The Role of a Primary Arthroplasty in the Treatment of Proximal Tibia Fractures in Orthogeriatric Patients.

Abstract:

:The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia fracture in our institution between 01/2008 and 12/2014. We collected the following statistical data from each patient: age, classification of the fracture (AO-classification), type of prosthesis used, length of the operation and hospitalization, and complications during the follow-up. We used the Knee Society Score (KSS) and the WOMAC score to evaluate the function. The Knee Society Score showed an average "general knee score" (KSS1) of 81.1 points and an average "functional knee score" (KSS2) of 74.5 points. The average WOMAC score was 78.6 points. Immediate postoperative mobilization with the possibility of a full-weight bearing is of crucial importance for the geriatric patients to maintain the mobility they had prior to the operation and reduce medical complications. Because of these advantages, the primary TKA seems to be a promising alternative to the ORIF of a proximal tibia fracture in the orthogeriatric patient.

journal_name

Biomed Res Int

authors

Haufe T,Förch S,Müller P,Plath J,Mayr E

doi

10.1155/2016/6047876

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

6047876

eissn

2314-6133

issn

2314-6141

journal_volume

2016

pub_type

杂志文章
  • Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes.

    abstract::Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite effect under other...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/201475

    authors: Advani A,Connelly KA,Advani SL,Thai K,Zhang Y,Kelly DJ,Gilbert RE

    更新日期:2013-01-01 00:00:00

  • Incidence and Predictors of Catheterization-Related Cerebral Infarction on Diffusion-Weighted Magnetic Resonance Imaging.

    abstract::Introduction. The aim of this study was to examine the incidence and risk factors of catheterization-related CI in the contemporary era, using diffusion-weighted magnetic resonance imaging. Methods. We retrospectively analyzed consecutive 84 patients who underwent MRI (magnetic resonance imaging) after 2.81 ± 2.4 days...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/6052125

    authors: Morita Y,Kato T,Okano M,Suu K,Kimura M,Minamino-Muta E,Nakane E,Izumi T,Miyamoto S,Haruna T,Ueyama K,Inoko M

    更新日期:2016-01-01 00:00:00

  • The Effect of Stroke Subtypes on Baroreceptor Sensitivity, a Predict for Acute Stroke Outcome.

    abstract:Background:Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS varies in different subtypes of acute ischemic stroke (AIS) and that BRS is a predictor of clinical outcomes. Methods:We examined autonomic parameters in 34 patients with AI...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/7614828

    authors: Tsai WC,Lin HC,Lai YR,Hsu CW,Huang CC,Wang HC,Su CM,Su YJ,Lin WC,Cheng BC,Chang WN,Lu CH,Tsai NW

    更新日期:2019-04-18 00:00:00

  • ASPic-GeneID: a lightweight pipeline for gene prediction and alternative isoforms detection.

    abstract::New genomes are being sequenced at an increasingly rapid rate, far outpacing the rate at which manual gene annotation can be performed. Automated genome annotation is thus necessitated by this growth in genome projects; however, full-fledged annotation systems are usually home-grown and customized to a particular geno...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/502827

    authors: Alioto T,Picardi E,Guigó R,Pesole G

    更新日期:2013-01-01 00:00:00

  • XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer.

    abstract::X-ray radiation resistance associated 1 (XRRA1) has been found to regulate the response of human tumor and normal cells to X-radiation (XR). Although XRRA1 overexpression is known to be involved in cancer cell response to XR, there are no reports about whether the expression of XRRA1 in tumors can adjust radioresistan...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/5718968

    authors: Wang W,Guo M,Xia X,Zhang C,Zeng Y,Wu S

    更新日期:2017-01-01 00:00:00

  • Identification of Sp1 as a Transcription Activator to Regulate Fibroblast Growth Factor 21 Gene Expression.

