous Codon Usage Bias in Flaviviridae Virus.

    abstract：Background:Flaviviridae viruses are single-stranded, positive-sense RNA viruses, which threat human constantly mediated by mosquitoes, ticks, and sandflies. Considering the recent increase in the prevalence of the family virus and its risk potential, we investigated the codon usage pattern to understand its evolutionar...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/5857285

    authors： Yao H,Chen M,Tang Z

    更新日期：2019-06-27 00:00:00

  • LRRK2 G2385R and R1628P mutations are associated with an increased risk of Parkinson's disease in the Malaysian population.

    abstract：:The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk of developing PD in certa...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2014/867321

    authors： Gopalai AA,Lim SY,Chua JY,Tey S,Lim TT,Mohamed Ibrahim N,Tan AH,Eow GB,Abdul Aziz Z,Puvanarajah SD,Viswanathan S,Looi I,Lim SK,Tan LP,Chong YB,Tan CT,Zhao Y,Tan EK,Ahmad-Annuar A

    更新日期：2014-01-01 00:00:00

  • Acupoint Catgut Embedding Improves the Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome in Rats.

    abstract：Background:This study investigated the potential therapeutic effects of acupoint catgut embedding (ACE) at ST36 and BL13 on lipopolysaccharide- (LPS-) induced acute respiratory distress syndrome (ARDS) in rats. Materials and Methods:Male Sprague-Dawley rats were randomized into the normal saline (NS group with a sham ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/2394734

    authors： Li D,Sun T,Chi L,Zhao D,Li W

    更新日期：2020-05-02 00:00:00

  • CSF-S100B Is a Potential Candidate Biomarker for Neuromyelitis Optica Spectrum Disorders.

    abstract：:Astrocytic impairment is a pathologic feature of neuromyelitis optica spectrum disorder (NMOSD). S100B and glial fibrillary acidic protein (GFAP) are the two most commonly used astrocytic markers. The aim of this study was to evaluate whether CSF-S100B could serve as a marker of NMOSD. We enrolled 49 NMOSD patients [2...

    journal_title：BioMed research international

    pub_type： 临床试验,杂志文章

    doi：10.1155/2018/5381239

    authors： Wei Y,Chang H,Li X,Du L,Xu W,Cong H,Yao Y,Zhang X,Yin L

    更新日期：2018-10-22 00:00:00

  • Potential Role of Carvedilol in the Cardiac Immune Response Induced by Experimental Infection with Trypanosoma cruzi.

    abstract：:Trypanosoma cruzi causes a cardiac infection characterized by an inflammatory imbalance that could become the inciting factor of the illness. To this end, we evaluated the role of carvedilol, a beta-blocker with potential immunomodulatory properties, on the immune response in C57BL/6 mice infected with VL-10 strain of...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2017/9205062

    authors： Horta AL,Leite AL,Paula Costa G,Figueiredo VP,Talvani A

    更新日期：2017-01-01 00:00:00

  • Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy.

    abstract：:Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can b...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2019/6104738

    authors： Kang J,Fan W,Deng Q,He H,Huang F

    更新日期：2019-01-29 00:00:00

  • The Effect of Bone Marrow-Derived Mesenchymal Stem Cells and Their Conditioned Media Topically Delivered in Fibrin Glue on Chronic Wound Healing in Rats.

    abstract：:Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent a modern approach for management of chronic skin injuries. In this work, we describe BM-MSCs application versus their conditioned media (CM) when delivered topically admixed with fibrin glue to enhance the healing of chronic excisional wounds in rats. Fift...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2015/846062

    authors： Mehanna RA,Nabil I,Attia N,Bary AA,Razek KA,Ahmed TA,Elsayed F

    更新日期：2015-01-01 00:00:00

  • A Decade of Progress Using Virtual Reality for Poststroke Lower Extremity Rehabilitation: Systematic Review of the Intervention Methods.

