A novel anti-histone H1 monoclonal antibody, SSV monoclonal antibody, improves lung injury and survival in a mouse model of lipopolysaccharide-induced sepsis-like syndrome.

abstract：:Tuberculosis (TB) is a dangerous infectious disease characterized by a tight interplay between mycobacteria and host cells in granulomatous lesions (granulomas) during the latent, asymptomatic stage of infection. Mycobacterium-host cell relationships were analyzed in granulomas obtained from various organs of BALB/c m...

journal_title：BioMed research international

authors： Ufimtseva E

更新日期：2015-01-01 00:00:00

abstract：:Introduction. This study aimed to evaluate the effects of resorbable blasting media (RBM) treatment on early stability of orthodontic mini-implants by mechanical, histomorphometric, and histological analyses. Methods. Ninety-six (64 for mechanical study and 32 for histological study and histomorphometric analysis) tit...

journal_title：BioMed research international

authors： Gansukh O,Jeong JW,Kim JW,Lee JH,Kim TW

更新日期：2016-01-01 00:00:00

abstract：:Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, and appendiceal mucosae. Oral mucosa grafts, especially buccal muco...

journal_title：BioMed research international

authors： Xiong S,Wang J,Zhu W,Yang K,Ding G,Li X,Eun DD

更新日期：2020-07-27 00:00:00

abstract：:Objective. To confirm that physical activity program improves the symptoms of dementia and the most effective physical activity was selected to help establish exercise programs. Methods. Three databases, PubMed, Science Direct, and Willey online, were used to collect articles. The databases were published between Janu...

journal_title：BioMed research international

authors： Lee HS,Park SW,Park YJ

更新日期：2016-01-01 00:00:00

abstract：:Objective. This study was aimed at analyzing the expressions of long noncoding RNAs (lncRNAs) in Botulinum Toxin Type A (BoNTA) treated human dermal fibroblasts (HDFs) in vitro. Methods. We used RNA sequencing to characterize the lncRNAs and mRNAs transcriptome in the control and BoNTA treated group, in conjunction wi...

journal_title：BioMed research international

authors： Miao YY,Liu J,Zhu J,Tao YL,Zhang JA,Luo D,Zhou BR

更新日期：2017-01-01 00:00:00

abstract：:This study aimed to evaluate the genes that were expressed in the healing bones around SLA-treated titanium orthodontic mini-implants in a beagle at early (1-week) and late (4-week) stages with RNA-sequencing (RNA-Seq). Samples from sites of surgical defects were used as controls. Total RNA was extracted from the tiss...

journal_title：BioMed research international

authors： Nahm KY,Heo JS,Lee JH,Lee DY,Chung KR,Ahn HW,Kim SH

更新日期：2015-01-01 00:00:00

abstract：:Iodinated contrast (IC) is clinically used in diagnostic and interventional procedures, but its use can result in contrast-induced acute kidney injury (CI-AKI). Chronic kidney disease (CKD) and chronic hyperglycemia (CH) are important predisposing factors to CI-AKI. The aim of this study was to investigate the impact ...

journal_title：BioMed research international

authors： Fernandes SM,Martins DM,da Fonseca CD,Watanabe M,Vattimo Mde F

更新日期：2016-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is associated with an increased risk of developing advanced chronic kidney disease (CKD). Yet, effective interventions to prevent this conversion are unavailable for clinical practice. In this study, we examined the beneficial effects of Tanshinone IIA on renal fibrosis in a mouse model of fo...

journal_title：BioMed research international

authors： Jiang C,Shao Q,Jin B,Gong R,Zhang M,Xu B

更新日期：2015-01-01 00:00:00

abstract：:Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases an...

journal_title：BioMed research international

authors： Ponomarenko P,Rasskazov D,Suslov V,Sharypova E,Savinkova L,Podkolodnaya O,Podkolodny NL,Tverdokhleb NN,Chadaeva I,Ponomarenko M,Kolchanov N

更新日期：2016-01-01 00:00:00

abstract：:ADP-glucose pyrophosphorylase (AGPase) is the first rate limiting enzyme of starch biosynthesis pathway and has been exploited as the target for greater starch yield in several plants. The structure-function analysis and substrate binding specificity of AGPase have provided enormous potential for understanding the rol...

