Abstract:
:Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA). However, there have been unsatisfactory success rates for end-stage ONFH. The authors describe a modified technique using bone marrow mesenchymal stem cells (BMMSCs) associated with porous tantalum rod implantation combined with vascularized iliac grafting for the treatment of end-stage ONFH. A total of 24 patients (31 hips) with end-stage ONFH were treated with surgery; ARCO IIIc stage was observed in 19 hips and ARCO IV stage was observed in 12 hips. All patients were followed for a mean time of 64.35 ± 13.03 months (range 26-78). Operations on only five hips were converted to THA. The joint-preserving success rate of the entire group was 89.47% for ARCO stage IIIc and 75% for ARCO stage IV. The mean Harris hip score of the 31 hips improved significantly from 38.74 ± 5.88 points (range 22-50) to 77.23 ± 14.75 points (range 33-95). This intervention was safe and effective in delaying or avoiding total hip replacement for end-stage ONFH.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Zhao D,Liu B,Wang B,Yang L,Xie H,Huang S,Zhang Y,Wei Xdoi
10.1155/2015/240506subject
Has Abstractpub_date
2015-01-01 00:00:00pages
240506eissn
2314-6133issn
2314-6141journal_volume
2015pub_type
杂志文章,随机对照试验abstract::Introduction. Infection and apoptosis are combined triggers for inflammation in dental tissues. Octamer-binding transcription factor 4-B1 (OCT4B1), a novel spliced variant of OCT4 family, could respond to the cellular stress and possess antiapoptotic property. However, its specific role in dental pulpitis remains unkn...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2756891
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/4616417
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journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2013/424280
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/380531
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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abstract::Functional connectivity has been correlated with a patient's level of consciousness and has been found to be altered in several neuropsychiatric disorders. Absence epilepsy patients, who experience a loss of consciousness, are assumed to suffer from alterations in thalamocortical networks; however, previous studies ha...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2013/734893
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5603958
更新日期:2020-08-12 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5201014
更新日期:2019-02-10 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/814543
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3951783
更新日期:2018-11-25 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/4193541
更新日期:2020-11-17 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/318364
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/3521859
更新日期:2020-06-11 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/626452
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:The aim of our work was to investigate the causal connection between M1 and M2 macrophage phenotypes occurrence and prostate cancer, their correlation with tumor extension (ECE), and biochemical recurrence (BR). PATIENT AND METHODS:Clinical and pathological data were prospectively gathered from 93 patient...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/486798
更新日期:2014-01-01 00:00:00
abstract::High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/512027
更新日期:2015-01-01 00:00:00
abstract::Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2935195
更新日期:2017-01-01 00:00:00
abstract::IL-1 family includes IL-38 (IL-1F10) and the subfamily of IL-36 and is the central mediators of inflammatory diseases, including pustular psoriasis, atopic dermatitis, rheumatoid arthritis, and gut inflammation. The purpose of the study was to evaluate on tissue of the patients with inflammatory bowel disease (IBD), t...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/5140691
更新日期:2018-12-10 00:00:00
abstract::Activity-dependent plasticity as a result of reorganization of neural circuits is a fundamental characteristic of the central nervous system that occurs simultaneously in multiple sites. In this study, we established the effects of subthreshold transcranial magnetic stimulation (TMS) over the primary motor cortex regi...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2013/516427
更新日期:2013-01-01 00:00:00
abstract::Bacteria are a source of a large number of secondary metabolites with several biomedical and biotechnological applications. In recent years, there has been tremendous progress in the development of novel synthetic biology approaches both to increase the production rate of secondary metabolites of interest in native pr...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/7021826
更新日期:2018-07-09 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/241780
更新日期:2013-01-01 00:00:00
abstract::Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on lipid and glucose homeostasis. Previous study demonstrated that FGF21 might be one of the Sp1 target genes. However, the transcriptional role of Sp1 on FGF21 in adipose tissue and liver has not been reported. In this study, ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/8402035
更新日期:2017-01-01 00:00:00
abstract::Detection of single based genetic mutation by using oligonucleotide probes is one of the common methods of detecting single nucleotide polymorphisms at known loci. In this paper, we demonstrated a hybridization system which included a buffer solution that produced selective salt-induced effect and a locked nucleic aci...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/391070
更新日期:2015-01-01 00:00:00
abstract::The regiospecific distribution of fatty acids (FAs) and composition of triglyceride (TAG) molecular species of fishes were analyzed and calculated by pancreatic lipase (PL) hydrolysis and Visual Basic (VB) program. DHA was preferentially located at sn-2 position in TAG molecule, whereas EPA was almost equally distribu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9016840
更新日期:2018-01-29 00:00:00
abstract:Background:Fibroid is the most common benign tumor of the uterus and if associated with pregnancy may adversely affect the outcome of pregnancy. Objective of the present study was to assess the obstetric outcome (maternal and fetal) in pregnancy with fibroid. Methods:A prospective observational study was performed ove...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8367068
更新日期:2018-03-26 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,多中心研究
doi:10.1155/2019/7041607
更新日期:2019-06-19 00:00:00
abstract:BACKGROUND:Delayed union and nonunion are common complications in atypical femoral fractures (AFFs) despite having good fracture fixation. Demineralized bone matrix (DBM) is a successfully proven method for enhancing fracture healing of the long bone fracture and nonunion and should be used in AFFs. This study aimed to...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2016/4061539
更新日期:2016-01-01 00:00:00
abstract::Angiogenesis is essential for tumor growth and metastasis. Over the last decades, a substantial progress has been achieved in defining different patterns of tumor microcirculation. Sprouting angiogenesis, the oldest model of microcirculation, is the de novo vessel formation from preexisting blood vessels. Vessel split...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/986768
更新日期:2014-01-01 00:00:00
abstract::Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) indu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9436280
更新日期:2017-01-01 00:00:00
abstract:Background:Many studies, comparing the health associated risks of electronic cigarettes with conventional cigarettes focus mainly on the common chemical compounds found between them. Aim:Review chemical compounds found exclusively in electronic cigarettes and describe their toxic effects, focusing on electronic-cigare...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/1386710
更新日期:2019-12-19 00:00:00