Reduction of experimental cerebral malaria and its related proinflammatory responses by the novel liposome-based β-methasone nanodrug.

abstract：:DNA-binding proteins often play important role in various processes within the cell. Over the last decade, a wide range of classification algorithms and feature extraction techniques have been used to solve this problem. In this paper, we propose a novel DNA-binding protein prediction method called HMMBinder. HMMBinde...

journal_title：BioMed research international

authors： Zaman R,Chowdhury SY,Rashid MA,Sharma A,Dehzangi A,Shatabda S

更新日期：2017-01-01 00:00:00

abstract：:Lung illness encountered in patients with rheumatic diseases bears clinical significance in terms of increased morbidity and mortality as well as potential challenges placed on patient care. Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accum...

journal_title：BioMed research international

authors： Ha YJ,Lee YJ,Kang EH

更新日期：2018-05-08 00:00:00

abstract：INTRODUCTION:Spectroscopic analysis of urine samples from laboratory animals can be used to predict the efficacy and side effects of drugs. This employs methods combining (1)H NMR spectroscopy with quantification of biomarkers or with multivariate data analysis. The most critical steps in data evaluation are analytical...

journal_title：BioMed research international

authors： Schreier C,Kremer W,Huber F,Neumann S,Pagel P,Lienemann K,Pestel S

更新日期：2013-01-01 00:00:00

abstract：:Natural medical plant is considered as a good source of tyrosinase inhibitors. Red vine leaf extract (RVLE) can be applied to a wide variety of medical disciplines, such as treatments for chronic venous insufficiency over many decades. This study investigated the tyrosinase inhibitory activity of RVLE containing galli...

journal_title：BioMed research international

authors： Lin YS,Chen HJ,Huang JP,Lee PC,Tsai CR,Hsu TF,Huang WY

更新日期：2017-01-01 00:00:00

abstract：:This study was conducted to show the effect of Aspergillus awamori (AA), fructooligosaccharide (FOS), and combined Aspergillus awamori and fructooligosaccharide (AA + FOS) on growth, digestibility, blood parameters, and expression of some growth-related genes. A total of 60 broiler chicks at the age of 15 d were divid...

journal_title：BioMed research international

authors： Saleh AA,Amber K,El-Magd MA,Atta MS,Mohammed AA,Ragab MM,Abd El-Kader H

更新日期：2014-01-01 00:00:00

abstract：:We have analyzed anatomic variations in the pectoralis major and pectoralis minor muscles of common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) and compared them to anatomic variations in these muscles in humans (Homo sapiens). We have macroscopically dissected these muscles in six adult Pan troglodytes, ...

journal_title：BioMed research international

authors： Potau JM,Arias-Martorell J,Bello-Hellegouarch G,Casado A,Pastor JF,de Paz F,Diogo R

更新日期：2018-01-21 00:00:00

abstract：Objectives:Magnetic resonance imaging (MRI) and in particular diffusion-weighted imaging (DWI) have been broadly proven to be the reference imaging method to discriminate between cholesteatoma and noncholesteatomatous middle ear lesions, especially when high tissue specificity is required. The aim of this study is to d...

journal_title：BioMed research international

authors： Russo C,Elefante A,Di Lullo AM,Carotenuto B,D'Amico A,Cavaliere M,Iengo M,Brunetti A

更新日期：2018-04-24 00:00:00

abstract：BACKGROUND:Cost sharing between beneficiaries and government is critical to attain universal health coverage. The government of Ethiopia introduced social health insurance to improve access to quality health services. Hence, HCP are the ultimate frontline service provider; their WTP for health insurance could influence...

journal_title：BioMed research international

authors： Mekonne A,Seifu B,Hailu C,Atomsa A

更新日期：2020-04-14 00:00:00

abstract：:Lung cancer is a leading cause of death worldwide. Currently, in differential diagnosis of lung cancer, accurate classification of cancer types (adenocarcinoma, squamous cell carcinoma, and small cell carcinoma) is required. However, improving the accuracy and stability of diagnosis is challenging. In this study, we d...

journal_title：BioMed research international

authors： Teramoto A,Tsukamoto T,Kiriyama Y,Fujita H

更新日期：2017-01-01 00:00:00

abstract：:In the biomedical field, there is growing interest in using human stem cell-derived neurons as in vitro models for pharmacological and toxicological screening of bioactive compounds extracted from natural products. Lignosus rhinocerus (Tiger Milk Mushroom) is used by indigenous communities in Malaysia as a traditional...