    abstract::Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on lipid and glucose homeostasis. Previous study demonstrated that FGF21 might be one of the Sp1 target genes. However, the transcriptional role of Sp1 on FGF21 in adipose tissue and liver has not been reported. In this study, ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/8402035

    authors: Chen S,Li H,Zhang J,Jiang S,Zhang M,Xu Y,Dong K,Yang Y,Fang Q,Jia W

    更新日期:2017-01-01 00:00:00

  • Seasonal Variation in Essential Oils Composition and the Biological and Pharmaceutical Protective Effects of Mentha longifolia Leaves Grown in Tunisia.

    abstract::This research assessed the seasonal variation of the chemical composition and antibacterial and anticholinesterase activities of essential oils extracted from M. longifolia leaves. The leaves organic fractions were also investigated for their biological activities and pharmacological functions. The essential oil highe...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/7856517

    authors: Zouari-Bouassida K,Trigui M,Makni S,Jlaiel L,Tounsi S

    更新日期:2018-12-09 00:00:00

  • RIRS with Vacuum-Assisted Ureteral Access Sheath versus MPCNL for the Treatment of 2-4 cm Renal Stone.

    abstract:Objective:Comparison of outcomes between RIRS with vacuum-assisted ureteral access sheath (V-UAS) and MPCNL in the treatment of renal stone. Materials and Methods:28 patients with 2-4 cm renal stone were treated using RIRS with 14/16 F V-UAS. The outcomes were compared to those who underwent MPCNL with 16 F Amplatz sh...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/8052013

    authors: Lai D,He Y,Li X,Chen M,Zeng X

    更新日期:2020-05-14 00:00:00

  • New developments in peritoneal fibroblast biology: implications for inflammation and fibrosis in peritoneal dialysis.

    abstract::Uraemia and long-term peritoneal dialysis (PD) can lead to fibrotic thickening of the peritoneal membrane, which may limit its dialytic function. Peritoneal fibrosis is associated with the appearance of myofibroblasts and expansion of extracellular matrix. The extent of contribution of resident peritoneal fibroblasts ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/134708

    authors: Witowski J,Kawka E,Rudolf A,Jörres A

    更新日期:2015-01-01 00:00:00

  • Evaluation of Lateral-Flow Assay for Rapid Detection of Influenza Virus.

    abstract:Background:Influenza virus mainly causes acute respiratory infections in humans. However, the diagnosis of influenza is not accurate based on clinical evidence, as the symptoms of flu are similar to other respiratory virus. The lateral-flow assay is a rapid method to detect influenza virus. But the effectiveness of the...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/3969868

    authors: Han MY,Xie TA,Li JX,Chen HJ,Yang XH,Guo XG

    更新日期:2020-09-08 00:00:00

  • Responders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis.

    abstract:PURPOSE:To evaluate the similarities and differences between the variety of platelet-rich plasma (PRP) formulations, preparation, and uses to try to determine the best responses for the treatment of knee osteoarthritis. MATERIALS AND METHODS:A comparison of the outcomes of randomized controlled trials (RCTs) included ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/7538604

    authors: Milants C,Bruyère O,Kaux JF

    更新日期:2017-01-01 00:00:00

  • Stem cell therapy for lower extremity diabetic ulcers: where do we stand?

    abstract::The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/462179

    authors: Yang M,Sheng L,Zhang TR,Li Q

    更新日期:2013-01-01 00:00:00

  • Mitochondria Associated MicroRNA Expression Profiling of Heart Failure.

    abstract::Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a pressure overload-induced early and late stage heart fai...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/4042509

    authors: Wang X,Song C,Zhou X,Han X,Li J,Wang Z,Shang H,Liu Y,Cao H

    更新日期:2017-01-01 00:00:00

  • Impact of Moderate Heat, Carvacrol, and Thymol Treatments on the Viability, Injury, and Stress Response of Listeria monocytogenes.

    abstract::The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/548930

    authors: Guevara L,Antolinos V,Palop A,Periago PM

    更新日期:2015-01-01 00:00:00

  • Transfected early growth response gene-1 DNA enzyme prevents stenosis and occlusion of autogenous vein graft in vivo.