    abstract：OBJECTIVE:To develop a systematic review of the literature, to describe the different virtual reality (VR) interventions and interactive videogames applied to the lower extremity (LE) of stroke patients, and to analyse the results according to the most frequently used outcome measures. MATERIAL AND METHODS:An electron...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2015/342529

    authors： Luque-Moreno C,Ferragut-Garcías A,Rodríguez-Blanco C,Heredia-Rizo AM,Oliva-Pascual-Vaca J,Kiper P,Oliva-Pascual-Vaca Á

    更新日期：2015-01-01 00:00:00

  • Formulation and evaluation of chitosan-chondroitin sulphate based nasal inserts for zolmitriptan.

    abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2013/958465

    authors： Kaur K,Kaur G

    更新日期：2013-01-01 00:00:00

  • Recurrence-Associated Multi-RNA Signature to Predict Disease-Free Survival for Ovarian Cancer Patients.

    abstract：:Ovarian cancer (OvCa) is an intractable gynecological malignancy due to the high recurrence rate. Several molecular biomarkers have been previously screened for early identifying patients with a high recurrence risk and poor prognosis. However, all the known studies focused on a single type of RNAs, not integrating va...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2020/1618527

    authors： Zhang Y,Ye Q,He J,Chen P,Wan J,Li J,Yang Y,Li X

    更新日期：2020-02-14 00:00:00

  • Cloning and expression of synthetic genes encoding the broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris.

    abstract：:We have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris. Synthetic genes, matching the codon usage of P. pastoris, were designed from the known mature amino acid sequence of these bacter...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2015/767183

    authors： Arbulu S,Jiménez JJ,Gútiez L,Cintas LM,Herranz C,Hernández PE

    更新日期：2015-01-01 00:00:00

  • Bioaccumulation experiments in mussels contaminated with the food-borne pathogen Arcobacter butzleri: preliminary data for risk assessment.

    abstract：:The aim of this study was to evaluate, at a laboratory scale, the ability of this microorganism to grow in seawater and bioaccumulate in mussels (Mytilus galloprovincialis) maintained in constantly aerated tanks, containing twenty litres of artificial seawater. Three concentrations of A. butzleri LMG 10828(T) were tes...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2013/153419

    authors： Ottaviani D,Chierichetti S,Rocchegiani E,Bartolini C,Masini L,Santarelli S,Leoni F

    更新日期：2013-01-01 00:00:00

  • Validation of an Endoscopic Fibre-Optic Pressure Sensor for Noninvasive Measurement of Variceal Pressure.

    abstract：:In this study, the authors have developed endoscopic fibre-optic pressure sensor to detect variceal pressure and presented the validation of in vivo and in vitro studies, because the HVPG requires catheterization of hepatic veins, which is invasive and inconvenient. Compared with HVPG, it is better to measure directly...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/1893474

    authors： Sun B,Kong DR,Li SW,Yu DF,Wang GJ,Yu FF,Wu Q,Xu JM

    更新日期：2016-01-01 00:00:00

  • Outcome of Extracorporeal Shock Wave Therapy for Insertional Achilles Tendinopathy with and without Haglund's Deformity.

    abstract：:Purpose. To compare the results of extracorporeal shock wave therapy (ESWT) for insertional Achilles tendinopathy (IAT) with or without Haglund's deformity. Methods. Between September 2014 and May 2015, all patients who underwent ESWT were retrospectively enrolled in this study. A total of 67 patients were available f...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/6315846

    authors： Wu Z,Yao W,Chen S,Li Y

    更新日期：2016-01-01 00:00:00

  • Pretreatment Serum Cystatin C Levels Predict Renal Function, but Not Tumor Characteristics, in Patients with Prostate Neoplasia.

    abstract：:To evaluate the role of Cystatin C (Cys-C) in tumorigenesis and progression of prostate cancer (PCa), we retrospectively collected the clinical information from the records of 492 benign prostatic hyperplasia (BPH), 48 prostatic intraepithelial neoplasia (PIN), and 173 PCa patients, whose disease was newly diagnosed a...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2017/7450459

    authors： Yang F,Li D,Di Y,Zhang Y,Zang Y,Ren J,Yan L,Zhou Z,Liu H,Xu Z

    更新日期：2017-01-01 00:00:00

  • Syringobulbia in Patients with Chiari Malformation Type I: A Systematic Review.