journal_title：BioMed research international

authors： Yeo Y,Tan JBL,Lim LW,Tan KO,Heng BC,Lim WL

更新日期：2019-08-19 00:00:00

abstract：:Little is known about how prenatal maternal stress (PNMS) influences risks of asthma in humans. In this small study, we sought to determine whether disaster-related PNMS would predict asthma risk in children. In June 1998, we assessed severity of objective hardship and subjective distress in women pregnant during the ...

journal_title：BioMed research international

authors： Turcotte-Tremblay AM,Lim R,Laplante DP,Kobzik L,Brunet A,King S

更新日期：2014-01-01 00:00:00

abstract：:The aim of this population-based cohort study was to explore postoperative renal outcomes of patients receiving pyelolithotomy versus percutaneous nephrolithotomy (PCNL). Data were retrieved from the Taiwan National Health Insurance Research Database. During the period from Jan 1, 1998, to Dec 31, 2012, there were 254...

journal_title：BioMed research international

authors： Chen FT,Liu FC,Cheng CW,Lin JR,Yu HP

更新日期：2018-05-02 00:00:00

abstract：:Cerenkov luminescence imaging (CLI) can provide information of medical radionuclides used in nuclear imaging based on Cerenkov radiation, which makes it possible for optical means to image clinical radionuclide labeled probes. However, the exceptionally weak Cerenkov luminescence (CL) from Cerenkov radiation is suscep...

journal_title：BioMed research international

authors： Cao X,Li Y,Zhan Y,Chen X,Kang F,Wang J,Liang J

更新日期：2016-01-01 00:00:00

abstract：:Mitochondrial heat shock proteins, such as HSP60, are chaperones responsible for the folding, transport, and quality control of mitochondrial matrix proteins and are essential for maintaining life. Both prosurvival and proapoptotic roles have been proposed for HSP60, and HSP60 is reportedly involved in the initiation ...

journal_title：BioMed research international

authors： Chen TH,Liu SW,Chen MR,Cho KH,Chen TY,Chu PH,Kao YY,Hsu CH,Lin KM

更新日期：2015-01-01 00:00:00

abstract：:Chronic hypoxia (CH) is characterized by long-term hypoxia that is associated with microvessel proliferation and basal membrane (BM) degradation in tissues. The IL-6/JAK2/STAT3/MMP-9 pathway has been described in a variety of human cancers and plays an essential role in microvessel proliferation and BM degradation. Th...

journal_title：BioMed research international

authors： Zhu M,Yang M,Yang Q,Liu W,Geng H,Pan L,Wang L,Ge R,Ji L,Cui S,Li Z

更新日期：2020-01-23 00:00:00

abstract：:Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried ur...

journal_title：BioMed research international

authors： Frati ER,Martinelli M,Fasoli E,Colzani D,Bianchi S,Binda S,Olivani P,Tanzi E

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Promoting participation in sport organizations may be a population strategy for preventing falls in older people. In this study, we examined whether participation in sport organizations is associated with fewer falls in older people even after adjusting for multiple individual and environmental factors. METH...

journal_title：BioMed research international

authors： Hayashi T,Kondo K,Suzuki K,Yamada M,Matsumoto D

更新日期：2014-01-01 00:00:00

abstract：:Periodontal remodeling and alveolar bone resorption and formation play essential roles during orthodontic tooth movement (OTM). In the process, human periodontal ligament cells (HPDLCs) sense and respond to orthodontic forces, contributing to the alveolar bone formation. However, the underlying mechanism in this proce...

journal_title：BioMed research international

authors： Yang Y,Wang BK,Chang ML,Wan ZQ,Han GL

更新日期：2018-11-05 00:00:00

abstract：Purpose:High tibial osteotomy (HTO) has been adopted as an effective surgery for medial degeneration of the osteoarthritis (OA) knee. However, satisfactory outcomes necessitate the precise creation and distraction of osteotomized wedges and the use of intraoperative X-ray images to continually monitor the wedge-related...