    abstract::The aim of this study was to detect the inhibitory action of the early growth response gene-1 DNA enzyme (EDRz) as a carrying agent by liposomes on vascular smooth muscle cell proliferation and intimal hyperplasia. An autogenous vein graft model was established. EDRz was transfected to the graft vein. The vein graft s...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/310406

    authors: Liu C,Zhang X,Wang S,Cheng M,Liu C,Wang S,Hu X,Zhang Q

    更新日期:2013-01-01 00:00:00

  • Cloning and expression of synthetic genes encoding the broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris.

    abstract::We have evaluated the cloning and functional expression of previously described broad antimicrobial spectrum bacteriocins SRCAM 602, OR-7, E-760, and L-1077, by recombinant Pichia pastoris. Synthetic genes, matching the codon usage of P. pastoris, were designed from the known mature amino acid sequence of these bacter...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/767183

    authors: Arbulu S,Jiménez JJ,Gútiez L,Cintas LM,Herranz C,Hernández PE

    更新日期:2015-01-01 00:00:00

  • Lentiviral-mediated silencing of farnesyl pyrophosphate synthase through RNA interference in mice.

    abstract::Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/914026

    authors: Yang J,Zhao CZ,Chen B,Chen F,Han J,Hu SJ

    更新日期:2015-01-01 00:00:00

  • Gene Expression Profile of Colon Mucosa after Cytotoxic Insult in wt and Apc-Mutated Pirc Rats: Possible Relation to Resistance to Apoptosis during Carcinogenesis.

    abstract::Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h af...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/1310342

    authors: Femia AP,Luceri C,Lodovici M,Crucitta S,Caderni G

    更新日期:2016-01-01 00:00:00

  • Recent Advances in HBV Reactivation Research.

    abstract::Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/2931402

    authors: Guo L,Wang D,Ouyang X,Tang N,Chen X,Zhang Y,Zhu H,Li X

    更新日期:2018-12-26 00:00:00

  • Treating Small Bowel Obstruction with a Manual Physical Therapy: A Prospective Efficacy Study.

    abstract::Small bowel obstructions (SBOs) caused by adhesions are a common, often life-threatening postsurgical complication with few treatment options available for patients. This study examines the efficacy of a manual physical therapy treatment regimen on the pain and quality of life of subjects with a history of bowel obstr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/7610387

    authors: Rice AD,Patterson K,Reed ED,Wurn BF,Klingenberg B,King CR 3rd,Wurn LJ

    更新日期:2016-01-01 00:00:00

  • Lung Involvements in Rheumatic Diseases: Update on the Epidemiology, Pathogenesis, Clinical Features, and Treatment.

    abstract::Lung illness encountered in patients with rheumatic diseases bears clinical significance in terms of increased morbidity and mortality as well as potential challenges placed on patient care. Although our understanding of natural history of this important illness is still limited, epidemiologic knowledge has been accum...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2018/6930297

    authors: Ha YJ,Lee YJ,Kang EH

    更新日期:2018-05-08 00:00:00

  • Pulmonary Rehabilitation for Exercise Tolerance and Quality of Life in IPF Patients: A Systematic Review and Meta-Analysis.

    abstract:Objective:The aim of this study is to evaluate the efficacy and safety of pulmonary rehabilitation (PR) in patients with idiopathic pulmonary fibrosis (IPF). Methods. Embase, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chongqing VIP (CQVIP), Wanfang Data, and Chinese Biomedical Literature ...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2019/8498603

    authors: Yu X,Li X,Wang L,Liu R,Xie Y,Li S,Li J

    更新日期:2019-03-21 00:00:00

  • Spider silk as guiding biomaterial for human model neurons.

    abstract::Over the last years, a number of therapeutic strategies have emerged to promote axonal regeneration. An attractive strategy is the implantation of biodegradable and nonimmunogenic artificial scaffolds into injured peripheral nerves. In previous studies, transplantation of decellularized veins filled with spider silk f...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/906819

    authors: Roloff F,Strauß S,Vogt PM,Bicker G,Radtke C

    更新日期:2014-01-01 00:00:00

  • Low-Molecular-Weight Polyethyleneimine Grafted Polythiophene for Efficient siRNA Delivery.