journal_title：BioMed research international

authors： Sarma K,Sen P,Barooah M,Choudhury MD,Roychoudhury S,Modi MK

更新日期：2014-01-01 00:00:00

abstract：OBJECT:The aim of this report was to explore the clinical presentation, radiological features, treatment methods, and outcome of micro-AVMs presenting with intracerebral hemorrhage. METHODS:The clinical data, radiological features, treatment, and follow-up results for a consecutive series of 13 cases with micro-AVMs w...

journal_title：BioMed research international

authors： Hong JF,Song YF,Liu HB,Liu Z,Wang SS

更新日期：2015-01-01 00:00:00

abstract：:Objective. To evaluate the efficacy of bundle intervention on healthcare-associated (HA) methicillin-resistant Staphylococcus Aureus (MRSA) infection in the neonatal intensive care unit (NICU). Methods. In this study, 11,277 infants having undergone treatment at the NICU in Xiamen, China, from January 2014 to February...

journal_title：BioMed research international

authors： Huang H,Ran J,Yang J,Li P,Zhuang G

更新日期：2019-07-10 00:00:00

abstract：:The present study was proposed to investigate the toxicological and prophylactic potential of ethanolic extracts of Rosa damascena and Nymphaea alba and their mixture in albino mice. For toxicity study, three different doses of plant extracts were orally administrated to three groups of mice for 14 successive days. Bl...

journal_title：BioMed research international

authors： Batool R,Kalsoom A,Akbar I,Arshad N,Jamil N

更新日期：2018-01-23 00:00:00

abstract：:Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the lev...

journal_title：BioMed research international

authors： Zanzani SA,Gazzonis AL,Scarpa P,Berrilli F,Manfredi MT

更新日期：2014-01-01 00:00:00

abstract：:Liver regeneration after partial hepatectomy (PH) is a highly orchestrated biological process in which synchronized hepatocyte proliferation is induced after massive liver mass loss. Hepatocyte proliferation could be regulated by multiple signals, such as miRNAs and autophagy, but underlying mechanism remains unclear....

journal_title：BioMed research international

authors： Lu T,Hao J,Shen C,Gu G,Zhang J,Xu N

更新日期：2018-07-31 00:00:00

abstract：:Contrast-induced nephropathy (CIN) remains a leading cause of iatrogenic acute kidney injury, as the usage of contrast media for imaging and intravascular intervention keeps expanding. Diabetes is an important predisposing factor for CIN, particularly in patients with renal functional impairment. Renal hypoxia, combin...

journal_title：BioMed research international

authors： Heyman SN,Rosenberger C,Rosen S,Khamaisi M

更新日期：2013-01-01 00:00:00

abstract：Background and Aims:Contrast-induced nephropathy (CIN) is a relatively infrequent complication after percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). However, little is known about the association between cytochrome c (cyt c) and increased risk of CIN. We conducted t...

journal_title：BioMed research international

authors： Tang C,Hou J,Yan G,Qiao Y,Wang D,Zhu B,Liu B,Luo E,Nawabi AQ,Chen L

更新日期：2019-01-23 00:00:00

abstract：Background:In vitro fertilization and embryo transfer (IVF-ET) technology has been widely used in the therapy of refractory infertility. Previous studies showed that acupuncture can effectively increase the clinical pregnancy rate of IVF-ET. However, the molecular mechanism is unknown. Materials and Methods:In this st...

journal_title：BioMed research international

authors： Cheng J,Jin X,Shen J,Mu Y,Li Q,Xia L,Gao Y,Xia Y

更新日期：2019-05-28 00:00:00

abstract：:Cerebral malaria (CM) is a severe complication of and a leading cause of death due to Plasmodium falciparum infection. CM is likely the result of interrelated events, including mechanical obstruction due to parasite sequestration in the microvasculature, and upregulation of Th1 immune responses. In parallel, blood-bra...

journal_title：BioMed research international

authors： Guo J,Waknine-Grinberg JH,Mitchell AJ,Barenholz Y,Golenser J

更新日期：2014-01-01 00:00:00

abstract：:Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain. It has not been fully examined yet how nerve conduction inhibitions by l...

