Abstract:
:Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices. Measuring TFA is an arduous task because of the need for fat biopsies. This study identifies a tissue, which can be easily accessed for analytical measurement of trans fatty acid. In this cross-sectional study, fatty acid in adipose tissue, cheek epithelium, and blood samples were assessed by gas chromatography. Spearman correlation coefficient was computed to study the correlation of fatty acid distribution among the three tissues. The correlation coefficient of total trans fatty acid between cheek epithelium and serum was 0.30 (P < 0.02) and between cheek epithelium and adipose tissue was 0.33 (P < 0.019). This study is the first to report trans fatty acid profile in cheek epithelium giving scope for utilizing the cheek epithelium as a tissue for objective assessment of trans fatty acid intake.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Abraham RA,Bahl VK,Parshad R,Seenu V,Roy A,Golandaz S,Dorairaj P,Ramakrishnan Ldoi
10.1155/2013/276174subject
Has Abstractpub_date
2013-01-01 00:00:00pages
276174eissn
2314-6133issn
2314-6141journal_volume
2013pub_type
杂志文章abstract::Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/453469
更新日期:2015-01-01 00:00:00
abstract:Background:Existing literature suggests that an association exists between coronary artery disease (CAD) and carpal tunnel syndrome (CTS), but few researchers have explored whether CTS is a risk for CAD. Materials and Methods:This large case-control study explored the association between CTS and CAD, using health insu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3171925
更新日期:2019-03-03 00:00:00
abstract::The genus Methylobacterium is composed of pink-pigmented facultative methylotrophic (PPFM) bacteria, which are able to synthesize carotenoids and grow on reduced organic compounds containing one carbon (C1), such as methanol and methylamine. Due to their high phenotypic plasticity, these bacteria are able to colonize ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/909016
更新日期:2015-01-01 00:00:00
abstract::Ischemia/reperfusion (I/R) injury remains a major complication of liver resection, transplantation, and hemorrhagic shock. Although the mechanisms that contribute to hepatic I/R are complex and diverse involving the interaction of cell injury in hepatocytes, immune cells, and endothelium, mitochondrial dysfunction is ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/183469
更新日期:2015-01-01 00:00:00
abstract:Background:It is unclear whether computer navigation can improve the accuracy and reliability of targeted lower limb alignment correction following open-wedge high tibial osteotomy (HTO). This meta-analysis was designed to compare the accuracy and reliability of limb alignment correction between computer navigated and ...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2017/3803457
更新日期:2017-01-01 00:00:00
abstract::Diabetes mellitus is a major health problem that affects a patient's life quality throughout the world due to its worst complications. It was recognized that chronic hyperglycemia with oxidative stress was the major cause of male infertility. Echinacea purpurea ethanol extract (EE) contains phenolic acid and isobutyla...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4237354
更新日期:2018-08-30 00:00:00
abstract::Tau tubulin kinase 2 (TTBK2) is a kinase known to phosphorylate tau and tubulin. It has recently drawn much attention due to its involvement in multiple important cellular processes. Here, we review the current understanding of TTBK2, including its sequence, structure, binding sites, phosphorylation substrates, and ce...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/575170
更新日期:2015-01-01 00:00:00
abstract::The present study showed that oral mushroom beta-glucan treatment significantly increased IFN-γ mRNA expression but significantly reduced COX-2 mRNA expression within the lung. For LLC tumor model, oral Ganoderma lucidum or Antrodia camphorata polysaccharides treatments significantly reduced TGF-β production in serum....
