Culture of iPSCs Derived Pancreatic β-Like Cells In Vitro Using Decellularized Pancreatic Scaffolds: A Preliminary Trial.

abstract：:Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 an...

journal_title：BioMed research international

authors： Rzepka R,Dołęgowska B,Rajewska A,Sałata D,Budkowska M,Kwiatkowski S,Torbé A

更新日期：2016-01-01 00:00:00

abstract：:Alterations in muscle protein turnover of the unaffected side of stroke patients could contribute to physical disability. We investigated whether hypercatabolic activity occurred in unaffected arm muscle and whether supplemented essential amino acids (EAAs) could limit muscle hypercatabolism (MH). Thirty-eight dysphag...

journal_title：BioMed research international

authors： Aquilani R,Boselli M,D'Antona G,Baiardi P,Boschi F,Viglio S,Iadarola P,Pasini E,Barbieri A,Dossena M,Bongiorno AI,Verri M

更新日期：2014-01-01 00:00:00

abstract：:Following cerebral ischemia/reperfusion (I/R) injury, a series of pathophysiological processes are stimulated in both the central nervous system (CNS) and the periphery, including, but not limited to, the peripheral immune and endocrine systems and underregulation of the neuroendocrine-immune network. Glutamate (Glu) ...

journal_title：BioMed research international

authors： You J,Feng L,Xin M,Ma D,Feng J

更新日期：2018-07-19 00:00:00

abstract：:The exosomes are derived from mesenchymal stem cells (MSCs) and may be potentially used as an alternative for cell therapy, for treating diabetic wounds, and aid in angiogenesis. This study, aimed to investigate whether exosomes originated from bone marrow-derived MSCs (BMSCs) preconditioned by deferoxamine (DFO-Exos)...

journal_title：BioMed research international

authors： Ding J,Wang X,Chen B,Zhang J,Xu J

更新日期：2019-05-05 00:00:00

abstract：:The recombinant catalase-peroxidase HPI from E. coli was used as an alternative enzyme in polymerization reactions for the production of (-) epicatechin oligomers and their biological activity was characterized. The enzyme was prepared in two forms: a purified and an immobilized form. Both were tested for their activi...

journal_title：BioMed research international

authors： Di Gennaro P,Sabatini V,Fallarini S,Pagliarin R,Sello G

更新日期：2018-04-23 00:00:00

abstract：:Interest is rising for animal modeling of pathological gambling. Using the operant probabilistic-delivery task (PDT), gambling proneness can be evaluated in laboratory animals. Drawing a comparison with rats, this study evaluated the common marmoset (Callithrix jacchus) using a PDT. By nose- or hand-poking, subjects l...

journal_title：BioMed research international

authors： Zoratto F,Sinclair E,Manciocco A,Vitale A,Laviola G,Adriani W

更新日期：2014-01-01 00:00:00

abstract：:Introduction. The poor long-term adherence is known to affect the efficacy of allergen immunotherapy (AIT). In the case of injection AIT (SCIT), one of the main determinants is the inconvenience for patients to undergo prolonged build-up phases. Thus, simplifying the time schedule of the induction protocol could be ef...

journal_title：BioMed research international

authors： Caruso C,Bramé B,Bagnasco D,Cocconcelli A,Ortolani V,Pravettoni V,Scarpa S,Zisa G,Passalacqua G,Colantuono S

更新日期：2020-02-18 00:00:00

abstract：:Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour. Moreover this is a heterogeneous disease based on the tissue of origin. As CT7 and CT10 are highly expressed in cutaneous melanoma and are immunogenic in this disease, we analysed their expressi...

journal_title：BioMed research international

authors： Curioni-Fontecedro A,Pitocco R,Schoenewolf NL,Holzmann D,Soldini D,Dummer R,Calvieri S,Moch H,Mihic-Probst D,Fitsche A

更新日期：2015-01-01 00:00:00

abstract：:Background. Increased metal ion levels following total hip arthroplasty (THA) with metal-on-metal bearings are a highly debated topic. Local soft tissue reactions with chronic pain and systemic side effects such as neuropathy are described. The aim of the current study was to determine the serum metal ion concentratio...

journal_title：BioMed research international

authors： Maurer-Ertl W,Pranckh-Matzke D,Friesenbichler J,Bratschitsch G,Holzer LA,Maier M,Leithner A

更新日期：2017-01-01 00:00:00

abstract：Background:Sympathetic sprouting in the dorsal root ganglion (DRG) following nerve injuries had been proved to induce adult neuropathic pain. However, it is unclear whether the abnormal sprouting occurs in infant nerve injury. Methods:L5 spinal nerve ligation (SNL) or sham surgery was performed on adult rats and 10-da...