journal_title：BioMed research international

authors： Uemura Y,Fujita T,Ohtsubo S,Hirakawa N,Sakaguchi Y,Kumamoto E

更新日期：2014-01-01 00:00:00

abstract：AIM:Gastrointestinal mucositis is a frequent complication of antineoplastic chemotherapy, but the effects of chemotherapy on mucosal defense mechanisms remain poorly understood. We studied the effects of cisplatin on mucin, one of the principal defense factors of the gastrointestinal mucosa, and evaluated the efficacy ...

journal_title：BioMed research international

authors： Yamamoto H,Ishihara K,Takeda Y,Koizumi W,Ichikawa T

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to assess the diagnostic accuracy of subjective ultrasound evaluation of myometrial invasion of endometrial cancer and to compare its accuracy to objective methods. All consecutive patients with histologically proven endometrial cancer, who underwent ultrasound evaluation followed by surgical...

journal_title：BioMed research international

authors： Frühauf F,Zikan M,Semeradova I,Dundr P,Nemejcova K,Dusek L,Cibula D,Fischerova D

更新日期：2017-01-01 00:00:00

abstract：Background:The aim of our study was to investigate the impact of abdominal wall reconstruction surgery on tissue anatomy and to explore how flap surgery influences the patient's immune status. Methods:Experimental abdominal wall defects were created in 8 Sus scrofa (swine) animal models. The animals were divided into ...

journal_title：BioMed research international

authors： Popa F,Georgescu AV

更新日期：2017-01-01 00:00:00

abstract：:Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred mo...

journal_title：BioMed research international

authors： Shahidi M,Phillips RA,Chik CL

更新日期：2019-03-13 00:00:00

abstract：:The purpose of the study is to evaluate the relationship between NIH-CPSI and IIEF-5 in Chinese men with CP/CPPS. A large cross-sectional and multicenter survey was conducted from July 2012 to January 2014. Men were recruited from urology clinics which were located at the five cities in China. All men participated in ...

journal_title：BioMed research international

authors： Gao J,Gao P,Hao Z,Zhou Z,Liu J,Li H,Xing J,Zhou Z,Deng C,Deng L,Wei Q,Zhang X,Zhou J,Fan S,Tai S,Yang C,Shi K,Huang Y,Ye Z,Liang C

更新日期：2015-01-01 00:00:00

abstract：:Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β signaling in DN is...

journal_title：BioMed research international

authors： Zhou X,Gao C,Huang W,Yang M,Chen G,Jiang L,Gou F,Feng H,Ai N,Xu Y

更新日期：2014-01-01 00:00:00

abstract：:More than one-third of the world's population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease. The severity of the disease is strongly...

journal_title：BioMed research international

authors： Salazar-Castañon VH,Legorreta-Herrera M,Rodriguez-Sosa M

更新日期：2014-01-01 00:00:00

abstract：:Autophagic elements typically appear as spherical bodies. During their life they undergo a series of changes (e.g., fusion, degradation of content, and swelling) which influence their size in a way that may be characteristic for cell type, stage of maturation, or various experimentally manipulated parameters. A simple...

journal_title：BioMed research international

authors： Kovács AL

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:Ehlers-Danlos syndrome hypermobility type a. k. a. joint hypermobility syndrome (JHS/EDS-HT) is a hereditary musculoskeletal disorder associating generalized joint hypermobility with chronic pain. Anecdotal reports suggest a prominent role for kinesiophobia in disease manifestations, but no study has systema...

journal_title：BioMed research international

authors： Celletti C,Castori M,La Torre G,Camerota F

更新日期：2013-01-01 00:00:00

abstract：:After decades of intensive searching for antimicrobial compounds derived from actinobacteria, the frequency of isolation of new molecules has decreased. To cope with this concern, studies have focused on the exploitation of actinobacteria from unexplored environments and actinobacteria symbionts of plants and animals....

journal_title：BioMed research international

authors： Mendes TD,Borges WS,Rodrigues A,Solomon SE,Vieira PC,Duarte MC,Pagnocca FC

更新日期：2013-01-01 00:00:00