From sprouting angiogenesis to erythrocytes generation by cancer stem cells: evolving concepts in tumor microcirculation.

abstract：:Objectives. To investigate the protective effects of tropisetron on acetaminophen- (APAP-) induced liver injury in a mice model. Methods. C57BL/6 male mice were given tropisetron (0.3 to 10 mg/kg) 30 minutes before a hepatotoxic dose of acetaminophen (300 mg/kg) intraperitoneally. Twenty hours after APAP intoxication,...

journal_title：BioMed research international

authors： Liu FC,Lee HC,Liao CC,Li AH,Yu HP

更新日期：2016-01-01 00:00:00

abstract：:We evaluated the effects of mechanical stimulation on the osteogenic differentiation of human intraoral mesenchymal stem and progenitor cells (MSPCs) using the Flexcell FX5K Tension System that mediated cyclic tensile stretch on the cells. MSPCs were isolated from human mandibular retromolar bones and characterized us...

journal_title：BioMed research international

authors： Lohberger B,Kaltenegger H,Stuendl N,Payer M,Rinner B,Leithner A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Novel prognostic markers are needed so newly diagnosed breast cancer patients do not undergo any unnecessary therapy. Various microarray gene expression datasets based studies have generated gene signatures to predict the prognosis outcomes, while ignoring the large amount of information contained in establi...

journal_title：BioMed research international

authors： Saini A,Hou J,Zhou W

更新日期：2014-01-01 00:00:00

abstract：:This paper presents a rapid label-free method for the identification of morphological characteristics of biological cells. Based on quantitative phase microscopy as well as the connotation of phase value, the gradient operator of phase and the associated analytic processing are employed to determine the edge of differ...

journal_title：BioMed research international

authors： Tang WB,Ji Y,Zhang MM,Chen ZY,Xu YY,Wang YW

更新日期：2018-04-11 00:00:00

abstract：INTRODUCTION:Spectroscopic analysis of urine samples from laboratory animals can be used to predict the efficacy and side effects of drugs. This employs methods combining (1)H NMR spectroscopy with quantification of biomarkers or with multivariate data analysis. The most critical steps in data evaluation are analytical...

journal_title：BioMed research international

authors： Schreier C,Kremer W,Huber F,Neumann S,Pagel P,Lienemann K,Pestel S

更新日期：2013-01-01 00:00:00

abstract：:Historically, the colistin has been thought to kill bacteria through membrane lysis. Here, we present an alternative mechanism that colistin induces rapid Paenibacillus polymyxa death through reactive oxygen species production. This significantly augments our understanding of the mechanism of colistin action, which is...

journal_title：BioMed research international

authors： Yu Z,Zhu Y,Qin W,Yin J,Qiu J

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To compare the quantity, subtype, and progression of atherosclerosis by cardiac computed tomography (CT) and intravascular ultrasound (IVUS) in patients with stable (SAP) and unstable angina pectoris or non-ST-elevation myocardial infarction (UAP/n-STEMI). METHODS:Forty patients with SAP and 20 with UAP/n-ST...

journal_title：BioMed research international

authors： Dalager MG,Bøttcher M,Thygesen J,Andersen G,Bøtker HE

更新日期：2015-01-01 00:00:00

abstract：:Internally symmetric proteins are proteins that have a symmetrical structure in their monomeric single-chain form. Around 10-15% of the protein domains can be regarded as having some sort of internal symmetry. In this regard, we previously published SymD (symmetry detection), an algorithm that determines whether a giv...

journal_title：BioMed research international

authors： Jha A,Flurchick KM,Bikdash M,Kc DB

更新日期：2016-01-01 00:00:00

abstract：:Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and exist as an important cause of pulmonary infections in humans. Pulmonary involvement is the most common disease manifestation of NTM and the incidence of NTM is growing in North America. Susceptibility to NTM infection is incompletely understood; ...

journal_title：BioMed research international

authors： Mirsaeidi M,Farshidpour M,Allen MB,Ebrahimi G,Falkinham JO

更新日期：2014-01-01 00:00:00

abstract：:Endometriosis is a chronic disease of women in the reproductive age, defined as endometrial cells growing outside of the uterine cavity and associated with relapses. Relapses are hypothesized to correlate with incomplete surgical excision or result from nonrandom implantation of new endometrial implants in adjacent pe...

