Impact of MRSA Transmission and Infection in a Neonatal Intensive Care Unit in China: A Bundle Intervention Study during 2014-2017.

Abstract:

:Objective. To evaluate the efficacy of bundle intervention on healthcare-associated (HA) methicillin-resistant Staphylococcus Aureus (MRSA) infection in the neonatal intensive care unit (NICU). Methods. In this study, 11,277 infants having undergone treatment at the NICU in Xiamen, China, from January 2014 to February 2017 were recruited. We retrospectively reviewed patients' demographic and clinical information. Patients from 2014 to 2015 were treated as the control group and those from 2016 to 2017 were classified as the experimental group. Bundle intervention measures were performed, including screening for MRSA, isolation precautions, training of hand hygiene, cleaning protocols, and decontamination of isolation ward. The HA-MRSA data and compliance of infection control measures between both groups were analyzed. Results. Through bundle interventions, the compliance with the isolation of MRSA raised from 55.88% to 92.86% and hand hygiene compliance increased from 90.07% to 93.23% (P < 0.05). The HA infection decreased from 1.87% to 1.71% (P > 0.05) and HA detection rate of MRSA declined from 2.63‰ to 1.00‰, respectively (P < 0.05). Conclusion. Multifaceted interventions can effectively prevent MRSA infection and transmission; this includes active surveillance, isolation precautions, increased hand hygiene compliance, environmental cleaning, and decontamination.

journal_name

Biomed Res Int

authors

Huang H,Ran J,Yang J,Li P,Zhuang G

doi

10.1155/2019/5490413

subject

Has Abstract

pub_date

2019-07-10 00:00:00

pages

5490413

eissn

2314-6133

issn

2314-6141

journal_volume

2019

pub_type

杂志文章
  • Comparison of Malated Ringer's with Two Other Balanced Crystalloid Solutions in Resuscitation of Both Severe and Moderate Hemorrhagic Shock in Rats.

    abstract::In preclinical treatment of polytraumatized patients crystalloids are preferentially used. To avoid metabolic acidosis, metabolizable anions like lactate or acetate are used to replace chloride in these solutions. We here studied the effects of malated Ringer's in resuscitation of both shock severities in comparison t...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/151503

    authors: Keitel J,Hussmann B,Lendemans S,de Groot H,Rohrig R

    更新日期:2015-01-01 00:00:00

  • Zoonotic Gastrointestinal Parasites of Baboons (Papio anubis) in the Shai Hill Reserve in Ghana.

    abstract::Several intestinal parasites of baboons are of zoonotic importance, especially where there is considerable interaction between the baboons and humans. The identification of gastrointestinal parasite infections of baboons (Papio anubis) was undertaken at the Shai Hills Reserve Resort, Ghana. A total of 51 faecal sample...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/1083251

    authors: Larbi JA,Akyeampong S,Abubakari A,Offei Addo S,Okoto D,Hanson H

    更新日期:2020-03-11 00:00:00

  • Distinct action of flavonoids, myricetin and quercetin, on epithelial Cl⁻ secretion: useful tools as regulators of Cl⁻ secretion.

    abstract::Epithelial Cl(-) secretion plays important roles in water secretion preventing bacterial/viral infection and regulation of body fluid. We previously suggested that quercetin would be a useful compound for maintaining epithelial Cl(-) secretion at a moderate level irrespective of cAMP-induced stimulation. However, we n...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/902735

    authors: Sun H,Niisato N,Nishio K,Hamilton KL,Marunaka Y

    更新日期:2014-01-01 00:00:00

  • Heat shock protein 90 in Alzheimer's disease.

    abstract::Alzheimer's disease (AD) is the first most common neurodegenerative disease. Despite a large amount of research, the pathogenetic mechanism of AD has not yet been clarified. The two hallmarks of the pathology of AD are the extracellular senile plaques (SPs) of aggregated amyloid-beta (Aβ) peptide and the accumulation ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/796869

    authors: Ou JR,Tan MS,Xie AM,Yu JT,Tan L

    更新日期:2014-01-01 00:00:00

  • An Overview of Lipid Metabolism and Nonalcoholic Fatty Liver Disease.

    abstract::The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or indirectly contribute to NAFLD, especially fatty acid accumulation, arachidonic acid metabolic disturbance, and ceramide overload. The effects o...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/4020249

    authors: Pei K,Gui T,Kan D,Feng H,Jin Y,Yang Y,Zhang Q,Du Z,Gai Z,Wu J,Li Y

    更新日期:2020-07-18 00:00:00

  • The role of neurotrophic factors conjugated to iron oxide nanoparticles in peripheral nerve regeneration: in vitro studies.