journal_title：BioMed research international

authors： Yang JC,Chen CF,Luo CA,Chang MC,Lee OK,Huang Y,Lin SC

更新日期：2018-05-08 00:00:00

abstract：Objective:Delays in skeletal maturity are related to bone mass and fracture risk in children, but the factors that determine it are unknown. We aimed to identify the association between insulin-like growth factor-1 (IGF-1) and skeletal maturation before and after growth hormone (GH) treatment. Methods:In this retrospe...

journal_title：BioMed research international

authors： Zhao Q,Zhang M,Chu Y,Ji B,Pan H,Sun H,Ban B

更新日期：2020-08-13 00:00:00

abstract：Objective:To explore multiscale integrated analysis methods in identifying key regulators of esophageal cancer (ESCA). Methods:We downloaded the ESCA dataset from The Cancer Genome Atlas (TCGA) database, which contained RNA-seq data, miRNA-seq data, methylation data, and clinical phenotype information. Then, we combin...

journal_title：BioMed research international

authors： Xu Z,Wu Z,Zhang J,Zhou R,Wu J,Yu B

更新日期：2020-08-12 00:00:00

abstract：:Helicobacter pylori colonization of gastric mucosa causes pain of unknown etiology in about 15-20% of infected subjects. The aim of the present work was to determine the level of expression of enzymes involved in the synthesis of melatonin in gastric mucosa of asymptomatic and symptomatic H. pylori infected patients. ...

journal_title：BioMed research international

authors： Chojnacki C,Popławski T,Blasiak J,Chojnacki J,Reiter RJ,Klupinska G

更新日期：2013-01-01 00:00:00

abstract：:This study evaluated the efficacy and safety of pulmonary rehabilitation (PR) for pneumoconiosis. We systematically searched PubMed, Embase, The Cochrane Library, Web of Science, SinoMed, CNKI, VIP databases and Wanfang Data from their inception to June 1, 2019. A systematic review and meta-analysis of randomized cont...

journal_title：BioMed research international

authors： Zhao H,Xie Y,Wang J,Li X,Li J

更新日期：2020-07-28 00:00:00

abstract：:L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is primarily due to enzymatic activity, but other mechanisms have been proposed recently which require further investigation. L-amino acid oxidases ex...

journal_title：BioMed research international

authors： Izidoro LF,Sobrinho JC,Mendes MM,Costa TR,Grabner AN,Rodrigues VM,da Silva SL,Zanchi FB,Zuliani JP,Fernandes CF,Calderon LA,Stábeli RG,Soares AM

更新日期：2014-01-01 00:00:00

abstract：:The availability of an active substance through the skin depends basically on two consecutive steps: the release of this substance from the vehicle and its subsequent permeation through the skin. Hence, studies on the specific properties of vehicles, such as their rheological behavior, are of great interest in the fie...

journal_title：BioMed research international

authors： Isaac VL,Chiari-Andréo BG,Marto JM,Moraes JD,Leone BA,Corrêa MA,Ribeiro HM

更新日期：2015-01-01 00:00:00

abstract：:Calcium phosphate cement (CPC) has good release efficiency and has therefore been used as a drug delivery system for postoperative infection. The release profile of CPC has mainly been evaluated by in vitro studies, which are carried out by immersing test specimens in a relatively large amount of solvent. However, it ...

journal_title：BioMed research international

authors： Uchida K,Sugo K,Nakajima T,Nakawaki M,Takano S,Nagura N,Takaso M,Urabe K

更新日期：2018-05-15 00:00:00

abstract：:Osteoarthritis (OA) is one of the most common debilitating disorders among the elderly population. At present, there is no definite cure for the underlying causes of OA. However, adipose tissue-derived stem cells (ADSCs) in the form of stromal vascular fraction (SVF) may offer an alternative at this time. ADSCs are on...

journal_title：BioMed research international

authors： Pak J,Lee JH,Kartolo WA,Lee SH

更新日期：2016-01-01 00:00:00

abstract：Objectives:Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han...

journal_title：BioMed research international

authors： Yang S,Li K,Zhu MM,Yuan XD,Jiao XL,Yang YY,Li J,Li L,Zhang HN,Du YH,Wei YX,Qin YW

更新日期：2019-10-13 00:00:00

abstract：:This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic pre...

journal_title：BioMed research international

authors： Shen J,Shen J,Huang K,Wu Y,Pan J,Zhan R

更新日期：2019-03-19 00:00:00

abstract：:Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

journal_title：BioMed research international

authors： Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

更新日期：2015-01-01 00:00:00