journal_title：BioMed research international

authors： Renner SP,Strissel PL,Beckmann MW,Lermann J,Burghaus S,Hackl J,Fasching PA,Strick R

更新日期：2015-01-01 00:00:00

abstract：:To explore the antitumor effect of hypoxia-inducible factor-1α short hairpin RNA (HIF-1α shRNA) delivered by ultrasound targeted microbubble destruction (UTMD) and transcatheter arterial embolization (TAE) on rats with hepatic cancer. After the models of transplantation hepatoma were established, Wistar rats were rand...

journal_title：BioMed research international

authors： Liao Y,Luo H,He Z,Kuang Y,Chen P,Zhang X,Chen J,Wen Q,Xie Y,Ding S

更新日期：2019-02-19 00:00:00

abstract：:Both thyroid hormones and irisin have profound influences on the metabolism of the human body. Based on their similarities, several studies have been conducted to explore changes in irisin levels in patients with hypothyroidism and hyperthyroidism. This study was conducted in accordance with the PRISMA statement and t...

journal_title：BioMed research international

authors： Shan D,Zou L,Liu X,Cai Y,Dong R,Hu Y

更新日期：2020-10-28 00:00:00

abstract：:Aging is the principal risk factor for the development of Alzheimer's disease (AD). The hallmarks of AD are accumulation of the amyloid-β peptide 1-42 (Aβ42) and abnormal hyperphosphorylation of Tau (p-Tau) protein in different areas of the brain and, more recently reported, in the visual cortex. Recently, Aβ42 peptid...

journal_title：BioMed research international

authors： Hernández-Zimbrón LF,Perez-Hernández M,Torres-Romero A,Gorostieta-Salas E,Gonzalez-Salinas R,Gulias-Cañizo R,Quiroz-Mercado H,Zenteno E

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Severe sepsis and septic shock are the primary causes of multiple organ dysfunction syndrome (MODS), which is the most frequent cause of death in intensive care unit patients. Many pro- and anti-inflammatory mediators, such as interleukin-6 (IL-6), play a strategic role in septic syndrome. Continuous renal...

journal_title：BioMed research international

authors： Servillo G,Vargas M,Pastore A,Procino A,Iannuzzi M,Capuano A,Memoli A,Riccio E,Memoli B

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study is to investigate the stress distributions of different restoration options for class II mesio-occluso-distal (MOD) cavities. A class II MOD cavity with proximal box gingival floor 1 mm below cementoenamel junction was designed in a mandibular first molar tooth model. 3D finite-element analysis (...

journal_title：BioMed research international

authors： Alp Ş,Gulec Alagoz L,Ulusoy N

更新日期：2020-12-15 00:00:00

abstract：:J-proteins are molecular chaperones and present in a wide variety of organisms from prokaryote to eukaryote. Based on their domain organizations, J-proteins can be classified into 4 types, that is, Type I, Type II, Type III, and Type IV. Different types of J-proteins play distinct roles in influencing cancer propertie...

journal_title：BioMed research international

authors： Feng P,Lin H,Chen W,Zuo Y

更新日期：2014-01-01 00:00:00

abstract：Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

journal_title：BioMed research international

authors： Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

更新日期：2020-12-19 00:00:00

abstract：:Germacrone, a natural 10-membered monocyclic sesquiterpene with three double bonds and a ketone, was isolated from the roots of traditional Chinese medicine Saussurea costus (SC). The pharmacological value and intrinsic mechanism of germacrone in the treatment of esophageal squamous cell carcinoma (ESCC) are still unc...

journal_title：BioMed research international

authors： Zhang R,Hao J,Guo K,Liu W,Yao F,Wu Q,Liu C,Wang Q,Yang X

更新日期：2020-01-30 00:00:00

abstract：Objectives:Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han...

journal_title：BioMed research international

authors： Yang S,Li K,Zhu MM,Yuan XD,Jiao XL,Yang YY,Li J,Li L,Zhang HN,Du YH,Wei YX,Qin YW

更新日期：2019-10-13 00:00:00

abstract：:Spinocerebellar ataxia-3 (SCA3) is the most common dominant inherited ataxia worldwide and is caused by an unstable CAG trinucleotide expansion mutation within the ATXN3 gene, resulting in an expanded polyglutamine tract within the ATXN3 protein. Many in vitro studies have examined the role of autophagy in neurodegene...