    abstract::Owing to its hydrophilicity, negative charge, small size, and labile degradation by endogenous nucleases, small interfering RNA (siRNA) delivery must be achieved by a carrier system. In this study, cationic copolymers composed of low-molecular-weight polyethylenimine and polythiophenes were synthesized and evaluated a...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/406389

    authors: He P,Hagiwara K,Chong H,Yu HH,Ito Y

    更新日期:2015-01-01 00:00:00

  • MicroRNAs: new regulators of Toll-like receptor signalling pathways.

    abstract::Toll-like receptors (TLRs), a critical family of pattern recognition receptors (PRRs), are responsible for the innate immune responses via signalling pathways to provide effective host defence against pathogen infections. However, TLR-signalling pathways are also likely to stringently regulate tissue maintenance and h...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/945169

    authors: He X,Jing Z,Cheng G

    更新日期:2014-01-01 00:00:00

  • Integrins in trabecular meshwork and optic nerve head: possible association with the pathogenesis of glaucoma.

    abstract::Integrins are a family of membrane-spanning proteins that are important receptors for cell adhesion to extracellular matrix proteins. They also provide connections between the extracellular environment and intracellular cytoskeletons and are responsible for activation of many intracellular signaling pathways. In vitro...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/202905

    authors: Zhong Y,Wang J,Luo X

    更新日期:2013-01-01 00:00:00

  • Neurological Complications after Lateral Transpsoas Approach to Anterior Interbody Fusion with a Novel Flat-Blade Spine-Fixed Retractor.

    abstract::Introduction. The lateral lumbar interbody fusion (LLIF) surgical approach has potential advantages over other approaches but is associated with some unique neurologic risks due to the proximity of the lumbosacral plexus. The present study analyzed complications following LLIF surgical approach using a novel single fl...

    journal_title:BioMed research international

    pub_type: 杂志文章,多中心研究

    doi:10.1155/2016/8450712

    authors: Nunley P,Sandhu F,Frank K,Stone M

    更新日期:2016-01-01 00:00:00

  • Radiopharmaceutical stem cell tracking for neurological diseases.

    abstract::Although neurological ailments continue to be some of the main causes of disease burden in the world, current therapies such as pharmacological agents have limited potential in the restoration of neural functions. Cell therapies, firstly applied to treat different hematological diseases, are now being investigated in ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/417091

    authors: Rosado-de-Castro PH,Pimentel-Coelho PM,Gutfilen B,Lopes de Souza SA,de Freitas GR,Mendez-Otero R,Barbosa da Fonseca LM

    更新日期:2014-01-01 00:00:00

  • Psoriasis and Risk of Uveitis: A Systematic Review and Meta-Analysis.

    abstract:Background:Uveitis is a known ophthalmologic manifestation of seronegative spondyloarthropathy, including psoriatic arthritis. However, the data is less clear among patients with psoriasis due to the limited number of published studies. Aims:To investigate whether the risk of incident and prevalent uveitis is elevated...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/9308341

    authors: Chaiyabutr C,Ungprasert P,Silpa-Archa N,Wongpraparut C,Chularojanamontri L

    更新日期:2020-07-15 00:00:00

  • Bioactive surface modification of hydroxyapatite.

    abstract::The purpose of this study was to establish an acid-etching procedure for altering the Ca/P ratio of the nanostructured surface of hydroxyapatite (HAP) by using surface chemical and morphological analyses (XPS, XRD, SEM, surface roughness, and wettability) and to evaluate the in vitro response of osteoblast-like cells ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/626452

    authors: Abe Y,Okazaki Y,Hiasa K,Yasuda K,Nogami K,Mizumachi W,Hirata I

    更新日期:2013-01-01 00:00:00