Cloning and expression of synthetic genes encoding the broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris.

abstract：:Carbonic anhydrases (CAs) are enzymes that catalyse the reversible hydration of CO2 to bicarbonate. CA XII is considered a potential biomarker of tumor cells and a promising target for specific therapies. The aim of the current study was to develop new monoclonal antibodies (MAbs) against human recombinant CA XII and ...

journal_title：BioMed research international

authors： Dekaminaviciute D,Lasickiene R,Parkkila S,Jogaite V,Matuliene J,Matulis D,Zvirbliene A

更新日期：2014-01-01 00:00:00

abstract：:Coronary computed tomography angiography (CCTA) has been recently evaluated for its ability to assess coronary plaque characteristics, including plaque composition. Identification of the relationship between plaque composition by CCTA and patient clinical presentations may provide insight into the pathophysiology of c...

journal_title：BioMed research international

authors： Sun Z,Xu L

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this paper is to review some of the psychological and neural mechanisms behind mindfulness practice in order to explore the unique factors that account for its positive impact on emotional regulation and health. After reviewing the mechanisms of mindfulness and its effects on clinical populations we wil...

journal_title：BioMed research international

authors： Grecucci A,Pappaianni E,Siugzdaite R,Theuninck A,Job R

更新日期：2015-01-01 00:00:00

abstract：:This paper describes a pilot study using a prototype telerehabilitation system (Ghostman). Ghostman is a visual augmentation system designed to allow a physical therapist and patient to inhabit each other's viewpoint in an augmented real-world environment. This allows the therapist to deliver instruction remotely and ...

journal_title：BioMed research international

authors： Chinthammit W,Merritt T,Pedersen S,Williams A,Visentin D,Rowe R,Furness T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Residual neuromuscular block (NMB) after general anesthesia has been associated with pulmonary dysfunction and hypoxia, which are both associated with postoperative delirium (POD). We evaluated the effects of sugammadex on POD in elderly patients who underwent hip fracture surgery. METHODS:Medical records o...

journal_title：BioMed research international

authors： Oh CS,Rhee KY,Yoon TG,Woo NS,Hong SW,Kim SH

更新日期：2016-01-01 00:00:00

abstract：:In preclinical treatment of polytraumatized patients crystalloids are preferentially used. To avoid metabolic acidosis, metabolizable anions like lactate or acetate are used to replace chloride in these solutions. We here studied the effects of malated Ringer's in resuscitation of both shock severities in comparison t...

journal_title：BioMed research international

authors： Keitel J,Hussmann B,Lendemans S,de Groot H,Rohrig R

更新日期：2015-01-01 00:00:00

abstract：:Diabetes-triggered apoptosis of Schwann cells (SC) contributes to the degradation of diabetic peripheral neuropathy (DNP). In recent years, mesenchymal stem cells (MSC) were applied to DPN repair and it was demonstrated that paracrine secretion played a key role in neuroprotection exerted by MSC. Erythropoietin (EPO) ...

journal_title：BioMed research international

authors： Zhang S,Shi B

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Recovery of walking outdoors after hip fracture is important for equal participation in the community. The causes of poor recovery are not fully understood. This study investigates recovery of walking outdoors and associated determinants after hip fracture. METHODS:A prospective follow-up study, among clinical...

journal_title：BioMed research international

authors： Salpakoski A,Törmäkangas T,Edgren J,Sihvonen S,Pekkonen M,Heinonen A,Pesola M,Kallinen M,Rantanen T,Sipilä S

更新日期：2014-01-01 00:00:00

abstract：:Xiaoxuming decoction (XXMD), a classic traditional Chinese medicine (TCM) prescription, has been used as a therapeutic in the treatment of stroke in clinical practice for over 1200 years. However, the pharmacological mechanisms of XXMD have not yet been elucidated. The purpose of this study was to develop neuroprotect...

journal_title：BioMed research international

authors： Yang S,Shen Y,Lu W,Yang Y,Wang H,Li L,Wu C,Du G

更新日期：2019-07-10 00:00:00

abstract：Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...

journal_title：BioMed research international

authors： Kartinah NT,Fadilah F,Ibrahim EI,Suryati Y

更新日期：2019-11-11 00:00:00

abstract：OBJECTIVES:To investigate the availability of correction of mandibular plane using software for vertical measurements in cone beam computed tomography (CBCT) according to the sites of the mandible. METHODS:CBCT scans of six dry mandibles were performed at 0-, 5-, 10-, 15-, and 20-degree angles relative to CBCT scannin...

