Transfected early growth response gene-1 DNA enzyme prevents stenosis and occlusion of autogenous vein graft in vivo.

abstract：Background:Thyroid cancer is the most common endocrine malignancy, with a recent global increase of 20% in age-related incidence. Ultrasonography and ultrasonography-guided fine-needle aspiration biopsy (FNAB) are the most widely used diagnostic tests for thyroid nodules; however, it is estimated that up to 25% of thyr...

journal_title：BioMed research international

authors： Nan BY,Xiong GF,Zhao ZR,Gu X,Huang XS

更新日期：2021-01-12 00:00:00

abstract：:Tripartite Motif Containing 11 (TRIM11), an E3 ubiquitin ligase, is identified as a carcinogen causing certain human cancers. However, the specific role of TRIM11 is still uncovered in human osteosarcoma (OS) cells. To explore the role of TRIM11 in OS cells, TRIM11 was induced by silencing and overexpression in OS cel...

journal_title：BioMed research international

authors： Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

更新日期：2019-12-25 00:00:00

abstract：:Astragalus membranaceus polysaccharide (APS) components are main ingredients of TCM and have proven efficacy to activate T cells and B cells, enhancing immunity in humans. In this study, elevated cytokine and anti-PD-1 antibody titers were found in mice after immunization with APS. Therefore, phage-display technology ...

journal_title：BioMed research international

authors： Chang FL,Tsai KC,Lin TY,Yang TW,Lo YN,Chen WC,Chang JH,Lu MK,Chiou CT,Chen PH,Yen Y,Pan SL,Lee YC

更新日期：2020-03-03 00:00:00

abstract：:Heat shock proteins 70 and heat shock proteins 90 (Hsp70/90) have been implicated in many crucial steps of carcinogenesis: stabilizing oncogenic proteins, inhibiting programmed cell death and replicative senescence, induction of tumor angiogenesis, and activation of the invasion and metastasis. Plenty of cancer relate...

journal_title：BioMed research international

authors： Wang H,Tan MS,Lu RC,Yu JT,Tan L

更新日期：2014-01-01 00:00:00

abstract：:Background. Stenotrophomonas maltophilia bacteremia (SMB) is the most perilous situation as compared to other types of S. maltophilia infection. The present study aimed to investigate the clinical features, distribution, drug resistance, and predictors of survival of SMB in a tertiary-care hospital of China. Methods. ...

journal_title：BioMed research international

authors： Chen Y,Suo J,Du M,Chen L,Liu Y,Wang L,Liang Z

更新日期：2019-12-09 00:00:00

abstract：:There has been a remarkable interest in finding lipid inhibitors from natural products to replace synthetic compounds, and a variety of oriental medicinal herbs are reported to have biological activity with regard to lipid inhibition. Buginawa (Bugi) is a novel combined formula that contains twelve medicinal herbs wit...

journal_title：BioMed research international

authors： Park YJ,Seo DW,Ju JY,Cha YY,An HJ

更新日期：2019-07-30 00:00:00

abstract：:Iran is one of the six countries with the most cutaneous leishmaniasis (CL) patients. Understanding better the genotypes of the parasite population in relation to geography and climate is critical to achieving better CL control. We aimed to characterise the population structure of Leishmania tropica, the cause of anth...

journal_title：BioMed research international

authors： Ghatee MA,Mirhendi H,Marashifard M,Kanannejad Z,Taylor WR,Sharifi I

更新日期：2018-06-06 00:00:00

abstract：:A series of amides derived from vanillic acid were obtained by coupling reactions using PyBOP ((Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate) and DCC (Dicyclohexylcarbodiimide) coupling reagents. These were submitted to biological evaluation for species of Candida, Staphylococcus, and Pseudomonas...

journal_title：BioMed research international

authors： Santos Oliveira AJM,de Castro RD,Pessôa HLF,Wadood A,de Sousa DP

更新日期：2019-04-15 00:00:00

abstract：:Approximately 40% of patients admitted to the medical intensive care unit (ICU) require mechanical ventilation. An accurate prediction of successful extubation in patients is a key clinical problem in ICU due to the fact that the successful extubation is highly associated with prolonged ICU stay. The prolonged ICU sta...