    abstract::Local delivery of neurotrophic factors is a pillar of neural repair strategies in the peripheral nervous system. The main disadvantage of the free growth factors is their short half-life of few minutes. In order to prolong their activity, we have conjugated to iron oxide nanoparticles three neurotrophic factors: nerve...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/267808

    authors: Ziv-Polat O,Shahar A,Levy I,Skaat H,Neuman S,Fregnan F,Geuna S,Grothe C,Haastert-Talini K,Margel S

    更新日期:2014-01-01 00:00:00

  • Nutritional risk factors for age-related macular degeneration.

    abstract:PURPOSE:To evaluate the role of nutritional factors, serum lipids, and lipoproteins in late age-related macular degeneration (late AMD). METHODS:Intake of red meat, fruit, fish, vegetables, and alcohol, smoking status, and body mass index (BMI) were ascertained questionnaire-based in 1147 late AMD cases and 1773 contr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/413150

    authors: Ersoy L,Ristau T,Lechanteur YT,Hahn M,Hoyng CB,Kirchhof B,den Hollander AI,Fauser S

    更新日期:2014-01-01 00:00:00

  • Isoform-specific Na,K-ATPase alterations precede disuse-induced atrophy of rat soleus muscle.

    abstract::This study examines the isoform-specific effects of short-term hindlimb suspension (HS) on the Na,K-ATPase in rat soleus muscle. Rats were exposed to 24-72 h of HS and we analyzed the consequences on soleus muscle mass and contractile parameters; excitability and the resting membrane potential (RMP) of muscle fibers; ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/720172

    authors: Kravtsova VV,Matchkov VV,Bouzinova EV,Vasiliev AN,Razgovorova IA,Heiny JA,Krivoi II

    更新日期:2015-01-01 00:00:00

  • Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells.

    abstract::Renal inflammation can result in renal injury. Uric acid (UA) is the final product of purine metabolism in humans and because of the lack of urate oxidase, UA may accumulate in tissues, including kidney, causing inflammation. Galangin was isolated from a traditional Chinese medicine plant and possesses several benefic...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3018357

    authors: Lu H,Yao H,Zou R,Chen X,Xu H

    更新日期:2019-05-26 00:00:00

  • Positive Association between ANKRD55 Polymorphism 7731626 and Dermatomyositis/Polymyositis with Interstitial Lung Disease in Chinese Han Population.

    abstract::Single nucleotide polymorphisms (SNPs) in TNFSF4 and ANKRD55 genes have been shown to be associated with several autoimmune diseases, although whether these genes are susceptibility genes for dermatomyositis/polymyositis (DM/PM) has, to date, not been reported. This study aimed to investigate the potential association...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2905987

    authors: Li L,Chen S,Wen X,Wang Q,Lv G,Li J,Yang F,Zhang F,Li Y

    更新日期:2017-01-01 00:00:00

  • Automated Ventricular System Segmentation in Paediatric Patients Treated for Hydrocephalus Using Deep Learning Methods.

    abstract::Hydrocephalus is a common neurological condition that can have traumatic ramifications and can be lethal without treatment. Nowadays, during therapy radiologists have to spend a vast amount of time assessing the volume of cerebrospinal fluid (CSF) by manual segmentation on Computed Tomography (CT) images. Further, som...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3059170

    authors: Klimont M,Flieger M,Rzeszutek J,Stachera J,Zakrzewska A,Jończyk-Potoczna K

    更新日期:2019-07-07 00:00:00

  • Changes in Liver Gene Expression and Plasma Concentration of Rbp4, Fetuin-A, and Fgf21 in Sprague-Dawley Rats Subjected to Different Dietary Interventions and Bariatric Surgery.

    abstract:Purpose:To study the effect of duodenal-jejunal omega switch (DJOS) in combination with different dietary patterns on the retinol-binding protein (RBP4), fetuin-A, and fibroblast growth factor 21 (FGF21) plasma levels and their hepatic gene expressions in rats. Methods:A high-fat diet (HF) was given to 28 rats and 28 ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/3472190

    authors: Stygar D,Pigłowski W,Chełmecka E,Skrzep-Poloczek B,Sawczyn T,Garłowski W,Jochem J,Karcz KW

    更新日期:2018-08-16 00:00:00

  • A Computer-Aided Analysis Method of SPECT Brain Images for Quantitative Treatment Monitoring: Performance Evaluations and Clinical Applications.

    abstract::The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introduced to extract a change-rate map (CRM) as a parametric image for quantifying the...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/1962181

    authors: Zheng X,Wei W,Huang Q,Song S,Wan J,Huang G

    更新日期:2017-01-01 00:00:00

  • Correlation between Pathological Characteristics and Young's Modulus Value of Spastic Gastrocnemius in a Spinal Cord Injury Rat Model.