journal_title：BioMed research international

authors： Han SS,Lee KM,Kim KD

更新日期：2015-01-01 00:00:00

abstract：:The aims of this study were to investigate the reasons of transfers from long-term care hospitals (LTCHs) to emergency departments (EDs) of university hospitals in geriatric patients and to categorize the avoidable causes of these transfers. This retrospective multicenter study involved patients aged 65 years and olde...

journal_title：BioMed research international

authors： Kim K,Lee DH,Yune HY,Wee JH,Kim DH,Kim EC,Lim JY,Choi SP

更新日期：2019-06-19 00:00:00

abstract：:Body weight supported locomotor training uses neuroplasticity principles to improve recovery following a spinal cord injury (SCI). Steady state locomotion using the same body weight support (BWS) percent was compared in 7 males (42.6 ± 4.29 years) with incomplete SCI and matched (gender, age) noninjured controls (42.7...

journal_title：BioMed research international

authors： Fenuta AM,Hicks AL

更新日期：2014-01-01 00:00:00

abstract：:Diabetes mellitus is a disease which has affected 415 million patients in 2015. In an effort to replace the significant demands on transplantation and morbidity associated with transplantation, the production of β-like cells differentiated from induced pluripotent stem cells (iPSCs) was evaluated. This approach is ass...

journal_title：BioMed research international

authors： Wan J,Huang Y,Zhou P,Guo Y,Wu C,Zhu S,Wang Y,Wang L,Lu Y,Wang Z

更新日期：2017-01-01 00:00:00

abstract：:Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin induces EMT and acts...

journal_title：BioMed research international

authors： Rodrigues-Diez R,Rodrigues-Diez RR,Lavoz C,Carvajal G,Droguett A,Garcia-Redondo AB,Rodriguez I,Ortiz A,Egido J,Mezzano S,Ruiz-Ortega M

更新日期：2014-01-01 00:00:00

abstract：:Coronary artery diseases (CAD) and heart failure have high mortality rate in the world, although much progress has been made in this field in last two decades. There is still a clinical need for a novel diagnostic approach and a therapeutic strategy to decrease the incidence of CAD. MicroRNAs (miRNAs) are highly conse...

journal_title：BioMed research international

authors： Nishiguchi T,Imanishi T,Akasaka T

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:The aim of this report is to study the graft and patient survival in a large cohort of recipients with an analysis of factors that may affect the final outcomes. METHODS:Between March 1976 and March 2008, 1967 consecutive live-donor renal transplants were carried out. Various variables that may have an im...

journal_title：BioMed research international

authors： Ghoneim MA,Bakr MA,Refaie AF,Akl AI,Shokeir AA,Shehab El-Dein AB,Ammar HM,Ismail AM,Sheashaa HA,El-Baz MA

更新日期：2013-01-01 00:00:00

abstract：Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...

journal_title：BioMed research international

authors： Zhou J,Xie Z,Cui P,Su Q,Zhang Y,Luo L,Li Z,Ye L,Liang H,Huang J

更新日期：2020-05-23 00:00:00

abstract：:VEGF-NO axis uncoupling is an important pathogenesis for DN. Reduced β2GPI could play a part in VEGF signaling pathway and has a protective effect on diabetic vascular disease. This study investigates the effect of reduced β2GPI on glomerular mesangial cells VEGF-NO axis uncoupling induced by high glucose. Compared to...

journal_title：BioMed research international

authors： Saijun Z,Xin L,Jie W,Shumin X,Shuaihui L,Pei Y

更新日期：2018-07-18 00:00:00

abstract：:Heavy metals have the potential to interact and induce several stress responses in the plants; thus, effects of heavy metal stress on DNA damages and total antioxidants level in Urtica dioica leaves and stems were investigated. The samples are sampled from areas with different metal exposition. Metal content was analy...

journal_title：BioMed research international

authors： Gjorgieva D,Kadifkova Panovska T,Ruskovska T,Bačeva K,Stafilov T

更新日期：2013-01-01 00:00:00

abstract：:The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 20...

journal_title：BioMed research international

authors： Guerrero-Wyss M,Durán Agüero S,Angarita Dávila L

更新日期：2018-01-09 00:00:00

abstract：:The purpose of this study was to investigate the impact of polishing methods on the bonding effectiveness and durability of different resin cements to dentin. The dentin surfaces were either treated with a fine-grit diamond bur (polishing A) or further polished by polishing disks (polishing B), and then they were bond...