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/604385
更新日期:2015-01-01 00:00:00
abstract::Protein phosphorylation is one of the most widespread regulatory mechanisms in eukaryotes. Over the past decade, phosphorylation site prediction has emerged as an important problem in the field of bioinformatics. Here, we report a new method, termed Random Forest-based Phosphosite predictor 2.0 (RF-Phos 2.0), to predi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3281590
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Although expression of miR-200s is aberrant in liver fibrosis, its role in liver fibrogenesis still remains unknown. Here, we investigated the role of miR-200c in the activation of human hepatic stellate cells (HSCs) and induction of liver fibrosis. METHODS:We engineered human HSCs (LX2 cell line) to stably...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2670658
更新日期:2017-01-01 00:00:00
abstract::The myostatin (MSTN) is a known negative growth regulator of skeletal muscle. The mutated myostatin showed a double-muscular phenotype having a positive significance for the farmed animals. Consequently, adequate information is not available in the teleosts, including farmed rohu carp, Labeo rohita. In the absence of ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/7562368
更新日期:2016-01-01 00:00:00
abstract::As the heart transitions from one exercise intensity to another, changes in cardiac output occur, which are modulated by alterations in force development and calcium handling. Although the steady-state force-calcium relationship at various heart rates is well investigated, regulation of these processes during transiti...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/468548
更新日期:2015-01-01 00:00:00
abstract:AIM:To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. METHODS:The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Methylthiazol tetrazoliu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/687826
更新日期:2014-01-01 00:00:00
abstract::Growing evidence indicates that immune-related biomarkers play an important role in tumor processes. This study investigates immune-related gene expression and its prognostic value in lung squamous cell carcinoma (LUSC). A cohort of 493 samples of patients with LUSC was collected and analyzed from data generated by th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5024942
更新日期:2020-06-27 00:00:00
abstract::Impact of bone mesenchymal stem cell (BMSC) transfusion on chronic smoking-induced lung inflammation is poorly understood. In this study, a rat model of smoking-related lung injury was induced and the rats were treated with vehicle or BMSCs for two weeks. Different subsets of CD4+ T cells, cytokines, and anti-elastin ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/932923
更新日期:2015-01-01 00:00:00
abstract::HPV genotypes have distinct distributions among various ethnic populations worldwide. In December 2013, 237 and 159 cervical samples were collected from Hani and Han ethnic women, respectively, in Mojiang, a rural county in southern Yunnan. The overall HPV infection rate (21.1%) among the Hani women was significantly ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/314815
更新日期:2015-01-01 00:00:00
abstract:Background:According to several studies, the autoimmune response may lead to osteoarthritis and dyslipidemia and may affect the homeostasis of the human body's internal environment and then cause its own immune regulation. Consequently, the risk of osteoarthritis might be increased by dyslipidemia, but this association...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2020/3105248
更新日期:2020-02-15 00:00:00
abstract::Keratinases are proteolytic enzymes predominantly active when keratin substrates are available that attack disulfide bridges in the keratin to convert them from complex to simplified forms. Keratinases are essential in preparation of animal nutrients, protein supplements, leather manufacture, textile processing, deter...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/140726
更新日期:2015-01-01 00:00:00
abstract::Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite effect under other...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/201475
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Prelacteal feed (feeding any other substance before first breastfeeding) appears to be common despite its harmful effects. By definition a child provided with prelacteal feed (PLF) is not exclusively breastfed and PLF has many implications for the success and early initiation of breastfeeding. Objectives. To...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/258470
更新日期:2014-01-01 00:00:00
abstract::Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date. 70 patients with severe mitral regurgitation, additional pulmonary hy...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6817832
更新日期:2018-03-14 00:00:00
abstract:PURPOSE:To investigate whether P. acnes could induce disc degeneration and Modic changes when inoculated into the discs of rabbits. METHOD:A wild-type strain of P. acnes isolated from a patient associated with Modic change and disc degeneration was inoculated into the intervertebral discs of rabbits. Meanwhile, S. aur...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/9612437
更新日期:2016-01-01 00:00:00
abstract::High-dose melphalan (200 mg/m(2)) as conditioning regimen followed by autologous stem cell transplantation (ASCT) rescue has been established as a standard treatment for patients with multiple myeloma (MM) younger than 65 years of age. However, the role of ASCT in elderly patients older than 65 years remains controver...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/394792
更新日期:2014-01-01 00:00:00
abstract::Objective. This study aims to extract motor ingredients through data mining from wearable sensors in a virtual reality goal-directed shoulder rehabilitation (GDSR) system and to examine their effects toward clinical assessment. Design. A single-group before/after comparison. Setting. Outpatient research hospital. Subj...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2016/7075464
更新日期:2016-01-01 00:00:00
abstract::Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/615312
更新日期:2014-01-01 00:00:00
abstract::Magnetic resonance imaging (MRI) based on the ferritin heavy chain 1 (FTH1) reporter gene has been used to trace stem cells. However, whether FTH1 expression is affected by stem cell differentiation or whether cell differentiation is affected by reporter gene expression remains unclear. Here, we explore the relationsh...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1978602
更新日期:2018-06-26 00:00:00
abstract::This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The interventi...
journal_title:BioMed research international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1155/2014/102164
更新日期:2014-01-01 00:00:00
abstract::A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt.3243A>G ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1286480
更新日期:2018-11-13 00:00:00
abstract::Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by bone loss. Degree of inflammation has been identified as an important initiator of skeletal damage in RA. Iguratimod (T-614) is an anti-inflammatory agent which has been reported to show the inhibitory effect of bone destruction in RA. Ho...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/4901591
更新日期:2018-02-19 00:00:00
abstract::Giardia duodenalis, is often seen as an opportunistic pathogen and one of the major food and waterborne parasites. Some insights of Giardia infestation in a diarrhoea-prone population were investigated in the present study. Our primary goal was to understand the interaction of this parasite with other pathogens during...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/786480
更新日期:2014-01-01 00:00:00