journal_title：BioMed research international

authors： Tu CS,Chang CH,Chang SC,Lee CS,Chang CT

更新日期：2018-01-04 00:00:00

abstract：:Vascular aging, a specific type of organic aging, is related to age-dependent changes in the vasculature, including atherosclerotic plaques, arterial stiffness, fibrosis, and increased intimal thickening. Vascular aging could influence the threshold, process, and severity of various cardiovascular diseases, thus makin...

journal_title：BioMed research international

authors： Lin X,Zhan JK,Wang YJ,Tan P,Chen YY,Deng HQ,Liu YS

更新日期：2016-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a critical public health and socioeconomic problem worldwide. The herb pair Astragali Radix (AR)-Radix Angelica Sinensis (RAS) is a common prescribed herbal formula or is added to other Chinese medicine prescriptions for traumatic brain injury (TBI) treatment. However, the underlying me...

journal_title：BioMed research international

authors： Xie G,Peng W,Li P,Xia Z,Zhong Y,He F,Tulake Y,Feng D,Wang Y,Xing Z

更新日期：2018-11-25 00:00:00

abstract：Background:Previous studies have investigated the association between the use of bisphosphonates and the development of breast cancer, which presented controversial results. Thus, this meta-analysis was conducted to summarize the current evidence of the association of bisphosphonate use with breast cancer risk. Method...

journal_title：BioMed research international

authors： Peng R,Liang X,Zhang G,Yao Y,Chen Z,Pan X,Wang J,Liu G

更新日期：2020-10-06 00:00:00

abstract：Background:In patients with reduced systolic function, the natriuretic peptide system affects heart failure (HF) progression, but the expression of key activating (corin) and degrading enzymes (neprilysin) is not well understood. Methods and Results:This pilot study (n=48) compared plasma levels of corin, neprilysin, ...

journal_title：BioMed research international

authors： Zaidi SS,Ward RD,Ramanathan K,Yu X,Gladysheva IP,Reed GL

更新日期：2018-07-26 00:00:00

abstract：:Ultrasound tomography (UST) image segmentation is fundamental in breast density estimation, medicine response analysis, and anatomical change quantification. Existing methods are time consuming and require massive manual interaction. To address these issues, an automatic algorithm based on GrabCut (AUGC) is proposed i...

journal_title：BioMed research international

authors： Wu S,Yu S,Zhuang L,Wei X,Sak M,Duric N,Hu J,Xie Y

更新日期：2017-01-01 00:00:00

abstract：:Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices. Measuring TFA is an arduous task because of the need for fat biopsies. This study identifies a...

journal_title：BioMed research international

authors： Abraham RA,Bahl VK,Parshad R,Seenu V,Roy A,Golandaz S,Dorairaj P,Ramakrishnan L

更新日期：2013-01-01 00:00:00

abstract：:Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is r...

journal_title：BioMed research international

authors： Song Y,Chen Y,Li Y,Lyu X,Cui J,Cheng Y,Zheng T,Zhao L,Zhao G

更新日期：2019-04-17 00:00:00

abstract：Objective:To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods:CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and...

journal_title：BioMed research international

authors： Wang H,Nie P,Dong C,Li J,Huang Y,Hao D,Xu W

更新日期：2018-03-06 00:00:00

abstract：:Introduction. Pelvic organ prolapse (POP) and urinary incontinence (UI) have increasing prevalence in the elderly population. The aim of this study was to compare the comorbidities of these procedures between <70 y/o and ≥70 y/o patients. Materials and Methods. In our retrospective study over a period of 2.5 years, 40...

journal_title：BioMed research international

authors： Joukhadar R,Wöckel A,Herr D,Paulus V,Radosa J,Hamza A,Solomayer E,Baum S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Given its propensity to metastasize, and lack of effective therapies for most patients with advanced disease, early detection of melanoma is a clinical imperative. Different computer-aided diagnosis (CAD) systems have been proposed to increase the specificity and sensitivity of melanoma detection. Although s...

journal_title：BioMed research international

authors： Jaworek-Korjakowska J,Kłeczek P

更新日期：2016-01-01 00:00:00

abstract：:Aldosterone synthase (CYP11B2) is a key enzyme for the biosynthesis of aldosterone, which plays a significant role for the regulation of blood pressure. Excess aldosterone can cause the dysregulation of the renin-angiotensin-aldosterone system (RAAS) and lead to hypertension. Therefore, research and development of CYP...