    abstract：:This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic pre...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/4829102

    authors： Shen J,Shen J,Huang K,Wu Y,Pan J,Zhan R

    更新日期：2019-03-19 00:00:00

  • Coconut Water: An Unexpected Source of Urinary Citrate.

    abstract：Purpose:Coconut water has long been touted for its medicinal qualities including natural hydration. We sought to determine whether its consumption would induce changes to urinary lithogenic factors beyond changes in urine volume. Materials and Methods:After Institutional Review Board approval, volunteers with no prior...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/3061742

    authors： Patel RM,Jiang P,Asplin J,Granja I,Capretz T,Osann K,Okhunov Z,Landman J,Clayman RV

    更新日期：2018-11-01 00:00:00

  • Enhanced Production of Polymyxin E in Paenibacillus polymyxa by Replacement of Glucose by Starch.

    abstract：:Polymyxin E or colistin, produced by Paenibacillus polymyxa, is an important antibiotic against Gram-negative pathogens. The objective of this study is to evaluate the effect of starch in fermentation medium on colistin biosynthesis in P. polymyxa. The results indicated that replacement of glucose by starch stimulated...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/1934309

    authors： Yu Z,Sun Z,Yin J,Qiu J

    更新日期：2018-10-14 00:00:00

  • Metformin Prevents Nonunion after Three-Cannulated-Screw Fixation in Displaced Femoral Neck Fractures: A Retrospective Study.

    abstract：:Patients aged from 40 to 60 with displaced fractures of the femoral neck (Garden III or IV) who received fixation with three cannulated screws from January 2005 to December 2012 were evaluated retrospectively for the development of nonunion. Plasma HbA1C, a marker for long-term plasma glucose level, anti-T2DM medicati...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/5682541

    authors： Zhu XZ,Zheng XY

    更新日期：2016-01-01 00:00:00

  • Prediction and Prevention of Acute Kidney Injury after Cardiac Surgery.

    abstract：:The incidence of acute kidney injury after cardiac surgery (CS-AKI) ranges from 33% to 94% and is associated with a high incidence of morbidity and mortality. The etiology is suggested to be multifactorial and related to almost all aspects of perioperative management. Numerous studies have reported the risk factors an...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2016/2985148

    authors： Shin SR,Kim WH,Kim DJ,Shin IW,Sohn JT

    更新日期：2016-01-01 00:00:00

  • Positive Association between ANKRD55 Polymorphism 7731626 and Dermatomyositis/Polymyositis with Interstitial Lung Disease in Chinese Han Population.

    abstract：:Single nucleotide polymorphisms (SNPs) in TNFSF4 and ANKRD55 genes have been shown to be associated with several autoimmune diseases, although whether these genes are susceptibility genes for dermatomyositis/polymyositis (DM/PM) has, to date, not been reported. This study aimed to investigate the potential association...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2017/2905987

    authors： Li L,Chen S,Wen X,Wang Q,Lv G,Li J,Yang F,Zhang F,Li Y

    更新日期：2017-01-01 00:00:00

  • Effects of Vitamin D Restricted Diet Administered during Perinatal and Postnatal Periods on the Penis of Wistar Rats.

    abstract：:Vitamin D deficiency is common in pregnant women and infants. The present study aimed to investigate the effects of vitamin D restricted diet on the Wistar rats offspring penis morphology. Mother rats received either standard diet (SC) or vitamin D restricted (VitD) diet. At birth, offspring were divided into SC/SC (f...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/6030646

    authors： Fernandes-Lima F,Gregório BM,Nascimento FAM,Costa WS,Gallo CBM,Sampaio FJB

    更新日期：2018-04-23 00:00:00

  • Effects of prepolymerized particle size and polymerization kinetics on volumetric shrinkage of dental modeling resins.