journal_title：BioMed research international

authors： Liu P,Zhang Q,Gao YS,Huang YG,Gao J,Zhang CQ

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:In Mexico and other developing countries, few reports of the survival of children with acute leukaemia exist. Objective. We aimed at comparing the disease-free survival of children with acute myeloid leukaemia who, in addition to being treated with the Latin American protocol of chemotherapy and an autologou...

journal_title：BioMed research international

authors： Jiménez-Hernández E,Dueñas-González MT,Arellano-Galindo J,Medrano-Ortíz-De-Zárate ME,Bekker-Méndez VC,Berges-García A,Solís-Labastida K,Sánchez-Jara B,Tiznado-García HM,Jaimes-Reyes EZ,García-Jiménez X,Espinoza-Hernández L,Núñez-

更新日期：2015-01-01 00:00:00

abstract：:Diverse high energy diets have been utilized to precipitate obesity and related metabolic disorders in rodent models, though the dietary intervention has not absolutely been standardized. The present study established usage of a customized semipurified normal control diet (NCD) and high fat diet (HFD), for research st...

journal_title：BioMed research international

authors： Sasidharan SR,Joseph JA,Anandakumar S,Venkatesan V,Ariyattu Madhavan CN,Agarwal A

更新日期：2013-01-01 00:00:00

abstract：:Cystic change in metastatic lymph nodes of papillary thyroid carcinoma (PTC) is a diagnostic challenge for fine needle aspiration (FNA) because of the scant cellularity. The aim of this study was to evaluate the measurement of thyroglobulin in fine needle aspirate (Tg-FNA) for detecting metastatic PTC in patients with...

journal_title：BioMed research international

authors： Wang Y,Zhao H,Wang YX,Wang MJ,Zhang ZH,Zhang L,Zhang B,Ahuja AT,Zhou CW,Jiang YX,Guo HQ

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to evaluate the apical microleakage of Biodentine and MTA orthograde apical plugs and to compare the effect of thickness of these biomaterials on their sealing ability. A total of eighty maxillary anterior teeth were used. The apices were removed by cutting with a diamond disc (Jota, Germany)...

journal_title：BioMed research international

authors： Bani M,Sungurtekin-Ekçi E,Odabaş ME

更新日期：2015-01-01 00:00:00

abstract：:Objective. Duodenal atresia (DA) routinely has been corrected by laparotomy and duodenoduodenostomy with excellent long-term results. We revisited the patients with DA treated in the last 12 years (2004-2016) comparing the open and the minimally invasive surgical (MIS) approach. Methods. We divided our cohort of patie...

journal_title：BioMed research international

authors： Chiarenza SF,Bucci V,Conighi ML,Zolpi E,Costa L,Fasoli L,Bleve C

更新日期：2017-01-01 00:00:00

abstract：:Accurate definition and better understanding of the mechanisms of stroke are crucial as this will guide the effective care and therapy. In this paper, we review the previous basic and clinical researches on the causes or mechanisms of ischemic cerebrovascular diseases (ICVD) and interpret the correlation between embol...

journal_title：BioMed research international

authors： Yu YP,Tan L

更新日期：2016-01-01 00:00:00

abstract：:Chronic hypoxia (CH) is characterized by long-term hypoxia that is associated with microvessel proliferation and basal membrane (BM) degradation in tissues. The IL-6/JAK2/STAT3/MMP-9 pathway has been described in a variety of human cancers and plays an essential role in microvessel proliferation and BM degradation. Th...

journal_title：BioMed research international

authors： Zhu M,Yang M,Yang Q,Liu W,Geng H,Pan L,Wang L,Ge R,Ji L,Cui S,Li Z

更新日期：2020-01-23 00:00:00

abstract：:Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...

journal_title：BioMed research international

authors： Bit A,Ghagare D,Rizvanov AA,Chattopadhyay H

更新日期：2017-01-01 00:00:00

abstract：:During a spaceflight, astronauts need to live in a spacecraft on orbit for a long time, and the relationship between humans and microorganisms in the closed environment of space is not the same as on the ground. The dynamic study of microorganisms in confined space shows that with the extension of the isolation time, ...

journal_title：BioMed research international

authors： Chen Y,Wu B,Zhang C,Fan Z,Chen Y,Xin B,Xie Q

更新日期：2020-06-20 00:00:00

abstract：Objective:To investigate the clinicopathological characteristics and risk factors in patients with lung cancer and COPD. Materials and Methods:We retrospectively reviewed the clinical data of 282 patients with lung cancer, including 174 and 108 patients with and without COPD, respectively. Information on age, sex, smo...