journal_title：BioMed research international

authors： Ren L,Li M,Pan Y,Meng X

更新日期：2018-02-28 00:00:00

abstract：:Bacterial nanocellulose (BNC) has demonstrated a tempting prospect for applications in substitute of small blood vessels. However, present technology is inefficient in production and BNC tubes have a layered structure that may bring danger after implanting. Double oxygen-permeable silicone tubes in different diameters...

journal_title：BioMed research international

authors： Hong F,Wei B,Chen L

更新日期：2015-01-01 00:00:00

abstract：:Endothelial-to-mesenchymal transition (EndMT) emerges as an important source of fibroblasts. MicroRNA let-7 exhibits anti-EndMT effects and fibroblast growth factor (FGF) receptor has been shown to be an important in microRNA let-7 expression. The endogenous antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline (...

journal_title：BioMed research international

authors： Nagai T,Kanasaki M,Srivastava SP,Nakamura Y,Ishigaki Y,Kitada M,Shi S,Kanasaki K,Koya D

更新日期：2014-01-01 00:00:00

abstract：:Gastric cancer (GC) is one of the most common and fatal malignancies worldwide. MicroRNAs (miRNAs) play a critical role in tumor initiation, proliferation, and metastasis of gastric cancer. miR193b has been identified as a tumor suppressor in a variety of tumor types; however, its role in gastric cancer is yet to be d...

journal_title：BioMed research international

authors： Tian R,Jiang H,Shao L,Yu Y,Guo Q,Cao B,Guo S

更新日期：2020-05-25 00:00:00

abstract：BACKGROUND:Wear-related failures and instabilities are frequent failure mechanisms of total knee replacements. High-conforming designs may provide additional stability for the joint. This study analyzes the effects of a ligamentous insufficiency on the stability and the wear behavior of a high-conforming knee design. ...

journal_title：BioMed research international

authors： Reinders J,Sonntag R,Kretzer JP

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:The aims of this study were first to clearly define two different entities: locoregional recurrences and limited metastatic disease and secondly to evaluate the place of extensive surgery in these two types of recurrence. MATERIAL AND METHODS:Twenty-four patients were followed from June 2004 until May 2014....

journal_title：BioMed research international

authors： Berlière M,Duhoux FP,Taburiaux L,Lacroix V,Galant C,Leconte I,Fellah L,Lecouvet F,Bouziane D,Piette P,Lengele B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Histones play important roles in both host defenses and inflammation related to microbial infection. A peptide mimotope (SSV) was identified from a novel histone H1 monoclonal antibody (16G9 mAb) that was shown to inhibit the mixed lymphocyte reaction. In the present study, an anti-SSV producing hybridoma wa...

journal_title：BioMed research international

authors： Kusano T,Chiang KC,Inomata M,Shimada Y,Ohmori N,Goto T,Sato S,Goto S,Nakano T,Kawamoto S,Takaoka Y,Shiraishi N,Noguchi T,Kitano S

更新日期：2015-01-01 00:00:00

abstract：Background:Large scalp defects, especially those complicated by calvarial defects, titanium mesh exposure, or cerebrospinal fluid (CSF) leak, pose a challenge for the neurosurgeon and plastic surgeon. Here, we describe our experience of reconstructing the complex scalp defect with free flap transfer. Methods:From Octo...

journal_title：BioMed research international

authors： Chen F,Ju H,Huang A,Yi Y,Cao Y,Xie W,Wang X,Fu G

更新日期：2020-01-10 00:00:00

abstract：:Since 2001 the Istituto Superiore di Sanità established a quality assurance programme for molecular genetic testing that covers four pathologies: Cystic Fibrosis (CF), Beta Thalassemia (BT), Fragile X Syndrome (FX), and Familial Adenomatous Polyposis Coli (APC). Since 2009 this activity is an institutional activity an...

journal_title：BioMed research international

authors： Censi F,Tosto F,Floridia G,Marra M,Salvatore M,Baffico AM,Grasso M,Melis MA,Pelo E,Radice P,Ravani A,Rosatelli C,Resta N,Russo S,Seia M,Varesco L,Falbo V,Taruscio D

更新日期：2013-01-01 00:00:00