journal_title：BioMed research international

authors： Luo G,Lu F,Qiao L,Chen X,Li G,Zhang Y

更新日期：2016-01-01 00:00:00

abstract：Objective:To investigate the effects of arteriovenous thrombolysis combined with mechanical thrombectomy on clinical efficacy, neurological function, and the changes of nerve injury markers of acute cerebral infarct (ACI) patients. Methods:A total of 143 cases with ACI admitted to our hospital from June 2017 to June 2...

journal_title：BioMed research international

authors： Ding T,Tang L,Hu B,Yuan J,Li X,Wen J

更新日期：2020-10-09 00:00:00

abstract：Purpose of Review:Transversus abdominis plane (TAP) block is a regional technique for analgesia of the anterolateral abdominal wall. This review highlights the nomenclature system and recent advances in TAP block techniques and proposes directions for future research. Recent Findings:Ultrasound guidance is now conside...

journal_title：BioMed research international

authors： Tsai HC,Yoshida T,Chuang TY,Yang SF,Chang CC,Yao HY,Tai YT,Lin JA,Chen KY

更新日期：2017-01-01 00:00:00

abstract：:Heart failure commonly results from an irreparable damage due to cardiovascular diseases (CVDs), the leading cause of morbidity and mortality in the United States. In recent years, the rapid advancements in stem cell research have garnered much praise for paving the way to novel therapies in reversing myocardial injur...

journal_title：BioMed research international

authors： Sheng CC,Zhou L,Hao J

更新日期：2013-01-01 00:00:00

abstract：:Introduction. The aim of this study was to investigate the utility of ultrasonography (US) for predicting and assessing the effectiveness of extracorporeal shock wave therapy (ESWT) in insertional Achilles tendinopathy (IAT). Methods. A total of 42 patients with an established diagnosis of chronic IAT were examined by...

journal_title：BioMed research international

authors： Cheng Y,Zhang J,Cai Y

更新日期：2016-01-01 00:00:00

abstract：:Neuroendocrine tumors (NETs) are tumors originated from neuroendocrine cells in the body. The localization and the detection of the extent of NETs are important for diagnosis and treatment, which should be individualized according to the tumor type, burden, and symptoms. Molecular imaging of NETs with high sensitivity...

journal_title：BioMed research international

authors： Wang L,Tang K,Zhang Q,Li H,Wen Z,Zhang H,Zhang H

更新日期：2013-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/6935123.]. ...

journal_title：BioMed research international

authors： Pruimboom L,Ruiz-Núñez B,Raison CL,Muskiet FAJ,Freese J

更新日期：2017-01-01 00:00:00

abstract：:Preoperative 5-fluorouracil- (5-FU-) based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, the effect of 5-FU-based chemoradiotherapy on CRC is limited due to the development of chemoradiation resistance (CRR), and the molecular mechanisms underlying this resistance are...

journal_title：BioMed research international

authors： Xiong W,Ai YQ,Li YF,Ye Q,Chen ZT,Qin JY,Liu QY,Wang H,Ju YH,Li WH,Li YF

更新日期：2017-01-01 00:00:00

abstract：:By measuring messenger RNA levels for all genes in a sample, RNA-seq provides an attractive option to characterize the global changes in transcription. RNA-seq is becoming the widely used platform for gene expression profiling. However, real transcription signals in the RNA-seq data are confounded with measurement and...

journal_title：BioMed research international

authors： Li L,Xiong M

更新日期：2015-01-01 00:00:00

abstract：:Contrast-induced acute kidney injury (CI-AKI) is commonly defined as a decline in kidney function occurring in a narrow time window after administration of iodinated contrast material. The incidence of AKI after contrast material administration greatly depends on the specific definition and cutoff values used. Althoug...

journal_title：BioMed research international

authors： Meinel FG,De Cecco CN,Schoepf UJ,Katzberg R

更新日期：2014-01-01 00:00:00

abstract：Purpose:To explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression. Methods:12 female freshmen with depression were filtered by the Beck Depression I...

journal_title：BioMed research international

authors： Zhao S,Chi A,Yan J,Yao C

更新日期：2020-02-27 00:00:00