Abstract:
UNLABELLED:Ehlers-Danlos syndrome hypermobility type a. k. a. joint hypermobility syndrome (JHS/EDS-HT) is a hereditary musculoskeletal disorder associating generalized joint hypermobility with chronic pain. Anecdotal reports suggest a prominent role for kinesiophobia in disease manifestations, but no study has systematically addressed this point. OBJECTIVE:To investigate the impact of kinesiophobia and its relationship with pain, fatigue, and quality of life in JHS/EDS-HT. DESIGN:Cross-sectional study. SUBJECTS/PATIENTS:42 patients (40 female and 2 male) with JHS/EDS-HT diagnosis following standardized diagnostic criteria were selected. METHODS:Disease features were analyzed by means of specific questionnaires and scales evaluating kinesiophobia, pain, fatigue, and quality of life. The relationships among variables were investigated using the Spearman bivariate analysis. RESULTS:Kinesiophobia resulted predominantly in the patients' sample. The values of kinesiophobia did not correlate with intensity of pain, quality of life, and (or) the single component of fatigue. A strong correlation was discovered between kinesiophobia and general severity of fatigue. CONCLUSIONS:In JHS/EDS-HT, the onset of pain-avoiding strategies is related to the presence of pain but not to its intensity. The clear-cut correlation between kinesiophobia and severity of fatigue suggests a direct link between musculoskeletal pain and fatigue. In JHS/EDS-HT, the underlying mechanism is likely to be facilitated by primary disease characteristics, including hypotonia.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Celletti C,Castori M,La Torre G,Camerota Fdoi
10.1155/2013/580460subject
Has Abstractpub_date
2013-01-01 00:00:00pages
580460eissn
2314-6133issn
2314-6141journal_volume
2013pub_type
杂志文章abstract:Objective:To analyse the short-term adverse effects (AEs) of propranolol in the treatment of infantile hemangiomas (IHs) and their relevant factors, as well as the relationship between child growth and propranolol. Methods:A total of 506 patients with confirmed or suspected IHs were enrolled, and a total of 439 cases ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2728952
更新日期:2019-11-25 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/481621
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8680935
更新日期:2019-04-14 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2018-11-05 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/913696
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/405860
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9742765
更新日期:2019-05-05 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2020-04-14 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章,已发布勘误
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journal_title:BioMed research international
pub_type: 已发布勘误
doi:10.1155/2016/1235429
更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1155/2016/9846823
更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1155/2015/612352
更新日期:2015-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 已发布勘误
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更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2013/340513
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/618382
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-08-25 00:00:00
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pub_type: 杂志文章
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更新日期:2020-03-11 00:00:00
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更新日期:2019-04-15 00:00:00
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更新日期:2020-03-24 00:00:00
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pub_type: 杂志文章
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