Identifying Potentially Avoidable Emergency Department Visits of Long-Term Care Hospital Residents in Korea: A Multicenter Retrospective Cohort Study.

abstract：:In this paper, a novel small-molecular apoptotic PET imaging probe, (18)F-ML-8 with a malonate motif structure, is presented and discussed. After study, the small tracer that belongs to a member of ApoSense family is proved to be capable of imaging merely apoptotic regions in the CTX treated tumor-bearing mice. The ex...

journal_title：BioMed research international

authors： Yao S,Hu K,Tang G,Gao S,Tang C,Yao B,Nie D,Sun T,Jiang S

更新日期：2015-01-01 00:00:00

abstract：:This study aimed at clarifying the mechanism and role of survivin in hypoxia-induced multidrug resistance (MDR) of laryngeal carcinoma cells. Human laryngeal cancer cells were incubated under hypoxia or normoxia. The expression of survivin was silenced by performing RNA interference. Additionally, by Western blot and ...

journal_title：BioMed research international

authors： Xu D,Li DW,Xie J,Chen XW

更新日期：2019-04-24 00:00:00

abstract：:The aim of the present study was to evaluate the antitumor potential of iminoflavones in in vitro and in vivo anticancer models. Preliminary screening in various cancer cell lines revealed four potential iminoflavones out of which IMF-8 was taken based on its activity against colon cancer cells. This was further confi...

journal_title：BioMed research international

authors： Prasad VG,Kawade S,Jayashree BS,Reddy ND,Francis A,Nayak PG,Kishore A,Nandakumar K,Rao CM,Shenoy RR

更新日期：2014-01-01 00:00:00

abstract：:Hydrocephalus is a common neurological condition that can have traumatic ramifications and can be lethal without treatment. Nowadays, during therapy radiologists have to spend a vast amount of time assessing the volume of cerebrospinal fluid (CSF) by manual segmentation on Computed Tomography (CT) images. Further, som...

journal_title：BioMed research international

authors： Klimont M,Flieger M,Rzeszutek J,Stachera J,Zakrzewska A,Jończyk-Potoczna K

更新日期：2019-07-07 00:00:00

abstract：PURPOSE:Thermographic assessment of temperature distribution within the examined tissues allows a quick, noncontact, noninvasive measurement of their temperature. The aim of the study was to evaluate the usefulness of digital infrared imaging in monitoring experimental inflammation of pleura (PL), lower lip (LL), and l...

journal_title：BioMed research international

authors： Całkosiński I,Dobrzyński M,Rosińczuk J,Dudek K,Chrószcz A,Fita K,Dymarek R

更新日期：2015-01-01 00:00:00

abstract：:There is mounting evidence that burnout is a risk factor for cardiovascular disease (CVD). Stress-related dysregulation of the sympathetic and parasympathetic system and the hypothalamic pituitary adrenal (HPA) axis may explain the enhanced risk for CVD. To test this hypothesis, 55 patients (34 males and 21 females) w...

journal_title：BioMed research international

authors： de Vente W,van Amsterdam JG,Olff M,Kamphuis JH,Emmelkamp PM

更新日期：2015-01-01 00:00:00

abstract：:Severe acute pancreatitis (SAP) results in high mortality. This is partly because of early multiple organ dysfunction syndromes that are usually caused by systemic inflammatory response syndrome (SIRS). Many studies have reported the beneficial effects of emodin against SAP with SIRS. However, the exact mechanism unde...

journal_title：BioMed research international

authors： Wang GJ,Wang Y,Teng YS,Sun FL,Xiang H,Liu JJ,Xia SL,Zhang GX,Chen HL,Shang D

更新日期：2016-01-01 00:00:00

abstract：:New antimicrobial properties of products derived from Humulus lupulus L. such as antiadherent and antibiofilm activities were evaluated. The growth of gram-positive but not gram-negative bacteria was inhibited to different extents by these compounds. An extract of hop cones containing 51% xanthohumol was slightly less...