    abstract::The goal of the present study were (1) to investigate the pathological characteristics of gastrocnemius muscle (GM) and quantitatively assess GM tissue stiffness in rat models with spinal cord injury (SCI) and (2) to explore the correlation between pathological characteristics changes and Young's modulus value of GM. ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/5387948

    authors: Jiang L,Wang YJ,Wang QY,Wang Q,Wei XM,Li N,Guo WP,Dou ZL

    更新日期:2017-01-01 00:00:00

  • How to Choose In Vitro Systems to Predict In Vivo Drug Clearance: A System Pharmacology Perspective.

    abstract::The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry criteria of probe dr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/857327

    authors: Wang L,Chiang C,Liang H,Wu H,Feng W,Quinney SK,Li J,Li L

    更新日期:2015-01-01 00:00:00

  • Onlay Repair Technique for the Management of Ureteral Strictures: A Comprehensive Review.

    abstract::Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, and appendiceal mucosae. Oral mucosa grafts, especially buccal muco...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/6178286

    authors: Xiong S,Wang J,Zhu W,Yang K,Ding G,Li X,Eun DD

    更新日期:2020-07-27 00:00:00

  • The Effect of Butyrate-Supplemented Parenteral Nutrition on Intestinal Defence Mechanisms and the Parenteral Nutrition-Induced Shift in the Gut Microbiota in the Rat Model.

    abstract::Butyrate produced by the intestinal microbiota is essential for proper functioning of the intestinal immune system. Total dependence on parenteral nutrition (PN) is associated with numerous adverse effects, including severe microbial dysbiosis and loss of important butyrate producers. We hypothesised that a lack of bu...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/7084734

    authors: Jirsova Z,Heczkova M,Dankova H,Malinska H,Videnska P,Vespalcova H,Micenkova L,Bartonova L,Sticova E,Lodererova A,Prefertusová L,Sekerkova A,Hradecky J,Cahova M

    更新日期:2019-02-28 00:00:00

  • The Appearance of The Infraorbital Canal and Infraorbital Ethmoid (Haller's) Cells on Panoramic Radiography of Edentulous Patients.

    abstract::Objectives. The aim of the study is to detect the prevalence and the characteristics of infraorbital canal and Haller's cells on panoramic radiography of edentulous patients. Methods. The study group comprised 291 panoramic radiographs of edentulous patients. Radiographs were interpreted for the visibility and charact...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/1293124

    authors: Yesilova E,Bayrakdar IS

    更新日期:2018-07-08 00:00:00

  • A game system for cognitive rehabilitation.

    abstract::Brain injury such as traumatic brain injury (TBI) and stroke is the major cause of long-term disabilities in many countries. The increasing rate of brain damaged victims and the heterogeneity of impairments decrease rehabilitation effectiveness and competence resulting in higher cost of rehabilitation treatment. On th...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/493562

    authors: Shapi'i A,Mat Zin NA,Elaklouk AM

    更新日期:2015-01-01 00:00:00

  • Neutrophil-to-Lymphocyte Ratio Predicts Prognosis in Castration-Resistant Prostate Cancer Patients Who Received Cabazitaxel Chemotherapy.

    abstract:INTRODUCTION AND OBJECTIVES:An elevated neutrophil-to-lymphocyte ratio (NLR) has been suggested to be associated with a poor prognosis in several cancers. We evaluated the utility of an elevated NLR as a biomarker to predict the prognosis of metastatic castration-resistant prostate cancer (mCRPC) patients treated with ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/7538647

    authors: Uemura K,Kawahara T,Yamashita D,Jikuya R,Abe K,Tatenuma T,Yokomizo Y,Izumi K,Teranishi JI,Makiyama K,Yumura Y,Kishida T,Udagawa K,Kobayashi K,Miyoshi Y,Yao M,Uemura H

    更新日期:2017-01-01 00:00:00

  • Autologous bone marrow mesenchymal stem cells associated with tantalum rod implantation and vascularized iliac grafting for the treatment of end-stage osteonecrosis of the femoral head.

    abstract::Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA). However, there have been unsatisfactory success rates for end-stage ONFH. The auth...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2015/240506

    authors: Zhao D,Liu B,Wang B,Yang L,Xie H,Huang S,Zhang Y,Wei X

    更新日期:2015-01-01 00:00:00

  • Based on Network Pharmacology to Explore the Molecular Targets and Mechanisms of Gegen Qinlian Decoction for the Treatment of Ulcerative Colitis.

    abstract:Background:Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for the treatment of ulcerative colitis (UC). In this study, we aimed to identify its molecular target and the mechanism involved in UC treatment by network pharmacology and molecular docking. Material and Methods. The active ingredients of P...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/5217405

    authors: Wei M,Li H,Li Q,Qiao Y,Ma Q,Xie R,Wang R,Liu Y,Wei C,Li B,Zheng C,Sun B,Yu B