    abstract：:Dental modeling resins have been developed for use in areas where highly precise resin structures are needed. The manufacturers claim that these polymethyl methacrylate/methyl methacrylate (PMMA/MMA) resins show little or no shrinkage after polymerization. This study examined the polymerization shrinkage of five denta...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2014/914739

    authors： Kwon TY,Ha JY,Chun JN,Son JS,Kim KH

    更新日期：2014-01-01 00:00:00

  • Multicriteria Decision Model and Thermal Pretreatment of Hotel Food Waste for Robust Output to Biogas: Case Study from City of Jaipur, India.

    abstract：:The anaerobic batch test (45 days at 37°C) was performed to describe the effect of thermal pretreatment at moderate temperatures (60, 80, and 100°C) over durations of 10 and 20 minutes on the enhancement of biogas production using hotel food waste from city of Jaipur, India. The results showed that the total cumulativ...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/9416249

    authors： Gandhi P,Paritosh K,Pareek N,Mathur S,Lizasoain J,Gronauer A,Bauer A,Vivekanand V

    更新日期：2018-09-16 00:00:00

  • Resistin Enhances Inflammatory Cytokine Production in Coronary Artery Tissues by Activating the NF-κB Signaling.

    abstract：:Purpose. Kawasaki disease (KD) is a systemic vasculitis and is a leading cause of coronary artery lesions (CALs) in childhood. Our previous study has shown higher levels of serum Resistin in KD patients with coronary aneurysm. This study aimed at examining the association of Resistin with inflammatory cytokine express...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2016/3296437

    authors： Gao F,Si F,Feng S,Yi Q,Liu R

    更新日期：2016-01-01 00:00:00

  • Effect of Different Body Postures on the Severity of Stuttering in Young Adults with Developmental Stuttering.

    abstract：Objective:The current study aimed to investigate the effects of body position on the level and severity of stuttering in young adults with developmental stuttering. Methods:A total of 24 subjects (male: 17; female: 7; mean age: 24.9 ± 6.2 years) with developmental stuttering participated. The participants were asked t...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2019/1817906

    authors： Almudhi A,Zafar H,Anwer S,Alghadir A

    更新日期：2019-08-05 00:00:00

  • Imaging and Management of Incidental Renal Lesions.

    abstract：:The increased use of imaging modalities in the last years has led to a greater incidence in depicting abdominal incidental lesions. In particular, "incidentalomas" of the kidney are discovered in asymptomatic patients or patients who suffer from diseases not directly related to the kidneys. The aim of this paper is to...

    journal_title：BioMed research international

    pub_type： 杂志文章,评审

    doi：10.1155/2017/1854027

    authors： Mazziotti S,Cicero G,D'Angelo T,Marino MA,Visalli C,Salamone I,Ascenti G,Blandino A

    更新日期：2017-01-01 00:00:00

  • Gene profiling of bone around orthodontic mini-implants by RNA-sequencing analysis.

    abstract：:This study aimed to evaluate the genes that were expressed in the healing bones around SLA-treated titanium orthodontic mini-implants in a beagle at early (1-week) and late (4-week) stages with RNA-sequencing (RNA-Seq). Samples from sites of surgical defects were used as controls. Total RNA was extracted from the tiss...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2015/538080

    authors： Nahm KY,Heo JS,Lee JH,Lee DY,Chung KR,Ahn HW,Kim SH

    更新日期：2015-01-01 00:00:00

  • Awareness of Pleiotropic and Cardioprotective Effect of Statins in Patients with Coronary Artery Disease.

    abstract：Background:Statins are commonly used in the secondary prevention of coronary artery disease. Studies have shown that the rate of statin use is low among patients with coronary artery disease. In this study, we aimed to investigate the reasons for poor patient compliance with statin treatment. Methods:A total of 504 pa...

    journal_title：BioMed research international

    pub_type： 杂志文章

    doi：10.1155/2018/8961690

    authors： Ozkan B,Örsçelik Ö,Uyar H,Ballı M,Güçer E,Aslan O,Temel G,Çelik A,Türkay Özcan İ

    更新日期：2018-06-07 00:00:00