journal_title：BioMed research international

authors： Rozalski M,Micota B,Sadowska B,Stochmal A,Jedrejek D,Wieckowska-Szakiel M,Rozalska B

更新日期：2013-01-01 00:00:00

abstract：:Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the lev...

journal_title：BioMed research international

authors： Zanzani SA,Gazzonis AL,Scarpa P,Berrilli F,Manfredi MT

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis. METHODS:Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneou...

journal_title：BioMed research international

authors： Akashi M,Hashikawa K,Wanifuchi S,Kusumoto J,Shigeoka M,Furudoi S,Terashi H,Komori T

更新日期：2017-01-01 00:00:00

abstract：:Peritoneal dialysis (PD) is associated with structural and functional alterations of the peritoneal membrane, consisting of fibrosis, angiogenesis, and loss of ultrafiltration capacity. Vitamin D receptor activation (VDRA) plays an important role in mineral metabolism and inflammation, but also antiangiogenic and anti...

journal_title：BioMed research international

authors： Stavenuiter AW,Farhat K,Vila Cuenca M,Schilte MN,Keuning ED,Paauw NJ,ter Wee PM,Beelen RH,Vervloet MG

更新日期：2015-01-01 00:00:00

abstract：Background:Adenosine, derived from the degradation of ATP via ectonucleotidases CD39 and CD73, is a critical immunosuppressive metabolite in the hypoxic microenvironment of tumor tissue. Adenosine signaling via A2aR can inhibit the antitumor immune response of CD8+ T cells. CD39 and CD73 high-expressing Tregs play a cr...

journal_title：BioMed research international

authors： Shi L,Feng M,Du S,Wei X,Song H,Yixin X,Song J,Wenxian G

更新日期：2019-12-14 00:00:00

abstract：:Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions. In our study, we investigated the surface expression of ICAM-1 protein and expression of ICAM-1 mRNA in cells of the monocyte/macrophage system...

journal_title：BioMed research international

authors： Paulsen K,Tauber S,Dumrese C,Bradacs G,Simmet DM,Gölz N,Hauschild S,Raig C,Engeli S,Gutewort A,Hürlimann E,Biskup J,Unverdorben F,Rieder G,Hofmänner D,Mutschler L,Krammer S,Buttron I,Philpot C,Huge A,Lier H,Barz

更新日期：2015-01-01 00:00:00

abstract：:Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...

journal_title：BioMed research international

authors： Yang J,Wang Y,Wang XY,Zhao YY,Wang J,Zhao YY

更新日期：2017-01-01 00:00:00

abstract：Purpose:Computer-aided diagnosis (CAD) can aid in improving diagnostic level; however, the main problem currently faced by CAD is that it cannot obtain sufficient labeled samples. To solve this problem, in this study, we adopt a generative adversarial network (GAN) approach and design a semisupervised learning algorith...

journal_title：BioMed research international

authors： Zheng G,Han G,Soomro NQ,Ma L,Zhang F,Zhao Y,Zhao X,Zhou C

更新日期：2019-04-15 00:00:00

abstract：:Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...

journal_title：BioMed research international

authors： Léonard B,Kridelka F,Delbecque K,Goffin F,Demoulin S,Doyen J,Delvenne P

更新日期：2014-01-01 00:00:00

abstract：:Myosin VI (MVI) is a unique motor protein moving towards the minus end of actin filaments unlike other known myosins. Its important role has recently been postulated for striated muscle and myogenic cells. Since MVI functions through interactions of C-terminal globular tail (GT) domain with tissue specific partners, w...

journal_title：BioMed research international

authors： Karolczak J,Sobczak M,Skowronek K,Rędowicz MJ

更新日期：2015-01-01 00:00:00

abstract：:As a major tumor suppressor gene, the role of PinX1 in breast cancer and its molecular mechanism remain unclear. In this study, overexpression of PinX1 was generated in 3 breast cancer cell lines, and knockdown of PinX1 was performed in a nontumorigenic breast cell line. The regulation of PinX1 on cell proliferation a...