    更新日期:2020-11-24 00:00:00

  • The Yemeni Brown Algae Dictyota dichotoma Exhibit High In Vitro Anticancer Activity Independent of Its Antioxidant Capability.

    abstract::The aim of this study was to investigate the anticancer and antioxidant activities as well as the safety of the brown algae Dictyota dichotoma of the Western seacoast of Yemen. Cytotoxicity of methanol extract of D. dichotoma and several of its fractions, petroleum ether, chloroform, ethyl acetate, n-butanol, and aque...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2425693

    authors: El-Shaibany A,Al-Habori M,Al-Maqtari T,Al-Mahbashi H

    更新日期:2020-02-17 00:00:00

  • Phytoremediation potential of Maná-Cubiu (Solanum sessiliflorum Dunal) for the deleterious effects of methylmercury on the reproductive system of rats.

    abstract::Methylmercury, organic form of mercury, can increase the number of abnormal sperm and decrease sperm concentration and testosterone levels possibly due to the damage caused by reactive species to germ and Leydig cells. Maná-cubiu (Solanum sessiliflorum Dunal) is a native fruit from Amazon rich in iron, zinc, niacin, p...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/309631

    authors: Frenedoso da Silva R,Missassi G,dos Santos Borges C,Silva de Paula E,Hornos Carneiro MF,Grotto D,Barbosa Junior F,De Grava Kempinas W

    更新日期:2014-01-01 00:00:00

  • Full-Length cDNA, Prokaryotic Expression, and Antimicrobial Activity of UuHb-F-I from Urechis unicinctus.

    abstract::Hemoglobin, which widely exists in all vertebrates and in some invertebrates, is possibly a precursor of antimicrobial peptides (AMPs). However, AMPs in the hemoglobin of invertebrates have been rarely investigated. This study is the first to report the full-length cDNA, prokaryotic expression, and antimicrobial activ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/5683026

    authors: Niu R,Chen X

    更新日期:2016-01-01 00:00:00

  • Balance dysfunction in Parkinson's disease.

    abstract::Stability and mobility in functional motor activities depend on a precise regulation of phasic and tonic muscular activity that is carried out automatically, without conscious awareness. The sensorimotor control of posture involves a complex integration of multisensory inputs that results in a final motor adjustment p...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/434683

    authors: Rinalduzzi S,Trompetto C,Marinelli L,Alibardi A,Missori P,Fattapposta F,Pierelli F,Currà A

    更新日期:2015-01-01 00:00:00

  • Gastrointestinal Motility, Mucosal Mast Cell, and Intestinal Histology in Rats: Effect of Prednisone.

    abstract::Our aim was to verify the effects of prednisone related to gastrointestinal motility, intestinal histology, and mucosal mast cells in rats. Two-month-old male Wistar rats were randomly assigned to control group (vehicle) animals receiving saline 0.9% (n = 7) or treated orally with 0.625 mg/kg/day of prednisone (n = 7)...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/4637621

    authors: de Lima MB,Gama LA,Hauschildt AT,Dall'Agnol DJR,Corá LA,Americo MF

    更新日期:2017-01-01 00:00:00

  • Optimized Cylindrical Diffuser Powers for Interstitial PDT Breast Cancer Treatment Planning: A Simulation Study.

    abstract:Purpose:It is well known that interstitial photodynamic therapy (iPDT) of large tumors requires effective planning to ensure efficient delivery of therapeutic dose to the target tumors. This should be achieved in parallel with minimal damage to the nearby intact tissues. To that end, clinical iPDT can be attained using...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2061509

    authors: Ismael FS,Amasha H,Bachir W

    更新日期:2020-03-23 00:00:00

  • Steroid Tumor Environment in Male and Female Mice Model of Canine and Human Inflammatory Breast Cancer.

    abstract::Canine inflammatory mammary cancer (IMC) shares clinical and histopathological characteristics with human inflammatory breast cancer (IBC) and has been proposed as a good model for studying the human disease. The aim of this study was to evaluate the capacity of female and male mice to reproduce IMC and IBC tumors and...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8909878

    authors: Caceres S,Peña L,Silvan G,Illera MJ,Woodward WA,Reuben JM,Illera JC

    更新日期:2016-01-01 00:00:00

  • Tanshinone IIA Attenuates Renal Fibrosis after Acute Kidney Injury in a Mouse Model through Inhibition of Fibrocytes Recruitment.

    abstract::Acute kidney injury (AKI) is associated with an increased risk of developing advanced chronic kidney disease (CKD). Yet, effective interventions to prevent this conversion are unavailable for clinical practice. In this study, we examined the beneficial effects of Tanshinone IIA on renal fibrosis in a mouse model of fo...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/867140

    authors: Jiang C,Shao Q,Jin B,Gong R,Zhang M,Xu B

    更新日期:2015-01-01 00:00:00