journal_title：BioMed research international

authors： Miao JL,Cai JJ,Qin XF,Liu RJ

更新日期：2018-02-14 00:00:00

abstract：:Epigenetic changes have major role in the normal development and programming of gene expression. Aberrant methylation results in carcinogenesis. The primary objective of our study is to determine whether primary tumor tissue and cultured tumor cells in 2D and 3D tissue culture systems have the same methylation signatu...

journal_title：BioMed research international

authors： Şükrüoğlu Erdoğan Ö,Kılıç Erciyas S,Bilir A,Buğra Tunçer Ş,Akdeniz Ödemiş D,Kurul S,Karanlık H,Cabıoğlu N,Yazıcı H

更新日期：2019-01-17 00:00:00

abstract：:In the last decade the number of wireless devices operating at the frequency band of 2.4 GHz has increased in several settings, such as healthcare, occupational, and household. In this work, the emissions from Wi-Fi transceivers applicable to context aware scenarios are analyzed in terms of potential interference and ...

journal_title：BioMed research international

authors： de Miguel-Bilbao S,Aguirre E,Lopez Iturri P,Azpilicueta L,Roldán J,Falcone F,Ramos V

更新日期：2015-01-01 00:00:00

abstract：:Background. Antitumor necrosis factor (anti-TNF) drugs have been applied for rheumatoid arthritis (RA) treatment; however, patients having anti-drug antibodies (ADAbs) do not benefit from these drugs. The meta-analysis aims to comprehensively assess the relationship between ADAb positive (ADAb+) and anti-TNF response ...

journal_title：BioMed research international

authors： Wu C,Wang S,Xian P,Yang L,Chen Y,Mo X

更新日期：2016-01-01 00:00:00

abstract：:Breast cancer is the leading cause of death in women worldwide. The search for novel compounds with antitumor activity, with less adverse effects and higher efficacy, and the development of methods to evaluate their toxicity is an area of intense research. In this study we implemented the preparation and culture of br...

journal_title：BioMed research international

authors： Carranza-Torres IE,Guzmán-Delgado NE,Coronado-Martínez C,Bañuelos-García JI,Viveros-Valdez E,Morán-Martínez J,Carranza-Rosales P

更新日期：2015-01-01 00:00:00

abstract：:The most frequently seen types of tremor are essential (ET) and parkinsonian tremor (PT) and in some patients clinical characteristics of these tremor types overlap. It is vital to distinguish between these two types of tremor in order to reach the right diagnosis and select the appropriate treatment. One of the widel...

journal_title：BioMed research international

authors： Kragelj V,Georgiev D,Pirtošek Z,Ribarič S

更新日期：2014-01-01 00:00:00

abstract：Objective:We identified differentially expressed microRNAs (DEMs) between esophageal carcinoma (ESCA) tissues and normal esophageal tissues. We then constructed a novel three-miRNA signature to predict the prognosis of ESCA patients using bioinformatics analysis. Materials and Methods. We combined two microarray profil...

journal_title：BioMed research international

authors： Wu K,Zhang C,Zhang C,Dai D

更新日期：2020-02-10 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a severe and progressive disease, a key feature of which is pulmonary vascular remodeling. Growth factors, cytokines, and lipid mediators are involved in this remodeling process. Recent reports suggest that the peroxisome proliferator-activated receptors (PPARs) play important ...

journal_title：BioMed research international

authors： Liu G,Li X,Li Y,Tang X,Xu J,Li R,Hao P,Sun Y

更新日期：2013-01-01 00:00:00

abstract：:J-proteins are molecular chaperones and present in a wide variety of organisms from prokaryote to eukaryote. Based on their domain organizations, J-proteins can be classified into 4 types, that is, Type I, Type II, Type III, and Type IV. Different types of J-proteins play distinct roles in influencing cancer propertie...

journal_title：BioMed research international

authors： Feng P,Lin H,Chen W,Zuo Y

更新日期：2014-01-01 00:00:00

abstract：:Medicinal plants have played an important role in the treatment of many diseases. Medicinal plants are believed to be well appropriate with the human body and to produce less side influences than the pharmaceuticals. Kingdom of Saudi Arabia has abundant and wide variety of medicinal plants whose therapeutic effects ha...

journal_title：BioMed research international

authors： Almalki DA,Alghamdi SA,Al-Attar AM

更新日期：2019-02-27 00:00:00

abstract：:In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic h...

journal_title：BioMed research international

authors： Muñoz C,San Francisco J,Gutiérrez B,González J

更新日期：2015-01-01 00:00:00