journal_title：BioMed research international

authors： Shi R,Zhou JY,Zhou H,Zhao Z,Liang SH,Zheng WL,Ma WL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Cost sharing between beneficiaries and government is critical to attain universal health coverage. The government of Ethiopia introduced social health insurance to improve access to quality health services. Hence, HCP are the ultimate frontline service provider; their WTP for health insurance could influence...

journal_title：BioMed research international

authors： Mekonne A,Seifu B,Hailu C,Atomsa A

更新日期：2020-04-14 00:00:00

abstract：:Translocations are the most common type of structural chromosomal abnormalities. Unbalanced translocations are usually found in children who present with congenital abnormalities, developmental delay, or intellectual disability. Balanced translocations are usually found in adults who frequently present with reproducti...

journal_title：BioMed research international

authors： Paththinige CS,Sirisena ND,Kariyawasam UGIU,Dissanayake VHW

更新日期：2019-04-02 00:00:00

abstract：:Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...

journal_title：BioMed research international

authors： Xu C,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this study was to establish an acid-etching procedure for altering the Ca/P ratio of the nanostructured surface of hydroxyapatite (HAP) by using surface chemical and morphological analyses (XPS, XRD, SEM, surface roughness, and wettability) and to evaluate the in vitro response of osteoblast-like cells ...

journal_title：BioMed research international

authors： Abe Y,Okazaki Y,Hiasa K,Yasuda K,Nogami K,Mizumachi W,Hirata I

更新日期：2013-01-01 00:00:00

abstract：Purpose:To investigate the pachymetry distribution of central cornea and morphologic changes in subclinical keratoconus with normal biomechanics and determine their potential benefit for the screening of very early keratoconus. Methods:This retrospective comparative study was performed in 33 clinically unaffected eyes...

journal_title：BioMed research international

authors： Song P,Yang K,Li P,Liu Y,Liang D,Ren S,Zeng Q

更新日期：2019-11-19 00:00:00

abstract：Objective:It is sometimes difficult to obtain complete/partial response of large hepatocellular carcinoma (HCC) nodules by trans-arterial chemoembolization/embolization (TACE/TAE). The aim is retrospective investigation of tumor response of large HCC nodules (>7 cm) treated by the new TACE technique, repeated alternate...

journal_title：BioMed research international

authors： Irie T,Takahashi N,Kamoshida T,Kashimura J,Ariga H

更新日期：2020-01-19 00:00:00

abstract：:Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mechanisms of action. ...

journal_title：BioMed research international

authors： Liang B,He X,Zhao YX,Zhang XX,Gu N

更新日期：2020-07-07 00:00:00

abstract：:Falls are an important health concern among older adults due to age-related changes in the body. Having a medical history of chronic health condition may pose even higher risk of falling. Only few studies have assessed a number of chronic health conditions as risk factor for falls over a large nationally representativ...

journal_title：BioMed research international

authors： Paliwal Y,Slattum PW,Ratliff SM

更新日期：2017-01-01 00:00:00

abstract：:Selenium is an essential trace element, which has certain antioxidant properties. Na2SeO3 is toxic, and its use is limited. SeMet, as an organic selenium, is less toxic than Na2SeO3. In this experiment, different concentrations of Na2SeO3 and SeMet were added to MEA and PDA media to observe the effect of selenium on t...

journal_title：BioMed research international

authors： Zhao W,Zhai F,Han J

更新日期：2020-04-26 00:00:00

abstract：:The endoscopic and histopathological findings detected in Sparus aurata experimentally infected with third-stage Anisakis larvae without intermediate host are evaluated and discussed. In six fish, live nematode larvae were introduced by gastroscopy into the stomach. The first observation by endoscope, 15 days after ch...

journal_title：BioMed research international

authors： Marino F,Lanteri G,Passantino A,De Stefano C,Costa A,Gaglio G,Macrì F

更新日期：2013-01-01 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：:Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...

journal_title：BioMed research international

authors： Veryser L,Bracke N,Wynendaele E,Joshi T,Tatke P,Taevernier L,De Spiegeleer B

更新日期：2016-01-01 00:00:00