journal_title：BioMed research international

authors： Ou Z,Luo M,Niu X,Chen Y,Xie Y,He W,Song B,Xian Y,Fan D,OuYang S,Sun X

更新日期：2016-01-01 00:00:00

abstract：:Synovitis plays an important role in the pathogenesis of arthritis, which is closely related to the joint swell and pain of patients. The purpose of this study was to investigate the anti-inflammatory effects of pulsed electromagnetic fields (PEMF) on synovitis and its underlying mechanisms. Destabilization of the med...

journal_title：BioMed research international

authors： Ouyang J,Zhang B,Kuang L,Yang P,Du X,Qi H,Su N,Jin M,Yang J,Xie Y,Tan Q,Chen H,Chen S,Jiang W,Liu M,Luo X,He M,Ni Z,Chen L

更新日期：2020-05-26 00:00:00

abstract：:Three novel low molecular weight polysaccharides (RLP-1a, RLP-2a, and RLP-3a) with 9004, 8761, and 7571 Da were first obtained by purifying the crude polysaccharides from the fruits of a traditional Chinese medicinal herb Rosae Laevigatae. The conditions for polysaccharides from the R. Laevigatae fruit (RLP) extractio...

journal_title：BioMed research international

authors： Zhang X,Hu Y,Jin C,Wu W

更新日期：2020-10-22 00:00:00

abstract：:Based on low carbon wastewater as the research object and using corncob as an external solid carbon source, the performance of corncob organic matter was assessed for its release potential, quantity of release, and safety of use. The effects of varying quantities of the solid carbon source on simultaneous nitrificatio...

journal_title：BioMed research international

authors： Zhang LQ,He PF,Wu D,Li SG,Huang YL,Huang YW,Wang DM

更新日期：2017-01-01 00:00:00

abstract：Background:Studies of previous cohorts have demonstrated a controversial association between extreme body mass index (BMI) and complication rates following total hip arthroplasty (THA). The purpose of this study was to compare 30-day perioperative complications in underweight (BMI <18.50 kg/m2), normal-weight (BMI 18.5...

journal_title：BioMed research international

authors： Hung CY,Chang CH,Lin YC,Lee SH,Chen SY,Hsieh PH

更新日期：2019-10-07 00:00:00

abstract：:The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia f...

journal_title：BioMed research international

authors： Haufe T,Förch S,Müller P,Plath J,Mayr E

更新日期：2016-01-01 00:00:00

abstract：:Catalases are widely used in many scientific areas. A catalase gene (Kat) from Geobacillus sp. CHB1 encoding a monofunctional catalase was cloned and recombinant expressed in Escherichia coli (E. coli), which was the first time to clone and express this type of catalase of genus Geobacillus strains as far as we know. ...

journal_title：BioMed research international

authors： Jia X,Chen J,Lin C,Lin X

更新日期：2016-01-01 00:00:00

abstract：:Background. Findings on the association between posttransplant anemia (PTA) and mortality in posttransplant patients are scarce. This study explored whether PTA shortly after kidney transplantation (KT) predicts mortality at up to 10 years' follow-up, stratified for chronic kidney disease (CKD) stages. Methods. PTA wa...

journal_title：BioMed research international

authors： Majernikova M,Rosenberger J,Prihodova L,Jarcuskova M,Roland R,Groothoff JW,van Dijk JP

更新日期：2017-01-01 00:00:00

abstract：:New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full-fledged annotation systems are usually home-grown and customized to a particular geno...

journal_title：BioMed research international

authors： Alioto T,Picardi E,Guigó R,Pesole G

更新日期：2013-01-01 00:00:00

abstract：Background:With the continuous improvement of the modernization of the Chinese military and the major adjustments made by the state to the recruitment policy, the newly recruited military undergone multiple pressures such as targeted high-intensity military training and environmental changes. The mental health of milit...

journal_title：BioMed research international

authors： Tao N,An H,Zhang J,Zhang Y,Jin L,Xu L,Liu J,Xu X

更新日期：2020-04-02 00:00:00

abstract：:Anopheles gambiae is the major malaria vector in Africa. Examining the molecular basis of A. gambiae traits requires knowledge of both genetic variation and genome-wide linkage disequilibrium (LD) map of wild A. gambiae populations from malaria-endemic areas. We sequenced the genomes of nine wild A. gambiae mosquitoes...

journal_title：BioMed research international

authors： Wang X,Afrane YA,Yan G,Li J

更新日期：2015-01-01 00:00:00